Efficacy of non-wearable VR-based behavioral training for preschool children with high-functioning autism spectrum disorder: a protocol for an upcoming randomized clinical trial by Naichi Kuo, Yukai Yao, Chenhuan Ma, Liting Chu, Jinjin Chen, Chunling Wan, Dandan Wang, Dingjie Lu, Xiaoqian Li, Yu Wang

“…Virtual reality (VR) is a promising digital rehabilitation tool that may support the development of essential life skills, such as social communication and daily living abilities, in many children and adolescents with ASD. …”
Get full text

Hypobaric hypoxia aggravates neuroinflammation in ligature-induced periodontitis mice via the STAT3 signaling pathway by Lu Chen, Lu Chen, Jiayi Zhang, Xuechao Fei, Jiajing Wang, Jiayue Gao, Xiangpei Yue, Yaqun Jiang, Yaqun Jiang, Zibi Shi, Shaojie Zhang, Xiufang Jiang, Wenyue Chang, Zhonghua Dai, Jianjun Guo, Tong Zhao, Xiaoxia Jiang, Lingling Zhu, Lingling Zhu

“…Background and purposeStudies have shown that inflammation is a key risk factor for altitude sickness in hypobaric hypoxia environments. …”
Get full text

Low electric field‐driven and fast‐moving relaxor ferroelectric soft robots by Longchao Huang, Weili Deng, Guo Tian, Yue Sun, Tao Yang, Boling Lan, Xuelan Li, Yang Liu, Tianpei Xu, Shenglong Wang, Yong Ao, Jieling Zhang, Long Jin, Weiqing Yang

“…Moreover, the developed robot demonstrates remarkable abilities in climbing slopes and carrying heavy loads. …”
Get full text

Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice by Xin Wang, Wei Wu, Guang Yang, Xue-Wei Yang, Xu Ma, Dan-Dan Zhu, Kabir Ahmad, Khizar Khan, Ying-Zi Wang, Ao-Ran Sui, Song-Yu Guo, Yue Kong, Bo Yuan, Tian-Yuan Luo, Cheng-Kang Liu, Peng Zhang, Yue Zhang, Qi-Fa Li, Bin Wang, Qiong Wu, Xue-Fei Wu, Zhi-Cheng Xiao, Quan-Hong Ma, Shao Li

“…Methods: A mouse model for astrocytic Nav1.6 knockdown was constructed to study the effects of astrocytic Nav1.6 on amyloidosis. …”
Get full text

Presenting the conceptual model of organizational democracy with an emphasis on the development of employees' psychological capital by Sattar jahantabi neghad, Foad Makvandi, ezat allah Kiani, ghanbar Amirnegad, Vahid Chenari

“…Aghajanpour et al, (2022) conducted a study titled "Designing a multi-voice organizational model in Iran's higher education". …”
Get full text

Oryzalin-Induced polyploidy enhances natural metabolite accumulation and functional bioactivities in novel Callisia fragrans genotype by Neha Gupta, Soham Bhattacharya, Jana Žiarovská, Adrish Dutta, Veronika Fialková, Silvia Farkasová, Anna Mascellani Bergo, Jaroslav Havlik, Jan Tauchen, Pavel Novy, Klára Urbanová, Luigi Milella, Eloy Fernández-Cusimamani

“…Synthetic polyploidization using oryzalin was conducted to obtain high-quality cultivars of C. fragrans, facilitating enhanced phenotypic and biological traits without genetic modification. This study aimed to explore the metabolic spectrum and biological activities of oryzalin-induced polyploid C. fragrans for its advanced medicinal application. …”
Get full text

Effects of a wearable hand orthosis on upper and lower limb motor recovery in stroke patients: a randomized controlled trial by Lijuan Xu, Jie Zhang, Qiang Liu, Yefan Cao, Nazhakaiti Aizezi, Jing Tian, Cheng Wu, Liyu Fang, Liyi Chen, Yanzheng Zhang, Xueming Pang, Yanli Lin, Jingxin Wang, Hewei Wang

