Co-expression of IL-15 and CCL21 strengthens CAR-NK cells to eliminate tumors in concert with T cells and equips them with PI3K/AKT/mTOR signal signature by Jie Zhou, Lu Tang, Yu Hu, Jun Deng, Yingying Li, Wei Xiong, Jianghua Wu, Jia Xu, Wenjing Luo, Heng Mei, Xindi Wang, Zhaozhao Chen, Chenggong Li, Zhongpei Huang, Zhuolin Wu, Yinqiang Zhang, Yun Kang, Qiaolin Liu

“…Cooperation with T cells promoted efficient tumor-cell elimination, alleviated mutual exhaustion phenotypes, and enhanced the expression of effector molecules/receptors. …”
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Explainable artificial intelligence visions on incident duration using eXtreme Gradient Boosting and SHapley Additive exPlanations by Khaled Hamad, Emran Alotaibi, Waleed Zeiada, Ghazi Al-Khateeb, Saleh Abu Dabous, Maher Omar, Bharadwaj R.K. Mantha, Mohamed G. Arab, Tarek Merabtene

“…Efficient management of traffic incidents is a focal point in traffic management, with direct implications for road safety, congestion, and the environment. …”
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Green and facile fabrication of high-performance antibacterial nanofiber materials with low cytotoxicity using eggshell membrane hydrolysate by Ling Wang, Junpeng Xiong, Fanghua Liang, Azeem Ullah, Sabeen Gohar, Gopiraman Mayakrishnan, Ji Ha Lee, Ick Soo Kim

“…Developing high-performance antibacterial materials through eco-friendly and efficient strategies is vital for combating infections and promoting global sustainability. …”
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Advancements in sorption-enhanced steam reforming for clean hydrogen production: A comprehensive review by Ahmad Salam Farooqi, Abdelwahab N. Allam, Muhammad Zubair Shahid, Anas Aqil, Kevin Fajri, Sunhwa Park, Omar Y. Abdelaziz, Mahmoud M. Abdelnaby, Mohammad M. Hossain, Mohamed A. Habib, Syed Muhammad Wajahat ul Hasnain, Ali Nabavi, Mingming Zhu, Vasilije Manovic, Medhat A. Nemitallah

“…This comprehensive review thoroughly explores the SE-SMR process, highlighting its ability to efficiently combine carbon capture with hydrogen generation. …”
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Comprehensive analysis of multi‐omics single‐cell data using the single‐cell analyst by Lu Pan, Bufu Tang, Xuan Zhang, Paolo Parini, Roman Tremmel, Joseph Loscalzo, Volker M. Lauschke, Bradley A. Maron, Paola Paci, Ingemar Ernberg, Nguan Soon Tan, Ákos Végvári, Zehuan Liao, Sundararaman Rengarajan, Roman Zubarev, Yuxuan Fan, Xu Zheng, Xinyue Jian, Ren Sheng, Zhenning Wang, Xuexin Li

“…Abstract The rapid advancement of multi‐omics single‐cell technologies has significantly enhanced our ability to investigate complex biological systems at unprecedented resolution. …”
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A panting behavior-driven assessment framework for summer ventilation quality optimization in layer houses by Zixuan Zhou, Lihua Li, Hao Xue, Yuchen Jia, Yao Yu, Zongkui Xie, Yuhan Gu

“…Significant physiological differences (p < 0.05) in chickens across VQ grades validated the model's discriminative ability. The method accurately identified latent ventilation anomalies and spatial dead zones in large-scale layer houses. …”
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An “EVs-in-ECM” mimicking system orchestrates transcription and translation of RUNX1 for in-situ cartilage regeneration by Qi Cheng, Qianping Guo, Xiaoyu Zhang, Yuanchen Zhu, Chengyuan Liu, Huan Wang, Caihong Zhu, Li Ni, Bin Li, Huilin Yang

