Treatment options applied to the preclinical studies using animal models for Chagas Disease: a systematic review and meta-analysis [version 3; peer review: 2 approved] by Haruna Luz Barazorda-Ccahuana, Mayron Antonio Candia-Puma, Miguel Angel Chavez-Fumagalli, Luis Daniel Goyzueta-Mamani, Rodolfo Cordeiro Cordeiro Giunchetti, Ricardo Andrez Machado-de-Ávila, Alexsandro Sobreira Galdino, Brychs Milagros Roque-Pumahuanca, Eduardo Antonio Ferraz Coelho, Laura Yesenia Machaca-Luque

“…Methods In this context, we conducted a systematic review and meta-analysis of preclinical studies employing animal models to verify the progress in CD treatment. …”
Get full text

Novel shortcut strategies in copositivity detection: Decomposition for quicker positive certificates by Johannes Zischg, Immanuel Bomze

“…Nevertheless, it plays a crucial role in tight bounds for conic approaches of several hard optimization problems. …”
Get full text

A Focus on the Role of Dietary Treatment in the Prevention of Retinal Dysfunction in Patients with Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency: A Systematic Review by Evelina Maines, Giorgia Gugelmo, Nicola Vitturi, Alice Dianin, Laura Rubert, Giovanni Piccoli, Massimo Soffiati, Vittoria Cauvin, Roberto Franceschi

“…<b>Background</b>: Long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) is an inborn error affecting fatty acid β-oxidation (FAO). …”
Get full text

Optimizing Energy Forecasting Using ANN and RF Models for HVAC and Heating Predictions by Khaled M. Salem, Javier M. Rey-Hernández, A. O. Elgharib, Francisco J. Rey-Martínez

Get full text

Optimizing Injection Molding for Propellers with Soft Computing, Fuzzy Evaluation, and Taguchi Method by M. Hedayati-Dezfooli, Mehdi Moayyedian, Ali Dinc, Mostafa Abdrabboh, Ahmed Saber, A. M. Amer

“…This research explores multi-objective optimization in injection molding with a focus on identifying the optimal configuration for the moldability index in aviation propeller manufacturing. …”
Get full text

Systematic Review on Automation of Central Tire Inflation System Based on Terrain Conditions by Carl Luis C. Ledesma, Charlothe John I. Tablizo, Marites B. Tabanao, Emmanuel A. Salcedo, Emmy Grace T. Requillo, John Paul T. Cruz

“…The current central tire inflation system (CTIS) alleviates this issue by adjusting the tire pressure to a predetermined reference level. However, the existing CTIS only adjusts the pressure based on load conditions through manual input for terrain types and lacks advanced intelligence for optimal automation. …”
Get full text

The Potential of Probiotics in Reducing Ventilator-Associated Pneumonia: A Literature-Based Analysis by Tao-An Chen, Ya-Ting Chuang, Szu-Chi Pai, Jin-Fu Zheng

“…While some randomized controlled trials (RCTs) suggest that specific strains, such as <i>Lactobacillus rhamnosus</i> GG and <i>Bifidobacterium breve</i>, may reduce VAP incidence, larger trials have not confirmed significant benefits. Systematic reviews and meta-analyses indicate a potential 28–38% relative risk reduction in VAP, but evidence quality remains low due to methodological limitations and study heterogeneity. …”
Get full text

Systematic review of the impact of ginger extract and alpinetin on pregnancy outcomes in animal models by Jonquile T. Williams, Kendra A. Tiani, Margaret J. Foster, Amanda J. MacFarlane, Regan L. Bailey, Patrick J. Stover, Martha S. Field

“…Methods A systematic protocol was registered with the Open Science Framework (OSF) ( https://doi.org/10.17605/OSF.IO/ADU68 ). …”
Get full text

A comprehensive review of patternless rapid sand casting using additive manufacturing process by bibliometrix R-tool by Yogesh Patil, K. P. Karunakaran, Milind Akarte, Gopal Gote, Yash Gopal Mittal, Avinash Kumar Mehta, Ashik Kumar Patel

“…Thus, literature and commercial AM systems are investigated to determine the causes. This study comprises a Systematic Literature Review (SLR) and Bibliometrix using the Biblioshiny web application for patternless sand mold and core production using RSC. …”
Get full text

Usability and optimization of online apps in user’s context by M. Waseem Iqbal, Khlood Shinan, Shahid Rafique Shahid Rafique, Abdullah Alourani, M. Usman Ashraf, Nor Zairah Ab Rahim