“…ObjectiveOrthoses have shown potential in addressing upper limb spasticity in stroke survivors; however, their influence on motor recovery remains controversial. This study aimed to examine the effects of a wearable hand orthosis on spasticity, motor recovery of both upper and lower limbs, balance, and activities of daily living in stroke.DesignRandomized controlled trial.SettingInpatient rehabilitation department.ParticipantsFifty-one stroke survivors with hemiplegia were randomly assigned to either an experimental group (n = 26) or a control group (n = 25).InterventionsBoth groups underwent a 4-week conventional rehabilitation program. …”
Get full text

Performance on the Rey-Osterrieth complex figure test and the correlation with the magnetic resonance imaging brain lesion volume in multi-infract versus small vessel disease demen... by Semnić Marija D., Semnić Robert, Nikolašević Željka, Bugarski-Ignjatović Vojislava V., Vujanić-Stankov Tijana Ž., Kostić Smiljana, Ocić Gordana, Kozić Duško

“…Regarding several cognitive domains, including visuospatial and visuoconstructional abilities, little is known about the differences between vascular dementia (VaD) subtypes, even in the most common sub-types, such as multi-infarct dementia (MID) and subcortical ischemic small vessel disease dementia (SSVD). …”
Get full text

Effect of environmentally relevant concentrations of estrogens on the aggressive response of male zebrafish by Ying–Ying Zhang, Ying–Ying Zhang, Hong Tao, Hong Tao, Yan–Jun Shen, Yan–Jun Shen, Qi–Liang Chen, Qi–Liang Chen, Zhi–Hao Liu, Zhi–Hao Liu

“…Environmental estrogens (EEs) are diverse and widespread in aquatic systems, influencing fish social behaviour. Prior studies have focused on individual EEs, but their combined effects, particularly at environmentally relevant concentrations, remain underexplored. …”
Get full text

A high clinically translatable strategy to anti-aging using hyaluronic acid and silk fibroin co-crosslinked hydrogels as dermal regenerative fillers by Jialing Cheng, Zhiyang Chen, Demin Lin, Yanfang Yang, Yanjing Bai, Lingshuang Wang, Jie Li, Yuchen Wang, Hongliang Wang, Youbai Chen, Jun Ye, Yuling Liu

“…Based on a complementary strategy, this study combines the rapid gelling properties of HA with the collagen regenerative properties of SF to create a co-crosslinked HA-SF hydrogel. …”
Get full text

DNAJC24 suppresses breast cancer malignancy and serves as a prognostic biomarker by Wenjing Meng, Wei Liu, Yulong Yang, Xiaorui Wang, Linlin Zhan, Yi Luo, Liwei Chen, Yu Wang, Guangtao Li, Yehui Shi, Yuchao He, Zhongsheng Tong, Hua Guo

“…Overexpression of DNAJC24 in breast cancer cells significantly reduced colony formation (p < 0.05), proliferation rates, chemotaxis (p < 0.05), invasion (p < 0.05), and migration abilities (p < 0.05) compared to controls. Conversely, DNAJC24 knockdown in cancer cells produced opposite effects, significantly enhancing chemotaxis, invasion, and migration (all p < 0.05). …”
Get full text

Altered Functional Connectivity in Acute Ischemic Post-Stroke Non-Fluent Aphasia Based on fMRI-EEG Multimodal Fusion by Juehan Wang, Lin Mao, Hang Zhou, Shuang Wei, Tianfang Zhang, Haijun Li, Lingmei Ni, Shuyi Pan, Dazhi Guo, Daming Wang, Zuobing Chen

“…This study examined alterations in resting-state and task-state functional connectivity (FC) in patients with acute ischemic post-stroke nonfluent aphasia, using a combined resting-state functional magnetic resonance imaging and visuospatial working memory electroencephalography methodology. …”
Get full text

Effect of injecting adipose stem cells combined with platelet-rich fibrin releasate at Shenshu acupoint (BL23) on acute kidney injury in rabbits by Hsin-Ni Chuang, Wen Pei, Tzong-Fu Kuo, Yu-Hao Liu, Chia-Yih Wang, Yen-Wei Chang, Chi‐Hsuan Chuang, Chang-Huan Yang, Ming-Hsi Chuang, Ming-Hsi Chuang, Ming-Hsi Chuang, Ming-Hsi Chuang

