Tumor-targeting nanomaterials based on metal-organic frameworks mediate tumor immunotherapy by promoting cuproptosis and pyroptosis in hepatocellular carcinoma cells by Xiaoyuan Yi, Huaying Xie, Kunzhao Huang, Jianzhang Luo, Wen Li, Qingyu Zeng, Feifei He, Wuxiang Shi, Duo Wang, Liyan Wang

“…In this study, copper-based metal-organic framework nanoparticles (referred to as FA-PZ@MOF NPs), which have the ability to simultaneously induce cuproptosis and pyroptosis in tumor cells, were designed to utilize the synergistic effects of cuproptosis and pyroptosis to trigger immunogenic cell death (ICD). …”
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A review of the search for AGB stars by Hai-Ling Lu, Hai-Ling Lu, Yin-Bi Li, A-Li Luo, A-Li Luo, A-Li Luo, Zhi-Qiang Zou, Zhi-Qiang Zou, Zhi-Qiang Zou, Xiao-Ming Kong, Zhen-Ping Yi, Hugh R. A. Jones, Jun-Chao Liang, Jun-Chao Liang, Shuo Li, Shuo Li

“…We also explore the possibility of using interpretable machine learning algorithms to discover new features and applying deep learning algorithms to enhance search efficiency. With the advancement of data processing technology and the widespread application of machine learning methods, future AGB star searches will be more accurate and efficient. …”
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NeuroScale: evolutional scale-based protein language models enable prediction of neuropeptides by Hongqi Zhang, Shanghua Liu, Wei Su, Xueqin Xie, Junwen Yu, Fuying Dao, Mi Yang, Hao Lyu, Hao Lin

“…By providing a scalable and efficient deep learning framework, NeuroScale paves the way for future research in neuropeptide function, disease mechanisms, and therapeutic applications.…”
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DenseGNN: universal and scalable deeper graph neural networks for high-performance property prediction in crystals and molecules by Hongwei Du, Jiamin Wang, Jian Hui, Lanting Zhang, Hong Wang

“…The LOPE strategy optimizes the embedding representation of atoms and allows our model to train efficiently with a minimal level of edge connections. …”
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Coupling research on employment centers and their service area with rail transit network-a case study of Shanghai, China by Wang Jun-Li, Hu Gang-Yu, Huang Jian-Zhong, Zhang Tian-Ran, Wang Jing-Xin

“…Compared to other centers, regional center has a strong distribution of sphere of influence of employment centers. 3) The number and accessibility of rail transit stations significantly influence the ability to gather large numbers of employees, supporting the radial expansion of employment centers. …”
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EPI-DynFusion: enhancer-promoter interaction prediction model based on sequence features and dynamic fusion mechanisms by Ao Zhang, Jianhua Jia, Mingwei Sun, Xin Wei

“…As a result, the development of efficient computational models has become essential. …”
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Single-Scene SAR Image Data Augmentation Based on SBR and GAN for Target Recognition by Shangchen Feng, Xikai Fu, Yanlin Feng, Xiaolei Lv

“…Hence, it is essential to integrate physics-based simulation techniques into GANs to enhance the generalization ability of the imaging parameters. In this paper, we present the SingleScene-SAR Simulator, an efficient framework for SAR image simulation that operates under limited real SAR data. …”
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Environmental impact assessment of organic Rankine cycle using waste heat from the aluminium industry by Monika Dokl, Gaja Strajnar, Annamaria Vujanović, Jan Puhar, Zdravko Kravanja, Lidija Čuček

“…These findings highlight the importance of the thermal input quality and availability in maximizing ORC performance. With the ability to prioritize electricity, heat, or both, the optimized ORC systems support flexible energy solutions tailored to specific applications and environmental conditions, offering a promising pathway for unburdening the environment through the efficient utilization of industrial waste heat.…”
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Furin-Triggered Peptide Self-Assembly Activates Coumarin Excimer Fluorescence for Precision Live-Cell Imaging by Peiyao Chen, Liling Meng, Yuting Wang, Xiaoya Yan, Meiqin Li, Yun Deng, Yao Sun

“…Monomer-to-excimer transition has become a valuable technique in fluorescence imaging because of its ability to enhance imaging contrast. However, from a practical perspective, the accuracy of excimer formation at target sites warrants further exploration. …”
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A deep learning approach to predict differentiation outcomes in hypothalamic-pituitary organoids by Tomoyoshi Asano, Hidetaka Suga, Hirohiko Niioka, Hiroshi Yukawa, Mayu Sakakibara, Shiori Taga, Mika Soen, Tsutomu Miwata, Hiroo Sasaki, Tomomi Seki, Saki Hasegawa, Sou Murakami, Masatoshi Abe, Yoshinori Yasuda, Takashi Miyata, Tomoko Kobayashi, Mariko Sugiyama, Takeshi Onoue, Daisuke Hagiwara, Shintaro Iwama, Yoshinobu Baba, Hiroshi Arima

