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  1. 401

    Characterization of Key Metabolic Markers in Hongqujiu Across Different Aging Years Using Metabolomics by Yiyang Cai, Sunan Yan, Simei Huang, Bin Yang, Wenlan Mo, Lishi Xiao, Xiangyou Li, Zhiwei Huang

    Published 2025-05-01
    “…In this study, an untargeted metabolomics approach based on gas chromatography–mass spectrometry (GC-MS) and liquid chromatography–mass spectrometry (LC-MS) was applied to systematically analyze the volatile compounds (VOCs) and non-volatile compounds (NVCs) in Hongqujiu across different aging years for the first time. The analysis identified a total of 262 VOCs and 2564 NVCs in samples of Hongqujiu aged for six distinct years. …”
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  2. 402

    Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons by Jones, Auriane G., Schaal, Gauthier, Boyé, Aurélien, Creemers, Marie, Derolez, Valérie, Desroy, Nicolas, Fiandrino, Annie, Mouton, Théophile L., Simier, Monique, Smith, Niamh, Ouisse, Vincent

    Published 2024-12-01
    “…Here, we analyze a dataset composed of macrobenthic invertebrate abundances and environmental variables (hydro-morphology, water, sediment and macrophytes) gathered across 29 Mediterranean coastal lagoons located in France, to characterize the main drivers of community composition and structure. …”
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  3. 403

    MiRNA expression profiling and clinical implications in prostate cancer across various stages by Zhengjie Xiang, Tao Lin, Jian Ling, Zuhuan Xu, Ruizhen Huang, Honglin Hu

    Published 2025-03-01
    “…Abstract This study aims to screen and identify microRNA (miRNA) expression profiles across different stages of prostate cancer (PCa) and benign prostatic hyperplasia (BPH) using high-throughput sequencing. …”
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  4. 404

    The Role of Plant Evolutionary History in Shaping the Variation in Specific Leaf Area Across China by Minyue Si, Caiyi Zhang, Chunzhu Xiang, Mingxia Jiang, Linwei Guo, Junjiong Shao

    Published 2025-04-01
    “…ABSTRACT Specific leaf area (SLA, leaf area per unit leaf dry mass) occupies a central position in both community assembly and ecosystem functioning. Although SLA has significant phylogenetic signals, how and to what extent the evolutionary history influences the variation in SLA remain poorly understood. …”
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  5. 405

    Correlation of the intestinal flora and its metabolites with the colonic transport function in functional constipation by Lunan Hu, Qihong Liu, Xiao Ke, Peilin Zhao, Wenyi Fang, Yan Ren

    Published 2025-05-01
    “…However, the microbiota composition associated with FC and the mechanisms by which metabolites influence gut motility remain poorly understood.MethodsStool samples were collected from 60 participants (20 FC patients with delayed colonic transit time, 20 FC patients with normal colonic transit time, and 20 healthy controls), and macrogenomics and metabolomics were used to assess the differences in the microbiota and metabolite composition of different colonic transit functions in FC. In addition to assessing clinical symptoms, this study aimed to better understand how intestinal flora contributed to impaired gut motility in FC patients.ResultsSignificant microbiota taxonomic differences were observed across different gut dynamics in FC; Alistipes, Akkermansia, Oscillibacter, Ruthenibacterium, Alistipes_onderdonkii, and Ruthenibacterium_lactatiformans were key bacteria in FC patients with delayed colonic transit time; Roseburia and Klebsiella_pneumoniae were key bacteria in FC patients with normal colonic transit time; and Escherichia, Enterobacter, Escherichia_coli, Ruminococcus gnavus, Enterobacter_cloacae_complex, and Megamonas_funiformis were the key organisms in healthy controls. …”
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  6. 406

    Impaired spatial dynamic functional network connectivity and neurophysiological correlates in functional hemiparesis by E. Premi, V. Cantoni, A. Benussi, A. Iraji, V.D. Calhoun, D. Corbo, R. Gasparotti, M. Tinazzi, B. Borroni, M. Magoni

    Published 2025-01-01
    “…The aim of this work was to assess static functional connectivity (large-scale) networks and dynamic brain states, which represent distinct dFNC patterns that reoccur in time and across subjects. …”
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  7. 407
  8. 408

    Comparative Analysis of Gut Microbiota Diversity Across Different Digestive Tract Sites in Ningxiang Pigs by Wangchang Li, Xianglin Zeng, Lu Wang, Lanmei Yin, Qiye Wang, Huansheng Yang

    Published 2025-03-01
    “…Comparative metabolic abundance analysis highlighted distinct functional profiles across tissues, with significant differences observed in pathways related to the immune system, energy metabolism, lipid metabolism, transcriptional and translational regulation, and aging. …”
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  9. 409
  10. 410