“…The OptiFlow framework introduces a novel approach for enhancing usability evaluation and optimization known as OptiFlow. …”
Get full text

Benchmarking the optimization of optical machines with the planted solutions by Nikita Stroev, Natalia G. Berloff, Nir Davidson

“…Additionally, the generated problems reveal properties such as the easy-hard-easy complexity transition and complex solution cluster structures. This method offers a promising platform for analyzing and understanding the behavior of physical hardware and its simulations, contributing to future advancements in optimization technologies.…”
Get full text

Optimized layout and excavation sequence of deep chambers by Shenghua YIN, Yongyuan KOU, Yun ZHOU, Zepeng YAN, Dexin ZENG

“…The results showed that the optimal cross-sectional shape for large-section chambers was a straight-walled circular arch section, which effectively reduced the stress concentration in the surrounding rock and enhanced the overall stability. …”
Get full text

Metaheuristics in automated machine learning: Strategies for optimization by Francesco Zito, El-Ghazali Talbi, Claudia Cavallaro, Vincenzo Cutello, Mario Pavone

“…This work aims to fill this gap by systematically evaluating the performance of metaheuristic algorithms in optimizing hyperparameters and discussing advanced techniques such as parallel computing to adapt metaheuristic algorithms for use in hyperparameter optimization with high-dimensional hyperparameter search space.…”
Get full text

Optimizing Spectral Utilization in Healthcare Internet of Things by Adeel Iqbal, Ali Nauman, Yazdan Ahmad Qadri, Sung Won Kim

“…Any delay or information loss can result in serious consequences, making spectrum availability a crucial bottleneck. This study systematically identifies challenges in optimizing spectrum utilization in healthcare IoT (H-IoT) networks, focusing on issues such as dynamic spectrum allocation, interference management, and prioritization of critical medical devices. …”
Get full text

Local recurrence of phyllodes tumors after surgery with wide compared to narrow margins: study protocol for a systematic review and meta-analysis by Carl Sars, Jan Frisell, Paul W. Dickman, Helena Sackey, Ebba K. Lindqvist

“…Discussion This systematic review will provide a synthesis of current evidence on the optimal surgical margins of phyllodes tumors and its effect on local recurrence rates. …”
Get full text

Wood Waste Valorization and Classification Approaches: A systematic review [version 2; peer review: 2 approved, 1 approved with reservations] by Lucyna Lekawska-Andrinopoulou, AKRIVI KORBA, Kostas Chatziioannou, Angelos Amditis, Georgios Tsimiklis

“…Furthermore, the review identifies existing gaps in research and practice, providing actionable recommendations for stakeholders aiming to optimize wood valorization waste systems. These recommendations emphasize the necessity for a holistic approach and a clearly defined, comprehensive framework for wood valorization that considers all elements involved in the process. …”
Get full text

Optimality Theory in Egyptian Arabic Phonological Acquisition by Mona Maamoun

Get full text

Transcutaneous and transcranial electrical stimulation for enhancing military performance: an update and systematic review by Onno van der Groen, Sara A. Rafique, Nick Willmot, Margaret G. Murphy, Margaret G. Murphy, Eulalia Tisnovsky, Tad T. Brunyé, Tad T. Brunyé

“…While tES and tVNS showed some promise for enhancing multitasking and visual search performance, the results were mixed, with no reliable effects on vigilance tasks.DiscussionThe reviewed studies highlight the need for a better understanding of ES mechanisms, optimal stimulation parameters, and individual differences in response to ES. …”
Get full text

Multi-Objective Optimization Methods for University Campus Planning and Design—A Case Study of Dalian University of Technology by Lin Qi, Chaoran Chen, Jun Dong

“…Taking the northern residential area of the western campus of Dalian University of Technology as a case study, multiple Pareto-optimal solutions were generated. …”
Get full text

Study on the Design and Optimization of the Mix Proportion for High-Grade Concrete for the Pylon of a Long-Span Suspension Bridge by Xiaoliang Zhu, Baoan Quan, Sheng Fang, Hao Wei, Junchen Zhao

“…Through more than 20 sets of experiments, multistep optimization, and verification, the key factors and their mechanisms in mix proportion design were clarified.This study provides a systematic methodology and practical basis for the design of high-fluidity mass concrete, ensuring the safety and durability of projects.…”
Get full text