Diagnosis of Pediatric-Type Follicular Lymphoma in Young Adults (Own Data) by AM Kovrigina, LV Plastinina, SK Kravchenko, ES Nesterova, TN Obukhova

“…Results. The morphological pattern was typical for FL 3B (n = 2) and FL 3 with blastoid nucleus morphology (n = 3). …”
Get full text

A lung cancer mouse model system based on an inbred C3H strain: Ultrasound imaging, pathological analysis, and proteomic biomarker identification by Ulayatul Kustiati, Wahyu Tri Widayati, Dwi Liliek Kusindarta, Dwi Aris Agung Nugrahaningsih, Dinda Aliffia, Wilda Bunga Tina Sanjaya, Hevi Wihadmadyatami

“…Materials and Methods: Twelve male inbred C3H mice were assigned to non-treated and treatment groups, with the latter receiving 100 mg/kg body weight of benzo(a)pyrene intraperitoneally. …”
Get full text

Dynamics of cerebral blood flow following sertraline treatment in adolescent depression by Wenyu Ren, Wenyu Ren, Xiao Liu, Zhiwei Zhang, Xiaoqin Zhang, Wei Wu, Xingyu Wang, Zhihui Yu, Chuan Liu, Renqiang Yu

“…While prior studies have explored CBF abnormalities in depressed adolescents, the specific patterns of CBF changes following pharmacological interventions, particularly with selective serotonin reuptake inhibitors (SSRIs) such as sertraline, remain insufficiently characterized.ObjectiveTo investigate the alterations in CBF induced by an 8-week sertraline treatment in adolescents with depression, and to assess whether baseline CBF can serve as a potential biomarker for predicting treatment response.MethodsA total of 40 adolescents diagnosed with depression and 31 age- and sex-matched healthy controls were enrolled in the study. …”
Get full text

ZYGOMYCOSIS IN IMMUNOCOMPROMISED NON-HAEMATOLOGICAL PATIENTS by George Petrikkos, Miranda Drogari-Apiranthitou

“…Suspicion index can be increased through recognition of the differential patterns of clinical presentation. In the <span style="mso-bidi-font-weight: bold;">non</span><strong style="mso-bidi-font-weight: normal;">-</strong> haematological <span style="mso-bidi-font-weight: bold;">immunocompromised </span>patients, zygomycosis can manifest in various clinical forms, depending on the underlying condition: mostly as rhino-orbital or rhino-cerebral in diabetes patients, pulmonary infection in patients with malignancy or solid organ transplantation, disseminated infection in iron overloaded or deferoxamine treated patients, cerebral - with no sinus involvement - in ID users, gastrointestinal in premature infants or malnourishment, and cutaneous after direct inoculation in immunocompetent individuals with trauma or burns.…”
Get full text

NEUROPSYCHIATRIC DISORDERS IN JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: RESULTS FROM A RETROSPECTIVE STUDY by M. I. Kaleda, I. P. Nikishina, S. I. Glukhova, N. Yu. Stepanenko

“…Objective: to analyze clinical features and immunological abnormalities in juvenile-onset systemic lupus erythematosus (SLE) with neurolupus and to compare findings with the data available in the literature.Subjects and methods. …”
Get full text

Reduction of subclinical acute cardiac injury through DIBH radiotherapy: a single-institution real-world clinical cohort analysis by Kun Zhang, Jing Shen, Yongguang Liang, Xiangyin Meng, Bo Yang, Jiabin Ma, Ke Hu, Jie Qiu, Xiaorong Hou, Fuquan Zhang

“…Subclinical acute cardiac injury was characterized by the emergence of elevated myocardial enzymes beyond normal levels and/or EKG alterations in ST-T or T-wave patterns and/or abnormalities detected in ECHO within a 6-month period following radiotherapy. …”
Get full text

<i>DEPDC5</i> mutations in familial epilepsy syndrome: genetic insights and therapeutic approaches by M. K.C. Diallo, S. Mukesh, L. Kapil, R. Singla, D. Tar, S. N. Tammineedi, E. Singer, H. Chhayani, K. Arumaithurai, U. K. Patel, R. Arora

“…This mutation has shown to be inherited in familial pattern. This R389H variant is not present in the 1000 genomes database and is predicted to be benign. …”
Get full text

SUBCLINICAL INTERSTITIAL PULMONARY INJURY IN RHEUMATOID ARTHRITIS by D. V. Bestaev, L. A. Bozhyeva, A. V. Volkov, A. A. Novikov, S. I. Glukhova, E. L. Nasonov

“…The study enrolled 61 inpatients diagnosed with RA (according to the 1987 American College of Rheumatology criteria) who were treated at the V.A. Nasonova Research Institute of Rheumatology; in so doing, high-resolution computed tomography revealed lung changes as a ground glass pattern in 15 patients, reticular striation, traction bronchoectases, and lung tissue changes as honeycomb ones in 25 patients; no lung abnormalities were found in 21 patients. …”
Get full text

Homozygous Mutation in the FANCD2 Gene Observed in a Saudi Male Infant with Severe Ambiguous Genitalia by Aida Al Jabri, Nusaybah Al Naim, Abeer Al Dossari

“…FA characterizes by multiple congenital abnormalities and malformations including growth retardation, renal agenesis, absence of radial bones and thumbs as well, progressive bone marrow failure, irregular skin pigmentation patterns, and increased susceptibility to cancer. …”
Get full text

Oral High-Dose Thiamine Improves the Symptoms of Chronic Cluster Headache by Costantini Antonio, Tiberi Massimo, Zarletti Gianpaolo, Pala Maria Immacolata, Trevi Erika

