Brain penetration of peripheral extracellular vesicles from Alzheimer's patients and induction of microglia activation by Hermine Counil, Rummenigge Oliveira Silva, Jean‐Michel Rabanel, Charlotte Zaouter, Mohamed Haddad, Mohamed Raâfet Ben Khedher, Davide Brambilla, Tamas Fülöp, Shunmoogum A. Patten, Charles Ramassamy

“…To further assess their in vivo transport across the BBB, pEVs were injected into the blood circulation of 2‐days post‐fertilization Tg(flk1:EGFP) zebrafish. …”
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Performance Improvement of TiO₂ Ultraviolet Photodetectors by Using Atomic Layer Deposited Al₂O₃ Passivation Layer by Yao-Tsung Yang, Shih-Chin Lin, Ching-Chiun Wang, Ying-Rong Ho, Jian-Zhi Chen, Jung-Jie Huang

“…Moreover, high-resolution transmission electron microscopy indicated that following the annealing treatment, Al, Ti, and O atoms diffused across the interface between the Al₂O₃ passivation layer and TiO₂ NRs, resulting in the binding of these atoms to form Al–Ti–O bonds. …”
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Population-scale cross-disorder atlas of the human prefrontal cortex at single-cell resolution by John F. Fullard, Prashant NM, Donghoon Lee, Deepika Mathur, Karen Therrien, Aram Hong, Clara Casey, Zhiping Shao, Marcela Alvia, Stathis Argyriou, Tereza Clarence, David Burstein, Sanan Venkatesh, Pavan K. Auluck, Lisa L. Barnes, David A. Bennett, Stefano Marenco, PsychAD Consortium, Kiran Girdhar, Vahram Haroutunian, Gabriel E. Hoffman, Georgios Voloudakis, Jaroslav Bendl, Panos Roussos

“…As a commitment to fostering collaborative research, we provide this valuable resource as an online repository, enabling widespread analyses across the scientific community.…”
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Characteristics of Soil Profile Greenhouse Gas Concentrations and Fluxes of Alpine Grassland as Affected by Livestock Grazing by Mingyuan Yin, Xiaopeng Gao, Yanyan Li, Yufeng Wu, Wennong Kuang, Fanjiang Zeng

“…In contrast, soil profile nitrous oxide (N₂O) concentration did not vary with depth, possibly resulting from the relatively low soil moisture in the semiarid grassland, which increased air diffusivity across the soil profile. Grassland soil acted as a source of N₂O and CO₂ production but as a sink for CH₄ uptake, which mainly attributed to the topsoil (0–5 cm for N₂O, and 0–15 cm for CO₂ and CH₄). …”
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Pleiotropy of cancer susceptibility variants on the risk of non-Hodgkin lymphoma: the PAGE consortium. by Unhee Lim, Jonathan M Kocarnik, William S Bush, Tara C Matise, Christian Caberto, Sungshim Lani Park, Christopher S Carlson, Ewa Deelman, David Duggan, Megan Fesinmeyer, Christopher A Haiman, Brian E Henderson, Lucia A Hindorff, Laurence N Kolonel, Ulrike Peters, Daniel O Stram, Maarit Tiirikainen, Lynne R Wilkens, Chunyuan Wu, Charles Kooperberg, Loïc Le Marchand

“…Study-specific results for each variant were meta-analyzed across studies.<h4>Results</h4>The analysis of NHL subtype-specific GWAS SNPs and overall NHL suggested a shared genetic susceptibility between FL and DLBCL, particularly involving variants in the major histocompatibility complex region (rs6457327 in 6p21.33: FL OR=1.29, p=0.013; DLBCL OR=1.23, p=0.013; NHL OR=1.22, p=5.9 × E-05). …”
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Forensic pathological and histopathological analysis of ischemic sudden cardiac deaths in Egypt by Nora Fawzy Fnon, Asmaa Fady Sharif, Sanaa A. Abdo, Hanan Hosney Hassan, Zahraa Khalifa Sobh

