In Vitro Structure–Activity Relationship Stability Study of Antisense Oligonucleotide Therapeutics Using Biological Matrices and Nucleases by Jelena Lovrić, Jingjing Yan, XueQing Li, Tony Karlsborn, Mattias Bood, Anders Dahlén, Constanze Hilgendorf, Deepak Kumar Bhatt

“…Employing nucleases and comparing stability data with matrices of animal origin holds promise for a future fast‐track assessment of drug stability, enabling the efficient selection of optimal drug candidates for subsequent in vivo studies.…”
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Harnessing artificial intelligence of things for cardiac sensing: current advances and network-based perspectives by Hao Ren, Hao Ren, Hao Ren, Fengshi Jing, Yongcong Ma, Ruining Wang, Chaocheng He, Yufan Wang, Jiandong Zhou, Yu Sun

“…A total of 2,128 papers were included in the analysis.ConclusionFrom our perspective, current advancements in AI-powered IoT cardiac sensors primarily focus on optimizing AI algorithms, such as deep learning techniques, and enhancing the functionality of smart wearable devices for precision medicine. …”
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Mechanical Characterization of Porous Bone-like Scaffolds with Complex Microstructures for Bone Regeneration by Brandon Coburn, Roozbeh Ross Salary

“…The objective of this study is to systematically investigate the mechanical performance of SimuBone, a medical-grade biocompatible and biodegradable material, using 10 distinct triply periodic minimal surface (TPMS) designs with various internal structures. …”
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Plasma characterization and modulation techniques for 1.3 GHz, 9-cell superconducting rf cavity cleaning by Tongtong Zhu, Xinghai Bao, Yuan He, Zongheng Xue, Yubo Qiu, Chunlong Li, Wentian Xue, Tiancai Jiang, Qingwei Chu, Hao Guo, Shichun Huang, Ziqin Yang, Weiming Yue, Jinfang Chen, Mengxin Xu, Shenghu Zhang, Kun Zhang, Hongwei Zhao, Teng Tan, Andong Wu

“…Subsequently, the effects of power, gas pressure, and frequency on the physical properties of the plasma are systematically analyzed. Among these, the 640 nm spectral line was selected as a qualitative indicator of glow intensity and plasma state changes within the cavity due to its strongest peak intensity. …”
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An Analysis of Layer-Freezing Strategies for Enhanced Transfer Learning in YOLO Architectures by Andrzej D. Dobrzycki, Ana M. Bernardos, José R. Casar

“…This research addresses this gap by presenting a detailed analysis of layer-freezing strategies. …”
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Machine learning models integrating intracranial artery calcification to predict outcomes of mechanical thrombectomy by Guangzong Li, Yuesen Zhang, Di Li, Manhong Zhao, Lin Yin

“…Preoperative clinical and radiological data, including a quantitative assessment of IAC, were systematically collected. …”
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Interactive Relationship between Rail Transit and Industrial Development in Beijing by WANG Jing, ZHANG Jian, XU Wencong

“…[Method] Taking Beijing as a typical case for analysis, the current rail transit operation status in Beijing and its primary conflicts with industrial development are systematically examined. …”
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Hydrogen-bonding induced assembly of polymer-grafted nanoparticles towards photothermal antibacterial activities by Simeng Liu, Zhuo-Ran Yang, Yinhan Xu, Mengmeng Zhang, Hao Jiang, Jiangping Xu, Jintao Zhu

“…Their thermal-responsive assembly behavior in an organic solvent was systematically studied. By optimizing the assembly conditions, i.e., the concentration of PGNPs and the incubation time, the assemblies of AuNP@PS-Thy/AuNP@PS-Dap with controllable size were obtained. …”
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Enhancing nucleic acid delivery by the integration of artificial intelligence into lipid nanoparticle formulation by Kagya Amoako, Amir Mokhammad, Afrida Malik, Sumith Yesudasan, Anas Wheba, Oluwanifemi Olagunju, Sean X. Gu, Sean X. Gu, Timur Yarovinsky, Edward Vincent S. Faustino, Juliane Nguyen, John Hwa

“…This review explores the evolution and design of LNPs, focusing on their role in hematologic therapies and platelet transfection, where unique challenges arise due to platelets’ anucleate nature. The paper systematically evaluates the composition of LNPs, highlighting the role of ionizable, cationic, and neutral lipids in optimizing delivery efficiency, stability, and immune response modulation. …”
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Viral etiology of severe acute respiratory infections in hospitalized patients, Shandong, China. by Chunwang Li, Yujie He, Xiao Pan, Huimin Yin, Yaowen Pei, Shaoxia Song, Lin Sun, Shu Zhang, Julong Wu, Zhong Li, Xianjun Wang, Zengqiang Kou, Lei Zhao, Weijia Xing, Ti Liu

