Heterologous Overexpression of Cytochrome P450BM3 from <i>Bacillus megaterium</i> and Its Role in Gossypol Reduction by Wenpeng Fan, Jingjing Cui, Tongxiang Xu, Shiheng Xu, Zulibina Ainiwaer, Qiyu Luo, Caidie Wang

“…Site-directed mutagenesis generated mutants (R162H, R162K, Q129H, Q129N) to explore structural determinants of catalytic efficiency. Both wild-type P450BM3 and mutants exhibited significant ability to reduce gossypol levels, with R162H and R162K showing 33.4% and 24.2% reduced catalytic efficiency compared with the wild-type enzyme, respectively. …”
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Scalable Hyperspectral Enhancement via Patch-Wise Sparse Residual Learning: Insights from Super-Resolved EnMAP Data by Parth Naik, Rupsa Chakraborty, Sam Thiele, Richard Gloaguen

“…The spectral and spatial characteristics of the scene encoded in the dictionary enable reconstruction through a first-order optimization algorithm to ensure an efficient sparse representation. The final spatially enhanced HSI is reconstructed by combining the learned features from low-resolution HSI and applying an MSI-regulated guided filter to enhance spatial fidelity while minimizing artifacts. …”
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Construction and demolition waste material library based on vision systems dataZenodo by Maria Teresa Calcagni, Giovanni Salerno, Gloria Cosoli, Giuseppe Pandarese, Gian Marco Revel

“…These methodologies were selected for their ability to provide complementary information on the chemical composition and physical properties of materials. …”
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Inactivation of Emerging Opportunistic Foodborne Pathogens <i>Cronobacter</i> spp. and <i>Arcobacter</i> spp. on Fresh Fruit and Vegetable Products: Effects of Emerging Chemical an... by Junior Bernardo Molina-Hernandez, Beatrice Cellini, Fatemeh Shanbeh Zadeh, Lucia Vannini, Pietro Rocculi, Silvia Tappi

“…This review provides the fruit and vegetable industry with a general overview of possible decontamination alternatives to develop optimal and efficient processes that ensure food safety.…”
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RGB and RGNIR image dataset for machine learning in plastic waste detectionZENODO by Owen Tamin, Ervin Gubin Moung, Jamal Ahmad Dargham, Samsul Ariffin Abdul Karim, Ashraf Osman Ibrahim, Nada Adam, Hadia Abdelgader Osman

“…Machine learning has emerged as a potential solution for plastic waste due to its ability to analyse and interpret large volumes of data using algorithms. …”
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Ensemble learning approach for prediction of early complications after radiotherapy for head and neck cancer using CT and MRI radiomic features by Benyamin Khajetash, Seied Rabi Mahdavi, Alireza Nikoofar, Lee Johnson, Meysam Tavakoli

“…Ensemble classifiers are more efficient than individual classifiers in prediction of early xerostomia.…”
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Multiple factors based adaptive laboratory evolution strategy enhances DHA production in Aurantiochytrium sp. PKU#Mn16 by rewiring key metabolic pathways by Xueyan Ding, Xingyu Zhu, Yuetong Zhao, Ningdong Xie, Guangyi Wang

“…Abstract Background Marine protists Aurantiochytrium are recognized as promising sources for commercial lipid production, particularly due to their ability to produce high-value natural compounds like docosahexaenoic acid (DHA). …”
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Attention-based multi-scale convolution and conformer for EEG-based depression detection by Ze Yan, Ze Yan, Ze Yan, Yumei Wan, Xin Pu, Xiaolin Han, Mingming Zhao, Haiyan Wu, Wentao Li, Xueying He, Yunshao Zheng

“…The BiGRU module improves the model’s ability to recognize depressive states by utilizing bidirectional modeling. …”
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Predicting cardiotoxicity in drug development: A deep learning approach by Kaifeng Liu, Huizi Cui, Xiangyu Yu, Wannan Li, Weiwei Han

“…Using computational methods, this study facilitates a more efficient drug development process, reduces costs, and improves the safety of new drug candidates, ultimately benefiting medical and public health.…”
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Improvement in Biological Performance of Poly(Lactic Acid)-Based Materials via Single-Point Surface Modification with Glycopolymer by Viktor Korzhikov-Vlakh, Ekaterina Sinitsyna, Kirill Arkhipov, Mariia Levit, Evgenia Korzhikova-Vlakh, Tatiana Tennikova

“…The developed single-point polymer grafting approach provided the efficient functionalization with a grafting density in the range of 5–23 nmol/cm². …”
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Investigating size and surface modification to optimise the delivery of nanodiamonds to brain glial cells by Manami Takahashi, Ayaka Takada, Chihiro Suzuki, Kiichi Kaminaga, Masaki Yoshioka, Mariko Handa, Jeff Kershaw, Hiroshi Abe, Takeshi Ohshima, Ryuji Igarashi, Hiroyuki Takuwa

