Functionally redundant Rho GTPases Cdc42 and RacA regulate aflatoxin synthesis and pathogenicity in Aspergillus flavus by controlling morphogenesis, oxidative balance and energy me... by Jia Xu, Junhe Ren, Yanyan Zhang, Zhuoyu Han, Qing Kong

“…Rho GTPases Cdc42 and RacA exhibit significant sequence homology and are conserved across eukaryotic species. These proteins function as molecular switches within various signal transduction pathways by cycling between GTP-bound (active) and GDP-bound (inactive) states. …”
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Effects of water‐soluble mangosteen extract on cognitive function and neuropsychiatric symptoms in patients with mild to moderate Alzheimer's disease (WECAN‐AD): A randomized contr... by Weerasak Muangpaisan, Puvanant Wiputhanuphongs, Nattapon Jaisupa, Sarawut Junnu, Jutima Samer, Primchanien Moongkarndi, Orawan Supapueng, Chalobol Chalermsri, Neelobol Neungton

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Analysis of consumer purchase intentions using functional near-infrared spectroscopy(fNIRS): A neuromarketing study on the aesthetic packaging of Korean red ginseng products. by SuJin Bak, Jaeyoung Shin, Daeun Kim, Sungkean Kim

“…<h4>Purpose</h4>This study investigates the consumer behavior patterns for Korean red ginseng products using functional near-infrared spectroscopy (fNIRS), a neuroimaging device. …”
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Assessment of vestibulo-ocular reflex function in people with Parkinson’s disease: a cross-sectional study in a rehabilitation setting using the video head impulse test by Nicola Ferri, Laura Casagrande Conti, Leonardo Manzari, Diego Piatti, Domenico De Angelis, Ugo Nocentini, Marco Tramontano

“…The video head impulse test was used to assess the VOR function across all six semicircular canals, using both the Head Impulse Paradigm (HIMP) and the Suppression Head Impulse Paradigm (SHIMP) paradigms. …”
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Evaluation of transcutaneous electrical acupoint stimulation for improving pain and cognitive function in elderly patients around the perioperative period of hip replacement surger... by Sujuan Xu, Kai Huang, Qing Jiang

“…Future studies should further investigate the optimal TEAS protocols to maximize these benefits across different population and surgical settings.…”
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Efficacy of Spiritual-Religious Interventions on Clinical and Functional Outcomes in Iranian Adults with Mental Disorders/Negative Psychological Symptoms: A Systematic Review of Ra... by Hassan Farrahi, Fataneh Bakhshi, Hadi Basiri, Fatemeh Amini Khodashahri, Zeynab Haghdoost

“…Materials and Methods: A comprehensive search was conducted across Iranian and international scientific databases until 2022. …”
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Psychometric analysis of the patient-reported outcomes measurement information system parent proxy physical function–upper extremity item bank for children with Duchenne muscular d... by Linda Pax Lowes, Corinne M. Le Reun, Teofil Ciobanu, Lindsay N. Alfano, Natalie F. Reash, Megan A. Iammarino, Shivangi Patel, Ivana F. Audhya

“…A new customized 21-item measure demonstrated overall good fit to Rasch model expectations (p = 0.095; nonsignificant) and the ability to discriminate among respondents with different levels of upper extremity function (0.95 PSI; excellent reliability). Upper extremity function was generally well targeted across the severity spectrum, except for the least severe patients.ConclusionThe customized PROMIS PP UE measure conformed to Rasch assumptions, indicating that it can serve as a reliable option for caregiver-reported upper extremity assessment in DMD.…”
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Oral functions in adult persons with spinal muscular atrophy compared to a healthy control group: a prospective cross-sectional study with a multimodal approach by Teresa Kruse, Diana Leflerovà, Annette Cap, Sara Portegys, Brunhilde Wirth, Raoul Heller, Svenja Brakemeier, Tim Hagenacker, Bert Braumann, Gilbert Wunderlich

“…Conclusions The impairment of oral function varies across persons with SMA. Routine measurement of oral function is warranted to determine individual bulbar involvement stages. …”
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Construction of an Overexpression Library for Chinese Cabbage Orphan Genes in <i>Arabidopsis</i> and Functional Analysis of <i>BOLTING RESISTANCE 4</i>-Mediated Flowering Delay by Ruiqi Liao, Ruiqi Zhang, Xiaonan Li, Mingliang Jiang

“…Orphan genes (<i>OGs</i>), which are unique to a specific taxon and have no detectable sequence homology to any known genes across other species, play a pivotal role in governing species-specific phenotypic traits and adaptive evolution. …”
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Effects of whole-body vibration training as an adjunct to conventional rehabilitation exercise on pain, physical function and disability in knee osteoarthritis: A systematic review... by Yan Peng, Qi Qi, Chai Li Lee, Yan Ling Tay, Siaw Chui Chai, Mohd Azzuan Ahmad

