Genetic inactivation of zinc transporter SLC39A5 improves liver function and hyperglycemia in obesogenic settings by Shek Man Chim, Kristen Howell, John Dronzek, Weizhen Wu, Cristopher Van Hout, Manuel AR Ferreira, Bin Ye, Alexander Li, Susannah Brydges, Vinayagam Arunachalam, Anthony Marcketta, Adam E Locke, Jonas Bovijn, Niek Verweij, Tanima De, Luca Lotta, Lyndon Mitnaul, Michelle LeBlanc, Regeneron Genetics Center, David J Carey, Olle Melander, Alan Shuldiner, Katia Karalis, Aris N Economides, Harikiran Nistala, DiscovEHR collaboration, Regeneron Genetics Center

“…Moreover, rare loss-of-function variants in the zinc efflux transporter SLC30A8 reduce T2D risk. …”
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Multimodal Fusion Framework for Urban functional zone change detection using Remote Sensing and Social Sensing Data by B. Fang, B. Fang, B. Fang, B. Fang, X. Chen, X. Chen, X. Chen, X. Chen, H. Chen, H. Chen, Z. Xiang, Z. Xiang, B. Hu, B. Hu, Z. Hu, Z. Hu, Z. Hu, Z. Hu, W. Tu, W. Tu, W. Tu, W. Tu

“…For the RS-branch, RS imagery provides detailed spatial information about urban transformations; for the MP-branch, MP data as a typical social sensing data captures temporal patterns in human mobility, offering insights into functional shifts in urban spaces. By fusing these two complementary modalities, our approach allows for a more nuanced detection of urban functional zone changes. …”
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Investigating POU3F4 in cancer: Expression patterns, prognostic implications, and functional roles in tumor immunity by Weiwei Chen, Yaya Ji, Rui Wang, Ruijie Ji, Yujian Lin, Yuhang Wu, Lehan Liu, Tianle Sha, Wen Li, Lei Zhang, Longfei Yang, Xinhua Zhang, Jianxiang Song

“…This study aims to assess the prognostic value of POU3F4 in thirty-three cancers and explore its immune-related functions. Based on data from The Cancer Genome Atlas (TCGA), Cancer Cell Line Encyclopedia (CCLE), Genotype-Tissue Expression (GTE), and Gene Set Cancer Analysis (GSCA), we employed various bioinformatics approaches to investigate the potential carcinogenic effects of POU3F4. …”
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Perioperative, Oncological, and Functional Outcomes of New Multiport Robotic Platforms in Urology: A Systematic Review and Meta-analysis by Giuseppe Reitano, Arianna Tumminello, Umar Ghaffar, Giorgio Saggionetto, Alessandra Taverna, Francesco Mangiacavallo, Mohamed E. Ahmed, Spyridon P. Basourakos, Filippo Carletti, Davide Minardi, Massimo Iafrate, Alessandro Morlacco, Giovanni Betto, R. Jeffrey Karnes, Fabrizio Dal Moro, Fabio Zattoni, Giacomo Novara

“…Conclusions and clinical implications: When compared with the DVM-SR, NM-SRs may offer similar safety, and oncological and functional outcomes across most surgeries for both benign and malignant diseases. …”
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Longitudinal Assessment of Structural and Functional Changes in Rod-cone Dystrophy: A 10-year Follow-up Study by Alexis Ceecee Britten-Jones, BOptom (Hons), PhD, Chi D. Luu, BOrth (Hons), PhD, Jasleen K. Jolly, MSc, DPhil, Carla J. Abbott, BOptom, PhD, Penelope J. Allen, MBBS, FRANZCO, Tina Lamey, PhD, Terri McLaren, BSc, Jennifer A. Thompson, PhD, John De Roach, PhD, Thomas L. Edwards, PhD, FRANZCO, Lauren N. Ayton, BOptom, PhD

“…This longitudinal study investigated the genetic diagnosis and change in retinal structure and function over 10 years in rod-cone dystrophies (RCDs). …”
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PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP by Jiongke Wang, Yujie Shi, Ying Wang, Yingqiang Shen, Huan Liu, Silu Sun, Yimei Wang, Xikun Zhou, Yu Zhou, Xin Zeng, Jing Li, Qianming Chen

“…This interaction is dependent on the C1QBP N-terminus (aa 1–167) rather than the known functional domain. Point mutation in C1QBP (T76A/G78N) disrupting predicted hydrogen bonding with PA28γ-D177 significantly reduced their binding. …”
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A Modified Model Dielectric Function for Analyzing Optical Spectra of InGaN Nanofilms on Sapphire Substrates by Devki N. Talwar, Hao-Hsiung Lin, Jason T. Haraldsen