“…This study presents the first comprehensive autopsy-based analysis of ischemic SCD in Egypt, offering detailed forensic and histopathological insights across age groups, with particular focus on cases under 40 and those involving acute myocardial infarction (MI). …”
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Actinomycosis: Mimicking Malignancies in Multiple Anatomical Sites—A Three-Patient Case Series by John Fernando Montenegro, Vanessa Correa Forero, Yamil Liscano, Andres Grueso Pineda, Diana Marcela Bonilla Bonilla, Paola Andrea Ruiz Jimenez

“…<i>Background and Objectives:</i> Actinomycosis is a rare chronic contagion caused by <i>Actinomyces</i> spp. known for its ability to mimic malignant processes across various anatomical locations. Its clinical presentation can often resemble malignancies, <i>Mycobacterium tuberculosis</i> infections, nocardiosis, fungal infections, or other granulomatous diseases. …”
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Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma by Michael Heming, Svea Haessner, Jolien Wolbert, I-Na Lu, Xiaolin Li, Benjamin Brokinkel, Michael Müther, Markus Holling, Walter Stummer, Christian Thomas, Andreas Schulte-Mecklenbeck, Flavia de Faria, Marlon Stoeckius, Stephan Hailfinger, Georg Lenz, Kornelius Kerl, Heinz Wiendl, Gerd Meyer zu Hörste, Oliver M. Grauer

“…Abstract Background Primary central nervous system lymphoma (PCNSL) is a rare lymphoma of the central nervous system, usually of diffuse large B cell phenotype. Stereotactic biopsy followed by histopathology is the diagnostic standard. …”
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ELM‐Wet: Inclusion of a Wet‐Landunit With Sub‐Grid Representation of Eco‐Hydrological Patches and Hydrological Forcing Improves Methane Emission Estimations in the E3SM Land Model... by Theresia Yazbeck, Gil Bohrer, Madeline E. Scyphers, Justine E. C. Missik, Oleksandr Shchehlov, Eric J. Ward, Sergio L. Merino, Robert Bordelon, Diana Taj, Jorge A. Villa, Kelly Wrighton, Qing Zhu, William J. Riley

“…We modified the calculation of aerenchyma transport diffusivity based on observed conductance per leaf area for different vegetation types. …”
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Apparent soil electrical conductivity and gamma-ray spectrometry to map particle size fraction in micro-irrigated citrus orchards in California by Elia Scudiero, Elia Scudiero, Michael P. Schmidt, Todd H. Skaggs, Jorge F. S. Ferreira, Daniele Zaccaria, Alireza Pourreza, Dennis L. Corwin

“…We evaluated the use of soil apparent electrical conductivity (ECa) and gamma-ray spectrometry (GRS) to map particle size fraction across three micro-irrigated non-saline citrus orchards in California. …”
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Cooperation between coagulase and von willebrand factor binding protein in Staphylococcus aureus fibrin pseudocapsule formation by Dominique C.S. Evans, Amanda B. Khamas, Alex Payne-Dwyer, Adam J.M. Wollman, Kristian S. Rasmussen, Janne K. Klitgaard, Birgitte Kallipolitis, Mark C. Leake, Rikke L. Meyer

“…Coa localises to cell surfaces to produce a surface-attached fibrin pseudocapsule but can diffuse from cells to produce matrix-associated fibrin. vWbp produces matrix-associated fibrin in the absence of Coa, and furthermore accelerates pseudocapsule production when Coa is present. …”
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Self-assembled arginine-based eutectogel microneedles as novel transdermal delivery system for pigmentation treatment by Hui Ma, Yier Li, Qiufeng Yao, Ruixiu Qin, Yanan Wang, Wenhui Wu, Hui Luo, Qi Zhao, Hua Ye, Kefeng Wu

“…An efficient and patient-friendly strategy for administering skin pigmentation is achieved through microneedles (MNs) -mediated drug delivery into the dermal interstitium across the stratum corneum. In this work, we design a eutectogel to fabricate dissolving MNs delivery system, which were self-assembled from small molecules of arginine and sorbitol driven by hydrogen bonding interaction. …”
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Investigation of corrosion void formation in a Ni-based alloy under simulated MSW incineration condition by Xinxin Wu, Terrence Wenga, Wenchao Ma

