Changes in CD and Correlation with Hepatic Insulin Resistance Index and Triacylglycerol 36 Level in Liver of Malarial Infected Mice Treated with Phyllanthus amarus

“…The control and chloroquine treated groups produced similar correlation pattern, but those for the extract-treated were weaker. …”
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Randomized clinical trial to evaluate the effectiveness of different thicknesses of stabilization splints in treating temporomandibular disorder using joint vibration analysis as a... by Jyoti Sharma, Rajlakshmi Banerjee, Vijeta Gajbhiye, Anushree Bhoge, Priti Jaiswal, Kiran Nayak

“…JVA analyzed these vibrations to detect internal joint abnormalities, and their patterns were further categorized using the Piper classification was highly accurate and hence used over magnetic resonance imaging. …”
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Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats by Yaoyao Zhu, Ge Lu, Weixin Li, Chenchen Su, Pengfei Du, Shuyou Wang, Li Yang, Huanfang Xu, Yigong Fang, Xiaojing Song

“…In addition, we investigated the ovarian functional changes post-ISF obstruction and evaluated the therapeutic effects of acupuncture on ovarian dysfunction in aged rats, both in unblocked and ISF-blockade conditions.ResultsFluorescence imaging revealed ISF transport along the linea alba, with tracers migrating linearly, a pattern abolished by surgical blockade. Abnormal ISF transport in the linea alba may affect the homeostasis of reproductive hormone levels. …”
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Can Emotional and Behavioral Dysregulation in Youth Be Decoded from Functional Neuroimaging? by Liana C L Portugal, Maria João Rosa, Anil Rao, Genna Bebko, Michele A Bertocci, Amanda K Hinze, Lisa Bonar, Jorge R C Almeida, Susan B Perlman, Amelia Versace, Claudiu Schirda, Michael Travis, Mary Kay Gill, Christine Demeter, Vaibhav A Diwadkar, Gary Ciuffetelli, Eric Rodriguez, Erika E Forbes, Jeffrey L Sunshine, Scott K Holland, Robert A Kowatch, Boris Birmaher, David Axelson, Sarah M Horwitz, Eugene L Arnold, Mary A Fristad, Eric A Youngstrom, Robert L Findling, Mirtes Pereira, Leticia Oliveira, Mary L Phillips, Janaina Mourao-Miranda

“…We aimed to use functional neuroimaging and pattern regression techniques to determine whether patterns of brain activity could accurately decode individual-level severity on a dimensional scale measuring behavioural and emotional dysregulation at two different time points.…”
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Multiomics reveals metformin’s dual role in gut microbiome remodeling and hepatic metabolic reprogramming for MAFLD intervention by Yuan-dong Sun, Hao Zhang, Xiao-long Gong, Yuan-min Li, Ruiqin Han, Chun-xiao Zhou, Jian-jun Han

“…Metabolomic and lipidomic analyses revealed that metformin corrected abnormal lipid metabolism patterns, reduced hepatic fat deposition, and influenced key metabolic pathways associated with MAFLD progression. …”
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BERT-based network for intrusion detection system by Yong Yang, Xing Peng

“…By treating network traffic as a “language,” our approach resolves issues that traditional methods struggle with while being scalable and adaptable to various network environments and attack patterns.…”
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Heart Failure with Preserved Left Ventricular Ejection Fraction: A Complex Conundrum Simply Not Limited to Diastolic Dysfunction by Angel Lopez-Candales, Talal Asif, Khalid Sawalha, Nicholas B. Norgard

“…Over the last two decades, the changing paradigm of heart failure with preserved ejection fraction (HFpEF) has transformed our understanding not only of the pathophysiology of this clinical entity but also the diagnostic and therapeutic approaches aimed at treating this complex patient population. No longer HFpEF should be seen as simply left ventricular diastolic dysfunction but as a group of that in addition of having small and thick left ventricles with abnormal diastolic filling patterns as their main pathophysiologic abnormality; they also have whole host of different abnormalities. …”
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Histological profiling of the extracellular matrix of streptozotocin-induced diabetic nephropathy in experimental mice and rats, an analytical study by Anas K. Al Makhzoomi

“…Diabetic nephropathy (DN) is characterized by dysfunction and a complication of the extracellular matrix (ECM) with an abnormal pattern of Glycosaminoglycan (GAG) synthesis. …”
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Derotational osteotomy is a relevant procedure in the management of lateral patellar dislocation: An expert survey of the International Patellofemoral Study Group by Guido Wierer, Danko Milinkovic, Gerd Seitlinger, Michael Liebensteiner, William Post, Philipp W. Winkler

“…The most important factors for performing derotational osteotomy are abnormal torsion (100%), abnormal gait pattern (57%), revision cases (74%) and recurrent patellar instability (61%). …”
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The Efficacy and Brain Network Mechanism of Acupuncture for Knee Osteoarthritis: A Study Protocol for Randomized Controlled Neuroimaging Trial by Sun YY, Wang ML, Zhao RH, Hao MY, Song S, Zhou Y, Zhang N

