Improving the shelf-life and functionality of an orange juice by the addition of polyphenol-enriched extracts obtained using natural deep eutectic solvents by Clara Gomez-Urios, Lorenzo Siroli, Davide Gottardi, Simona Benedetti, Rosalba Lanciotti, Ana Frigola, Susanna Buratti, Jesus Blesa, Mattia Di Nunzio, Francesca Patrignani, Maria J Esteve

“…Overall, this study demonstrates the feasibility of extending the shelf life and enhancing the functionality of orange juice using NADES extracts and without compromising its organoleptic properties.…”
Get full text

Acute Lateral Ankle Sprain Impairs Function and Strength Without Altering Muscle or Tendon Stiffness: A Controlled Observational Study by Pedro Bainy Franz, José Roberto deSouza Júnior, Hortência Cordeiro deLima, Estevão deSouza Diniz, Rogério deBrito Aguiar, Jeam Marcel Geremia, Henrique Mansur, Rita deCássia Marqueti, João Luiz Quagliotti Durigan

“…ABSTRACT Introduction Acute lateral ankle sprain (LAS) frequently results in persistent functional limitations. Understanding changes in calf muscle and Achilles tendon (AT) stiffness after LAS may shed light on mechanisms underlying impaired function. …”
Get full text

The sucrose synthase gene family in blueberry (Vaccinium darrowii): functional insights into the role of VdSUS4 in salt stress tolerance by Yanwen Wang, Yanwen Wang, Yanwen Wang, Lei Yang, Lei Yang, Lei Yang, Lei Yang, Lei Yang, Wenzhu Geng, Wenzhu Geng, Wenzhu Geng, Hongxia Zhang, Hongxia Zhang, Hongxia Zhang, Hongxia Zhang, Hongxia Zhang, Houjun Zhou, Houjun Zhou, Houjun Zhou, Houjun Zhou, Houjun Zhou

“…Our analysis encompassed the physicochemical properties, gene structures, conserved motifs, promoter cis-acting elements, chromosomal locations, evolutionary relationships and expression profiles of these family members, allowing us to predict their potential functions. ResultsWe identified seven distinct SUS genes, mapped across six chromosomes, showcasing the complexity of this gene family in blueberries. …”
Get full text

The effectiveness of modified constraint-induced movement therapy on upper limb function in children with cerebral palsy: a systematic review and meta-analysis by Haiyan Wang, Jilan Zhou, Xiaojing Shan, Li Zhang

“…This study aimed to evaluate the therapeutic impact of m-CIMT on upper limb function in children with CP. Methods A systematic search was performed across six electronic databases—China National Knowledge Infrastructure (CNKI), Wanfang, PubMed, Web of Science, the Cochrane Library, and Embase—from their inception to May 6, 2025. …”
Get full text

UVB radiation and amphibian resilience: Analyzing skin color, immune suppression and oxidative stress in Rana kukunoris from different elevations by Xiaolong Tang, Juan Wu, Haoqi Zhang, Liye Zhong, Rui Su, Ming Ma, Huihui Wang, Miaojun Ma, Qiang Chen

“…These findings reveal distinct physiological strategies within the same species for coping with UVBR across altitudinal gradients. Amid global increases in UVBR, this study offers novel insights into amphibian resilience in high-UVBR habitats and informs conservation strategies for populations across varying elevations.…”
Get full text

Causal associations between liver function biomarkers and prostate cancer risk in European and East Asian populations: a univariate, multivariable, and bidirectional Mendelian Rand... by Xinyu Xu, Wenjing Zhu, Yu Peng

“…Additionally, genetic variations across populations may influence the direction and strength of this association. …”
Get full text

Factors influencing cognitive function in Chinese elderly individuals: The role of traditional Chinese medicine in a large-scale cross-sectional study by Houqin Li, Ran Chen, Jing Xia, Feiyu He, Yan Zhang, Shulan Tang, Cheng Ni

“…Methods: We used cross-sectional data from seven geographical regions across mainland China. The Changsha version of the Montreal Cognitive Assessment was used to assess cognitive function. …”
Get full text

Identification and Estimation in Linear Models with Endogeneity Through Time-Varying Volatility by Shih-Tang Hwu

“…This paper proposes a novel control function approach to identify and estimate linear models with endogenous variables in the absence of valid instrumental variables. …”
Get full text

Expression levels of T cell-related immune factors and their correlation with thyroid function in Graves’ disease with varied serum iodine status: insights into immunopathogenesis... by Lilan Wang, Zixuan Ru, Shengnan Gao, Na Lv, Kerou Li, Hong Qiao

“…ObjectiveMeasurement of Serum Iodine Concentration (SIC) in Newly Diagnosed Adult Graves’ Disease (GD) Patients with Hyperthyroidism and Healthy Controls: Investigating Cytokine Expression Profiles and Their Correlations with Thyroid Function Across Diverse Iodine Nutritional Status.MethodPatients newly diagnosed with GD hyperthyroidism from September 2024 to February 2025 at our institution were enrolled. …”
Get full text

Antimicrobial efficacy of methylene blue-functionalized graphene oxide-mediated photodynamic therapy against Enterococcus faecalis in root canal disinfection by Rizwan Jouhar, FCPS, Mohamad S. Halim, M.Res.Dent, Sayed A. Quadri, MD, Muhammad A. Ahmed, PhD, Faheem Shah, PhD

“…Abstract: Objective: This study assessed the antimicrobial efficacy of photodynamic therapy (PDT) using functionalized graphene oxide with methylene blue (MB/rGO) to achieve root canal disinfection against Enterococcus faecalis. …”
Get full text

