Monomorphic sustained right ventricular outflow tract tachycardia in pregnancy with favorable outcomes: a case report by Gidion Edwin, Joshua Ezekiel, Baraka Alphonce, Kelvin Masava, John Meda

“…A 12-lead electrocardiogram showed multiple monomorphic sustained ventricular tachycardia with the left bundle branch block pattern suggestive of right ventricular outflow tract tachycardia. …”
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The predictive value of changes in 18F-FDG PET/CT cardiac uptake patterns and metabolic parameters for anthracycline based chemotherapy induced cardiac toxicity in lymphoma patient... by Runlong Lin, Aijuan Tian, Ying Wang, Xiaomei Wang, Xin Yuan, Jing Yu, Guihua Li, Wenli Xie

“…Analyzing changes in uptake patterns, the group displaying abnormal changes exhibited an increase in left atrial diameter and a decrease in left ventricular ejection fraction compared to the group with normal changes. …”
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Derotational osteotomy is a relevant procedure in the management of lateral patellar dislocation: An expert survey of the International Patellofemoral Study Group by Guido Wierer, Danko Milinkovic, Gerd Seitlinger, Michael Liebensteiner, William Post, Philipp W. Winkler

“…The most important factors for performing derotational osteotomy are abnormal torsion (100%), abnormal gait pattern (57%), revision cases (74%) and recurrent patellar instability (61%). …”
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Histological profiling of the extracellular matrix of streptozotocin-induced diabetic nephropathy in experimental mice and rats, an analytical study by Anas K. Al Makhzoomi

“…Diabetic nephropathy (DN) is characterized by dysfunction and a complication of the extracellular matrix (ECM) with an abnormal pattern of Glycosaminoglycan (GAG) synthesis. …”
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Biomechanical analysis of elastic fixation for lisfranc injuries with finite elements method by Yang Liu, Wen Lu, Wei Liu, Wang-sheng Wu, Cheng-wei Wang

“…Nonetheless, each pretension level exhibited a unique stress distribution pattern. At 70 N of pretension, elastic fixation achieved biomechanical stability comparable to that of the normal foot model. …”
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Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats by Yaoyao Zhu, Ge Lu, Weixin Li, Chenchen Su, Pengfei Du, Shuyou Wang, Li Yang, Huanfang Xu, Yigong Fang, Xiaojing Song

“…In addition, we investigated the ovarian functional changes post-ISF obstruction and evaluated the therapeutic effects of acupuncture on ovarian dysfunction in aged rats, both in unblocked and ISF-blockade conditions.ResultsFluorescence imaging revealed ISF transport along the linea alba, with tracers migrating linearly, a pattern abolished by surgical blockade. Abnormal ISF transport in the linea alba may affect the homeostasis of reproductive hormone levels. …”
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Can Emotional and Behavioral Dysregulation in Youth Be Decoded from Functional Neuroimaging? by Liana C L Portugal, Maria João Rosa, Anil Rao, Genna Bebko, Michele A Bertocci, Amanda K Hinze, Lisa Bonar, Jorge R C Almeida, Susan B Perlman, Amelia Versace, Claudiu Schirda, Michael Travis, Mary Kay Gill, Christine Demeter, Vaibhav A Diwadkar, Gary Ciuffetelli, Eric Rodriguez, Erika E Forbes, Jeffrey L Sunshine, Scott K Holland, Robert A Kowatch, Boris Birmaher, David Axelson, Sarah M Horwitz, Eugene L Arnold, Mary A Fristad, Eric A Youngstrom, Robert L Findling, Mirtes Pereira, Leticia Oliveira, Mary L Phillips, Janaina Mourao-Miranda

“…We aimed to use functional neuroimaging and pattern regression techniques to determine whether patterns of brain activity could accurately decode individual-level severity on a dimensional scale measuring behavioural and emotional dysregulation at two different time points.…”
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The sexually dimorphic expression of glutamate transporters and their implication in pain after spinal cord injury by Jennifer M. Colón-Mercado, Aranza I. Torrado-Tapias, Iris K. Salgado, José M. Santiago, Samuel E. Ocasio Rivera, Dina P. Bracho-Rincon, Luis H. Pagan Rivera, Jorge D. Miranda

“…The dimorphic expression revealed in this study provides a therapeutic opportunity for treating chronic pain, an area with a critical need for treatment.…”
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Heart Failure with Preserved Left Ventricular Ejection Fraction: A Complex Conundrum Simply Not Limited to Diastolic Dysfunction by Angel Lopez-Candales, Talal Asif, Khalid Sawalha, Nicholas B. Norgard

“…Over the last two decades, the changing paradigm of heart failure with preserved ejection fraction (HFpEF) has transformed our understanding not only of the pathophysiology of this clinical entity but also the diagnostic and therapeutic approaches aimed at treating this complex patient population. No longer HFpEF should be seen as simply left ventricular diastolic dysfunction but as a group of that in addition of having small and thick left ventricles with abnormal diastolic filling patterns as their main pathophysiologic abnormality; they also have whole host of different abnormalities. …”
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The Potential Biological Roles and Clinical Significance of Anaphase-Promoting Complex Subunit 1 in Colorectal Cancer by Yi Chen MD, Yu-Xing Tang MD, Da-Tong Zeng MD, Jia-Ying Wen MD, Yan-Ting Zhan MD, Dong-Ming Li MD, Rong-Quan He MD, Zhi-Guang Huang MD, Yu-Zhen Chen MD, Qiu-Yu Wei MD, Gang Chen PhD, Yu-Lu Tang MD, Hui Li MD

