Poly(ionic liquid) functionalization: A general strategy for strong, tough, ionic conductive, and multifunctional polysaccharide hydrogels toward sensors by Xue Yao, Sufeng Zhang, Ning Wei, Liwei Qian, Hao Ding, Jingtao Liu, Wenqi Song, Sergiu Coseri

“…Ingeniously, due to the inherent conductivity, design flexibility, and functional compatibility of the PILs, the hydrogels exhibit high conductivity (6.54 ± 0.17 mS cm−1), self‐healing ability (94.5% ± 2.0% efficiency), antibacterial properties, freezing resistance, water retention, and recyclability. …”
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Pathway activation model for personalized prediction of drug synergy by Quang Thinh Trac, Yue Huang, Tom Erkers, Päivi Östling, Anna Bohlin, Albin Osterroos, Mattias Vesterlund, Rozbeh Jafari, Ioannis Siavelis, Helena Backvall, Santeri Kiviluoto, Lukas Orre, Mattias Rantalainen, Janne Lehtiö, Soren Lehmann, Olli Kallioniemi, Yudi Pawitan, Trung Nghia Vu

“…We trained and validated DIPx in the AstraZeneca-Sanger (AZS) DREAM Challenge human cell-line dataset using two separate test sets: Test Set 1 comprised the combinations already present in the training set, while Test Set 2 contained combinations absent from the training set, thus indicating the model’s ability to handle novel combinations. The Spearman’s correlation coefficients between predicted and observed drug synergy were 0.50 (95% CI: 0.47–0.53) in Test Set 1 and 0.26 (95% CI: 0.22–0.30) in Test Set 2, compared to 0.38 (95% CI: 0.34–0.42) and 0.18 (95% CI: 0.16–0.20), respectively, for the best performing method in the Challenge. …”
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Co-culturing Bifidobacterium animalis ssp. lactis with Lactobacillus helveticus accelerates its growth and fermentation in milk through metabolic interactions by Zhi Zhong, Fei Sun, Sheng Xu, Jingda Lu, Rui Yang, Lai-Yu Kwok, Yongfu Chen

“…Our results demonstrated that co-culturing the M8 and H9 strains accelerated growth and fermentation efficiency. This enhancement effect is likely attributed to the strong proteolytic ability of the H9 strain, which hydrolyzes casein to produce small molecular peptides, alanine, tyrosine, and other growth-promoting factors. …”
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Development of a one-step multiplex RT-qPCR method for rapid detection of bovine diarrhea viruses by Dequan Yang, Li Ma, Zhongping Yang, Xianchao Yang, Jian Wang, Houbin Ju, Chunguang Lu, Yonggang Weng, Heping Zhao, Haixiao Shen, Xin Li, Feifei Ge, Xiaoxu Wang, Xiujuan Wu, Meng Xiang, Guidan Feng, Congsheng Tang, Shixin Huang, Hongjin Zhao

“…Furthermore, the assay exhibited excellent reproducibility, with coefficients of variation below 1.5%, a strong linear correlation (R2 > 0.996), and an amplification efficiency between 90% and 110%. …”
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A novel bacterium-like particles platform displaying antigens by new anchoring proteins induces efficacious immune responses by Lingdi Niu, Lingdi Niu, Mingchun Gao, Hongkun Ren, Xinqi De, Zhigang Jiang, Xinyao Zhou, Runhang Liu, Hai Li, Haoyuan Duan, Chuankun Zhang, Fang Wang, Junwei Ge

“…Bacterium-like particles (BLP) are the peptidoglycan skeleton particles of lactic acid bacteria, which have high safety, mucosal delivery efficiency, and adjuvant effect. It has been widely used in recent years in the development of vaccines. …”
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Establishment of a Southern catfish (Silurus meridionalis) spermatogonial stem cell line capable of sperm production in vitro by Jianeng Li, Changle Zhao, Lei Liu, Shuqing Zheng, Deshou Wang, Changwei Shao, Jing Wei

