The predictive value of changes in 18F-FDG PET/CT cardiac uptake patterns and metabolic parameters for anthracycline based chemotherapy induced cardiac toxicity in lymphoma patient... by Runlong Lin, Aijuan Tian, Ying Wang, Xiaomei Wang, Xin Yuan, Jing Yu, Guihua Li, Wenli Xie

“…Analyzing changes in uptake patterns, the group displaying abnormal changes exhibited an increase in left atrial diameter and a decrease in left ventricular ejection fraction compared to the group with normal changes. …”
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Monomorphic sustained right ventricular outflow tract tachycardia in pregnancy with favorable outcomes: a case report by Gidion Edwin, Joshua Ezekiel, Baraka Alphonce, Kelvin Masava, John Meda

“…A 12-lead electrocardiogram showed multiple monomorphic sustained ventricular tachycardia with the left bundle branch block pattern suggestive of right ventricular outflow tract tachycardia. …”
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BERT-based network for intrusion detection system by Yong Yang, Xing Peng

“…By treating network traffic as a “language,” our approach resolves issues that traditional methods struggle with while being scalable and adaptable to various network environments and attack patterns.…”
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Heart Failure with Preserved Left Ventricular Ejection Fraction: A Complex Conundrum Simply Not Limited to Diastolic Dysfunction by Angel Lopez-Candales, Talal Asif, Khalid Sawalha, Nicholas B. Norgard

“…Over the last two decades, the changing paradigm of heart failure with preserved ejection fraction (HFpEF) has transformed our understanding not only of the pathophysiology of this clinical entity but also the diagnostic and therapeutic approaches aimed at treating this complex patient population. No longer HFpEF should be seen as simply left ventricular diastolic dysfunction but as a group of that in addition of having small and thick left ventricles with abnormal diastolic filling patterns as their main pathophysiologic abnormality; they also have whole host of different abnormalities. …”
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The Efficacy and Brain Network Mechanism of Acupuncture for Knee Osteoarthritis: A Study Protocol for Randomized Controlled Neuroimaging Trial by Sun YY, Wang ML, Zhao RH, Hao MY, Song S, Zhou Y, Zhang N

“…Therefore, this study uses KOA as the research vehicle, focuses on the abnormal connectivity patterns of brain functional networks, and integrates clinical pain assessments to thoroughly investigate the central mechanisms of acupuncture therapeutic effects on KOA.Patients and Methods: In this parallel, randomized, sham-controlled neuroimaging trial, 60 KOA patients will be randomly divided into the acupuncture group and sham acupuncture group in a 1:1 ratio, treated three times weekly for a total of 12 sessions. …”
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Deconvolution of serum cortisol levels by using compressed sensing. by Rose T Faghih, Munther A Dahleh, Gail K Adler, Elizabeth B Klerman, Emery N Brown

“…Identification of the amplitude and timing of pulsatile hormone release allows (i) quantifying of normal and abnormal secretion patterns towards the goal of understanding pathological neuroendocrine states, and (ii) potentially designing optimal approaches for treating hormonal disorders.…”
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Psychological stress dysfunction in women with premenstrual syndrome by Qing Liu, Yuhang Lin, Wenjuan Zhang

“…Despite its prevalence, the neural mechanisms underlying PMS—particularly those related to stress—are not fully understood.This review aims to explore the complex interactions between PMS and stress, with a focus on the hormonal pathways involved. We propose that abnormal stress coping styles and stress reactivity patterns, collectively referred to as stress dysfunction, are crucial factors influencing women's vulnerability to PMS. …”
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Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats by Yaoyao Zhu, Ge Lu, Weixin Li, Chenchen Su, Pengfei Du, Shuyou Wang, Li Yang, Huanfang Xu, Yigong Fang, Xiaojing Song

“…In addition, we investigated the ovarian functional changes post-ISF obstruction and evaluated the therapeutic effects of acupuncture on ovarian dysfunction in aged rats, both in unblocked and ISF-blockade conditions.ResultsFluorescence imaging revealed ISF transport along the linea alba, with tracers migrating linearly, a pattern abolished by surgical blockade. Abnormal ISF transport in the linea alba may affect the homeostasis of reproductive hormone levels. …”
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Harnessing lipid metabolism modulation for improved immunotherapy outcomes in lung adenocarcinoma by Yu Chen, Yang Chen, Yu Zhou, Yongsheng Li, Ran Ren, Juan Lei

“…Recent research suggests that abnormal lipid metabolism in patients with lung adenocarcinoma may hinder the efficacy of anti-PD-1 monotherapy.Methods Here, we delved into the patterns of lipid metabolism in patients with The Cancer Genome Atlas (TCGA)-lung adenocarcinoma (LUAD) and their correlation with the immune microenvironment’s cellular infiltration characteristics of the tumor. …”
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Use of Basket Trials to Solve Sleep Problems in Patients with Rare Diseases by Lara C. Pullen, Nick Bott, Cate McCanless, Amee Revana, Gunes Sevinc, Casey Gorman, Alexandra Duncan, Sarah Poliquin, Anna C. Pfalzer, Katie Q. Schmidt, E. Robert Wassman, Chère Chapman, Maria Picone