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Impedance Spectroscopy Study of Charge Transfer in the Bulk and Across the Interface in Networked SnO₂/Ga₂O₃ Core–Shell Nanobelts in Ambient Air by Maciej Krawczyk, Ryszard Korbutowicz, Patrycja Suchorska-Woźniak

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Intrinsic brain mapping of cognitive abilities: A multiple-dataset study on intelligence and its components by Simone Di Plinio, Mauro Gianni Perrucci, Grazia Ferrara, Maria Rita Sergi, Marco Tommasi, Mariavittoria Martino, Aristide Saggino, Sjoerd JH Ebisch

“…Our findings reveal consistent brain-behavior relationships across the datasets. Nodal efficiency in fronto-parietal sensorimotor regions consistently played a pivotal role in fluid reasoning, whereas efficiency in visual networks was linked to executive functions and memory. …”
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The Effects of Exercise Intervention in Older Adults With and Without Sarcopenia: A Systematic Review by Jeremy Cabrolier-Molina, Alexandra Martín-Rodríguez, Vicente Javier Clemente-Suárez

“…This systematic review, conducted in accordance with PRISMA guidelines and registered in PROSPERO (CRD42024619693), aimed to evaluate the effects of physical exercise interventions on muscle function and fall risk in older adults with and without sarcopenia. …”
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Vagus nerve stimulation as a predictive coding modulator that enhances feedforward over feedback transmission by Shinichi Kumagai, Shinichi Kumagai, Tomoyo Isoguchi Shiramatsu, Kensuke Kawai, Hirokazu Takahashi

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Sparse connectivity enables efficient information processing in cortex-like artificial neural networks by Rieke Fruengel, Rieke Fruengel, Marcel Oberlaender, Marcel Oberlaender

“…We explore the origins of these surprising findings and show that conventional dense ANNs distribute information across only a very small fraction of nodes, whereas sparse ANNs distribute information across more nodes. …”
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Disrupted HIV care during COVID-19 pandemic associated with increased disabilities among people living with HIV in Belize by Tracy M. Quetzal, Wei-Cheng Lo, Ya-Wen Chiu, Hung-Yi Chiou

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Modelling severe weather impact on traffic mobility and evaluating cross-regional applicability to functionally distinct segments in cold region highway networks by Hyuk-Jae Roh

“…Overall, the study highlights the feasibility of improving winter traffic models and their applicability across diverse road segments, benefiting transportation planning and management in cold climates.…”
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Acute effects of short-term high-intensity interval exercise and moderate-intensity aerobic exercise on food-related inhibitory control in obese adults: a randomized controlled cro... by Bo Sun, Bo Sun, Yun-Fei Lu, Ji-Wei Chen, Yi-Lun Xiao, Jie Ren

“…This study aimed to examine the acute effects of short-term high-intensity interval exercise (HIIE) and moderate-intensity aerobic exercise (MIAE) on food-related inhibitory function in obese adults, and to assess whether sex differences modulate the response to exercise interventions. …”
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Using Ecological Momentary Assessment to Assess Family Functioning in Spanish-Speaking Parent and Adolescent Dyads: Daily Questionnaire Study by Alejandra Fernandez, Savannah Bernal, Lana Kim, Subodh Potla

“…The variance across adolescents (SD 0.459) was larger than that within their individual reports of family functioning (SD 0.122). …”
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Comprehensive study on the impact of tea (<i>Camellia sinensis</i>) on human mental health by Quoc Dang Quan, Tuan Loc Le, Tran Minh Ly Nguyen, Thanh Cong Nguyen, My Ngoc Bui, Hoang Dung Tran

“… Tea, particularly the green, black, and oolong varieties derived from the Camellia sinensis plant, is widely consumed across the globe and has been associated with neuroprotective effects in human studies. …”
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A seated virtual exercise program to improve cardiovascular function in adults with chronic neurological impairments: a randomized controlled trial by Devina S. Kumar, Devina S. Kumar, Amy Bialek, Ayushi A. Divecha, Rachel M. Garn, Lydia E. J. Currie, Kathleen M. Friel, Kathleen M. Friel

“…Primary outcomes including Heart Rate (HR) Recovery (HRR), HR at Rest (HR Rest) and HR at peak exercise (HR Max) were averaged across three sessions at baseline, mid-study, and end of study. …”
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ForBac: A Static Analysis Approach With Forward and Backward Analysis for Precision in Floating-Point Computations by M. G. Thushara, K. Somasundaram

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The Role of Nutritional Supplementation in Hypothyroidism: A Review by Jakub Chodkowski

“…Materials and Methods: Comprehensive literature review was conducted across databases, including PubMed and Google Scholar for studies published between 2000 and 2023. …”
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