Analysis of advanced diffusion models assessing white matter microstructure in Alzheimer’s disease by Minli Lv, Kongcai Zhan, Jie Yang, Yan Li, Yutong Li, Xiaoya Xu, Limei Han, Hao Feng, Jianquan Zhong

“…Significant correlations were observed between neuropsychological scores and diffusion parameters across multiple brain regions. Specifically, the diffusion metrics most strongly related to MMSE and MoCA scores included RTOP, RTAP, ICVF, and FA, with RTOP and RTAP exhibiting the strongest relationship to cognitive function. …”
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Development and Application of Small Object Visual Recognition Algorithm in Assisting Safety Management of Tower Cranes by Xiao Sun, Xueying Lu, Yao Wang, Tianxiao He, Zhenghong Tian

“…To address these limitations, the algorithm is enhanced by incorporating an additional small object detection layer, implementing an attention mechanism, and modifying the loss function. The enhanced YOLOv5s model achieved precision and recall rates of 96.00%, with average precision (AP) values of 96.42% at an IoU of 0.5 and 62.02% across the range of IoU values from 0.5 to 0.95. …”
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Chloride intracellular channel proteins respond to heat stress in Caenorhabditis elegans. by Jun Liang, Yakov Shaulov, Cathy Savage-Dunn, Stephane Boissinot, Tasmia Hoque

“…Chloride intracellular channel proteins (CLICs) are multi-functional proteins that are expressed in various cell types and differ in their subcellular location. …”
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OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development. by Hidetoshi Komatsu, Michael Y Chao, Jonah Larkins-Ford, Mark E Corkins, Gerard A Somers, Tim Tucey, Heather M Dionne, Jamie Q White, Khursheed Wani, Mike Boxem, Anne C Hart

“…The mammalian DOS-motif protein Deltalike1 (DLK1) can substitute for OSM-11 in C. elegans development, suggesting that DOS-motif function is conserved across species. We hypothesize that C. elegans OSM-11 and homologous proteins act as coactivators for Notch receptors, allowing precise regulation of Notch receptor signaling in developmental programs in both vertebrates and invertebrates.…”
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A compact encoding of the genome suitable for machine learning prediction of traits and genetic risk scores by Yasaman Fatapour, James P. Brody

“…We also used the AutoML function in regression mode to predict the height of people based on their age and genotype. …”
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Causal ECGNet: leveraging causal inference for robust ECG classification in cardiac disorders by Mei Wang, Cong You, Wei Zhang, Zibo Xu, Qi Liang, Qiang Li

“…Experimental results demonstrate that our method achieves significant improvements in classification accuracy and robustness across four benchmark ECG datasets, outperforming existing methods. …”
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NEK2 is a potential pan-cancer biomarker and immunotherapy target by Lanyue Zhang, Yang Li, Juexiao Deng, Wenxin Liao, Tingting Liu, Fujin Shen

“…Therefore, we evaluated the prognostic value of NEK2 in 33 cancers to elucidate the potential function of NEK2 in pan-cancers. Methods We investigated the role of NEK2 in pan-cancers utilizing The Cancer Genome Atlas (TCGA) and the Genotype-Tissue Expression (GTEx) database. …”
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Brown and beige adipose tissue‐derived metabokine and lipokine inter‐organ signalling in health and disease by Anna Malicka, Aysha Ali, Amanda D. V. MacCannell, Lee D. Roberts

“…Brown and beige adipose tissues have been identified as sources of metabokines and lipokines, which influence diverse metabolic pathways, such as fatty acid β‐oxidation, mitochondrial function and glucose homeostasis, across a range of tissues, including skeletal muscle, adipose tissue and heart. …”
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Non‐Respiratory Extracellular Electron Transfer Competes with Nitrogenase for Electrons in Rhodopseudomonas Palustris by Xuewen Liu, Panqing Qi, Weipeng Fan, Wuyang Liu, Xingjiang Li, Yong Nie, Xiao‐Lei Wu

“…Although extracellular electron acceptors can function as a component of the electron transport chain, providing energy for chemotrophic nitrogen fixation via extracellular respiration, the function and mechanism of outward EET in photosynthetic diazotrophs remain unclear. …”
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Cognitive cascades: How to model (and potentially counter) the spread of fake news. by Nicholas Rabb, Lenore Cowen, Jan P de Ruiter, Matthias Scheutz

“…We conduct an analysis of the cognitive cascade model with our simple cognitive function across various graph topologies and institutional messaging patterns. …”
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Exploration of the metabolomic mechanisms of postmenopausal hypertension induced by low estrogen state by Yao Li, Hui Xin, Zhexun Lian, Wei Zhang

