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1281
Effect of Aneurysmal Subarachnoid Hemorrhage on Word Generation
Published 2014-01-01“…These results support a “diffuse damage” hypothesis of aSAH, indicated by late phase phonemic fluency impairment. …”
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1282
The p3 peptides (Aβ17-40/42) rapidly form amyloid fibrils that cross-seed with full-length Aβ
Published 2025-02-01“…Abstract The p3 peptides, Aβ17-40/42, are a common alternative cleavage product of the amyloid precursor protein, and are found in diffuse amyloid deposits of Alzheimer’s and Down Syndrome brains. …”
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1283
A novel missense variant of HS6ST2 gene in Paganini-Miozzo syndrome with a rare neurodevelopmental and Endocrine phenotypes
Published 2025-07-01“…The amino acid where the mutation c.764C>A p.P255Q occurs is conserved across multiple species, specifically being proline in 13 species. …”
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1284
Alician Blue Staining in Histological Assessment of Acid Mucopolysaccharides in Salivary Gland Tumors: A Diagnostic Perspective
Published 2025-06-01“…This study aims to evaluate the utility of AB staining in identifying AMPs across benign and malignant salivary gland tumors, providing a novel diagnostic perspective. …”
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1285
Inter-Organelle Crosstalk in Oxidative Distress: A Unified TRPM2-NOX2 Mediated Vicious Cycle Involving Ca<sup>2+</sup>, Zn<sup>2+</sup>, and ROS Amplification
Published 2025-06-01“…This “circular domino effect” integrates signals generated across the plasma membrane (Ca<sup>2+</sup>), lysosomes (Zn<sup>2+</sup>), mitochondria (ROS) and nucleus (ADPR), leading to progressive organelle failure, cellular dysfunction, and ultimately cell death. …”
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1286
Precision Medicine in Hematologic Malignancies: Evolving Concepts and Clinical Applications
Published 2025-07-01“…We discuss major molecular targets and personalized strategies across hematologic malignancies: <i>FLT3</i> and <i>IDH1/2</i> in acute myeloid leukemia (AML); Philadelphia chromosome–positive and Ph-like subtypes in acute lymphoblastic leukemia (ALL); <i>BCR-ABL1</i> in chronic myeloid leukemia (CML); <i>TP53</i> and <i>IGHV</i> mutations in chronic lymphocytic leukemia (CLL); molecular subtypes and immune targets in diffuse large B-cell lymphoma (DLBCL) and other lymphomas; and B-cell maturation antigen (BCMA) in multiple myeloma. …”
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1287
Photon-counting CT in liver disease: applications and advances
Published 2025-04-01“…With its ability to acquire data across multiple energy bins, PCCT achieves true multi-energy spectral imaging. …”
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1288
Gaussian Q Function Approximation in Wireless Communication System’s Design: A Gradient-Based Optimization Approach
Published 2025-01-01“…The primary goal is to iteratively minimize the error or cost function, progressively refining local minima across successive iterations. The results strikingly highlight the exceptional accuracy of our proposed approach in approximating the Gaussian Q function, positioning it as a robust contender for real-world communication system’s design. …”
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1289
Detection of new drivers of frequent B-cell lymphoid neoplasms using an integrated analysis of whole genomes.
