Efficacy of elongated needles for motor and balance function after a stroke: a systematic review and meta-analysis by Shuyan Zhang, Haichun Zhou

“…In terms of safety, the overwhelming majority of the studies included in the analysis reported the absence of adverse reactions.ConclusionEvidence from current studies indicates that elongated needle may improve post-stroke patients' balance and motor function, and enhance their daily living skills. However, the number of rigorous scientific studies is limited, and there is considerable variability across studies, limiting the confidence in these findings. …”
Get full text

Characterizing the effects of age, puberty, and sex on variability in resting-state functional connectivity in late childhood and early adolescence by Kelly A. Duffy, Andrea Wiglesworth, Donovan J. Roediger, Ellery Island, Bryon A. Mueller, Monica Luciana, Bonnie Klimes-Dougan, Kathryn R. Cullen, Mark B. Fiecas

“…Previous research has investigated how these factors relate to static (time-averaged) functional connectivity (FC), but little is known about their relationship with dynamic (time-varying) FC. …”
Get full text

CEA-Functionalized Gold Nanoparticles as a Nanovaccine Platform: In Vitro Evaluation of Cytocompatibility, Cellular Uptake, and Antigen Processing by Razvan-Septimiu Zdrehus, Teodora Mocan, Lavinia Ioana Sabau, Cristian Tudor Matea, Flaviu Tăbăran, Teodora Pop, Cristian Delcea, Ofelia Mosteanu, Lucian Mocan

“…This study aimed to evaluate the in vitro cytocompatibility, cellular uptake and antigen processing of carcinoembryonic antigen (CEA)-functionalized AuNPs as a nanovaccine candidate. <b>Materials and Methods.…”
Get full text

Functionalized magnetite-biochar with live and dead bacteria for adsorption-biosorption of highly toxic metals: Cd, Hg, and Pb by Yudha Gusti Wibowo, Dedy Anwar, Hana Safitri, Indra Surya, Sudibyo Sudibyo, Ahmad Tawfiequrrahman Yuliansyah, Himawan Tri Bayu Murti Petrus

“…Key findings include the composite's ability to function effectively across a broad range of environmental conditions and its potential for regeneration and reuse, highlighting its suitability for scalable applications. …”
Get full text

The characteristic structural and functional dynamics of P. falciparum DHFR binding with pyrimidine chemotypes implicate malaria therapy design by Wande M. Oluyemi, Goodness Nwokebu, Adeniyi T. Adewumi, Shadrach C. Eze, Chinedu C. Mbachu, Emmanuel C. Ogueli, Ngozi Nwodo, Mahmoud E.S. Soliman, Salerwe Mosebi

Get full text

Patterns of Functional Diversity, Species Diversity, and Endemicity Driven by Elevation and Topographic Complexity in a Mediterranean Mountain Refuge by Candan Aykurt, Kürşad Özkan, Mertcan Gülben, Özdemir Şentürk, Emirhan Berberoğlu, Semra Türkan, Zeynep Öz, Ramazan Süleyman Göktürk, Hasan Akgül, Sinem Günaydın, Muhammet Murat Görgöz

“…ABSTRACT This study investigates the variation in functional diversity (FD), species diversity (SD), and endemicity across all Mediterranean‐type vegetation belts (MVB) within a topographically complex mountainous refuge, focusing on their relationships with topographic and climatic factors. …”
Get full text

Association between Cystatin C and MRI Measures of Left Ventricular Structure and Function: Multi-Ethnic Study of Atherosclerosis by Subhashish Agarwal, Vinay Thohan, Michael G. Shlipak, Joao Lima, David A. Bluemke, David Siscovick, Antoinette Gomes, David M. Herrington

“…Introduction. Reduced kidney function, approximated by elevated cystatin C, is associated with diastolic dysfunction, heart failure, and cardiovascular mortality; however, the precise mechanism(s) that account for these relationships remains unclear. …”
Get full text

Tuberculosis parenteral therapeutic regimens for critical patients or non-functional intestinal tract: Brief review and proposal of protocol by Antonio Camargo Martins, Márcia Teixeira Garcia, Mariângela Ribeiro Resende

“…This strategy unifies practice across diverse clinical settings.…”
Get full text

A Priestia megaterium MF3 with high-efficiency zearalenone degradation: functional genomic insights and mechanistic exploration by Di Meng, Kai-Zhong Xu, Kai-Zhong Xu, Hong-Jian Hou, Jin-Bin Liu, Dan-Dan Deng, Jun-Min Li, Ya-Kun Fang, Xiao-Qin Zhu, Dong-Li Pei

Get full text

Comparing functional state of retina, macula, and optic nerve in preterm children and full-term children at school age by Mai A. Mohammed, Amr M. Elhady

“…Conclusion There were statistically significant differences in retinal, macular, and optic nerve functions between preterm children and full-term children at school age across many parameters associated with visual function, as determined by electrophysiological testing. …”
Get full text

Machine Learning for Predicting Postoperative Functional Disability and Mortality Among Older Patients With Cancer: Retrospective Cohort Study by Yuki Hashimoto, Norihiko Inoue, Takuaki Tani, Shinobu Imai

“…Currently, no model directly predicts postoperative functional disability in this population. …”
Get full text

