Clinical Molecular Immunohistochemistry Mismatch Repair Mutations in Lynch Syndrome in Patients Under 50 Years: A Systematic Review by Bogdan Adrian Manta, Adrian Cosmin Ilie, Felicia Marc, Daciana Nistor, Patricia Octavia Mazilu, Claudia Borza

“…Data extraction covered demographic details, number of patients tested, proportion with abnormal IHC, frequency of somatic or germline MMR gene mutations, and method of classification into sporadic dMMR vs. …”
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Traumatic knee injuries and career drop-outs in adolescent competitive alpine skiers aged 15–19: a longitudinal 4-year follow-up study examining rates, biomechanical injury risk fa... by Jonas Hanimann, Daniel P. Fitze, Thomas Koller, Flavia Schürmann, Stefan Fröhlich, Georg C. Feuerriegel, Christoph Stern, Johannes Scherr, Eling D. de Bruin, Reto Sutter, Jörg Spörri

“…Introduction The aims of this longitudinal 4-year follow-up study were (1) to assess traumatic knee injuries and career drop-out rates in competitive alpine skiers from mid- to late adolescence (i.e. 15–19 years), (2) to investigate the magnetic resonance imaging (MRI) abnormalities in the knees of skiers reaching late adolescence, and (3) to evaluate the biomechanical landing patterns of mid adolescent skiers and to compare skiers who experienced an anterior cruciate ligament (ACL) injury during the 4-years follow-up and those who did not.Materials and methods At baseline, knee flexion angle and medial knee displacement during drop jump landing were biomechanically assessed in 108 skiers aged 14.83 ± 0.58 years. …”
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The Fetus Points to the Diagnosis of Rare Skeletal Dysplasia: Stuve–wiedemann Syndrome: Retrospective Case Series and Prenatal Review by Muzibunnisa A Begam, Muhammad Hasan, Fares Chedid, Hisham Mirghani

“…The consistent findings that helped in reaching the suspicion were the typical pattern of long bone involvement (bowing of tibia > femora, relative sparing of the fibula and upper limb bones, normal scapulae, and clavicles), and the presence of camptodactyly. …”
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Clinical Applications of Hyperpolarised Xenon-129 MRI by Kher Lik Ng, James Grist, Fergus Gleeson, Emily Fraser

“…The role of HPX-MRI in respiratory medicine has the potential to be wide-reaching, but to date it remains largely a research tool. …”
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Factors leading to the high frequency of western North Pacific tropical cyclones in late autumn 2024 by Fang-Ching Chien, Yen-Chao Chiu

“…Spatially, LA24 TCs displayed a pronounced clustering pattern, with all systems forming at similar latitudes east of the Philippines. …”
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A case study of extreme rainstorm in northern Xinjiang under the influence of large-scale circulation and topography by Jiangang Li, Jiangang Li, Jiangang Li, Jiangang Li, Boyuan Li, Cailian Jiang, Yufei Jiang, Yufei Jiang, Yufei Jiang, Yufei Jiang, Jinru Zhang, Jinru Zhang, Jinru Zhang, Jinru Zhang, Lianmei Yang, Lianmei Yang, Lianmei Yang, Lianmei Yang, Na Li

“…Stable synoptic systems enabled significant water vapor to reach the heavy rainfall area in advance. The western boundary contributed to full-layer water vapor input, while the southern boundary provided mid-to-upper-level input, leading to increased water vapor flux, enhanced convergence, and prolonged saturation. …”
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Chemogenetic tools for modulation of spatial learning in dopamine transporter deficient rats by Arina A. Gromova, Arina A. Gromova, Taisiia S. Shemiakova, Mikhail G. Khotin, Evgeniia N. Petrunina, Anastasia D. Belskaya, Raul R. Gainetdinov, Raul R. Gainetdinov, Natalia P. Kurzina, Anna B. Volnova, Anna B. Volnova