Odor induced functional connectivity alteration of POC-anterior frontal cortex-medial temporal cortex in patients with mild cognitive impairment by Weiping Li, Jianan Zhou, Shuying Li, Min Wu, Yajing Zhu, Qian Chen, Futao Chen, Xuefeng Ma, Xin Zhang, Zhengge Wang, Jiaming Lu, Bing Zhang, Bing Zhang, Bing Zhang, Bing Zhang, Bing Zhang, Bing Zhang, Bing Zhang

“…All subjects underwent cognitive assessments, olfactory behavior tests, and odor-based functional magnetic resonance imaging (fMRI). Differences in FC within olfactory circuits were analyzed using the generalized psychophysiological interaction (gPPI) method.ResultsMild cognitive impairment patients showed significant cognitive deficits, including lower scores on the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA), alongside impairments in episodic memory, visuospatial memory, executive function, language, attention, olfactory threshold, and total olfactory function. …”
Get full text

Brain endurance training as a strategy for reducing mental fatigue by Nathalie André, Michel Audiffren, Chris Englert

“…It impairs sports performance across various disciplines. Individual differences in mental fatiguability and physical fitness may moderate the effects of mental fatigue. …”
Get full text

The Spanish version of the Level of Personality Functioning Scale – Brief Form 2.0 (LPFS-BF 2.0): Psychometric evaluation in adolescents who have suffered from parental abuse and n... by Balzen Kennedy M., Sharp Carla, Unzurruzaga Erne, Eguren Ane, Pérez Luis

“…Level of Personality Functioning (LPF) is particularly relevant for the identification of emerging personality dysfunction in adolescents given its ability to capture developmental discontinuity as metacognitive capacities in self- and interpersonal-functioning emerge. …”
Get full text

Serum metabolic fingerprints encode functional biomarkers for ovarian cancer diagnosis: a large-scale cohort studyResearch in context by Wanshan Liu, Xiaoxiao Hu, Zhouzhou Bao, Yanyan Li, Juxiang Zhang, Shouzhi Yang, Yida Huang, Ruimin Wang, Jiao Wu, Xiaoyu Xu, Qi Sang, Wen Di, Huaiwu Lu, Xia Yin, Kun Qian

“…Methods: We constructed a large-scale OC-associated cohort of 1432 subjects, including 662 OC, 563 benign ovarian disease, and 207 healthy control subjects, across retrospective (n = 1073) and set-aside validation (n = 359) cohorts. …”
Get full text

Antimicrobial efficacy of methylene blue-functionalized graphene oxide-mediated photodynamic therapy against Enterococcus faecalis in root canal disinfection by Rizwan Jouhar, FCPS, Mohamad Syahrizal Halim, M.Rest.Dent, Sayed A. Quadri, MD, Muhammad Adeel Ahmed, PhD, Faheem Shah, PhD

“…Abstract: Objective: This study assessed the antimicrobial efficacy of photodynamic therapy (PDT) using functionalized graphene oxide with methylene blue (MB/rGO) to achieve root canal disinfection against Enterococcus faecalis. …”
Get full text

Identification and functional characterization of T-cell exhaustion-associated lncRNA AL031775.1 in osteosarcoma: a novel therapeutic target by Yameng Wang, Yameng Wang, Yameng Wang, Yameng Wang, Jinghong Yuan, Jinghong Yuan, Jinghong Yuan, Keying Guo, Keying Guo, Keying Guo, Zhuoer Zhang, Junchao Zhu, Junchao Zhu, Junchao Zhu, Shahrzad Arya, Guowen Huang, Guowen Huang, Guowen Huang, Shengqin Li, Shengqin Li, Shengqin Li, Qi Chen, Xijuan Liu, Jingyu Jia, Jingyu Jia, Jingyu Jia

“…A six-lncRNA prognostic model was established using LASSO regression and validated in separate cohorts. Functional assays evaluated the impact of the lncRNA AL031775.1 on osteosarcoma cell behavior and T-cell function.ResultsTwenty-four key T-cell exhaustion-related genes were identified and significantly enriched in immune-related pathways, indicating their importance in the osteosarcoma immune microenvironment. …”
Get full text

Tell me why: A scoping review on the fundamental building blocks of fMRI-based network analysis by Z. van der Pal, L. Douw, A. Genis, D. van den Bergh, M. Marsman, A. Schrantee, T.F. Blanken

“…This review explores the current landscape of network estimation methods in the context of functional MRI (fMRI) based network neuroscience, focusing on static undirected network analysis. …”
Get full text

Review on atomistic and quantum mechanical simulation approaches in chemical mechanical planarization by Seokgyu Ryu, Murali Ramu, Patrick Joohyun Kim, Junghyun Choi, Kangchun Lee, Jihoon Seo

“…Significant progress has been achieved using Fukui function analysis for additive screening, density functional theory (DFT) for surface passivation mechanisms, and molecular dynamics (MD) simulations for CMP processes. …”
Get full text

Genomic, transcriptomic and epigenomic signatures of ageing and cold adaptation in the Antarctic clam Laternula elliptica by Victoria A. Sleight, Melody S. Clark, Meghan K. Yap-Chiongco, Frances Turner, Kevin M. Kocot

Get full text

Sparse Adaptive Optimization Based on Low Rank Decomposition for Image Defect Detection by Daihong Jiang, Zhixiang Chen, Sanyou Zhang, Yunfei Li, Lu Zhao

Get full text