Situating the salience and parietal memory networks in the context of multiple parallel distributed networks using precision functional mapping by Young Hye Kwon, Joseph J. Salvo, Nathan L. Anderson, Donnisa Edmonds, Ania M. Holubecki, Maya Lakshman, Kwangsun Yoo, B.T. Thomas Yeo, Kendrick Kay, Caterina Gratton, Rodrigo M. Braga

“…Summary: Brain networks serving higher cognitive functions are widely distributed across frontal and posterior association zones. …”
Get full text

Association of Circulating Neprilysin with BMI, Cardiovascular Health, and Kidney Function in High-Risk Pregnancies: A Pilot Study by Kaltrina Kutllovci Hasani, Azra Kulovic-Sissawo, Adam Saloň, Christina Stern, Karoline Mayer-Pickel, Mila Cervar-Zivkovic, Nandu Goswami, Herbert Fluhr, Ursula Hiden

“…Methods: Observed parameters were analyzed in 29 high-risk pregnant women across early, mid-, and late pregnancy. sNEP levels were analyzed alongside body mass index (BMI), endothelial dysfunction (ADMA), arterial stiffness (pulse wave velocity, PWV), retinal microvasculature (central retinal arteriolar and venular equivalents, CRAE and CRVE), and kidney function markers. …”
Get full text

Bridging Science and Lifestyle: A Feasibility Study for Developing a Novel Functional Food to Support Well-Being by Efstratios Christodoulou, Sotiria Laoutari, Fani Athanasiou, Eleni Poutli, Demetriana Andreou, Yiannis Kourkoutas, Antonios E. Koutelidakis

“…Additionally, this study lays the groundwork for a clinical trial exploring the effects of a novel functional food on mental health and well-being. Data were collected through an online bilingual survey (Greek/English) from 362 participants across Greece and Cyprus, using an adapted Functional Food Frequency Questionnaire (FFFQ) featuring 30 foods with documented effects on cognitive function and mood regulation. …”
Get full text

Growth maturity stage defines nutritional, anti-nutrients and functional food aspects of Moringa oleifera Lam. leaves by Saima Perveen, Saeed Akhtar, Dur-e-shahwar Sattar, Muhammad Qamar, Wisha Saeed, Mavra Amin, Tariq Ismail

Get full text

Integrated bioinformatics and functional studies identify CDK9 as a potential prognostic biomarker and therapeutic target in AML by Zhibin Xie, Yang Xia, Zhongyu Li, Mengmeng Zhang, Yuanyuan Tan, Yuqing Han, Meng Wang, Pingping Zhang, Jiajia Li

“…Results Bioinformatics analysis revealed significantly elevated CDK9 expression in AML samples, which correlated with poor patient prognosis. Functional enrichment analysis indicated that CDK9 is involved in key pathways related to cell proliferation, differentiation, and the tumor microenvironment. …”
Get full text

Elevational adaptation and distribution of woody saplings in a mountain forest: Insights from functional traits and mycorrhizal associations by Zuhua Wang, Xia Cai, Min Liu, Haibo Li, Jiayan Jiang, Jugang Wang, Fagen Qiu

Get full text

Exposure of Bisphenols (BPs) to hepatocellular carcinoma (HCC) patients and non-HCC patients: Association with liver function biomarkers by Shibo Li, Yanjie Li, Yun Deng, Fei Wang, Da Chen, Bin Lu, Nan Lin

“…Additionally, it analyzed the relationship between BPs and three liver function biomarkers: γ-glutamyl transferase (GGT), alanine aminotransferase (ALT) and alpha-fetoprotein (AFP). …”
Get full text

Sex-Dependent Rhizosphere Microbial Dynamics and Function in <i>Idesia polycarpa</i> through Floral and Fruit Development by Zhi Li, Qiupeng Yuan, Shasha Wang, Tao Zhang, Yanmei Wang, Qifei Cai, Xiaodong Geng, Yi Yang, Chao Miao, Li Dai, Sohel Rana, Zhen Liu

“…A significant correlation was observed between pH and AK and rhizosphere bacteria (<i>p</i> < 0.05), with metabolism being the main functional difference. This study provides preliminary insights into the functional predictions and analyses of bacteria associated with <i>Idesia polycarpa</i>. …”
Get full text

Engineered human B cells targeting tumor-associated antigens exhibit antigen presentation and antibody-mediated functions by Alexander Boucher, Courtney Anderson, Rochelle Hinman, Molly Kindschuh, Jeremy Fung, Tiansu Wang, Isabella Klooster, Elise Kim, Caroline Roth, Michael Vander Oever, Bakhmala Khan, Natalie Zelikson, Yaron Vagima, Huseyin Saribasak, Lisa Santry, Leah Natasha Klapper, Shmuel Hess, Jill Mooney, Débora Rosa Bublik, Haley Laken, Adi Barzel, Philip Borden, Cherylene Plewa, Ana Maria Chadbourne, Devin Bridgen, Alessio D. Nahmad, Alessio D. Nahmad

“…Recent studies have linked endogenous anti-tumor B cell immunity to favorable prognosis across multiple malignancies. Here, we present functional validation of human B cells engineered to target tumor-associated membrane and intracellular antigens. …”
Get full text