“…Therefore, this study uses KOA as the research vehicle, focuses on the abnormal connectivity patterns of brain functional networks, and integrates clinical pain assessments to thoroughly investigate the central mechanisms of acupuncture therapeutic effects on KOA.Patients and Methods: In this parallel, randomized, sham-controlled neuroimaging trial, 60 KOA patients will be randomly divided into the acupuncture group and sham acupuncture group in a 1:1 ratio, treated three times weekly for a total of 12 sessions. …”
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Biomechanical analysis of elastic fixation for lisfranc injuries with finite elements method by Yang Liu, Wen Lu, Wei Liu, Wang-sheng Wu, Cheng-wei Wang

“…Nonetheless, each pretension level exhibited a unique stress distribution pattern. At 70 N of pretension, elastic fixation achieved biomechanical stability comparable to that of the normal foot model. …”
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Deconvolution of serum cortisol levels by using compressed sensing. by Rose T Faghih, Munther A Dahleh, Gail K Adler, Elizabeth B Klerman, Emery N Brown

“…Identification of the amplitude and timing of pulsatile hormone release allows (i) quantifying of normal and abnormal secretion patterns towards the goal of understanding pathological neuroendocrine states, and (ii) potentially designing optimal approaches for treating hormonal disorders.…”
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Psychological stress dysfunction in women with premenstrual syndrome by Qing Liu, Yuhang Lin, Wenjuan Zhang

“…Despite its prevalence, the neural mechanisms underlying PMS—particularly those related to stress—are not fully understood.This review aims to explore the complex interactions between PMS and stress, with a focus on the hormonal pathways involved. We propose that abnormal stress coping styles and stress reactivity patterns, collectively referred to as stress dysfunction, are crucial factors influencing women's vulnerability to PMS. …”
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Use of Basket Trials to Solve Sleep Problems in Patients with Rare Diseases by Lara C. Pullen, Nick Bott, Cate McCanless, Amee Revana, Gunes Sevinc, Casey Gorman, Alexandra Duncan, Sarah Poliquin, Anna C. Pfalzer, Katie Q. Schmidt, E. Robert Wassman, Chère Chapman, Maria Picone

“…Food and Drug Administration regarding abnormal sleep patterns in various rare diseases. Last, in response to the profound unmet medical needs of patients with rare diseases and sleep disorders, we propose adapting and using the clinical trial design known as a “basket trial”. …”
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Harnessing lipid metabolism modulation for improved immunotherapy outcomes in lung adenocarcinoma by Yu Chen, Yang Chen, Yu Zhou, Yongsheng Li, Ran Ren, Juan Lei

“…Recent research suggests that abnormal lipid metabolism in patients with lung adenocarcinoma may hinder the efficacy of anti-PD-1 monotherapy.Methods Here, we delved into the patterns of lipid metabolism in patients with The Cancer Genome Atlas (TCGA)-lung adenocarcinoma (LUAD) and their correlation with the immune microenvironment’s cellular infiltration characteristics of the tumor. …”
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Adipose-derived stem cells alleviate acute pancreatitis by inhibiting ferroptosis and oxidative damage in canines by Yansong Ge, Mingzhen Chen, Meilin Li, Zheng Wang, Ruxin Ding, Zhiying Wan, Enshuang Xu, Jiasan Zheng

“…ADSCs (1 × 106/kg) and CM (0.1 mL/kg) were injected intravenously 6 h after surgery, and the roles on ferroptosis and oxidative stress were analyzed. The changing patterns of ferroptosis and oxidative stress were determined in vitro using a lipopolysaccharideinduced cellular inflammation model of AR42J. …”
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An approach to arousal disorder classification using deformable convolution and adaptive multiscale features in EEG signals by Andia Foroughi, Fardad Farokhi, Fereidoun Nowshiravan Rahatabad, Alireza Kashaninia

“…Our proposed model, a hierarchical multiscale deformable attention module, excels at detecting complex and abnormal patterns in EEG data. We apply this model after segmenting EEG data into 30-second windows and generating spectrogram images. …”
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Adolescent scoliosis in autism spectrum disorder: is it idiopathic or syndromic?? by Ravi Rajendra, Matthew B. Bratton, Claudia Leonardi, R. Carter Clement

“…Our study at a high-volume scoliosis center compares patterns of scoliosis in ASD patients with those of neurotypical patients. …”
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Combined Transcriptome Analysis Reveals the Mechanism of ‘Shine Muscat’ Pollen Abortion Induced by CPPU and TDZ Treatment by Mengfan Ren, Yixu Wang, Siyi Yi, Jingyi Chen, Wen Zhang, Haoran Li, Ke Du, Jianmin Tao, Huan Zheng

“…CK), 16 DEGs exhibited similar expression patterns. Further tissue-specific expression analysis identified nine genes that were highly expressed in stamens and shared the same expression pattern in sterile lines. …”
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The sexually dimorphic expression of glutamate transporters and their implication in pain after spinal cord injury by Jennifer M. Colón-Mercado, Aranza I. Torrado-Tapias, Iris K. Salgado, José M. Santiago, Samuel E. Ocasio Rivera, Dina P. Bracho-Rincon, Luis H. Pagan Rivera, Jorge D. Miranda

“…The dimorphic expression revealed in this study provides a therapeutic opportunity for treating chronic pain, an area with a critical need for treatment.…”
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