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3901
Glutamate Receptor Signaling in Retina Müller Cells: Plausible Role in Neurodegeneration
Published 2025-02-01“…An exquisite interplay between glutamate receptor signaling and glutamate transporter expression and function is fundamental for the integrity and proper function of the retina. …”
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3902
Brain-Inspired Multisensory Learning: A Systematic Review of Neuroplasticity and Cognitive Outcomes in Adult Multicultural and Second Language Acquisition
Published 2025-06-01“…Background: Multicultural education and second-language acquisition engaged neural networks, supporting executive function, memory, and social cognition in adulthood, represent powerful forms of brain-inspired multisensory learning. …”
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3903
MalHAPGNN: An Enhanced Call Graph-Based Malware Detection Framework Using Hierarchical Attention Pooling Graph Neural Network
Published 2025-01-01“…Firstly, to ensure semantic richness, a Bidirectional Encoder Representations from Transformers-based (BERT) attribute-enhanced function embedding method is proposed for the extraction of node attributes in the function call graph. …”
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3904
Mesenchymal Stem Cell–Sourced Exosomes as Potentially Novel Remedies for Severe Dry Eye Disease
Published 2025-01-01“…Severe dry eye disease (DED) is an inflammatory condition characterized by a lack of sufficient moisture or lubrication on the surface of the eye, significantly impacting the quality of life and visual function. Since detrimental immune response is crucially responsible for the development and aggravation of DED, therapeutic agents which modulate phenotype and function of eye-infiltrated inflammatory immune cells could be used for the treatment of severe DED. …”
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3905
Thermal and Magnetic Properties of Thin Film Topological Insulators
Published 2025-01-01“…Additionally, we explore the variations in the density of states as functions of energy and magnetic field strength. The Fermi energy fluctuations, at a fixed electron concentration, are computed as a function of the applied magnetic field. …”
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3906
Effects of chemotherapy on skeletal muscle mitochondrial oxidative capacity using near-infrared spectroscopy (NIRS): Protocol paper for an observational mixed model repeated measur...
Published 2025-01-01“…We also plan to observe if there is a difference in mitochondrial oxidative capacity between different chemotherapy regimens across different patients. This pilot study will provide information on the feasibility of capturing on/off kinetics mitochondrial function data longitudinally using NIRS in patients newly diagnosed with breast or gynecological cancer, provide preliminary data for future extramural funding, as well as inform the scientific community of results through dissemination via conferences and peer-reviewed journal publications. …”
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3907
Regeneration of the nerves in the aerial cavity with an artificial nerve conduit --reconstruction of chorda tympani nerve gaps-.
Published 2014-01-01“…<h4>Results</h4>Gustatory function was completely restored in all of the patients after the reconstruction. …”
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3908
Risk-Adjusted Deep Reinforcement Learning for Portfolio Optimization: A Multi-reward Approach
Published 2025-05-01“…Instead of relying solely on a singular reward function, our approach integrates three different functions aiming at diverse objectives. …”
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3909
Lipocalin 2 in Obesity and Diabetes: Insights into Its Role in Energy Metabolism
Published 2025-01-01“…Results: LCN2 is widely expressed across various tissues, including immune cells, bone, adipose tissue, liver, kidneys, lung, spleen, and epithelial cells, and exhibits sex- and fat depot-specific expression patterns. …”
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3910
Recovery from Adolescent Anorexia Nervosa and Associations with Diurnal Patterns of Salivary Stress Hormones: A Case Report
Published 2012-01-01“…During illness, her measure of affective problems was outside of the normal range and cortisol and DHEA secretory profiles were significantly elevated across the diurnal period. However, at recovery both her affective state and HPA axis function became comparable to healthy controls. …”
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3911
Audiometry as a predictive proxy for balance dysfunction
Published 2025-04-01“…Here, we probed systematic audiometry and vestibular function on 1115 patients, attending consultation for dizziness and vertigo. …”
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3912
Plasma macrophage migration inhibitory factor and matrix metalloproteinase-9 levels, and their related factors in Alzheimer’s disease
Published 2025-06-01“…In addition, plasma levels of MIF and MMP-9 in patients with AD had no significant correlation with cognitive function. In summary, plasma levels of MIF and MMP-9 in AD patients may be influenced by multiple factors and could vary significantly across different disease stages. …”
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3913
Cognitive impairment in PSP compared with PD: assessment by clinical subtype and longitudinal change
Published 2025-01-01“…The variability of cognitive impairment across clinical subtypes of PSP remains unclear.Objective This study aimed to compare the longitudinal changes in cognitive function between patients with PSP and Parkinson’s disease (PD) and to assess differences in cognitive impairment among PSP subtypes.Methods A retrospective observational study was conducted using neuropsychological testing data from patients with PSP and PD admitted to our hospital.Results The study included 38 patients with PD and 41 patients with PSP (23 PSP-Richardson’s syndrome, 14 PSP-progressive gait freezing (PSP-PGF), 3 PSP-Parkinsonism and 1 PSP-predominant corticobasal syndrome). …”
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3914
Cross-sectional differences of physical and psychosocial measures in low back pain according to pain chronification risk groups
Published 2025-08-01“…Results: The intensity of physical and psychosocial problems differed significantly among the pain chronification risk groups. Physical function also varied across subgroups, with the high-risk group exhibiting the weakest muscle strength and the greatest stiffness. …”
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3915
Typical Changes in Gait Biomechanics in Patients with Subacute Ischemic Stroke
Published 2025-02-01“…It increases the risk of falls, reduces functional independence, and thus affects the quality of life. …”
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3916
Annual Variation Characteristics of Air Conditioning Operating Behavior and Its Impact on Model Application in Office Buildings
Published 2024-11-01“…Based on a dynamic model framework constructed with a three-parameter Weibull function and a time superposition function, this study conducted modeling and analysis of dynamic AC operating behaviors in the same open-plan office across different years. …”
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3917
Salp Swarm Algorithm Optimized A* Algorithm and Improved B-Spline Interpolation in Path Planning
Published 2025-05-01“…The first major improvement involves enhancing the A* algorithm by optimizing its heuristic function through the SSA. The heuristic function combines Chebyshev distance, Euclidean distance, and obstacle density, with the SSA adjusting the weight parameters to maximize efficiency. …”
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3918
Effectiveness of the Roy adaptation model-based nursing intervention in improving physiological, psychological, and social outcomes in patients with Parkinson’s disease
Published 2025-05-01“…Abstract Objective This study aimed to evaluate the effectiveness of a comprehensive nursing intervention based on Roy’s Adaptation Model (RAM) in improving quality of life, psychological adaptation, and social functioning in patients with Parkinson’s disease (PD). …”
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3919
AMPA GluA1-flip targeted oligonucleotide therapy reduces neonatal seizures and hyperexcitability.
Published 2017-01-01“…Due to the critical nature of AMPA-Rs in normal brain function, typical AMPA-R antagonists have deleterious effects on cognition and motor function, highlighting the need for more precise modulators. …”
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3920
The research on full-waveform inversion method and its application based on Hessian operator preprocessing
Published 2025-03-01“…Firstly, the adjoint gradient method is used to iteratively optimize the gradient of the model with respect to the residuals of the observed data when solving the objective function. Secondly, in view of the energy inconsistency gradient amplitudes across space, the diagonal elements of Hessian operator are used to scale the gradient, which ensures that the gradient amplitude is inversely proportional to the sensitivity of the synthesized data, thereby the imaging accuracy in deep and weak reflected areas. …”
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