“…Transfection efficiency exceeding 50 % was achieved utilizing microporous membrane electroporation. …”
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Changes in the soil and rhizosphere microbiomes associated with bacterial wilt decline in the tomato monoculture field by Junwei Peng, Jinfeng Hou, Hong Liu, Dmitri V. Mavrodi, Olga V. Mavrodi, Feifei Sun, Minchong Shen, Xia Wang, Keke Dang, Min Yan, Hui Liang, Yuanhua Dong, Jiangang Li

“…Monoculture farming streamlines field equipment use and increases the efficiency of planting and harvesting, but at the same time, exacerbates the severity of soilborne diseases. …”
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Identification of a transcription factor AoMsn2 of the Hog1 signaling pathway contributes to fungal growth, development and pathogenicity in Arthrobotrys oligospora by Qianqian Liu, Kexin Jiang, Shipeng Duan, Na Zhao, Yanmei Shen, Lirong Zhu, Ke-Qin Zhang, Jinkui Yang

“…Introduction: Arthrobotrys oligospora has been utilized as a model strain to study the interaction between fungi and nematodes owing to its ability to capture nematodes by developing specialized traps. …”
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Differential Replication and Oncolytic Effects of Zika Virus in Aggressive CNS Tumor Cells: Insights from Organoid and Tumoroid Models by Rodolfo Sanches Ferreira, Elisa Helena Farias Jandrey, Isabela Granha, Alice Kei Endo, Raiane Oliveira Ferreira, Bruno Henrique Silva Araujo, Mayana Zatz, Oswaldo Keith Okamoto

“…Recent findings on the Zika virus’ (ZIKV) ability to infect and kill CNS neoplastic cells draw attention to the virus’ oncolytic potential. …”
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Biochar derived from citronella and oregano waste residues for removal of organic dyes and soil amendment by Marwa Rammal, Ghenwa Kataya, Adnan Badran, Lara Yazbeck, Chaden Haidar, Khodor Haidar Hassan, Akram Hijazi, Walid Meouche, Mikhael Bechelany, Mohammad H. El-Dakdouki

“…The exponential growth and prominence of the essential oil industry was associated with the generation of large amounts of plant residues which, if not managed properly, present an environmental threat due to their ability to contaminate soil and water systems. This study focuses on the valorization of residues generated from oregano and citronella plants following essential oil extraction. …”
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Enhanced myofibroblast differentiation of eMSCs in intrauterine adhesions by Jun Song, Meiqi Li, Yuan Tao, Yumeng Li, Canrong Mai, Jingting Zhang, Lan Yao, Shaoquan Shi, Jianyong Xu

“…The isolated eMSCs from IUA and controls show similar functions from the perspectives of cell morphology, proliferation, colony formation, exosome secretion, positive ratio of eMSC markers and conventional MSC markers, tri-differentiation efficiency, the ability of suppressing lymphocyte proliferation, cell aging, and promoting vascular tube formation. …”
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Synthesis of Ethylphosphonate Curcumin Mimics: Substituents Allow Switching Between Cytotoxic and Cytoprotective Activities by Valeria Romanucci, Rita Pagano, Solveigh C. Koeberle, Andreas Koeberle, Minh Bui Hoang, Sonia Di Gaetano, Domenica Capasso, Michele Francesco Maria Sciacca, Valeria Lanza, Carmelo Tempra, Fabio Lolicato, Armando Zarrelli, Danilo Milardi, Giovanni Di Fabio

“…Curcumin is recognized for its diverse biological activities, including the ability to induce apoptosis and ferroptosis. Therefore, it represents a promising candidate for the development of new compounds with neuroprotective and anticancer properties. …”
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Deep dive into hydrologic simulations at global scale: harnessing the power of deep learning and physics-informed differentiable models (<i>δ</i>HBV-globe1.0-hydroDL) by D. Feng, D. Feng, D. Feng, H. Beck, J. de Bruijn, J. de Bruijn, R. K. Sahu, Y. Satoh, Y. Wada, J. Liu, M. Pan, K. Lawson, C. Shen

