Development and application of artificial intelligence follow-up system in patients with coronary heart disease by Liping Zhang, Yanan Chen, Qiao Yang, Lijuan Lu, yishuang Cui, Miao Zhou, Xiaolu Jin, Shiyi Zhang, Xifei He

“…Traditional manual follow-up methods are time-intensive, inefficient, and lack personalization, limiting their ability to address patients’ complex healthcare needs. …”
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同向双螺杆挤出机挤出物料的混合特性研究Mixing characteristics of materials extruded by coaxial twin screw extruder by 夏伟杰1，马亮2，张俊1，申春赟1 XIA Weijie1, MA Liang2, ZHANG Jun1, SHEN Chunyun1

“…The results showed that the common screw had low mixing performance of material and high extrusion efficiency. The meshing block had a positive effect on increasing the maximum shear stress, which could enhance the mixing performance, but reduced the self-cleaning ability. …”
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Chatbot for the Return of Positive Genetic Screening Results for Hereditary Cancer Syndromes: Prompt Engineering Project by Emma Coen, Guilherme Del Fiol, Kimberly A Kaphingst, Emerson Borsato, Jackilen Shannon, Hadley Smith, Aaron Masino, Caitlin G Allen

“…The highest-rated criteria were tone (mean 4.25, SD 0.71) and usability (mean 4.25, SD 0.58), reflecting the chatbot’s ability to communicate effectively and provide a seamless user experience. …”
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U-Net-based VGG19 model for improved facial expression recognition by Xiaohu ZHAO, Jingyi ZHANG, Mingzhi JIAO, Lixun XIE, Lanfei WANG, Weiqing SUN, Di ZHANG

“…The use of feature cropping and stitching techniques allows the model to efficiently integrate multi-scale features, thereby enhancing the robustness and effectiveness of facial expression recognition tasks. …”
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A double network composite hydrogel with enhanced transdermal delivery by ultrasound for endometrial injury repair and fertility recovery by Xin Zhang, Shufang Wang, Siyu Wang, Zeyi Long, Cong Lu, Jianlin Wang, Lijun Yang, Cancan Yao, Bin He, Xihua Chen, Taifeng Zhuang, Xiangbo Xu, Yufeng Zheng

“…In a rat endometrial injury model, the ultrasound cavitation effect was demonstrated to enhance transdermal delivery efficiency, and the ability of CSMA-RC-Zn-PNS to promote endometrial regeneration, anti-fibrosis and fertility restoration was verified. …”
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Impacts of loading thymoquinone to gold or silver nanoparticles on the efficacy of anti-tumor treatments in breast cancer with or without chemotherapeutic cisplatin by Soha Gomaa, Mohamed Nassef, Ahlam Abu-Shafey, Mona Elwan, Asmaa Adwey

“…Our results further revealed that the combined synergistic approach of TQ’s anti-tumor properties, along with the efficient penetration abilities of AuNPs or AgNPs, led to a significant inhibition of the growth of tumor cells in EAC tumor-bearing mice. …”
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Pathway and protein channel engineering of Bacillus subtilis for improved production of desthiobiotin and biotin by Yue Wu, Guang-Qing Du, Dong-Han Ma, Jin-Long Li, Huan Fang, Hui-Na Dong, Zhao-Xia Jin, Da-Wei Zhang

“…Initially, the desthiobiotin (DTB) and biotin synthesis ability of different B. subtilis strains were evaluated to screen for suitable chassis cells. …”
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Strategies for specific multimodal imaging of cancer-associated fibroblasts and applications in theranostics of cancer by Li Wen, Chengxue He, Yanhui Guo, Nina Zhou, Xiangxi Meng, Yuwen Chen, Cheng Ma, Hua Zhu, Zhi Yang, Lei Xia

“…This nanoplatform can perform positron emission tomography (PET), magnetic resonance imaging (MRI) and photoacoustic imaging (PAI) with strong near infrared absorption and metal chelating ability, achieving efficiently targeting accumulation and display long retention in the tumor region. …”
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<i>Polygonatum sibiricum</i> Polysaccharides Extracted with Ultrasound-Assisted Deep Eutectic Solvents Protect L6 Cells Against Oxidative Stress in a Cellular Model of Sarcopenic O... by Chaoqun Sun, Yifan Xu, Hanchen Du, Yan Chen, Wenjie Qu, Menglu He, Zhengyi Liu, Jian Huang, Junsheng Huo, Jiyong Yin, Jing Liu

“…Our previous study demonstrated that ultrasound-assisted deep eutectic solvents (UAE-DESs) significantly improve the extraction efficiency of PsP; however, the antioxidant effect of PsP extracted using UAE-DESs was unexplored. …”
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Novel cancer stem cell-targeted retinoid ZSH-512 impedes colorectal cancer progress via KDM3A-mediated epigenetic reprogramming by Suyao Li, Wenrui Zhao, Quanlin An, Lei Wang, Mengxuan Zhu, Junjie Ni, Xuan Huang, Yudong Jiang, Min Li, Jiayun Hou, Yiyi Yu, Shan Yu, Lai Wei, Heng Jiao, Tianshu Liu, Xin Cao

