Is Topical Tranexamic Acid Effective in Reducing Hematoma and Seroma in Breast Surgery? A Systematic Review and Meta-analysis by Ammar S.A. Hashemi, MD, Sara M. Hussein, MD, Zainab H. Alshehab, Abdullah A. Al Qurashi, MD, Lucas Kreutz-Rodrigues, MD, Basel A. Sharaf, MD, DDS, FACS

“…However, evidence on the efficacy of topical TXA in breast surgery remains sparse. Methods:. This systematic review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. …”
Get full text

The effect of visual feedback on balance rehabilitation in people with impaired ankle instability: a systematic review and meta-analysis by Chuan qiu shui Wang, Kun Wang, Liang Sun, Shi qi Liu, Jiong Luo

“…However, inconsistencies exist in the scientific literature regarding the effect size of visual feedback and the optimal method of delivery. Aim The objective of this systematic review and meta-analysis was twofold: firstly, to conduct a comprehensive assessment of the potential impact of visual feedback on balance exercises for individuals with ankle instability; secondly, to quantify the effects of visual feedback on balance in this population. …”
Get full text

Efficacy and safety of GLP-1 agonists in the treatment of T2DM: A systematic review and network meta-analysis by Xiaoyu Ren, Honghao Hua, Yuanqin Wu, Wei Zhang, Xianzhen Long, Yana Bai, Ning Cheng

Get full text

Enhancing online learning: a systematic literature review exploring the impact of screencast feedback on student learning outcomes by Arathai Din Eak, Nagaletchimee Annamalai

“…Design/methodology/approach – This paper adopts a systematic review approach to synthesise and analyse existing studies investigating the use of screencast feedback in online higher education settings. …”
Get full text

Impact of Incomplete Percutaneous Revascularization in Patients With Multivessel Coronary Artery Disease: A Systematic Review and Meta‐Analysis by Vinayak Nagaraja, Sze‐Yuan Ooi, James Nolan, Adrian Large, Mark De Belder, Peter Ludman, Rodrigo Bagur, Nick Curzen, Takashi Matsukage, Fuminobu Yoshimachi, Chun Shing Kwok, Colin Berry, Mamas A. Mamas

Get full text

Chinese herbal injections in combination with radiotherapy for advanced pancreatic cancer: A systematic review and network meta-analysis by Yun-Ru Chen, Ruo-Tong Zhao, Yi-Fang Xu, Yin-Jie Ma, Shao-Bo Hu, Xue-Hui Wang, Bing-Bing Fan, Yan-Ji Zhou, Yu-Bei Huang, Nicola Robinson, Jian-Ping Liu, Zhao-Lan Liu

“…Background: Advanced pancreatic cancer (APC) is a fatal disease with limited treatment options. …”
Get full text

Does the surgeon’s learning curve impact pentafecta outcomes in radical prostatectomy? a systematic review and meta-analysis by Jose Arnaldo Shiomi Da Cruz, Breno Cordeiro Porto, Bruno Damico Terada, Felipe Giraldo Alvarez Gonçalves, Soraya Hussein Orra, Juan Victor Nabhan Martinez, Carlo Camargo Passerotti, Rodrigo A. S. Sardenberg, Kenneth Nunes Tavares De Almeida, Everson Luiz De Almeida Artifon, Jose Pinhata Otoch

“…Materials and methods A systematic review of MEDLINE, Embase, Scopus, Web of Science, and Google Scholar was conducted up to March 2024, focusing on learning curves in prostatectomy. …”
Get full text

Early Flap Reconstruction and Infection Rates in Open Lower Extremity Fractures: A Systematic Review and Meta-analysis by Rafael Felix P. Tiongco, BA, Siam K. Rezwan, BA, Sami Alahmadi, MSc, Matthew J. Heron, BS, Scott A. Sylvester, MD, Stella M. Seal, MLS, Tim de Jong, MD, PhD, Ala Elhelali, PhD, MSc, Lily R. Mundy, MD

Get full text

Cognitive and Motor Function Effects of Antipsychotics in Traumatic Brain Injury: A Systematic Review of Pre-Clinical Studies by Gabrielle Cataford, Laurie-Anne Monton, Stephanie Karzon, Camille Livernoche-Leduc, Mar Saavedra-Mitjans, Marie-Julie Potvin, Francis Bernard, Lisa Burry, Caroline Arbour, David R. Williamson

“…Despite their frequent use, there have been no large randomized controlled studies of antipsychotics for the management of agitated behaviors during the acute TBI recovery period. We conducted a systematic review and meta-analysis of pre-clinical studies evaluating the effects of antipsychotics post-TBI on both cognitive and motor recovery. …”
Get full text

Oral health-related knowledge, attitudes and behaviors (KAB) of dental students: a systematic review and meta-analysis by Xiaochen Jiang, Fei Wang, Weifeng Wang, Wenjuan Cao, Xueling Qiu, Chenxi Sun, Fan Sun, Lu Tang

Get full text

Factors contributing to bracing success in juvenile idiopathic scoliosis and current limitations: a systematic review and meta-analysis by Kai Him Ambrose Chan, Kai Chun Augustine Chan, Elijah Maliwat, Jason Pui Yin Cheung, Prudence Wing Hang Cheung