“…Materials and methods This study integrated 2329 mRNA expression data, single-cell RNA sequencing (scRNA-seq), and internal immunohistochemistry of 416 tissue samples to comprehensively evaluate the abnormal expression pattern of ANAPC1 in CRC. It also incorporated evidence from immune infiltration analysis, functional enrichment analysis, and weighted gene co-expression network analysis to explore the biological behaviour of ANAPC1 in CRC. …”
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Effect of Aqueous and Ethanolic Extracts of Tribulus terrestris, Phoenix dactylifera and Nasturtium officinale Mixture on Some Reproductive Parameters in Male Mice by Baghdad Science Journal

“…The results showed a dose dependent pattern of activity and the effect of the extracts were enhanced with increasing the dose level. …”
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Multiomics reveals metformin’s dual role in gut microbiome remodeling and hepatic metabolic reprogramming for MAFLD intervention by Yuan-dong Sun, Hao Zhang, Xiao-long Gong, Yuan-min Li, Ruiqin Han, Chun-xiao Zhou, Jian-jun Han

“…Metabolomic and lipidomic analyses revealed that metformin corrected abnormal lipid metabolism patterns, reduced hepatic fat deposition, and influenced key metabolic pathways associated with MAFLD progression. …”
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The Efficacy and Brain Network Mechanism of Acupuncture for Knee Osteoarthritis: A Study Protocol for Randomized Controlled Neuroimaging Trial by Sun YY, Wang ML, Zhao RH, Hao MY, Song S, Zhou Y, Zhang N

“…Therefore, this study uses KOA as the research vehicle, focuses on the abnormal connectivity patterns of brain functional networks, and integrates clinical pain assessments to thoroughly investigate the central mechanisms of acupuncture therapeutic effects on KOA.Patients and Methods: In this parallel, randomized, sham-controlled neuroimaging trial, 60 KOA patients will be randomly divided into the acupuncture group and sham acupuncture group in a 1:1 ratio, treated three times weekly for a total of 12 sessions. …”
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Heterotaxy polysplenia syndrome with cholangiopancreatic cancer: a case report and literature review by Ziye Chen, Ziye Chen, Yu-Ann Chen, Yu-Ann Chen, Xuedong Wang, Wenyan Song, Wenyan Song, Yadi Geng, Yadi Geng, Pengfei Wang, Siming Kong, Jiahong Dong, Jiahong Dong, Hui Bai, Yunfang Wang, Yunfang Wang, Yunfang Wang, Yunfang Wang

“…BackgroundHeterotaxy polysplenia syndrome is a rare condition characterized by multiple abnormal spleens and irregular placement of various organs. …”
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Deconvolution of serum cortisol levels by using compressed sensing. by Rose T Faghih, Munther A Dahleh, Gail K Adler, Elizabeth B Klerman, Emery N Brown

“…Identification of the amplitude and timing of pulsatile hormone release allows (i) quantifying of normal and abnormal secretion patterns towards the goal of understanding pathological neuroendocrine states, and (ii) potentially designing optimal approaches for treating hormonal disorders.…”
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Psychological stress dysfunction in women with premenstrual syndrome by Qing Liu, Yuhang Lin, Wenjuan Zhang

“…Despite its prevalence, the neural mechanisms underlying PMS—particularly those related to stress—are not fully understood.This review aims to explore the complex interactions between PMS and stress, with a focus on the hormonal pathways involved. We propose that abnormal stress coping styles and stress reactivity patterns, collectively referred to as stress dysfunction, are crucial factors influencing women's vulnerability to PMS. …”
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BERT-based network for intrusion detection system by Yong Yang, Xing Peng

“…By treating network traffic as a “language,” our approach resolves issues that traditional methods struggle with while being scalable and adaptable to various network environments and attack patterns.…”
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Rare Encounter Behind the Ear: Unveiling Kimura Disease in the Postaural Region by Divya Nayani, Siddhartha Nyathani, Rahul Kumar Pitale Ashok

“…Its etiology, linked to an abnormal allergic reaction, remains uncertain, featuring a characteristic indolent growth pattern. …”
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Clinical Features of Liver Injury Induced by Immune Checkpoint Inhibitors in Japanese Patients by Koji Imoto, Motoyuki Kohjima, Tomonobu Hioki, Tomoyuki Kurashige, Miho Kurokawa, Shigeki Tashiro, Hideo Suzuki, Akifumi Kuwano, Masatake Tanaka, Seiji Okada, Masaki Kato, Yoshihiro Ogawa

“…Methods. Among 387 patients treated with ICIs, those who developed drug-induced liver injury were investigated. …”
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Use of Basket Trials to Solve Sleep Problems in Patients with Rare Diseases by Lara C. Pullen, Nick Bott, Cate McCanless, Amee Revana, Gunes Sevinc, Casey Gorman, Alexandra Duncan, Sarah Poliquin, Anna C. Pfalzer, Katie Q. Schmidt, E. Robert Wassman, Chère Chapman, Maria Picone

“…Food and Drug Administration regarding abnormal sleep patterns in various rare diseases. Last, in response to the profound unmet medical needs of patients with rare diseases and sleep disorders, we propose adapting and using the clinical trial design known as a “basket trial”. …”
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