“…Here, we identified ZSH-512, a novel synthetic retinoid that selectively targets retinoic acid receptor (RAR)γ, demonstrating its ability to effectively inhibit CRC-CSCs and patient-derived organoids (PDOs) in vitro and significantly reduce CSC-mediated tumor formation and liver metastasis in mouse models without noticeable toxicity. …”
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Advanced QT interval analysis in long-term electrocardiography using shape-based clustering and template matching: A novel approach for Holter monitoring by Kaoru Hatano, Tomohiro Takata, Mineki Takechi, Akane Wada, Hirohisa Taniguchi, Yuichi Tamura

“…Current methods, which are often manual or semi-automated, lack consistency and efficiency, underscoring the need for a more reliable and automated approach. …”
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Business Model Innovation through the Expansion of Digital Platforms by Seyed Hamed Vares, Nastaran Haji Heydari, Mohammad Kargar Shouraki, Morteza Hadizadeh

“…This flexibility helps organizations stay competitive and enhances their ability to respond to evolving customer needs and expectations. …”
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Response of photosynthesis to light and CO2 concentration in spring wheat under progressive drought stress by Fei Chen, Kai Zhang, Shuang Yan, Runyuan Wang, Heling Wang, Hong Zhao, Funian Zhao, Yue Qi, Yang Yang, Xingxing Wei, Yurui Tang

“…There were noticeable thresholds for these parameter changes. The ability of spring wheat to utilize light was weakened by progressive drought stress. …”
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Preventing postsurgical colorectal cancer relapse: A hemostatic hydrogel loaded with METTL3 inhibitor for CAR-NK cell therapy by Zilin Tan, Liangjie Tian, Yang Luo, Kexin Ai, Xuehua Zhang, Haitao Yuan, Jinfan Zhou, Guangyao Ye, Shuofei Yang, Ming Zhong, Gaohua Li, Yanan Wang

“…This study aims to elucidate the underlying mechanisms and improve METTL3 inhibition efficiency. We designed an adhesive hemostasis hydrogel loaded with STM2457, a METTL3 inhibitor, aimed at sustained release in the acidic tumor microenvironment. …”
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Development of a novel multi-epitope mRNA vaccine candidate to combat HMPV virus by Shiyang Ma, Fei Zhu, Yizhong Xu, Haicheng Wen, Mingjun Rao, Peipei Zhang, Wenzhong Peng, Yanhui Cui, Hang Yang, Caixia Tan, Jie Chen, Pinhua Pan

“…Besides, we assessed the docking between the vaccine and immune receptors to evaluate its ability to stimulate immune responses, and the dynamic simulation further confirmed that the vaccine can tightly bind with immune receptors, which approved that the construction has the potential to induce strong humoral and cellular immune response. …”
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An improved bacterial single-cell RNA-seq reveals biofilm heterogeneity by Xiaodan Yan, Hebin Liao, Chenyi Wang, Chun Huang, Wei Zhang, Chunming Guo, Yingying Pu

“…This advancement significantly enhances our ability to investigate the intricate heterogeneity within biofilms at unprecedented resolution.…”
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Poly(ionic liquid) functionalization: A general strategy for strong, tough, ionic conductive, and multifunctional polysaccharide hydrogels toward sensors by Xue Yao, Sufeng Zhang, Ning Wei, Liwei Qian, Hao Ding, Jingtao Liu, Wenqi Song, Sergiu Coseri

“…Ingeniously, due to the inherent conductivity, design flexibility, and functional compatibility of the PILs, the hydrogels exhibit high conductivity (6.54 ± 0.17 mS cm−1), self‐healing ability (94.5% ± 2.0% efficiency), antibacterial properties, freezing resistance, water retention, and recyclability. …”
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Co-culturing Bifidobacterium animalis ssp. lactis with Lactobacillus helveticus accelerates its growth and fermentation in milk through metabolic interactions by Zhi Zhong, Fei Sun, Sheng Xu, Jingda Lu, Rui Yang, Lai-Yu Kwok, Yongfu Chen

“…Our results demonstrated that co-culturing the M8 and H9 strains accelerated growth and fermentation efficiency. This enhancement effect is likely attributed to the strong proteolytic ability of the H9 strain, which hydrolyzes casein to produce small molecular peptides, alanine, tyrosine, and other growth-promoting factors. …”
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A novel bacterium-like particles platform displaying antigens by new anchoring proteins induces efficacious immune responses by Lingdi Niu, Lingdi Niu, Mingchun Gao, Hongkun Ren, Xinqi De, Zhigang Jiang, Xinyao Zhou, Runhang Liu, Hai Li, Haoyuan Duan, Chuankun Zhang, Fang Wang, Junwei Ge

“…Bacterium-like particles (BLP) are the peptidoglycan skeleton particles of lactic acid bacteria, which have high safety, mucosal delivery efficiency, and adjuvant effect. It has been widely used in recent years in the development of vaccines. …”
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Establishment of a Southern catfish (Silurus meridionalis) spermatogonial stem cell line capable of sperm production in vitro by Jianeng Li, Changle Zhao, Lei Liu, Shuqing Zheng, Deshou Wang, Changwei Shao, Jing Wei

“…Transfection efficiency exceeding 50 % was achieved utilizing microporous membrane electroporation. …”
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