Comprehensive Profiling of Transcriptome and m6A Epitranscriptome Uncovers the Neurotoxic Effects of Yunaconitine on HT22 Cells by Beian Lin, Jian Zhang, Mengting Chen, Xinyue Gao, Jiaxin Wen, Kun Tian, Yajiao Wu, Zekai Chen, Qiaomei Yang, An Zhu, Chunhong Du

“…Objective: To explore different mRNA transcriptome patterns and RNA N6-methyladenosine (m6A) alteration in yunaconitine (YA)-treated HT22 mouse hippocampal neuron, and uncover the role of abnormal mRNA expression and RNA m6A modification in YA-induced neurotoxicity. …”
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Effects of high CO2 treatment on green-ripening and peel senescence in banana and plantain fruits by Mu-bo SONG, Lu-ping TANG, Xue-lian ZHANG, Mei BAI, Xue-qun PANG, Zhao-qi ZHANG

“…In contrast to the differentiated color changing patterns, the patterns of the softening, starch degradation and soluble sugar accumulation in the pulp of 20% CO2 treated bananas and plantains displayed similarly as the patterns in the fruits ripening in regular air, indicating that the pulp ripening was not inhibited by 20% CO2, and the abnormal ripening of bananas in 20% CO2 can be considered as green ripening. …”
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Restrictive Cardiomyopathies: The Importance of Noninvasive Cardiac Imaging Modalities in Diagnosis and Treatment—A Systematic Review by Aidonis Rammos, Vasileios Meladinis, Georgios Vovas, Dimitrios Patsouras

“…Electrocardiographic findings are nonspecific and include atrioventricular conduction and QRS complex abnormalities and supraventricular and ventricular arrhythmias. …”
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Families’ Lived Experience of Raising and Caring for Early-onset Scoliosis: A Pilot Study by Hsiao-Hui Chiu, Chia-Jung Wu, Man-Ling Lin, Shiang-Feng Wu, Chi-Kuang Feng, Yu-Cheng Yao

“…Subsequently, we reviewed and analyzed the interview transcripts word by word to identify key themes and patterns. Results: We found four distinct stages in the families’ adaptation process: (1) discovering the abnormal body appearance or function of children; (2) seeking help from famous doctors; (3) adapting daily life to the disease and therapy; and (4) training to overcome the suffering caused by the disease. …”
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Ultrasound-Guided Botulinum Toxin Injections for Hand Spasticity: A Technical Guide for the Dorsal Approach by Calogero Malfitano, Antonio Robecchi Majnardi, Arianna Pesaresi, Vincenzo Ricci

“…The authors suggest a novel dorsal approach to treat the most common abnormal postural patterns in hand spasticity, thumb-in-palm, and intrinsic plus. …”
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ZYGOMYCOSIS IN IMMUNOCOMPROMISED NON-HAEMATOLOGICAL PATIENTS by George Petrikkos, Miranda Drogari-Apiranthitou

“…Suspicion index can be increased through recognition of the differential patterns of clinical presentation. In the non- haematological immunocompromised patients, zygomycosis can manifest in various clinical forms, depending on the underlying condition: mostly as rhino-orbital or rhino-cerebral in diabetes patients, pulmonary infection in patients with malignancy or solid organ transplantation, disseminated infection in iron overloaded or deferoxamine treated patients, cerebral - with no sinus involvement - in ID users, gastrointestinal in premature infants or malnourishment, and cutaneous after direct inoculation in immunocompetent individuals with trauma or burns. …”
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Evaluation of some photosensitizers against the cotton leaf worm, Spodoptera littoralis (Lepidoptera: Noctuidae), in relation to spectral and thermal reflectance by M. S. Yones, Shireen A. M. Maamoun, Abd El Aziz A. Khidr, Mahmoud Sayed, Hend A. A. Al-Ashry, Radwa G. Attia

“…Larvae fed on photosensitizing compounds showed distinct spectral reflectance patterns. Treated larvae had same reflectance manner; which were higher than that of control samples. …”
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Impact of polystyrene microplastics (PS-MPs) on the entire female mouse reproductive cycle: Assessing reproductive toxicity of microplastics through in vitro follicle culture by Jukyeong Jeong, Nhu Thi Quynh Mai, Byoung-San Moon, Jung Kyu Choi

“…Immunohistochemistry showed increased Cleaved Caspase 3 and decreased Bcl2 levels in PS-MPs-treated groups, indicating apoptosis in granulosa cells. …”
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Evaluation of Parasiticide Treatment with Benznidazol in the Electrocardiographic, Clinical, and Serological Evolution of Chagas Disease. by Abilio Augusto Fragata-Filho, Francisco Faustino França, Claudia da Silva Fragata, Angela Maria Lourenço, Cristiane Castro Faccini, Cristiane Aparecida de Jesus Costa

“…The occurrence of electrocardiographic abnormalities and relevant clinical events (heart failure, stroke, total mortality, and cardiovascular death) was less prevalent in treated patients (p <0.001, p: 0.022, p: 0.047 respectively). …”
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In Vitro Influenza A Virus-Inactivating Activity of HIDROX^®, Hydroxytyrosol-Rich Aqueous Olive Pulp Extract by Mayar Yasser Zeinelabideen Mohamed, Dulamjav Jamsransuren, Sachiko Matsuda, Koichi Narita, Toshihiro Murata, Haruko Ogawa, Yohei Takeda

