Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients. by Laura Breda, Carla Casu, Sara Gardenghi, Nicoletta Bianchi, Luca Cartegni, Mohandas Narla, Karina Yazdanbakhsh, Marco Musso, Deepa Manwani, Jane Little, Lawrence B Gardner, Dorothy A Kleinert, Eugenia Prus, Eitan Fibach, Robert W Grady, Patricia J Giardina, Roberto Gambari, Stefano Rivella

“…However, previous studies have not addressed whether the ability of lentiviral vectors to increase hemoglobin synthesis might vary in different patients.We generated lentiviral vectors carrying the human β-globin gene with and without an ankyrin insulator and compared their ability to induce hemoglobin synthesis in vitro and in thalassemic mice. …”
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The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence. by Delma S Childers, Ingrida Raziunaite, Gabriela Mol Avelar, Joanna Mackie, Susan Budge, David Stead, Neil A R Gow, Megan D Lenardon, Elizabeth R Ballou, Donna M MacCallum, Alistair J P Brown

“…Efficient carbon assimilation is critical for microbial growth and pathogenesis. …”
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‌Rockburst intensity grading prediction based on the LOF-ENN-KNN model‌ by Haoran Ge, Jiyong Zhang, Congbo Ma, Kai Hui, Yicong Li, Ziniu Wu

“…Through engineering examples, it is further confirmed that high-precision prediction ability can still be preserved in complex nonlinear parameters, which provides an efficient and reliable technical scheme for rockburst warning in deep engineering.…”
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Progress on plant-microorganism combined remediation of organic pollutants by HUANG Junwei, CHUANG Shaochuang, CHEN Kai, LING Wanting, TANG Xiangyu, JIANG Jiandong

“…Examples include that the interaction of alfalfa and soil microbe can greatly reduce the concentration of PCBs in soil, and the inoculation of rhizobium and mycorrhizal fungi enhances the ability of alfalfa to remove PCBs. Regarding the problems raised in the development of bioremediation, the following three aspects should be emphasized in the study of plant-microorganism remediation in the future: 1) Screen selected microbial strains and plant materials to improve the remediation efficiency of microbe and resistance of plants; 2) strengthen the real-time monitoring ability of bioremediation process of organic pollutants, optimize and control the living environment of plants and microorganisms, and improve the efficiency of remediation; 3) improve the degradation efficiency by enhancing the bioavailability of pollutants to strengthen the bioremediation effect.…”
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Developing risk models for predicting incidence of diabetes and prediabetes in the first-degree relatives of Iranian patients with type 2 diabetes and comparison with the finnish d... by Parisa Khodabandeh Shahraki, Awat Feizi, Sima Aminorroaya, Heshmatollah Ghanbari, Majid Abyar, Massoud Amini, Ashraf Aminorroaya

“…The predictive ability of developed models was higher than FPG and HbA1c; however, it was comparable with OGTT-AUC alone. …”
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Based on BERT-GPT-GNN converged architecture: intelligent generation engine for complex SQL queries in business intelligence by Shiwei Chu, Jie Liu

“…The text2SQL business intelligence system based on RAG proposed in this article significantly improves the ability to process complex queries and reduces data access barriers, thereby providing enterprise users with more convenient and efficient database query tools.…”
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Tuning the Mutual Synchronization of Electrically Coupled Spin‐Torque Oscillators by Selecting the Vortex Dynamic Regime by Miguel Romera, Philippe Talatchian, Steffen Wittrock, Romain Lebrun, Karla J. Merazzo, Paolo Bortolotti, Laurent Vila, Ricardo Ferreira, Marie Claire Cyrille, Ursula Ebels, Vincent Cros, Julie Grollier

“…By slightly tuning the injected dc current, this transition regime, which is highly efficient at synchronization, evolves into a dynamic state with no ability to synchronize. …”
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End-to-end deep-learning model for the detection of coronary artery stenosis on coronary CT images by Truls Råmunddal, Naveed Sattar, Erik Andersson, Kristofer Skoglund, Araz Rawshani, Göran Bergström, Deepak L Bhatt, Elmir Omerovic, Oskar Angerås, Bjorn Redfors, Jan Borén, Petur Petursson, Aidin Rawshani, Lukas Hilgendorf, Vibha Gupta, Gustav Smith, Carlo Pirazzi