“…<h4>Background</h4>Severe Acute Respiratory Infection (SARI) represents a critical global public health challenge, accounting for substantial severe morbidity and hospitalization burdens with distinct geographical patterns in etiological profiles. …”
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Experimental Investigation and Molecular Dynamics Modeling of the Effects of K₂O on the Structure and Viscosity of SiO₂-CaO-Al₂O₃-MgO-K<... by Fan Yang, Qingguo Xue, Haibin Zuo, Yu Liu, Jingsong Wang

“…The results revealed a rapid 52% decrease in slag viscosity and an 18.32 kJ/mol reduction in activation energy as K₂O content increased from 0% to 3%. …”
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Comparative analysis of hull steel corrosion in tropical marine atmosphere: Correlation between indoor simulations and outdoor exposures by Feng Gao, Caifu Yang, Weiyi Wang, Yajun Pang, Naipeng Zhou, Jian Li, Xiaobing Luo, Feng Chai

“…This study systematically investigates the corrosion behavior of hull steel in a tropical marine atmospheric environment through a combination of indoor simulation and outdoor exposure tests. …”
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Effect of extraction temperature on value-added biopolymer recovery in waste activated sludge by Yingjie Yang, Hao Zhou, Wanliang Liu, Kun Wang, Tong Yu

“…Fluorescence spectroscopy also indicated a pronounced increase in aromatic protein-like substances (C1), whereas polysaccharides showed a comparatively modest increase. …”
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AgNPs@CeO₂/Nafion Nanocomposite-Modified Electrode for the Sensitive Detection of Trace Lead (II) in Water Samples by Zhengying Guo, Peng Xu, Shiqing Zhou, Ruoxi Wu

“…Consequently, the accurate and rapid detection of heavy metal ions is critically important. A AgNPs@CeO₂/Nafion composite was prepared by dispersing nano-ceria (CeO₂) in a Nafion solution and incorporating silver nanoparticles (AgNPs). …”
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Sampling strategies for digestive system flora studies: current research and perspectives by Xiaobo Liu, Xia Cheng, Ziye Gao, Jun Pan, Shizhen Luo, Pei Liu, Hui Wen, Shu Jin

“…Methodology We conducted a comprehensive literature review using professional databases such as PubMed and Web of Science. …”
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The Effect of α-Al(MnCr)Si Dispersoids on Activation Energy and Workability of Al-Mg-Si-Cu Alloys during Hot Deformation by Xiaoguo Wang, Jian Qin, Hiromi Nagaumi, Ruirui Wu, Qiushu Li

“…The evolution of the activation energies of two alloys was investigated on a revised Sellars’ constitutive equation. The processing maps and activation energy maps of both alloys were also constructed to reveal deformation stable domains and optimize deformation parameters, respectively. …”
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Production and characterization of sophorolipid under yeast-mediated submerged fermentation utilizing Agro-industrial waste by Aishwary Purohit, Amar Jyoti Das, Debashish Ghosh

“…By systematically optimizing strain adaptation, medium composition, and scaling up the process from shake flasks to a bioreactor, a maximum sophorolipid yield of 2.6 ± 0.21 g/L was achieved. …”
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Repetition Frequency-Dependent Formation of Oxidized LIPSSs on Amorphous Silicon Films by Liye Xu, Wei Yan, Weicheng Cui, Min Qiu

“…Laser-induced periodic surface structures (LIPSSs) produced via ultrafast laser-induced oxidation offer a promising route for high-quality nanostructuring, with reduced thermal damage compared to conventional ablation-based methods. …”
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Effects of Phytogenic Feed Additive on Production Performance, Slaughtering Performance, Meat Quality, and Intestinal Flora of White-Feathered Broilers by Jianming Ren, Siyu Ren, Haochi Yang, Peng Ji

“…This study systematically evaluates the effects of dietary supplementation with phytogenic feed additive (0.2%, 0.4%, and 0.8%) on white-feathered broilers (n = 88) through a 42-day controlled trial with the weight of approximately 50 g. …”
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Enhancing Steamed Bread Quality Through Co-Fermentation of Sourdough with <i>Kazachstania humilis</i> and <i>Lactobacillus plantarum</i> by Zicheng Wang, Ao Fu, Xin Wang, Guohua Zhang

“…Sourdough fermentation, a time-honored biotechnology known for enhancing the texture, flavor, and nutritional quality of steamed bread, has yet to be fully leveraged for optimizing microbial synergy, particularly between <i>Kazachstania humilis</i> (KH) and <i>Lactobacillus plantarum</i> (LP). …”
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