“…The self-repair ability of articular cartilage is limited, which is one of the most difficult diseases to treat clinically. …”
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Dual drug-loaded tumor-targeted polymeric nanoparticles for enhancing therapeutic response in pancreatic ductal adenocarcinoma by Naga Malleswara Rao Nakka, Hari Krishnareddy Rachamala, Ramcharan Singh Angom, Nagamalleswara Rao Indla, Shamit Kumar Dutta, Enfeng Wang, Santanu Bhattacharya, Annadanam V. Sesha Sainath, Hani Babiker, Krishnendu Pal, Debabrata Mukhopadhyay

“…These nanoformulations demonstrated excellent stability under in vitro physiological conditions and led to an efficient release of the drugs in the presence of reduced glutathione (GSH). …”
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3-O-trans-p-coumaroyl esterification enhances the anti-inflammatory effects of tormentic acid by targeting NF-κB signaling by Mara Heckmann, Lea Karlsberger, Bernhard Blank-Landeshammer, Gerald Klanert, Nadiia Sadova, Verena Stadlbauer, Georg Sandner, Theresa Gramatte, Simone Kasis, Julian Weghuber

“…This study investigates how hydroxycinnamoyl esterification influences the biological activity of pentacyclic triterpenes by comparing TA and trans-TACE in cellular and in vivo stress models.We assessed their ability to mitigate oxidative stress by evaluating the inhibition of ROS and NO molecules. …”
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Self-organizing expert communities in educational projects by Gennadiy P. Vinogradov, Vladimir N. Kuznetsov

“…To carry out production activities, a specialist uses a complex of abilities, knowledge and skills that should be considered as models of his production and technological activities. …”
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Dynamic mapping of dissolved oxygen in freshwater aquaculture ponds using UAV multispectral imagery by Xingyu Liu, Yancang Wang, Xiaohe Gu, Mengjie Li, Wenxu Lv, Xuqing Li, Ruiyin Tang, Guangxin Chen, Baoyuan Zhang, Shuaifei Liu, Fajian Zong, Yongkun Ji, Xiaolong Yu, Tianen Chen

“…UAV multispectral imaging technology combined with this method can efficiently and accurately capture the spatial and temporal distribution of DO in freshwater aquaculture pond, supporting aquaculture management.…”
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Green Synthesized Composite AB-Polybenzimidazole/TiO₂ Membranes with Photocatalytic and Antibacterial Activity by Hristo Penchev, Katerina Zaharieva, Silvia Dimova, Ivelina Tsacheva, Rumyana Eneva, Stephan Engibarov, Irina Lazarkevich, Tsvetelina Paunova-Krasteva, Maria Shipochka, Ralitsa Mladenova, Ognian Dimitrov, Daniela Stoyanova, Irina Stambolova

“…Modified Eaton’s reagent (methansulfonic acid/P₂O₅) was used as both reaction media for microwave-assisted synthesis of AB-PBI and as an efficient dispersant of partially agglomerated titanium dioxide powders. …”
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Fpa (YlaN) is an iron(II) binding protein that functions to relieve Fur-mediated repression of gene expression in Staphylococcus aureus by Jeffrey M. Boyd, Kylie Ryan Kaler, Karla Esquilín-Lebrón, Ashley Pall, Courtney J. Campbell, Mary E. Foley, Gustavo Rios-Delgado, Emilee M. Mustor, Timothy G. Stephens, Hannah Bovermann, Todd M. Greco, Ileana M. Cristea, Valerie J. Carabetta, William N. Beavers, Debashish Bhattacharya, Eric P. Skaar, Lindsey N. Shaw, Timothy L. Stemmler

“…Questions remain about how cells efficiently balance Fe uptake and usage to prevent overload. …”
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Improving the Theranostic Potential of Magnetic Nanoparticles by Coating with Natural Rubber Latex for Ultrasound, Photoacoustic Imaging, and Magnetic Hyperthermia: An In Vitro Stu... by Thiago T. Vicente, Saeideh Arsalani, Mateus S. Quiel, Guilherme S. P. Fernandes, Keteryne R. da Silva, Sandra Y. Fukada, Alexandre J. Gualdi, Éder J. Guidelli, Oswaldo Baffa, Antônio A. O. Carneiro, Ana Paula Ramos, Theo Z. Pavan