“…The alloying elements had varied distribution patterns across the voids with Ni and W elements being immobile and mainly occurring in the base substrate while Cr and Al undergo selective removal and diffuse to the surface, leading to the formation of a porous Ni/W-enriched layer. …”
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Common gene variants in the tumor necrosis factor (TNF) and TNF receptor superfamilies and NF-kB transcription factors and non-Hodgkin lymphoma risk. by Sophia S Wang, Mark P Purdue, James R Cerhan, Tongzhang Zheng, Idan Menashe, Bruce K Armstrong, Qing Lan, Patricia Hartge, Anne Kricker, Yawei Zhang, Lindsay M Morton, Claire M Vajdic, Theodore R Holford, Richard K Severson, Andrew Grulich, Brian P Leaderer, Scott Davis, Wendy Cozen, Meredith Yeager, Stephen J Chanock, Nilanjan Chatterjee, Nathaniel Rothman

“…We confirmed the association between TNF/LTA on chromosome 6p21.3 with NHL and found the LTA rs2844484 SNP most significantly and specifically associated with the major subtype, diffuse large B-cell lymphoma (DLBCL) (p-trend = 0.001). …”
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Individual-level cortical morphological network analysis in idiopathic normal pressure hydrocephalus: diagnostic and prognostic insights by Yifeng Yang, Meijing Yan, Lianxi Sun, Xiao Liu, Xuhao Fang, Shihong Li, Guangwu Lin

“…Cortical morphological similarity network, which quantify synchronized morphological changes across brain regions, offer novel insights into inter-individual neuroanatomical variability. …”
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Uncertainty-Aware Deep Learning for Robust and Interpretable MI EEG Using Channel Dropout and LayerCAM Integration by Óscar Wladimir Gómez-Morales, Sofia Escalante-Escobar, Diego Fabian Collazos-Huertas, Andrés Marino Álvarez-Meza, German Castellanos-Dominguez

“…Furthermore, LayerCAM visualizations enhanced with MCD transformed diffuse spatial activation patterns into more focused and interpretable topographies, aligning more closely with known motor-related brain regions and thereby boosting both interpretability and classification reliability across varying subject performance levels. …”
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The relation between cerebral small vessel function and white matter microstructure in monogenic and sporadic small vessel disease - the ZOOM@SVDs study by Naomi Vlegels, Hilde van den Brink, Anna Kopczak, Tine Arts, Stanley D.T. Pham, Jeroen C.W. Siero, Benno Gesierich, Alberto De Luca, Marco Duering, Jaco J.M. Zwanenburg, Martin Dichgans, Geert Jan Biessels

“…In cerebral small vessel disease (cSVD), vascular dysfunction has been associated with cSVD-lesions across the brain. Here we further explore the relation between vascular dysfunction and cSVD-related brain injury. …”
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Electroencephalographic biomarkers of antibody-mediated autoimmune encephalitis by Lu Sun, Yaping Hu, Jingjing Yang, Lihong Chen, Ying Wang, Wei Liu, Jau-Shyong Hong, Yunhui Lv, Lin Yang, Ying Wang

“…Anti-NMDAR encephalitis was marked by abnormal background activity, including extreme delta brush, frontotemporal delta activity, diffuse or focal slow waves, with scattered and unfixed IEDs. …”
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Dermatoscopic Patterns in Mycosis Fungoides: Observations from a Case-Series Retrospective Analysis and a Review of the Literature by Corrado Zengarini, Federica Tugnoli, Alessio Natale, Martina Mussi, Giacomo Clarizio, Claudio Agostinelli, Elena Sabattini, Alberto Corrà, Bianca Maria Piraccini, Alessandro Pileri

“…The vessel distribution was diffuse (40%) or perifollicular (36.7%), with a predominant red (56.7%) or orange (40%) background. …”
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Expansion of white matter hyperintensities is associated with the glymphatic system dysfunction in cerebral small vessel disease by Bang Zeng, Peng Zeng, Yayun Xiang, Yuling Peng, Dan Luo, Binglan Li, Ying Chai, Dan Wang, Lisha Nie, Yongmei Li

“…The metrics of the glymphatic system included the index of diffusivity along the perivascular space (Analysis aLong the Perivascular Space [ALPS] index) and the fractional volume of free water (FW). …”
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