“…Variables such as the distance traveled, time taken to reach the goal box, number of errors and the perseverative patterns of activity were analyzed.ResultsNorepinephrine release from the LC to the PFC reduced hyperactive behavioral patterns in rats lacking the dopamine transporter (DAT-KO rats) with spontaneously elevated dopamine transmission. …”
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Prevention of fetal brain injury in category II tracings by Masahiro Nakao, Michael G. Ross, Shoichi Magawa, Satoshi Toyokawa, Kiyotake Ichizuka, Naohiro Kanayama, Shoji Satoh, Nanako Tamiya, Akihito Nakai, Keiya Fujimori, Tsugio Maeda, Akira Oka, Hideaki Suzuki, Mitsutoshi Iwashita, Tomoaki Ikeda

“…Cases included those presumed to have an intrapartum onset of hypoxic–ischemic insult based on the fetal heart rate pattern evolution from reassuring to an abnormal pattern during delivery, in association with category II tracings marked by recurrent decelerations and an umbilical arterial BDecf ≥ 12 mEq/L. …”
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Early Postural Instability in Parkinson’s Disease: A Biomechanical Analysis of the Pull Test by Javier Ricardo Pérez-Sánchez, Francisco Grandas

“…We performed a multimodal approach that included a systematic analysis of the pull force needed to reach the backward limit of stability (FBLoS) assessed by mechanically produced forces, the displacements of the center of pressure (CoP) recorded on a force platform, and the latencies and patterns of activation of the stabilizing muscles. …”
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ANALYSIS OF THE GINGIVAL RECESSION PREVALENCE AMONG DENTAL PATIENTS CONSIDERING ASSOCIATED AGE-RELATED, IATROGENIC AND PATHOLOGICAL CHANGES OF DENTAL STATUS by O.A. Krasnokutskyy, P.A. Hasiuk, M.Y. Goncharuk-Khomyn

“…Patients aged 30 years and older, male, and those with clinical signs of periodontitis, pathological attrition, non-carious and carious cervical lesions, poor oral hygiene, overcrowding of teeth, abnormalities of teeth position and abnormal attachment of mucous membranes could be categorized as those having potential risk for further recession development. …”
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SUBCLINICAL INTERSTITIAL PULMONARY INJURY IN RHEUMATOID ARTHRITIS by D. V. Bestaev, L. A. Bozhyeva, A. V. Volkov, A. A. Novikov, S. I. Glukhova, E. L. Nasonov

“…Nasonova Research Institute of Rheumatology; in so doing, high-resolution computed tomography revealed lung changes as a ground glass pattern in 15 patients, reticular striation, traction bronchoectases, and lung tissue changes as honeycomb ones in 25 patients; no lung abnormalities were found in 21 patients. …”
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Assessment of Behavioral disorders of children with Autism by Kawther S. Dawood, Ali K. Khudhair

“…The highest percentage of children reported a moderate level of the impairment in social interaction, behavioral pattern problems, sensory responses abnormalities and lack of emotional responses. …”
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Evaluation of ciliary functions and ciliary beat frequency via cell culture method in patients with primary ciliary dyskinesia by Nagehan Emiralioğlu, Nural Kiper, Deniz Doğru, Ebru Yalçın, Mina Gharibzadeh Hızal, Sanem Eryılmaz Polat, Gökçen Dilşa Tuğcu, Önder Günaydın, Pergin Atilla, Elif Bilgiç, Bengisu Kaya, Rümeysa Hekimoğlu, Uğur Özçelik

“…This study showed us that there was no difference between cilia beat frequency and beat pattern before and after cell culture in patients with definitive diagnosis of PCD and repeated HSVM would be a useful diagnostic approach in patients who have no possibility to reach other diagnostic methods. …”
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The uterine cavity state in older reproductive age patients by V. N. Lokshin, A. N. Rybina, A. T. Abshekenova, E. Askar, Sh. K. Karibaeva, R. K. Valiev

“…Common endometrial abnormalities included fibrosis, stromal sclerosis, lymphocytic infiltration, polyps, hypoplasia, hyperplasia, and mixed lesions.Conclusion. …”
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