“…Three-dimensional culture is inherently characterized by its ability to induce heterogeneous cell populations, making it difficult to maintain constant differentiation efficiency. …”
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Bridging verbal coordination and neural dynamics by Isaïh Schwab-Mohamed, Manuel R Mercier, Agnès Trebuchon, Benjamin Morillon, Leonardo Lancia, Daniele Schön

“…This synchronous speech task is efficient to highlight both the dorsal and ventral language pathways. …”
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An Hfq-dependent post-transcriptional mechanism fine tunes RecB expression in Escherichia coli by Irina Kalita, Ira Alexandra Iosub, Lorna McLaren, Louise Goossens, Sander Granneman, Meriem El Karoui

“…RecBCD is essential for accurate chromosome maintenance, but its over-expression can lead to reduced DNA repair ability. This apparent paradox suggests that RecBCD copy numbers may need to be tightly controlled within an optimal range. …”
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Enhancing grid connected wind energy conversion systems through fuzzy logic control optimization with PSO and GA techniques by Abdelhalim Borni, Noureddine Bessous, Layachi Zaghba, Abdelhak Bouchakour, Melkamu Sisay Agmas, Enas Ali, Sherif S. M. Ghoneim, Ayman Hoballah

“…The novelty of employing fuzzy logic control optimized with PSO and GA lies in its ability to address inherent challenges in wind energy systems, such as varying wind speeds and grid voltage fluctuations. …”
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D³-YOLOv10: Improved YOLOv10-Based Lightweight Tomato Detection Algorithm Under Facility Scenario by Ao Li, Chunrui Wang, Tongtong Ji, Qiyang Wang, Tianxue Zhang

“…Accurate and efficient tomato detection is one of the key techniques for intelligent automatic picking in the area of precision agriculture. …”
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Tri-Level Adaptive Robust Optimization for the Optimal Charging Coordination of EVs Considering Grid Impact by Jessica Alice A. Silva, Juan Camilo Lopez, Nataly Banol Arias, Lucas Zenichi Terada, Marcos J. Rider

“…The rapid integration of electric vehicles (EVs) into power grids introduces substantial operational challenges, particularly in managing the grid and ensuring efficient energy distribution. Addressing these issues, this paper presents a novel tri-level adaptive robust optimization model for EV charging coordination, explicitly considering active and reactive power control (RPC) and its impact on the distribution network. …”
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Call to action: recognize and prevent the effects of extreme heat on early childhood development and health by Vanitha Sampath, Devon Payne-Sturges, Natalie Slopen, Nathaniel Harnett, Nathaniel Harnett, Alison G. Lee, Kari Nadeau, Nat Kendall Taylor, Lindsey Burghardt, Lindsey Burghardt

“…Long-term impacts include lower cognitive function, reduced ability to concentrate, and adverse outcomes in mental and behavioral health. …”
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Classification of Vaginal Cleanliness Grades through Surface‐Enhanced Raman Spectral Analysis via The Deep‐Learning Variational Autoencoder–Long Short‐Term Memory Model by Jia‐Wei Tang, Xin‐Ru Wen, Hui‐Min Chen, Jie Chen, Kun‐Hui Hong, Quan Yuan, Muhammad Usman, Liang Wang

“…Among all algorithms, the VAE–LSTM algorithm demonstrates the best prediction ability and time efficiency. Additionally, blind test datasets yielded an overall accuracy of 85%. …”
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Identifying dominant quinones in digested sludge at trace levels using online supercritical fluid extraction–liquid chromatography by Farida Hanum, Mona F. A. Dawood, Yoichi Atsuta, Hiroyuki Daimon

“…Furthermore, the method efficiently identified the quinone species in a pure bacterial culture of Moorella sp. …”
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Comparative study of the effect of water stress on morphological, physiological and biochemical parameters of three Aloe species by Mourad Derouiche, Fadoua Chkird, Anass Alla, Hajar Hamdaoui, Sabir Ouahhoud, Redouane Benabess, Ibtissam Mzabri, Abdelbasset Berrichi, Youssouf Ali Younous, Pravin Badhe, Khalid S. Almaary, Noureddine Kouddane

“…These physiological and biochemical adaptations enable efficient water conservation.…”
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Triple Design Strategy for Quinoxaline-Based Hole Transport Materials in Flexible Perovskite Solar Cells by Yuanqiong Lin, Zeyuan Gao, Xiaoshang Zhong, Yinghua Lu, Song Tu, Xin Li

“…Molecular design strategies such as noncovalent conformational locks, self-assembly, and D-A molecular skeletons have been extensively used to devise efficient and stable hole transport materials. Nevertheless, most of the existing excellent examples involve only single or dual strategies, and triple strategies remain scarcely reported. …”
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