“…HPG-modified NDs also exhibited high diffusivity, facilitating interactions with surrounding microglia and enhancing uptake efficiency. In contrast, COOH-modified NDs were more efficiently internalized by astrocytes than HPG-modified NDs. …”
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Metal Ruthenium Complexes Treat Spinal Cord Injury By Alleviating Oxidative Stress Through Interaction With Antioxidant 1 Copper Chaperone Protein by Juanjuan Li, Cheng Peng, Caiqiang Huang, Li Wan, Ke Wang, Ping Wu, Tianjun Chen, Guodong Sun, Rui Guo, Hongsheng Lin, Zhisheng Ji

“…Thus, this treatment strategy using ruthenium metal complexes can be a new therapeutic approach for the efficient treatment of SCI.…”
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Training‐Augmented Ionic Switch for Logic Signal Modulation by Rui Jia, Xiaozheng Duan, Kaige Wang, Fengqiang Sun, Teng Li, Zhu Chen, Le Wang, Gang Wang, Liang‐Wen Feng, Hengda Sun, Meifang Zhu

“…Abstract Efficient ionic conductivity switching is crucial for the progression of iontronics, where adaptability and dynamic control are desirable to the innovation of intelligent devices. …”
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Covalent Affibody‐Molecular Glue Drug Conjugate Nanoagent for Proximity‐Enabled Reactive Therapeutics by Wenhui Gao, Xiaoyuan Yang, Qingrong Li, Yingchun Liu, Wei Huang, Xuelin Xia, Deyue Yan

“…Abstract Sulfur‐fluoride exchange (SuFEx) reaction is an emerging class of click chemistry reaction. Owing to its efficient reactivity under physiological conditions, SuFEx reaction is used to construct covalent protein drugs. …”
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Effect and mechanisms of chelating agents on pore structure variation and permeability enhancement of low permeability coal seams by Shuya CHEN, Jihua CAI, Xianyu YANG, Fudong XIN, Lu ZHANG

“…These findings can provide valuable ideas for efficient exploration and development of low-permeability coalbed methane.…”
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Targeted Screening of <i>Lactiplantibacillus plantarum</i> Strains Isolated from Tomatoes and Its Application in Tomato Fermented Juice by Nuersiman Tuerhong, Liang Wang, Jie Cui, Dilireba Shataer, Huizhen Yan, Xiaoxiao Dong, Ziqi Gao, Minwei Zhang, Yanan Qin, Jing Lu

“…Antioxidant activity varied, with strain A24 showing the highest hydroxyl radical scavenging ability, while strains with high surface hydrophobicity had lower DPPH scavenging activity, indicating no direct correlation between these properties. …”
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Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range by Zehua Chen, Junyuan Xue, Ziying Wang, Jinyuan Sun, Yinglu Cui, Tong Zhu, Huaiyi Yang, Ming Li, Bian Wu

“…EnErCas12a demonstrates the ability to recognize GC‐rich PAMs and target five times more PAM sequences than the wild‐type ErCas12a. …”
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Innovative Mycotoxin Detoxifying Agents Decrease the Absorption Rate of Aflatoxin B1 and Counteract the Oxidative Stress in Broiler Chickens Exposed to Low Dietary Levels of the My... by Matteo Cuccato, Neenu Amminikutty, Veronica Spalenza, Vanessa Conte, Stefano Bagatella, Donato Greco, Vito D’Ascanio, Francesco Gai, Achille Schiavone, Giuseppina Avantaggiato, Carlo Nebbia, Flavia Girolami

“…The inclusion of mycotoxin detoxifying agents (MyDA) with binding properties in the diet is an efficient tool to reduce their absorption rate in the gastrointestinal tract. …”
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Utilizing Virtual Reality in the participatory urban policy-making process: A step toward facilitating effective citizen engagement by A. Shakibamanesh, M. Ghorbanian, S. Izadi, A. Riahi, P. Zeifodini

“…By providing immersive simulations, virtual Reality can improve transparency, enhance stakeholder collaboration, and facilitate informed decision-making in urban planning. The technology's ability to engage diverse demographic groups, particularly those reluctant to engage in traditional methods, shows promise for making urban policy discussions more interactive and understandable. …”
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Meloxicam mitigated methylglyoxal-induced glycative stress in rats by Talha Fayyaz, Ghulam Abbas, Hammad Ahmed, Najeeb Khatian, Shumaila Usman, Uzair Nisar, Noor Ain, Yamna Khurshid, Syed Ali

“…Drug repurposing is an efficient and cost-effective way of developing drugs. …”
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