Get full text

The efficacy and safety of nanoemulsion compared to conventional cyclosporine in dry eye disease: A systematic review and meta-analysis by Afaf Bachira Gouhiri, Mohamed A. Aldemerdash, Naila-Oulfet Zitouni, Zina Otmani, Omar F. Abbas, Weam Aldiban, Youssef Adel Youssef Ashmawi, Abdelaziz A Awad, Hashem Abu Serhan

“…Purpose: To evaluate the efficacy and safety of nanoemulsion cyclosporine compared to conventional cyclosporine in reducing symptoms of dry eye disease (DED). Design: A systematic review and meta-analysis. Methods: We searched Scopus, Web of Science, PubMed, Embase, and Cochrane for relevant randomized clinical trials (RCTs) and pooled the mean differences (MD) for continuous efficacy outcomes, including the Schirmer test, ocular surface disease index (OSDI), and tear film break-up time (TBUT), and risk ratios (RR) for dichotomous safety outcomes, such as adverse drug reactions or ocular adverse events, with their corresponding 95% confidence intervals (CI) across different time points from baseline. …”
Get full text

Wearable sensor use for assessing standing balance and walking stability in people with Parkinson's disease: a systematic review. by Ryan P Hubble, Geraldine A Naughton, Peter A Silburn, Michael H Cole

“…Articles were excluded if they; i) did not use any form of wearable sensor to measure variables associated with standing balance or walking stability; ii) did not include a control group or control condition; iii) were an abstract and/or included in the proceedings of a conference; or iv) were a review article or case study. …”
Get full text

Surgical versus non-surgical treatment for vertebral compression fracture with osteopenia: a systematic review and meta-analysis. by Jia-Bao Guo, Yi Zhu, Bing-Lin Chen, Bin Xie, Wen-Yi Zhang, Yu-Jie Yang, Yu-Shan Yue, Xue-Qiang Wang

“…<h4>Methods</h4>We conducted a systematic search through electronic databases from inception to June 2014, with no limits on study data or language. …”
Get full text

Neurofilament Light Chain in Cerebrospinal Fluid and Blood in Multiple System Atrophy: A Systematic Review and Meta-Analysis by Silvia Demiri, Dimitra Veltsista, Vasileios Siokas, Kanellos C. Spiliopoulos, Antonia Tsika, Polyxeni Stamati, Elisabeth Chroni, Efthimios Dardiotis, Ioannis Liampas

“…<b>Background/Objectives</b>: Multiple system atrophy (MSA) presents a challenging diagnosis due to its clinical overlap with other neurodegenerative disorders, especially other α-synucleinopathies. …”
Get full text

A systematic review and meta-analysis of the effectiveness of perineural dextrose injection in peripheral compression neuropathies of the upper limbs by Fatemeh Azizi, Faezeh Saber Gharesoo, Fereshteh Eidy, Sama Heidari, Nastaran Maghbouli, Shirin Djalalinia, Amir Kasaeian

“…Dextrose 5 % water injection has emerged as a potential therapy by reducing inflammation and promoting tissue regeneration. …”
Get full text

Sarcopenia defined by multidimensional factors and its prognostic role in heart failure: a systematic review and meta-analysis by Jinmei Lu, Yi Gao, Lingbo Zhou, Xinhui Peng, Haiming Feng, Zaixing Zheng

“…Clinically, adopting multidimensional diagnostic approaches can improve risk stratification and optimize the management of HF patients.Systematic review registrationhttps://inplasy.com/inplasy-2025-3-0023/, identifier INPLASY202530023.…”
Get full text

THE IMPACT OF SARCOPENIA ON POSTOPERATIVE OUTCOMES IN ESOPHAGEAL CANCER PATIENTS UNDERGOING ESOPHAGECTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS by Yurii M. Kondratskyi, Yevhenii A. Shudrak, Andrii V. Horodetskyi, Oleksii Y. Dobrzhanskyi, Mykyta O. Pepenin, Yurij A. Dibrova, Andrii V. Kolesnyk

“…Materials and methods. A systematic literature search was conducted in MedLine and Cochrane Library Central for studies published between January 2020 and September 2024, adhering to PRISMA guidelines. …”
Get full text

Anti-Platelet Therapy with Cangrelor in Cardiogenic Shock Patients: A Systematic Review and Single-Arm Meta-Analysis by Jacopo D’Andria Ursoleo, Luca Baldetti, Marina Pieri, Pasquale Nardelli, Savino Altizio, Silvia Ajello, Anna Mara Scandroglio

“…<i>Materials and Methods:</i> In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we performed a systematic review and single-arm meta-analysis of the safety and efficacy outcomes (i.e., rates of major bleeding, occurrence of stent/any thrombosis, and hospital survival) of all existing original studies reporting on the intravenous administration of cangrelor in AMI-CS patients. …”
Get full text

The Impact of Exercise Training on the Brain and Cognition in Type 2 Diabetes, and its Physiological Mediators: A Systematic Review by Jitske Vandersmissen, Ilse Dewachter, Koen Cuypers, Dominique Hansen

“…Conclusion Overall, exercise training beneficially affects cognition and brain structure and function in T2DM, with resistance and endurance exercise having similar effects. However, there is a need for additional studies, and more methodological consistency between different studies in order to define an exercise program optimal for improving cognition in T2DM. …”
Get full text