A patient-centered qualitative evaluation of meaningful change on the NSAA and PUL in Duchenne Muscular Dystrophy by Aviva Gillman, Teofil Ciobanu, Louise Barrett, Evan W. Davies, Alexander P. Murphy, Alex Johnson, Jessica Mills, Phoebe Heinrich, Krystian Przydzial, Bethany Ewens, Gerrit Vandenberg, Stefan Cano, Anna Mayhew

“…For the PUL, participants underscored the importance of maintenance of their functional abilities, and highlighted key themes related to maintaining independence in ADLs, reaching, eating/drinking, and finger function for technology use across score categories.…”
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Soil types create different rhizosphere ecosystems and profoundly affect the growth characteristics of ratoon sugarcane by Xiaoming Wang, Junjun Ma, Chaoxian Fang, Jinghuan Zhu, Shilong Wang, Zuli Yang

“…IntroductionRhizosphere ecological factors play a crucial role in the soil feedback function of ratoon sugarcane. However, limited information exists regarding the differences and relationships among these factors across various soil types (sandy, loam, and clay) and their impact on sugarcane growth and yield characteristics. …”
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Urban air pollution and chronic respiratory diseases in adults: insights from a cross-sectional study by Mohammed M. Alyami, Fahad H. Balharith, Sunil Kumar Ravi, Ravi Shankar Reddy

“…Sensitivity analyses confirmed the robustness of these findings across different analytical scenarios.ConclusionThe study demonstrated a clear and significant association between higher air pollution level exposures and an increased risk of chronic respiratory conditions and reduced lung function. …”
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Vulnerability-Based Economic Loss Rate Assessment of a Frame Structure Under Stochastic Sequence Ground Motions by Zheng Zhang, Yunmu Jiang, Zixin Liu

“…Coherence analysis shows that the function remains relatively stable between 0.3 and 0.6 across the 0–30 Rad/s frequency range. …”
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Angiogenic and Immunomodulatory effects of embryonic stem cell derived mesenchymal stem cells in a murine model of ischemic hindlimb by Do Jung Kim, Young-Nam Youn, Ji Min Kim, Sang-Hyun Lim

“…These changes were observed across all dose groups without significant dose-dependent differences. …”
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Efficacy of different acupuncture therapies on hand dysfunction in post-stroke patients: a systematic review and meta-analysis by Yuxiang Liu, Jing Zhou, Jiawen Zheng, Jing Chen, Jing Chen

“…Primary outcomes were the Brunnstrom Recovery Stage (BRS), Fugl-Meyer Assessment (FMA), and Lindmark scores; secondary outcomes included the Modified Ashworth Scale (MAS), Range of Motion (ROM), Manual Muscle Testing (MMT), and Modified Barthel Index (MBI).ResultsMeta-analyses demonstrated significant improvements in hand function across multiple outcomes: BRS (mean difference [MD] = 0.56, 95% confidence interval [CI]: 0.43–0.69), FMA (MD = 1.24, 95% CI: 0.96–1.53), MAS (MD = −0.48, 95% CI: −0.59 to −0.38), ROM (MD = 0.95, 95% CI: 0.64–1.26), and MBI (MD = 6.70, 95% CI: 4.85–8.55). …”
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MCU expression in hippocampal CA2 neurons modulates dendritic mitochondrial morphology and synaptic plasticity by Katy E. Pannoni, Quentin S. Fischer, Renesa Tarannum, Mikel L. Cawley, Mayd M. Alsalman, Nicole Acosta, Chisom Ezigbo, Daniela V. Gil, Logan A. Campbell, Shannon Farris

“…Differences in MCU expression across cell types and circuits might be a general mechanism to tune mitochondrial function to meet distinct synaptic demands.…”
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Revolutionizing proton exchange membrane fuel cell modeling through hybrid aquila optimizer and arithmetic algorithm optimization by Manish Kumar Singla, S. A. Muhammed Ali, Ramesh Kumar, Pradeep Jangir, Mohammad Khishe, G. Gulothungan, Haitham A. Mahmoud

“…AOAAO demonstrated superior performance across various metrics, achieving an SSE minimum in comparison to other compared algorithm. …”
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YO-AFD: an improved YOLOv8-based deep learning approach for rapid and accurate apple flower detection by Dandan Wang, Dandan Wang, Huaibo Song, Huaibo Song, Huaibo Song, Bo Wang