“…In HT treatment but not HIDROX treatment, the virucidal activity disappeared, and the induction of abnormal band patterns of a viral protein in WB was cancelled by ROS/RNS scavenger activity. …”
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Emergency Dental Care During the SARS-CoV-2 Pandemic and Its Effect on Medication-Related Osteonecrosis of the Jaw: A Retrospective Study in Hungary by Gabor Kammerhofer, Daniel Vegh, Petra Papocsi, Martin Major, Patrik Fuzes, Mihaly Vaszilko, Marta Ujpal, Kata Sara Haba, Gyorgy Szabo, Zsolt Nemeth

“…The average fasting glucose levels were 5.5 and 5.9 mmol/L in the pre- and post-COVID-19 groups, respectively. Localization patterns shifted, with a higher incidence in the maxilla in the post-COVID-19 group. …”
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Ophthalmic Treatment and Vision Care of a Patient with Rare Ring Chromosome 15: A Case Report by Lidia Puchalska-Niedbał, Stanisław Zajączek, Elżbieta Petriczko, Urszula Kulik

“…Ring chromosome 15 is a very rare genetic abnormality with a wide spectrum of clinical findings. …”
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Pulmonary Circulation in Acute Lung Injury in the Presence of Acute Poisoning by Toxic Substances by A. N. Lodyagin, G. A. Livanov, I. P. Nikolayeva, B. V. Batotsyrenov, G. V. Shestova

“…The development of a critical condition determines the degree of pulmonary hyperhydration that depends on the pattern of cardiovascular abnormalities (a fall of single cardiac performance and pulmonary microcirculato-ry disorders). …”
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Decoding Cuproptosis-Sphingolipid-Immune Crosstalk in Atopic Dermatitis: A Multi-Omics Network Analysis by Xiaowen Wen, Shulin Jia, Jing Wu, Suitian Wang, Teng Yu, Haoyou Xu

“…Notably, immune infiltration analysis demonstrated abnormal activity in 20 out of 21 immune cell types, particularly Th2 cells and macrophages, which showed strong correlations with CRG expression patterns. …”
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Imaging observation of intervertebral disc degeneration in patients with old thoracolumbar fracture-related kyphotic deformity by Xi-long Cui, Ao Ding, Wen Yin, Wan-mei Yang, Wei Zhang, Hao Wu, Ji-shi Jiang, Yun-lei Zhai, Zi-kai Hua, Hai-yang Yu

“…We hypothesized that patients with OTLFK exhibit distinct patterns of disc degeneration compared to those with chronic low back pain without kyphotic deformity. …”
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Maculopathy after long-term use of fondaparinux, a heparin mimetic and heparanase inhibitor by Benjamin R. Lin, Erick Rivera-Grana, Wenting Zhou, Mark Barakat, Philip J. Rosenfeld, Janet L. Davis

“…This case is relevant for research into pharmacologic uses of heparanase inhibitors and monitoring for retinal disease in patients treated with them.…”
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Clinical profile and management outcomes of paediatric undescended testes in a Nigerian tertiary hospital: An 11-year review by Ituen MA, Akpanudo EI, Eyo AE, Emmanuel EM

“… Context: Undescended testis (UDT) is a common urogenital abnormality in male children, and early intervention is imperative to prevent impaired spermatogenesis or malignant transformation. …”
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Reactive Pancreatitis Following Endoscopic Retrograde Cholangiopancreatography: Diagnosis, Prevention and Treatment by Ye. V. Moroz, V. N. Ardashev, M. P. Mantserov, K. V. Dzyuba, V. A. Tsyrik

“…The patients’ status, the presence and pattern of subjective and objective symptoms and laboratory parameters (blood amylase, urinary diastase, leukocytosis) were dynamically estimated after ERCP.Results: 58 (28.0%) patients developed post-ERCP RP, the severe course of pancreatitis being observed in 4.3%. …”
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Extracellular vesicles derived from bone marrow mesenchymal stem cells regulate SREBF2/HMGB1 axis by transporting miR-378a-3p to inhibit ferroptosis in intestinal ischemia-reperfus... by Zan Liu, Zitong Zhao, Zhenghui Xiao, Ming Li, Xiyang Wang, Yan Huang, Yong Li

“…Using a bioinformatics database, we initially identified genes with abnormal expression patterns in II/R injury. Then, we confirmed the association between II/R injury, ferroptosis, and the HMGB1/SREBF2 axis through in vivo and in vitro experiments. …”
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E-cigarettes as a safe alternative to tobacco smoking? A deep dive into vape-associated pneumothorax (VASP) by Saquib Navid Siddiqui, Lwin Paing, Shahnawaz Hashmi, Dinath Perera, Umair Falak

“…Our retrospective study supports this outcome, coupled with the alarming fact that this is a more severe form of spontaneous pneumothorax that remains refractory to thoracostomy alone. We recommend treating VASP initially with tube thoracostomy (if symptomatic), with surgical intervention in case of refractory episodes and recurrence.…”
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