    Restoration of tropical dry forest: an analysis of constraints and successes across a highly threatened biome by Natalia Mesa-Sierra, Marinés de la Peña-Domene, Julio Campo, Christian P. Giardina

    Published 2025-01-01
    “…We used a meta-analytical approach to compare survival, growth, and measures of ecosystem function in restored systems and either intact reference baselines or impacted controls. …”
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  11. 411

    Prevalence and factors linked to renal involvement in prediabetes patients across Europe in the ePREDICE trial by Sebastián Mas-Fontao, Esther Civantos, Nisa Boukichou, Juan A. Moreno, Jaakko Tuomilehto, Rafael Gabriel, Jesús Egido

    Published 2024-12-01
    “…Abstract This sub-analysis of the ePREDICE trial, investigated the prevalence and determinants of renal complications, specifically glomerular hyperfiltration, albuminuria, and reduced kidney function, in individuals with prediabetes (PD). The cohort consisted of 967 participants from diverse backgrounds across seven countries. …”
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  12. 412

    Vegetation Productivity in Xinjiang’s Ecosystems: Responses to Natural and Human Factors across Basins and Land Covers by Hao Yuan, Rui Yang, Jianjun Wu, Jianhang Zhang, Litao Zhou

    Published 2025-01-01
    “…Net primary productivity (NPP) serves as a key indicator of plant carbon sequestration capacity, effectively delineating changes in terrestrial ecosystem structure and function. However, there is still a lack of comprehensive multiscale nested analysis of NPP dynamics across different basins and land cover types in Xinjiang. …”
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  13. 413

    Computing Nonlinear Power Spectra Across Dynamical Dark Energy Model Space with Neural ODEs by Peter L. Taylor

    Published 2025-08-01
    “…Using synthetic ΛCDM data, I train a neural ordinary differential equation (ODE) to infer the evolution of the nonlinear matter power spectrum as a function of the background expansion and mean matter density across ∼9 Gyr of cosmic evolution. …”
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  14. 414

    Acute ischaemia and gap junction modulation modify propagation patterns across Purkinje-myocardial junctions by Richard J. Jabbour, Elham Behradfar, Elham Behradfar, Michael Debney, Anders Nygren, Anders Nygren, Adam Hartley, Igor Efimov, Mélèze Hocini, Mélèze Hocini, Nicholas S. Peters, Fu Siong Ng, Edward J. Vigmond, Edward J. Vigmond, Edward J. Vigmond

    Published 2025-05-01
    “…Pharmacological gap junction modulation may alter propagation patterns across PMJs and may be used as a therapeutic strategy for Purkinje system associated arrhythmias.…”
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  15. 415

    Electron transport across the cell envelope via multiheme c-type cytochromes in Geobacter sulfurreducens by Media Zakizadeh Tabari, Allon I. Hochbaum

    Published 2025-07-01
    “…We examine the state of understanding of their physiological function, their structural features, expression patterns, and essentiality under various respiratory conditions. …”
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  16. 416

    GRA12 is a common virulence factor across Toxoplasma gondii strains and mouse subspecies by Francesca Torelli, Simon Butterworth, Eloise Lockyer, Ana N. Matias, Franziska Hildebrandt, Ok-Ryul Song, Jennifer Pearson-Farr, Moritz Treeck

    Published 2025-04-01
    “…To identify virulence factors that function across different parasite isolates and mouse strains that differ in susceptibility to infection, we performed systematic pooled in vivo CRISPR-Cas9 screens targeting the Toxoplasma secretome. …”
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  17. 417

    A study of heart–brain information flow across sleep stages using transfer entropy by Shumei Zhu, Jingyi Yu, Yuman Luo, Jun Wang

    Published 2025-04-01
    “…Heart–brain coupling, regulated by the autonomic and central nervous systems, plays a vital role in maintaining physiological homeostasis, emotional regulation, and cognitive function. Understanding this dynamic interaction offers valuable insights into the coordination of physiological processes and the diagnosis of cardiovascular and neurological disorders. …”
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  18. 418

    Contextual ITSM Adoption Across Educational Levels: A University and a Secondary School in Jakarta by Marcel Marcel, Nur Chalik Azhar

    Published 2025-06-01
    “…This research investigates contextual ITSM adaptation across educational levels through a comparative case study of a university and secondary school in Jakarta. …”
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  19. 419

    Astrocyte proliferation in the hippocampal dentate gyrus is suppressed across the lifespan of dystrophin‐deficient mdx mice by Kimberley A. Stephenson, Polly Peters, Mark G. Rae, Dervla O'Malley

    Published 2025-04-01
    “…Astrocytes are the most abundant cell type in the brain and are crucial in supporting neuronal function, such that loss of these cells is likely to contribute to hippocampal dysfunction reported in mdx mice.…”
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  20. 420