Effects of high CO2 treatment on green-ripening and peel senescence in banana and plantain fruits by Mu-bo SONG, Lu-ping TANG, Xue-lian ZHANG, Mei BAI, Xue-qun PANG, Zhao-qi ZHANG

“…In contrast to the differentiated color changing patterns, the patterns of the softening, starch degradation and soluble sugar accumulation in the pulp of 20% CO2 treated bananas and plantains displayed similarly as the patterns in the fruits ripening in regular air, indicating that the pulp ripening was not inhibited by 20% CO2, and the abnormal ripening of bananas in 20% CO2 can be considered as green ripening. …”
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Multi-omics analysis identifies a liquid-liquid phase separation-related subtypes in head and neck squamous cell carcinoma by Peng-Lei Zhai, Peng-Lei Zhai, Meng-Min Chen, Meng-Min Chen, Meng-Min Chen, Qi Wang, Jing-Jun Zhao, Xiao-Mei Tang, Cui-Ni Lu, Jia Liu, Qin-Xin Yang, Ming-Liang Xiang, Qing-Hai Tang, Biao Gu, Shu-Ping Zhang, Si-Ping Tang, Da Fu, Da Fu

“…The LPRS also showed significant correlations with the clinicopathological features and TIME patterns in HNSCC patients. Furthermore, the LPRS effectively predicted responses to immune checkpoint inhibitor therapy and facilitated the screening of potential small-molecule compounds for treating HNSCC patients.ConclusionThis study presents a new classification system for HNSCC patients grounded in LLPS. …”
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Tanshinone I Ameliorates Psoriasis-Like Dermatitis by Suppressing Inflammation and Regulating Keratinocyte Differentiation by Wang Q, Luo X, Su Y, Jin Y, Kuang Q, Li S, Shen W, Zhu Y

“…Additionally, Tan-I restored keratin expression patterns, increasing K1 and decreasing K6 and K17 levels in both mouse skin and HaCaT cells.Conclusion: Tan-I is a promising therapeutic candidate for psoriasis, effectively mitigating inflammation, normalizing keratinocyte differentiation, and inhibiting abnormal keratinocyte apoptosis.Keywords: psoriasis, tanshinone I, immune modulation, keratinocyte, apoptosis…”
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The Potential Biological Roles and Clinical Significance of Anaphase-Promoting Complex Subunit 1 in Colorectal Cancer by Yi Chen MD, Yu-Xing Tang MD, Da-Tong Zeng MD, Jia-Ying Wen MD, Yan-Ting Zhan MD, Dong-Ming Li MD, Rong-Quan He MD, Zhi-Guang Huang MD, Yu-Zhen Chen MD, Qiu-Yu Wei MD, Gang Chen PhD, Yu-Lu Tang MD, Hui Li MD

“…Materials and methods This study integrated 2329 mRNA expression data, single-cell RNA sequencing (scRNA-seq), and internal immunohistochemistry of 416 tissue samples to comprehensively evaluate the abnormal expression pattern of ANAPC1 in CRC. It also incorporated evidence from immune infiltration analysis, functional enrichment analysis, and weighted gene co-expression network analysis to explore the biological behaviour of ANAPC1 in CRC. …”
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Effect of Aqueous and Ethanolic Extracts of Tribulus terrestris, Phoenix dactylifera and Nasturtium officinale Mixture on Some Reproductive Parameters in Male Mice by Baghdad Science Journal

“…The results showed a dose dependent pattern of activity and the effect of the extracts were enhanced with increasing the dose level. …”
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Chromatin modifiers in endometriosis pathogenesis by K. A. Abaeva, R. T. Murtazova, I. A. Vaniev, A. V. Lazarova, A. A. Sozaeva, M. A. Gogichaeva, A. A. Pirozhnikova, K. V. Ignashev, M. S. Dadashov, D. V. Kolesnikova, A. A. Bayramova, V. E. Kucherskaya, L. D. Zulfalieva, A. M. Zaitseva