“…Moreover, regionalized differentiable models demonstrated stronger spatial generalization ability (median KGE 0.64) than a traditional parameter regionalization approach (median KGE 0.46) and even LSTM for ungauged region tests across continents. …”
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Climate-smart agronomic practices and their appraisal among smallholder sorghum farmers in eastern Democratic Republic of Congo wetlands by Géant B. Chuma, Latifah Kisombola, Jean M. Mondo, Boaz Muliri, Jackson-Gilbert M. Majaliwa, Charles Kahindo, Katcho Karume

“…This study specifically aims at identifying CSA practices in use and factors driving their adoption among sorghum farmers and assessing their efficiency in improving sorghum yield under smallholder farming in South-Kivu. …”
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Effects of Na₂SeO₃ and Na₂SiO₃ on Cd uptake and accumulation in two different rice (Oryza Sativa L.) cultivars at jointing stage by DAI Zou, YU Huaqing, GUO Changchun, MA Jun, LI Na, YANG Zhiyuan, XU Hui, SUN Yongjian

“…Exogenous Na₂SeO₃ or Na₂SiO₃ also decreased the Cd content in the root and shoot of the two rice cultivars, and the Cd translocation coefficient from root to shoot decreased as well. Compared with the control, exogenous Na₂SeO₃ or Na₂SiO₃ also decreased the total Cd accumulation significantly, but their effects on the percentage distribution in different parts of rice were quite different. …”
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Early Development of Larvae and Juvenile of Largemouth Bass (Micropterus salmoides) and Selective Experiment on Different Feed Ingredient by Yuwan LI, Haohui LIANG, Yao QIN, Huijie LU, Minwei HUANG, Yanping MA, Guoxia WANG

“…There was no significant difference in the coefficient of fatness among the groups.【Conclusion】Largemouth bass is divided into three stages: the newly hatched larvae stage (0-4 dah), larval stage (5-15 dah), and juvenile stage (16- 26 dah). …”
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Design of a Wearable Exoskeleton Piano Practice Aid Based on Multi-Domain Mapping and Top-Down Process Model by Qiujian Xu, Meihui Li, Guoqiang Chen, Xiubo Ren, Dan Yang, Junrui Li, Xinran Yuan, Siqi Liu, Miaomiao Yang, Mufan Chen, Bo Wang, Peng Zhang, Huiguo Ma

“…This study designs and develops a wearable exoskeleton piano assistance system for individuals recovering from neurological injuries, aiming to help users regain the ability to perform complex tasks such as playing the piano. …”
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Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms by Esther Natalie Oliva, Shien Guo, Jennifer Lord-Bessen, Aylin Yucel, Roberto Latagliata, Massimo Breccia, Giuseppe A. Palumbo, Grazia Sanpaolo, Marta Riva, Valeria Santini, Uwe Platzbecker, Guillermo Garcia-Manero, Pierre Fenaux, Christopher G. Pelligra

“…The QOL-E domains/summary scores, except for QOL-SEX, had an adequate ability to detect change from baseline to Week 24. …”
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A human monoclonal antibody isolated from Japanese encephalitis virus vaccine-vaccinated volunteer neutralizing various flaviviruses by Dong Chen, Dong Chen, Dong Chen, Jiayi Zhang, Jiayi Zhang, Jiayi Zhang, Yusha Liu, Jiayang Zhu, Jie Chen, Hongxia Ni, Jinsheng Wen

“…We expressed mAb LZY3412 and evaluated its ability to bind to E proteins of dengue virus, JEV and ZIKV, neutralize JEV and ZIKV infections in vitro, protect mice against lethal JEV or ZIKV attack. …”
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Viral characterization of the reassortants between canine influenza H3N2 and human pandemic (2009) H1N1 and avian H9N2 viruses in canine ex vivo tracheal explants by Tonia T. Kam, Christine H. T. Bui, Hin-Wo Yeung, Peter C. H. Wong, Alex W. H. Chin, John M. Nicholls, Malik Peiris, Kenrie P. Y. Hui, Leo L. M. Poon, Michael C. W. Chan

“…Selected reassortants had enhanced replication efficiency and able to induce more proinflammatory cytokines than the parental strains, suggesting that these reassortants have a considerable zoonotic risk. …”
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