“…Notable differences in blood pressure parameters and aortic tissue metabolites were observed across the experimental groups. Specifically, metabolites that were differentially expressed, particularly L-alpha-aminobutyric acid (L-AABA), showed potential as a biomarker for postmenopausal hypertension, potentially exerting a protective function through macrophage activation and vascular remodeling. …”
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Non-Invasive Differential Temperature Monitoring Using Sensor Array for Microwave Hyperthermia Applications: A Subspace-Based Approach by Ji Wu, Fan Yang, Jinchuan Zheng, Hung T. Nguyen, Rifai Chai

“…The temperature-dependent dielectric properties of breast tissues are modeled using data from porcine tissues, and a sigmoid function is employed to create realistic temperature transition zones in the numerical breast phantom. …”
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Depth-dependent changes in collagen organization in the human peripapillary sclera. by Jacek K Pijanka, Martin T Spang, Thomas Sorensen, Jun Liu, Thao D Nguyen, Harry A Quigley, Craig Boote

“…The aim of the current work was to map the anisotropic collagen structure of the normal human peripapillary sclera as a function of tissue depth.<h4>Methods</h4>Wide-angle x-ray scattering was used to quantify collagen fibril orientation at 0.5 mm intervals across six 150 μm-thick serial sections through the peripapillary sclera of eight normal European-derived human eyes. …”
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Characterization of the tectonic structures on the Tibetan Plateau using gravity anomaly data and an improved edge detection method by Zhixin Xue, Jian Fang, Dongmei Guo, Panpan Zhang

“…To overcome these limitations, we present an improved method called the hyperbolic tangent function with Gaussian envelope constraints on the horizontal gravity gradient tilt angle (THTAHG) that is based on the tilt angle of the horizontal gravity gradient and the hyperbolic tangent (TANH) function under Gaussian envelope constraints. …”
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Effects of atractylodin and β-Eudesmol on P-glycoprotein and Caco-2 cells permeability by Artitaya Thiengsusuk, Wiriyaporn Sumsakul, Kesara Na–Bangchang

“…However, neither of the compounds were P-gp inhibitors nor modulators of the expression of MDR-1 mRNA, and P-gp function. Only a slight inhibitory effect was observed with atractylodin exposure at 160 µM for 24 hrs. …”
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An enhanced CNN-Bi-transformer based framework for detection of neurological illnesses through neurocardiac data fusion by Kavita Rawat, Trapti Sharma

“…The neurocardiac data fusion has been found to provide additional insights into the relationship between brain and cardiac function in neurological conditions, which could potentially lead to more accurate diagnosis and personalized treatment options. …”
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Dual FOPID-neural network controller based on fast grey wolf optimizer: application to two-inputs two-outputs helicopter by Amar Rezoug, Jamshed Iqbal, Abdelkrim Nemra

“…The first scenario involved nine benchmark functions across thirty trials. Results demonstrated that the FGWO offered superior performance in terms of robustness and proximity to the global minimum compared to the GWO. …”
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Role of Lysophosphatidic Acid in Neurological Diseases: From Pathophysiology to Therapeutic Implications by Simona Dedoni, Valeria Avdoshina, Maria C. Olianas, Pierluigi Onali

“…This review synthesizes evidence linking LPA’s function in neurological diseases such as traumatic brain injury, spinal cord injury, cerebellar ataxia, cerebral ischemia, seizures, Huntington’s disease, amyotrophic lateral sclerosis, Hutchinson-Gilford progeria syndrome, autism, migraine, and human immunodeficiency virus (HIV)-associated complications Despite recent advances, the specific mechanisms underlying LPA’s actions in various neurological disorders remain unknown, and further research is needed to understand the distinct roles of LPA across multiple disease conditions, as well as to investigate the therapeutic potential of targeting LPA receptors in these pathologies. …”
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Evolutionary rewiring of bacterial regulatory networks by Tiffany B. Taylor, Geraldine Mulley, Liam J. McGuffin, Louise J. Johnson, Michael A. Brockhurst, Tanya Arseneault, Mark W. Silby, Robert W. Jackson

“…Consequently, evolutionary resilience is built into gene networks – homology between regulators can potentially allow rapid rescue of lost regulatory function across distant regions of the genome. …”
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Design of Complex Vector Current Controller for High-power Induction Motor by SUN Jiawei, JIANG Tao, QU Shijian, ZHOU Zheng, LI Jian

“…Across the entire speed range, the cross-coupling error is reduced by more than 80 percentage points, while the dynamic response speed is improved by more than 45%.…”
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