“…It was revealed that various epigenetic abnormalities may play an important role in the endometriosis pathogenesis. …”
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Heterotaxy polysplenia syndrome with cholangiopancreatic cancer: a case report and literature review by Ziye Chen, Ziye Chen, Yu-Ann Chen, Yu-Ann Chen, Xuedong Wang, Wenyan Song, Wenyan Song, Yadi Geng, Yadi Geng, Pengfei Wang, Siming Kong, Jiahong Dong, Jiahong Dong, Hui Bai, Yunfang Wang, Yunfang Wang, Yunfang Wang, Yunfang Wang

“…Additionally, a familial pattern of situs inversus and breast cancer was observed. …”
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Postoperative Multimodal Analysis in Successful Gas Displacement of a Submacular Hemorrhage by Tatiana Urrea-Victoria, Emiliano Fulda-Graue, Miguel A. Quiroz-Reyes, Felipe Esparza-Correa, Alejandra Nieto-Jordan, Erick A. Quiroz-Gonzalez, Federico Graue-Wiechers

“…The multimodal imaging tests yielded abnormal foveal SD-OCT patterns, with a fibrous sealed tear in the retinal pigment epithelium. …”
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Primary large B-cell lymphoma of the central nervous system misdiagnosed as autoimmune encephalitis: a case report by Aihui Ren, Guanwen Zeng, Riling Chen, Zhixing Cao, Wenyan Zhuo, Yubin Liang, Yubin Liang

“…Physical examination revealed various abnormal signs. Initial cerebrospinal fluid (CSF) analysis was unremarkable, while MRI scans (both plain and contrast-enhanced) showed abnormal signals in the left brainstem, thalamus, and basal ganglia regions, with specific enhancement patterns, and arterial spin labeling (ASL) demonstrated hyperperfusion. …”
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Clinicopathologic Features of IgG4-Related Kidney Disease by Alessia Buglioni, Sarah M. Jenkins, Samih H. Nasr, Pingchuan Zhang, Ian W. Gibson, Mariam P. Alexander, Loren P. Herrera Hernandez, Mary E. Fidler, Naoki Takahashi, Marie C. Hogan, Lynn D. Cornell

“…IgG4-RD can affect the kidney in different disease patterns, collectively referred to as IgG4-related kidney disease (IgG4-RKD). …”
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Gradient changes in bioprosthetic valve thrombosis: duration of anticoagulation and strategies to improve detection by Vuyisile T Nkomo, Alexander C Egbe, Heidi M Connolly, Patricia A Pellikka, Sorin V Pislaru, Filip Ionescu, Hartzell V Schaff, Ioana Petrescu, Jwan A Naser, Cristina Pislaru

“…We set forth to (1) evaluate patterns of increase in gradients prior to BPVT diagnosis and (2) characterise time-course of response to anticoagulation.Methods Patients treated with warfarin for BPVT (1999–2019) with clinically significant reduction of mean gradients (≥25%) were identified retrospectively. …”
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Comprehensive Profiling of Transcriptome and m6A Epitranscriptome Uncovers the Neurotoxic Effects of Yunaconitine on HT22 Cells by Beian Lin, Jian Zhang, Mengting Chen, Xinyue Gao, Jiaxin Wen, Kun Tian, Yajiao Wu, Zekai Chen, Qiaomei Yang, An Zhu, Chunhong Du

“…Objective: To explore different mRNA transcriptome patterns and RNA N6-methyladenosine (m6A) alteration in yunaconitine (YA)-treated HT22 mouse hippocampal neuron, and uncover the role of abnormal mRNA expression and RNA m6A modification in YA-induced neurotoxicity. …”
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Rare Encounter Behind the Ear: Unveiling Kimura Disease in the Postaural Region by Divya Nayani, Siddhartha Nyathani, Rahul Kumar Pitale Ashok