“…This module was then incorporated into the C2f module within the network’s neck, forming the C2f-IS module, to enhance the model’s ability to extract critical features and fuse features across scales. Additionally, to balance attention between simple and challenging targets, a regression loss function based on Focaler Intersection over Union (FIoU) was used for loss function calculation. …”
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Oxidative stress in the brain is regulated by social status in a highly social cichlid fish by Peter D. Dijkstra, Peter D. Dijkstra, Peter D. Dijkstra, Robert J. Fialkowski, Brady Bush, Ryan Y. Wong, Travis I. Moore, Ashley R. Harvey

“…Social stress can increase reactive oxygen species and derail antioxidant function in the brain, which may contribute to the onset and progression of mental health disorders. …”
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Airborne Constant Ground Resolution Imaging Optical System Design by Zhiqiang Yang, Shizhen Gao, Qianxi Chen, Bohan Wu, Qiang Xu, Lei Gong, Lihong Yang

“…The designed optical system achieves near-diffraction-limited modulation transfer function (MTF) performance across the full field of view, with all dispersion spots consistently confined within the Airy disk at every viewing angle. …”
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Linking cognitive reserve to neuropsychological outcomes and resting-state frequency bands in healthy aging by Vanesa Perez, Vanesa Perez, Vanesa Hidalgo, Vanesa Hidalgo, Alicia Salvador, Alicia Salvador

“…However, the EEG analysis showed that individuals with high CR exhibited lower spectral power in the theta and delta frequency bands across different brain regions, compared to those with low CR.DiscussionThese findings suggest that individuals with high CR tend to function more efficiently, relying on fewer neural resources to sustain cognitive performance. …”
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Sodium-Glucose Cotransporter 2 Inhibitors in Diabetic Kidney Disease and beyond by Zein Alabdin Hannouneh, C. Elena Cervantes, Mohamad Hanouneh, Mohamed G. Atta

“…Further research is needed to explore SGLT2is’ multifaceted mechanisms and potential applications across diverse patient populations and different disease etiologies. …”
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Protocol for CRISPR-based manipulation and visualization of endogenous α-synuclein in cultured mouse hippocampal neurons by Leonardo A. Parra-Rivas, Rohan Sharma, Trinity E. Rust, Hannah O. Bazick, Jared Carlson-Stevermer, Mark J. Zylka, Yuki Ogawa, Subhojit Roy

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Safety assessment of the substance poly(2‐hydroxypropanoic acid), n‐octyl/n‐decyl esters, for use in food contact materials by EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Andrew Chesson, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Laurence Castle, Emma Di Consiglio, Roland Franz, Nicole Hellwig, Stefan Merkel, Maria Rosaria Milana, Eric Barthélémy, Remigio Marano, Ellen Van Haver, Gilles Rivière

“…Instead of providing a 90‐day oral toxicity study, a hydrolysis study in ■■■■■ was submitted to read‐across from the authorised starting substances, ■■■■■ and the ■■■■■. …”
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Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness by Panagiotis Fotiadis, Andrew R. McKinstry-Wu, Sarah M. Weinstein, Philip A. Cook, Mark Elliott, Matthew Cieslak, Jeffrey T. Duda, Theodore D. Satterthwaite, Russell T. Shinohara, Alexander Proekt, Max B. Kelz, John A. Detre, Dani S. Bassett

“…Together, these results reveal that the induction of, and emergence from, dexmedetomidine-induced unconsciousness involve widespread, coordinated changes in brain connectivity and neurovascular function; across our findings, we also highlight the recurrent role of cerebellum in conscious-unconscious transitions.…”
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No association between age-related hearing loss and brain age derived from structural neuroimaging data by Stephanie Rosemann, Christiane M. Thiel

“…Aging affects the brain's underlying biophysical structure as well as its cellular and molecular functioning. Brain aging varies largely across individuals and is increased in a variety of disease states. …”
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Spatial accessibility and equity of primary healthcare in Zhejiang, China by Rixiang Xu, Caiming Xu, Lang Wu, Xuefeng Xie, Tingyu Mu

“…The two-step floating catchment area (2SFCA) method, weighted by a Gaussian function, was employed to measure the SA of PHC institutions, general practitioners (GPs), and beds across various residential areas. …”
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Burden of cystic fibrosis in children by Kathryn Bresnick, Emilio Arteaga-Solis, Stefanie J Millar, Glen Laird, Cecile LeCamus

“…CF-related medication and nutritional supplementation use was common across all ages and genotypes. More than half (54.7%) had ≥1 CF-related complication. …”
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Seasonal discrepancy of airborne fungal diversity and community structure in Lentinula edodes factory by Wenbing Gong, Kaixiao Qiu, Zhen Zhuang, Lujun Zhang, Xueqing Liu, Xiao Yu, Yinbing Bian, Yang Xiao

“…The airborne fungal communities across distinct function areas showed convergence. …”
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