“…<h4>Objective</h4>To elucidate the combined effects of WBVT and rehabilitation exercise on pain, physical function, and disability in KOA management through a systematic review and meta-analysis.…”
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Short-term oral zinc supplementation enhances Natural Killer cell functionality and decreases circulating Innate Lymphoid Cell counts and frequencies in healthy young adults by Lara Amling, Lothar Rink, Sabrina B. Bennstein

“…Conclusions Since proper NK cell functionality is required for early defense against infected or malignant cells, and cILCs act as progenitors to replenish tissue resident ILCs, which are crucial for tissue homeostasis and barrier integrity, our results suggest that routine zinc supplementation might be a simple yet effective strategy to enhance immune defense and potentially prevent diseases across different dietary groups. …”
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Modern fixation techniques versus traditional tension band wiring for olecranon fractures: a systematic review and meta-analysis of functional outcomes, healing time, and complicat... by Chengjing Wang, Changqing Li

“…This systematic review and meta-analysis evaluates the comparative effectiveness of these fixation methods in terms of functional outcomes, healing time, and complications. …”
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Emotion dysregulation and impulsivity as overlapping symptoms in adult Attention-Deficit/Hyperactivity Disorder and Borderline Personality Disorder: severity profiles and associati... by Eszter Kenézlői, Lívia Balogh, Szilvia Somogyi, Evelyn E. Lévay, Zsuzsa Halmai, Zsófia Nemoda, Zsolt S. Unoka, János M. Réthelyi

“…Higher levels of childhood trauma were associated with emotion dysregulation, trait impulsivity, and delay aversion across groups. Emotion regulatory capacity played a significant mediating role between childhood traumatization and the level of personality functioning. …”
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Neurodevelopmental, cognitive and motor function: Practice recommendations in pediatric intestinal failure and transplantation- position statement of the International Intestinal R... by Stephanie So, Catherine Patterson, Taru Palsa, Jemma Mears, Bianca C. Bondi, Sydney Dempster, Christina Belza

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Omija (Schisandra chinensis) extract and soybean mixture to enhance memory function through the gut-brain axis: network pharmacology and in vivo validation of multi-target mechanis... by Yu Yue, Hye Jeong Yang, Myung-Sunny Kim, Ting Zhang, Chen Li, Min Jung Kim, Dai-Ja Jang, Sunmin Park

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Characterization of MADS-Box Gene Family in <i>Isatis indigotica</i> and Functional Study of <i>IiAP1</i> in Regulating Floral Transition and Formation by Yanqin Ma, Yanhong Lan, Ju Li, Haicheng Long, Yujie Zhou, Zhi Li, Mingjun Miao, Jian Zhong, Haie Wang, Wei Chang, Ziqin Xu, Liang Yang

“…We then selected <i>IiAP1</i> for functional studies and found that it is localized to the nucleus and highly expressed in inflorescence, sepals, and petals. …”
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The Role of Coenzyme Q10 in Modern Medicine: Insights into Energy Metabolism and Antioxidant Therapy by Mateusz Górski, Adrianna Załęska, Mateusz Bychowski, Julia Kwaśna, Izabela Kaźmierczyk, Kacper Lenart, Michał Homza, Natalia Zakrzewska, Szymon Bednarek, Joanna Kulicka

“…However, gaps remain in understanding its optimal dosing, long-term impact, and efficacy across diverse health conditions.     Methods: This review synthesized findings from clinical trials, meta-analyses, and observational studies. …”
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Race-neutral versus race-specific GLI reference equations on spirometry interpretation in the general population by Joon Young Choi, Chin Kook Rhee, Yong Suk Jo, Yet Hong Khor

“…Caution is needed when switching pulmonary function interpretation approaches, in particular the differential effects across race and ethnicity.…”
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Impact of Fecal Microbiota Transplant Formulations, Storage Conditions, and Duration on Bacterial Viability, Functionality, and Clinical Outcomes in Patients with Recurrent <i>Clos... by Mohamed Shaheen, Chelsea McDougall, Leona Chan, Rose Franz, Karen Wong, Ryland T. Giebelhaus, Gwen Nguyen, Seo Lin Nam, A. Paulina de la Mata, Sam Yeo, James J. Harynuk, Sepideh Pakpour, Huiping Xu, Dina Kao

“…However, the impact of FMT formulations and storage conditions on bacterial viability, community structure, functionality, and clinical efficacy remains under-investigated. …”
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Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions by Martin Škandík, Lara Friess, Guillermo Vázquez-Cabrera, Lily Keane, Kathleen Grabert, Mireia Cruz De los Santos, Mercedes Posada-Pérez, Austeja Baleviciute, Mathilde Cheray, Bertrand Joseph

“…Abstract The aging process is marked by a time-dependent deterioration in cellular functions, particularly the immune and neural systems. …”
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