“…Food and Drug Administration regarding abnormal sleep patterns in various rare diseases. Last, in response to the profound unmet medical needs of patients with rare diseases and sleep disorders, we propose adapting and using the clinical trial design known as a “basket trial”. …”
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Adipose-derived stem cells alleviate acute pancreatitis by inhibiting ferroptosis and oxidative damage in canines by Yansong Ge, Mingzhen Chen, Meilin Li, Zheng Wang, Ruxin Ding, Zhiying Wan, Enshuang Xu, Jiasan Zheng

“…Conclusions ADSCs can protect the pancreas of dogs by inhibiting ferroptosis and oxidative stress via paracrine function, indicating immense potential as a therapeutic target for treating AP.…”
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An approach to arousal disorder classification using deformable convolution and adaptive multiscale features in EEG signals by Andia Foroughi, Fardad Farokhi, Fereidoun Nowshiravan Rahatabad, Alireza Kashaninia

“…Our proposed model, a hierarchical multiscale deformable attention module, excels at detecting complex and abnormal patterns in EEG data. We apply this model after segmenting EEG data into 30-second windows and generating spectrogram images. …”
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Adolescent scoliosis in autism spectrum disorder: is it idiopathic or syndromic?? by Ravi Rajendra, Matthew B. Bratton, Claudia Leonardi, R. Carter Clement

“…Our study at a high-volume scoliosis center compares patterns of scoliosis in ASD patients with those of neurotypical patients. …”
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Multiomics reveals metformin’s dual role in gut microbiome remodeling and hepatic metabolic reprogramming for MAFLD intervention by Yuan-dong Sun, Hao Zhang, Xiao-long Gong, Yuan-min Li, Ruiqin Han, Chun-xiao Zhou, Jian-jun Han

“…Metabolomic and lipidomic analyses revealed that metformin corrected abnormal lipid metabolism patterns, reduced hepatic fat deposition, and influenced key metabolic pathways associated with MAFLD progression. …”
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Effects of high CO2 treatment on green-ripening and peel senescence in banana and plantain fruits by Mu-bo SONG, Lu-ping TANG, Xue-lian ZHANG, Mei BAI, Xue-qun PANG, Zhao-qi ZHANG

“…In contrast to the differentiated color changing patterns, the patterns of the softening, starch degradation and soluble sugar accumulation in the pulp of 20% CO2 treated bananas and plantains displayed similarly as the patterns in the fruits ripening in regular air, indicating that the pulp ripening was not inhibited by 20% CO2, and the abnormal ripening of bananas in 20% CO2 can be considered as green ripening. …”
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Tanshinone I Ameliorates Psoriasis-Like Dermatitis by Suppressing Inflammation and Regulating Keratinocyte Differentiation by Wang Q, Luo X, Su Y, Jin Y, Kuang Q, Li S, Shen W, Zhu Y

“…Additionally, Tan-I restored keratin expression patterns, increasing K1 and decreasing K6 and K17 levels in both mouse skin and HaCaT cells.Conclusion: Tan-I is a promising therapeutic candidate for psoriasis, effectively mitigating inflammation, normalizing keratinocyte differentiation, and inhibiting abnormal keratinocyte apoptosis.Keywords: psoriasis, tanshinone I, immune modulation, keratinocyte, apoptosis…”
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Derotational osteotomy is a relevant procedure in the management of lateral patellar dislocation: An expert survey of the International Patellofemoral Study Group by Guido Wierer, Danko Milinkovic, Gerd Seitlinger, Michael Liebensteiner, William Post, Philipp W. Winkler

“…The most important factors for performing derotational osteotomy are abnormal torsion (100%), abnormal gait pattern (57%), revision cases (74%) and recurrent patellar instability (61%). …”
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Multi-omics analysis identifies a liquid-liquid phase separation-related subtypes in head and neck squamous cell carcinoma by Peng-Lei Zhai, Peng-Lei Zhai, Meng-Min Chen, Meng-Min Chen, Meng-Min Chen, Qi Wang, Jing-Jun Zhao, Xiao-Mei Tang, Cui-Ni Lu, Jia Liu, Qin-Xin Yang, Ming-Liang Xiang, Qing-Hai Tang, Biao Gu, Shu-Ping Zhang, Si-Ping Tang, Da Fu, Da Fu

“…The LPRS also showed significant correlations with the clinicopathological features and TIME patterns in HNSCC patients. Furthermore, the LPRS effectively predicted responses to immune checkpoint inhibitor therapy and facilitated the screening of potential small-molecule compounds for treating HNSCC patients.ConclusionThis study presents a new classification system for HNSCC patients grounded in LLPS. …”
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Chromatin modifiers in endometriosis pathogenesis by K. A. Abaeva, R. T. Murtazova, I. A. Vaniev, A. V. Lazarova, A. A. Sozaeva, M. A. Gogichaeva, A. A. Pirozhnikova, K. V. Ignashev, M. S. Dadashov, D. V. Kolesnikova, A. A. Bayramova, V. E. Kucherskaya, L. D. Zulfalieva, A. M. Zaitseva

“…It was revealed that various epigenetic abnormalities may play an important role in the endometriosis pathogenesis. …”
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Histological profiling of the extracellular matrix of streptozotocin-induced diabetic nephropathy in experimental mice and rats, an analytical study by Anas K. Al Makhzoomi

“…Diabetic nephropathy (DN) is characterized by dysfunction and a complication of the extracellular matrix (ECM) with an abnormal pattern of Glycosaminoglycan (GAG) synthesis. …”
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