“…Background/Objectives: Magnetic nanoparticles (MNPs) have gained attention in theranostics for their ability to combine diagnostic imaging and therapeutic capabilities in a single platform, enhancing targeted treatment and monitoring. …”
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Synergistic effects of fluorination on CO2 capture and activation in 1,2,3-triazolium ionic liquids by Gustavo Chacón-Rosales, Cristián Valdebenito, Karina Muñoz-Becerra, Carlos Cruz, Cesar Morales-Verdejo, Kerry Wrighton-Araneda, Pedro Aguirre, Gabriel Abarca

“…Ionic liquids (ILs) have emerged as highly promising candidates for CO₂ capture due to their tuneable physicochemical properties, negligible vapor pressure, and ability to be tailored for specific molecular interactions with CO₂. …”
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A novel deep learning-based spider wasp optimization approach for enhancing brain tumor detection and physical therapy prediction by Suleiman Daoud, Ahmad Nasayreh, Khalid M.O. Nahar, Wlla k. Abedalaziz, Salem M. Alayasreh, Hasan Gharaibeh, Ayah Bashkami, Amer Jaradat, Sultan Jarrar, Hammam Al-Hawamdeh, Absalom E. Ezugwu, Raed Abu Zitar, Aseel Smerat, Vaclav Snasel, Laith Abualigah

“…The results clearly demonstrate the ability of the proposed SWO+KNN model to accurately classify brain tumors.…”
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Subjective cognitive decline predicts longitudinal neuropsychological test performance in an unsupervised online setting in the Brain Health Registry by Jae Myeong Kang, Manchumad Manjavong, Chengshi Jin, Adam Diaz, Miriam T. Ashford, Joseph Eichenbaum, Emily Thorp, Elizabeth Wragg, Kenton H. Zavitz, Francesca Cormack, Anna Aaronson, R. Scott Mackin, Rachana Tank, Bernard Landavazo, Erika Cavallone, Diana Truran, Sarah Tomaszewski Farias, Michael W. Weiner, Rachel L. Nosheny

“…Abstract Backgrounds Digital, online assessments are efficient means to detect early cognitive decline, but few studies have investigated the relationship between remotely collected subjective cognitive change and cognitive decline. …”
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Screening for Drought Tolerance Within a Common Bean (<i>Phaseolus vulgaris</i> L.) Landrace Accessions Core Collection from the Lazio Region of Italy by Enrica Alicandri, Ester Badiani, Anna Rita Paolacci, Emilio Lo Presti, Roberta Caridi, Roberto Rea, Francesco Pati, Maurizio Badiani, Mario Ciaffi, Agostino Sorgonà

“…By taking into account the concept of “yield stability”, i.e., the ability to maintain comparatively high yields even under conditions of water scarcity, certain common bean landraces were found to be the most promising, in terms of drought tolerance. …”
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Modeling maize growth and nitrogen dynamics using CERES-Maize (DSSAT) under diverse nitrogen management options in a conservation agriculture-based maize-wheat system by Kamlesh Kumar, C. M. Parihar, H. S. Nayak, D. R. Sena, Samarth Godara, Rajkumar Dhakar, Kiranmoy Patra, Ayan Sarkar, Sneha Bharadwaj, Prakash Chand Ghasal, A. L.Meena, K. Srikanth Reddy, T. K. Das, S. L. Jat, D. K. Sharma, Y. S. Saharawat, Upendra Singh, M. L. Jat, M. K. Gathala

“…The study also demonstrated the model's ability to accurately capture soil nitrate–N levels (RMSE 12.63 kg/ha and nRMSE 12.84%). …”
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Impacts of Ecological Restoration Projects on Ecosystem Carbon Storage of Tongluo Mountain Mining Area, Chongqing, in Southwest China by Lei Ma, Manyi Li, Chen Wang, Hongtao Si, Mingze Xu, Dongxue Zhu, Cheng Li, Chao Jiang, Peng Xu, Yuhe Hu

“…Surface mining activities cause severe disruption to ecosystems, resulting in the substantial destruction of surface vegetation, the loss of soil organic carbon stocks, and a decrease in the ecosystem’s ability to sequester carbon. The ecological restoration of mining areas has been found to significantly enhance the carbon storage capacity of ecosystems. …”
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