Published 2021-01-01“…In the meantime, the aggregation of diverse tumors in pan-cancer genomic studies has become a useful tool to detect new driver genes, while enabling the comparison of mutational patterns across tumors. Here we present an integrated analysis of 354 B-cell lymphoid disorders. 112 recurrently mutated genes were discovered, of which KMT2D, CREBBP, IGLL5 and BCL2 were the most frequent, and 31 genes were putative new drivers. …”
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1290
On Introduction to q1,q2-Linear Diophantine Fuzzy Sets and Their Applications
Published 2025-01-01“…The notion of parameter mappings is about creating and managing a structured relationship between parameters across different systems or processes. This concept is vital in ensuring that data remains consistent, correctly interpreted, and accurately transformed as it moves through different parts of a system or between different systems. …”
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1291
Chest CT in Pulmonary Fibrosis: A Narrative Review of Imaging Patterns and Their Prognostic Significance
Published 2025-06-01“…This narrative review explores key imaging patterns observable on chest CT and their prognostic implications across these major subtypes. We conducted a literature review of studies published between 2010 and 2025 using PubMed, Scopus, and Web of Science, focusing on CT features, subtype differentiation, prognostic imaging biomarkers, and recent innovations in radiomics and artificial intelligence (AI). …”
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1292
Genetic K-Means Clustering of Soil Gas Anomalies for High-Enthalpy Geothermal Prospecting: A Multivariate Approach from Southern Tenerife, Canary Islands
Published 2025-06-01“…In this study, we apply a multivariate clustering technique—genetic K-Means clustering (GKMC)—to a comprehensive soil gas dataset collected from 1050 sampling sites across the ~100 km<sup>2</sup> Garehagua mining license, located in the southern rift zone of Tenerife (Canary Islands). …”
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1293
Transitioning to a low-carbon economy: The impact of green finance policies in BRICS nations
Published 2025-09-01“…Key empirical findings reveal that: (1) green finance has a significant and positive impact on energy efficiency, with strong direct and indirect effects across provinces; (2) spatial autocorrelation exists in energy usage, indicating that policy impacts diffuse geographically; (3) the synergistic effect of internet development and environmental regulation enhances green finance effectiveness; (4) regional disparities show stronger green finance impacts in eastern and western China compared to central regions; and (5) robustness checks using SDM-Wij and 2SLS confirm the stability and reliability of results. …”
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1294
An evaluation of selinexor’s clinical trial portfolio: a cross-sectional study
Published 2025-05-01“…Selinexor is a drug that received accelerated approval as a new treatment for relapsed or refractory diffuse-large B-cell lymphoma and multiple myeloma. …”
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1295
Immunohistochemical profile and distribution of Non-Hodgkin and Hodgkin lymphoma - An experience in a medical college hospital in Tamil Nadu
Published 2020-01-01“…Context: The subtype distribution of non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL) shows distinct pattern across geographic regions. This study analyzes the subtype distribution of lymphomas based on the WHO 2017 Classification using immunohistochemistry (IHC) and also investigates the IHC profile of various lymphomas. …”
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1296
Short-term impact of low air pressure on plants' functional traits.
Published 2025-01-01“…Lower atmospheric pressure affects biologically relevant physical parameters such as gas partial pressure and concentration, leading to increased water vapor diffusivity and greater soil water content loss through evapotranspiration. …”
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1297
Comparative analysis of intestinal tumor segmentation in PET CT scans using organ based and whole body deep learning
Published 2025-02-01“…Both approaches were trained using diffuse large B cell (DLBCL) patients from a large multi-center clinical trial (NCT01287741). …”
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1298
Regional profiling reveals a distinct glioblastoma infiltrative margin proteome
Published 2025-07-01“…Here, we investigated the feasibility of diverse methodological approaches to describe abnormal protein signalling across distinct intra-tumour regions of primary glioblastoma tissue, including proliferative core, peripheral rim, and invasive margin. …”
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1299
Three Complementary Sampling Approaches Provide Comprehensive Characterization of Pesticide Contamination in Urban Stormwater
Published 2025-02-01“…We detected 82 pesticides across the three sampling matrices, with most detections occurring in o-DGT samplers. …”
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1300
Global surface eddy mixing ellipses: spatio-temporal variability and machine learning prediction
Published 2025-01-01“…Coarse-resolution climate models are sensitive to the specification of eddy diffusivity tensor. Mixing ellipses, derived from eddy diffusivity tensor, illustrate mixing geometry, i.e., the magnitude, anisotropy, and dominant direction of eddy mixing. …”
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