“…Decision curve analysis and net reclassification index assessments reinforced the efficacy of EfficientNet models, confirming their superior diagnostic capabilities.Conclusion Our end-to-end deep-learning model demonstrates, for the LAD artery, excellent discriminatory ability and calibration during internal validation, despite a small dataset used to train the network. …”
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Resource Allocation With Edge-Cloud Collaborative Traffic Prediction in Integrated Radio and Optical Networks by Bowen Bao, Hui Yang, Qiuyan Yao, Lin Guan, Jie Zhang, Mohamed Cheriet

“…To pursue efficient integrated radio and optical networks, more efficient ways to conduct transmission under the demand of edge and cloud collaboration are required. …”
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(IoT) Network intrusion detection system using optimization algorithms by Luo Shan

“…WOA’s spiral bubble-net search strategy endows the model with efficient global optimization in large-scale feature spaces, while GWO’s hunting behavior, based on a social hierarchy, enhances fine-tuned optimization in key feature regions. …”
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Research on Real Time Data Processing and Application of Urban Rail Train by ZENG Gaoping, WANG Lei

“…The application platform uses real-time data of train to realize train-related demand functions, and effectively converts the data into actual business form, thereby improves the ability of personnel to perceive the running status of vehicle, reducing workload of artificial maintenance and operation, and ensuring the train high-quality operations.…”
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Biochemical evaluation of molecular parts for flavonoid production using plant synthetic biology by Hyo Lee, Saet Buyl Lee, Sangkyu Park, Jaeeun Song, Beom-Gi Kim

“…Among organisms on Earth, plants have the unique ability to produce a wide variety of biomolecules using soil nutrients, air, and solar energy. …”
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Binary Tree Blockchain of Decomposed Transactions by Davut Çulha

“…Binary trees offer several advantages, such as the ability to address nodes with binary numbers, providing a straightforward and efficient method for identifying and locating nodes. …”
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Intelligent text analysis for effective evaluation of english Language teaching based on deep learning by Yuan Ren, Wenjuan Fan, Jinhai Wang

“…Abstract With the growing demand for English language teaching, the efficient and accurate evaluation of students’ writing ability has become a key focus in English education. …”
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Reaching new frontiers in nanoelectronics through artificial intelligence by Santhosh Sivasubramani, Themis Prodromakis

“…Each pillar of this electronics supply chain underscores AI’s ability to accelerate processes, optimize performance, and reduce costs. …”
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Humanitarian logistics: enhancing the engagement of local populations by Allan Sheppard, Peter Tatham, Ron Fisher, Rodney Gapp

“…A number of key differences between the espoused strategies expressed in disaster management legislation and the actual experiences of local people on the ground were identified and, as a result, a conceptual model was developed that, if implemented, would enhance the capacity of local populations to prepare and respond in a more efficient and effective manner. Findings – – Results from the study indicate that the ability of local populations to contribute to the logistic preparation and response processes has been considerably undervalued and underutilised. …”
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Liveness Detection in Computer Vision: Transformer-Based Self-Supervised Learning for Face Anti-Spoofing by Arman Keresh, Pakizar Shamoi

“…We compared the performance of the proposed fine-tuned ViT model using the DINO framework against traditional models, including CNN Model EfficientNet b2, EfficientNet b2 (Noisy Student), and Mobile ViT on the face anti-spoofing task. …”
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Training hybrid neural networks with multimode optical nonlinearities using digital twins by Oguz Ilker, Suter Louis J.E., Hsieh Jih-Liang, Yildirim Mustafa, Dinc Niyazi Ulas, Moser Christophe, Psaltis Demetri

“…The ability to train ever-larger neural networks brings artificial intelligence to the forefront of scientific and technical discoveries. …”
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UML/OCL based design and the transition towards temporal object relational database with bitemporal data by Soumiya Ain El Hayat, Fouad Toufik, Mohamed Bahaj

“…The emergence of temporal database calls for new visual and efficient modeling techniques to facilitate the design of temporal objects. …”
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DNA screening of Drosophila suzukii predators in berry field orchards shows new predatory taxonomical groups. by Sara Sario, Conceição Santos, Fátima Gonçalves, Laura Torres

“…The high number of life cycles per year, its ability to rapidly invade and spread across new habitats, and highly polyphagous nature, makes this a particularly aggressive invasive species, for which efficient control methods are currently lacking. …”
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