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7221
Optimization of lentiviral delivery of barcoded anti-CD20 chimeric antigen receptors into rhesus macaque and human natural killer cells
Published 2025-06-01“…We found that P407 significantly improved transduction efficiency, achieving up to 60% in expanded RM NK cells, without compromising cell viability or functionality. …”
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7222
Feasibility Assessment of an Optically Powered Digital Retinal Prosthesis Architecture for Retinal Ganglion Cell Stimulation
Published 2025-01-01“…To overcome the limitations imposed by cables, a retinal implant architecture in which near-infrared illumination carries both power and data through the pupil to a digital stimulation controller is presented. A high efficiency multi-junction photovoltaic cell transduces the optical power to a CMOS stimulator capable of delivering flexible interleaved sequential stimulation through a diamond microelectrode array. …”
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7223
Complementary strengths of water footprint and life cycle assessments in analyzing global freshwater appropriation and its local impacts – Recommendations from an Interdisciplinary...
Published 2025-05-01“…Our analysis revealed that WFA’s strength lies in its ability to measure freshwater appropriation, water-use efficiency, water scarcity and total pollution levels. …”
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7224
A Review of Enhancement of Thermal Performance of Flat Plate Solar Collectors through Nanofluid Implementation
Published 2023-09-01“…Collectively, these studies demonstrate the impressive heat transfer abilities of nanofluids. To optimize the efficiency of flat plate solar collectors, a comprehensive approach integrating theory and experimentation is essential. …”
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7225
Comprehensive analysis of multi‐omics single‐cell data using the single‐cell analyst
Published 2025-06-01“…Abstract The rapid advancement of multi‐omics single‐cell technologies has significantly enhanced our ability to investigate complex biological systems at unprecedented resolution. …”
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7226
A panting behavior-driven assessment framework for summer ventilation quality optimization in layer houses
Published 2025-08-01“…The YOLOv10-BCE panting behavior detection model was developed by embedding the BiFormer module into the backbone network to enhance multi-dimensional feature extraction, compressing neck structure parameters using the C3Ghost module, and integrating Efficient Intersection over Union (EIOU) loss to improve detection accuracy and convergence speed. …”
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7227
Application of mesenchymal stem cells in liver fibrosis and regeneration
Published 2024-12-01“…However, challenges still exist in the clinical application of MSCs, including low differentiation efficiency and limited sources. This review provides a reference for MSC application in liver disease treatment. …”
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7228
Rapid adaptation to human protein kinase R by a unique genomic rearrangement in rhesus cytomegalovirus.
Published 2021-01-01“…Cytomegaloviruses (CMVs) are generally unable to cross species barriers, in part because prolonged coevolution with one host species limits their ability to evade restriction factors in other species. …”
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7229
Petiveria alliacea and Caesalpinia spinosa extracts reduce the generation of cancer-associated fibroblasts in a 3D platform representative of the tumor microenvironment
Published 2025-07-01“…Therefore, developing therapies that target CAFs constitute valuable therapeutic alternatives. However, efficiently modeling the generation of CAFs in the tumor microenvironment is challenging. …”
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7230
Innovative approaches in bioremediation: the role of halophilic microorganisms in mitigating hydrocarbons, toxic metals, and microplastics in hypersaline environments
Published 2025-08-01“…Techniques like gene editing and recombinant DNA have facilitated the precise modification of halophiles, enabling them to efficiently target and degrade toxic compounds and significantly improve their bioremediation potential. …”
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7231
An “EVs-in-ECM” mimicking system orchestrates transcription and translation of RUNX1 for in-situ cartilage regeneration
Published 2025-04-01“…The self-repair ability of articular cartilage is limited, which is one of the most difficult diseases to treat clinically. …”
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7232
Dual drug-loaded tumor-targeted polymeric nanoparticles for enhancing therapeutic response in pancreatic ductal adenocarcinoma
Published 2024-10-01“…These nanoformulations demonstrated excellent stability under in vitro physiological conditions and led to an efficient release of the drugs in the presence of reduced glutathione (GSH). …”
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7233
Utility of type 1 diabetes genetic risk score in a non-European population: insights from an Iranian cohort
Published 2025-06-01“…Abstract Background The present study aimed to investigate the efficiency of the type 1 diabetes genetic risk score (T1D GRS) in distinguishing between patients with type 1 and type 2 diabetes in Iran, an underrepresented population in genomic research. …”
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7234
Bergamot (<i>Citrus bergamia</i>): A Potential New Nutraceutical Against Cellular and Physiological Alterations Induced by Emerging Contaminants in Sentinel Organisms
Published 2025-04-01“…The analyses included cell viability of haemocytes and DG cells (trypan blue exclusion assay and the neutral red retention test); the ability of DG cells to regulate their volume (RVD); haemocyte phagocytic activity; expression of genes involved in antioxidant response (<i>Cu/ZnSOD, MnSOD, Hsp70</i>, and <i>CYP4Y</i>) on gills and DG; the energy efficiency of the organism through byssus production; and the measurement of key macromolecules, including total lipid and fatty acid content, total protein, tocopherols and carotenoids, which play a key role in maintaining physiological and metabolic functions in the organism. …”
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7235
Advances and applications of empirical mode decomposition and its variants in hydrology: A review
Published 2025-02-01“…Empirical Mode Decomposition (EMD) has garnered increasing attention due to its ability to analyze non-linear and non-stationary data. …”
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7236
Adipose-Derived Stem Cells from Fat Tissue of Breast Cancer Microenvironment Present Altered Adipogenic Differentiation Capabilities
Published 2019-01-01“…To investigate this aspect more in depth, we evaluated the effect of selective PPARγ activation and nutritional supplementation on the differentiation efficiency of BC ADSCs, noting that it was only with a strong differentiation stimuli that the process took place. …”
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7237
Development and application of a curcumin-cinnamon essential oil nanoemulsion agent against mycobacteria
Published 2025-06-01“…The nanoemulsion demonstrated high encapsulation efficiency (90.2%) and stability, with a stability coefficient of 0.984. …”
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7238
Effects of dietary sodium alginate and Lactobacillus reuteri on the growth, antioxidant capacity and intestinal health of largemouth bass (Micropterus salmoides)
Published 2025-07-01“…Functional polysaccharides and probiotics are recognized for their ability to increase the growth and health of fish, but research on the combined impacts of these two compounds on aquatic organisms is limited. …”
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7239
Alumina-supported cobalt, nickel, and copper single-atom catalysts for CO to CO2 conversion; a comparative DFT study
Published 2025-05-01“…Moreover, regarding the resulting data of DFT calculations and method along with the basis set M06-2×/SVP, it was identified that the single-atom catalyst, nickel, has the most efficiency in the oxidation reaction from CO to CO2. …”
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7240
Green Synthesized Composite AB-Polybenzimidazole/TiO<sub>2</sub> Membranes with Photocatalytic and Antibacterial Activity
Published 2024-12-01“…Modified Eaton’s reagent (methansulfonic acid/P<sub>2</sub>O<sub>5</sub>) was used as both reaction media for microwave-assisted synthesis of AB-PBI and as an efficient dispersant of partially agglomerated titanium dioxide powders. …”
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