“…Some authors have found in patients affected by this disease abnormality in glucose metabolism. Considering the role of thiamine in brain function, in energetic metabolism, and in pain modulation, we treated a patient affected by cluster headache with oral high-dose thiamine. …”
Get full text

Assessment of the gold nanoparticles biosynthesized using Casuarina equisetifolia bark extract against the ethion induced Hepato- and neurotoxicity in rats by Wael Mahmoud Aboulthana, Noha El-Sayed Ibrahim, Amal Gouda Hussien, Amgad Kamal Hassan, Wagdy K.B. Khalil, Hassan Abdel-Gawad, Hamdy Ahmed Taha, Ayda K. Kelany, Kawkab A. Ahmed

“…The protein and isoenzyme patterns were also assayed using an electrophoretic technique. …”
Get full text

Role of individual and combined impact of simvastatin and α-TCP in rat calvarial bone defect: An experimental study by Surendar Sugumaran, Deepak Selvam, M.S. Nivedhitha, Karthik Ganesh Mohanraj, Bader O. Almutairi, Selvaraj Arokiyaraj, Ajay Guru, Jesu Arockiaraj

“…Background: Bone substitutes have been used by doctors for a long time to treat osseous abnormalities. Recently, scientists have been searching for suitable materials to replace bone. …”
Get full text

Autism and α7-nicotinic acetylcholine receptors: new pharmacological and herbal interventions by Nourhan A. Khattab, Aya H. El-Kadem, Nada A. Ashour, Nageh Ahmed El-Mahdy, Nagla A. El-Shitany

“…ASD is characterized by neurological abnormalities that include impaired social interactions, stereotyped patterns of behavior, and cognitive difficulties. …”
Get full text

Midgut volvulus without intestinal malrotation in a teenager: a case report by Yasmine Houas, Alma Baccouche, Nader Bennour Ghaddab, Sirine Fkaier, Riadh Jouini

“…Abdominal X-rays were inconclusive, showing nonspecific bowel gas patterns. An abdominal ultrasound showed no definitive abnormalities. …”
Get full text

Integral approach to organelle profiling in human iPSC-derived cardiomyocytes enhances in vitro cardiac safety classification of known cardiotoxic compounds by Brigitta R. Szabo, Brigitta R. Szabo, Jeroen Stein, Anna Savchenko, Thomas Hutschalik, Thomas Hutschalik, Filip Van Nieuwerburgh, Tim Meese, Georgios Kosmidis, Paul G. A. Volders, Elena Matsa, Elena Matsa, Elena Matsa, Elena Matsa

“…Current preclinical hiPSC-CMs models focus on functional changes such as electrophysiological abnormalities, however other parameters, such as structural toxicity, remain less understood.MethodsThis study utilized hiPSC-CMs from three independent donors, cultured in serum-free conditions, and treated with a library of 17 small molecules with stratified cardiac side effects. …”
Get full text

Ophthalmological manifestations and plasma markers of inflammation in Ebola survivors in post-treatment era by Jean-Claude Mwanza, Alexis K. Kahindo, Justin Mbusa-Kombi, Martial V. Mumbere, Richard O. Kitenge, David R. McIlwain, Jean Christophe S. Mulangu, Placide K. Mbala, Daniel Okitundu, Bruno J. Giordani, Michael J. Boivin, Alla Sikorskii, Nelly N. Kabedi, Jessica G. Shantha, Steven Yeh, Dieudonne N. Mumba, Desire Tshala-Katumbay

“…We conclude that in treated EVD survivors, optic neuropathy was the only neuro-ophthalmologic abnormality. …”
Get full text

Clinical and imaging features of parenchymal and non-parenchymal neuro-Behçet’s disease: a systematic review of case reports and series by Omar Al-omoush, Majd M. AlBarakat, Deya’a Alasmar, Ali Al-Khalaileh, Ahmad Alzoubi, Husam Tarakhan, Zaid Shakhatreh, Zaid Hatamleh, Mohammed Abu-saleh, Othman Saleh, Abdalrahman Altiti, Wafa’ A. Hazaymeh, Sakhr Alshwayyat, Hamdah Hanifa, Ethar Hazaimeh

“…While previous research highlights MRI abnormalities and cerebrospinal fluid changes, there hasn’t been a systematic effort to identify patterns specific to newly diagnosed patients. …”
Get full text

Healthy Eating Index-2020 and bowel habits: a cross-sectional analysis of NHANES by Rongpeng Chen, Zexin Fu, Zhicheng Feng, Feng Xiao, Guoqiang Wang

“…The relationship between dietary patterns, measured using the Healthy Eating Index-2020 (HEI-2020), and bowel habits remains unclear. …”
Get full text

Reliability of Scapula Clinical Assessment and Effectiveness of Scapular-Focused Exercises in a Non-Athletic Population with Shoulder Pain – a Literature Review by Maciej Olszewski, Sara Gamrot, Joanna Golec, Elżbieta Szczygieł

“…Scapular movement abnormalities have been defined as scapular dyskinesis. …”
Get full text

Novel cerebrospinal fluid anti-central nervous system IgG antibodies can identify immunotherapy-responsive neuropsychiatric disorders by Hannah Preßler, Hannah Preßler, Isabel Bünger, Isabel Bünger, Isabel Bünger, Harald Prüss, Harald Prüss

“…Memory impairment (73%) and psychiatric abnormalities (64%) were the most frequent symptoms. …”
Get full text