“…Its etiology, linked to an abnormal allergic reaction, remains uncertain, featuring a characteristic indolent growth pattern. …”
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Families’ Lived Experience of Raising and Caring for Early-onset Scoliosis: A Pilot Study by Hsiao-Hui Chiu, Chia-Jung Wu, Man-Ling Lin, Shiang-Feng Wu, Chi-Kuang Feng, Yu-Cheng Yao

“…Subsequently, we reviewed and analyzed the interview transcripts word by word to identify key themes and patterns. Results: We found four distinct stages in the families’ adaptation process: (1) discovering the abnormal body appearance or function of children; (2) seeking help from famous doctors; (3) adapting daily life to the disease and therapy; and (4) training to overcome the suffering caused by the disease. …”
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Ultrasound-Guided Botulinum Toxin Injections for Hand Spasticity: A Technical Guide for the Dorsal Approach by Calogero Malfitano, Antonio Robecchi Majnardi, Arianna Pesaresi, Vincenzo Ricci

“…The authors suggest a novel dorsal approach to treat the most common abnormal postural patterns in hand spasticity, thumb-in-palm, and intrinsic plus. …”
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Clinical Features of Liver Injury Induced by Immune Checkpoint Inhibitors in Japanese Patients by Koji Imoto, Motoyuki Kohjima, Tomonobu Hioki, Tomoyuki Kurashige, Miho Kurokawa, Shigeki Tashiro, Hideo Suzuki, Akifumi Kuwano, Masatake Tanaka, Seiji Okada, Masaki Kato, Yoshihiro Ogawa

“…Four patients in the case series showed diverse clinical features in terms of hepatotoxic pattern, symptoms, and the interval time between the initiation of immunotherapy and the onset of the hepatic irAE. …”
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Identification of a metabolic brain network characterizing essential tremor by Solange Volnov, Hamzah Baagil, Oliver Winz, Hans-Juergen Kaiser, Sanne Katherina Meles, Joerg Bernhard Schulz, Kathrin Reetz, Felix Manuel Mottaghy, Florian Holtbernd

“…The ET related metabolic spatial covariance pattern (ETRP) was characterized by relatively increased metabolism in the cerebellum, brainstem, and temporo-occipital cortices, accompanied by relative metabolic decreases mainly in fronto-temporal and motor cortices. …”
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ZYGOMYCOSIS IN IMMUNOCOMPROMISED NON-HAEMATOLOGICAL PATIENTS by George Petrikkos, Miranda Drogari-Apiranthitou

“…Suspicion index can be increased through recognition of the differential patterns of clinical presentation. In the non- haematological immunocompromised patients, zygomycosis can manifest in various clinical forms, depending on the underlying condition: mostly as rhino-orbital or rhino-cerebral in diabetes patients, pulmonary infection in patients with malignancy or solid organ transplantation, disseminated infection in iron overloaded or deferoxamine treated patients, cerebral - with no sinus involvement - in ID users, gastrointestinal in premature infants or malnourishment, and cutaneous after direct inoculation in immunocompetent individuals with trauma or burns. …”
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Dynamic electro‐clinical features in Guanidinoacetate N‐methyltransferase deficiency: A familial case series by Mariapaola Schifino, Emanuele Bartolini, Stefano Pagano, Camilla Meossi, Rosa Pasquariello, Roberta Battini

“…The older two had seizures that improved with treatment, but their brain activity remained abnormal. The youngest, diagnosed and treated earlier with supplementation, did not develop epilepsy. …”
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Evaluation of some photosensitizers against the cotton leaf worm, Spodoptera littoralis (Lepidoptera: Noctuidae), in relation to spectral and thermal reflectance by M. S. Yones, Shireen A. M. Maamoun, Abd El Aziz A. Khidr, Mahmoud Sayed, Hend A. A. Al-Ashry, Radwa G. Attia

“…Larvae fed on photosensitizing compounds showed distinct spectral reflectance patterns. Treated larvae had same reflectance manner; which were higher than that of control samples. …”
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