“…Adipose-derived stem cells (ADSCs) are known for their regenerative, differentiative, and repair abilities, making them a promising therapeutic option for kidney injury. …”
Get full text

Long non-coding RNA MIR22HG impedes the progression of anaplastic thyroid carcinoma via targeting miR-141-3p/PTEN/AKT axis by Junyu Cao, Peng Jiang, Songliang Jiang, Yuhan Zhao, Xin Jiang, Chuancheng Zhou, Jing Li, Kunxian Yang

“…Nevertheless, little is known about the potential role of MIR22HG in ATC. In this study, we aimed to investigate the biological functions and underlying molecular mechanisms of MIR22HG in ATC. …”
Get full text

Genomic Insights into Plant Growth-Promoting Traits of <i>Lysinibacillus fusiformis</i> and <i>Bacillus cereus</i> from Rice Fields in Panama by Celestino Aguilar, Rito Herrera, José L. Causadías, Betzaida Bernal, Oris Chavarria, Claudia González, Jessica Gondola, Ambar Moreno, Alexander A. Martínez

“…This work offers new insights into the genomic basis of the studied strains’ plant growth-promoting capabilities.…”
Get full text

Bone Marrow Stem Cell Population in Single- and Multiple-Level Aspiration by Xiangguo Che, Hee-June Kim, Xian Jin, Joon-Woo Kim, Kyeong-Hyeon Park, Jeong-Ok Lim, Hee-Soo Kyung, Chang-Wug Oh, Je-Yong Choi

“…In the process of osteoblast differentiation, it was observed that MSCs exhibited more advanced features of enhanced osteoblastic abilities in the single-level method rather than the multiple-level method. …”
Get full text

Response Patterns of Three Types of Biocrust to Reduced Rainfall by Hongyu Jiang, Qianhai Ye, Siqing Wang, Liping Yang, Yali Ma, Yuhan Qi, Haoran Luo, Zhixin Zhou, Qinqin Chang, Li Ma, Hao Wang, Changming Zhao, Ning Chen

“…Soil water content might mediate the impacts of the rainfall regime on moss biocrust cover but not on algae and lichen biocrust cover. This study offers a comprehensive evaluation of the overall response of 3 biocrust types to reduced rainfall, thereby enhancing our abilities to mitigate climate change in dryland ecosystems.…”
Get full text

A model for the cognitive assessment of physicians by Victor A. Del Bene, Victor A. Del Bene, George Howard, David S. Geldmacher, Elizabeth Turnipseed, Catherine Brown, Catherine Brown, Kathleen Lowry, Trevor Starling, Kate Bryan, T. Charles Fry, Keith A. Jones, Keith A. Jones, Keith A. Jones, Ronald M. Lazar, Ronald M. Lazar

“…Our objective was to develop a normative database of healthy physicians that can be used in physician competency evaluations.MethodsThis study was a prospective cross-sectional observation design. …”
Get full text

Resting-state EEG network variability predicts individual working memory behavior by Chunli Chen, Shiyun Xu, Jixuan Zhou, Chanlin Yi, Liang Yu, Dezhong Yao, Yangsong Zhang, Fali Li, Peng Xu

“…However, the relationship between the temporal variability of resting-state networks and working memory (WM) remains largely unexplored. This study aims to address this gap by employing an EEG-based protocol combined with fuzzy entropy. …”
Get full text

IFN-γ licenses normal and pathogenic ALPK1/TIFA pathway in human monocytes by Amandine Martin, Solène Caron, Mélissa Marcotte, Pauline Bronnec, Etienne Garneret, Nora Martel, Georgina Maalouf, Pascal Sève, David Saadoun, Yvan Jamilloux, Thomas Henry

“…Specific mutations in ALPK1 are associated with an autoinflammatory syndrome termed ROSAH and with spiradenoma (skin cancers with sweat gland differentiation). This study investigated ALPK1 responses in human mononuclear cells and demonstrates that human mononuclear cells have distinct abilities to respond to ADP-heptose. …”
Get full text