Integrating analytical quality by design into bioanalytical method development: an HPLC-FLD method for quantification of alectinib in biological matrix by Eun Ji Lee, Nahyun Koo, Min Ju Kim, Kyeong-Ryoon Lee, Yoon-Jee Chae

“…Critical method parameters, including the organic phase ratio, buffer concentration, and flow rate, were identified through Failure Mode and Effects Analysis, and optimized using a Box–Behnken design. The final method exhibited excellent linearity (R² >0.99) over a concentration range of 5–1,000 ng/mL, with a lower limit of quantification of 5 ng/mL. …”
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Spectroscopic Quantification of Metallic Element Concentrations in Liquid-Propellant Rocket Exhaust Plumes by Siyang Tan, Song Yan, Xiang Li, Tong Su, Qingchun Lei, Wei Fan

“…This paper develops a hybrid method combining atomic emission spectroscopy (AES) theory with a genetic algorithm (GA) optimized backpropagation (BP) network to quantify the metallic element concentrations in liquid-propellant rocket exhaust plumes. …”
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Mass and Heat Balance Model and Its Engineering Application for the Oxygen Blast Furnace Smelting Process of Vanadium–Titanium Magnetite by Yun Huang, Mansheng Chu, Xian Gan, Shushi Zhang, Zhenyang Wang, Jianliang Zhang

“…The results show that increasing the pulverized coal injection ratio slightly reduces productivity and theoretical flame temperature: for every 25 kg/tHM increase in the coal ratio, the theoretical flame temperature decreases by 21.95 °C; moreover, indirect reduction is enhanced and the heat distribution within the furnace is significantly improved. A higher recycling gas volume markedly increases productivity and optimizes hearth thermal conditions, accompanied by enhanced blast kinetic energy and an expanded tuyere raceway zone, albeit with a notable drop in combustion temperature. …”
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Effect of segregation on hot deformation behavior of GCr15 bearing steel in continuous casting by Mingyang Liu, Tianyu Zhang, Chenchong Wang, Ye Liu, Junyang Qian, Hongshuang Di, Qing Yin, Chi Zhang

“…Based on these observations, the optimal hot processing conditions were identified as a deformation temperature of 1000 °C and a strain rate of 0.1 s−1.…”
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Potential impacts of acupuncture on motor function recovery after ischemic stroke: insights from basic and clinical studies by Jia-Ling He, Liang-Xiao Ma, Liang-Xiao Ma, Jing-Si Wen, Yu-Xin Zhuang, Xu Qian, Ling-Hui Ma, Jing-Yun Xiu, Xiu-Yan Wang, Meng-Yu Chen

“…This review systematically evaluates existing basic and clinical studies to explore the potential mechanisms of acupuncture’s effects on motor function recovery after ischemic stroke and the optimal clinical strategies. …”
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High-level production of free fatty acids from lignocellulose hydrolysate by co-utilizing glucose and xylose in yeast by Xin Ni, Jingjing Li, Wei Yu, Fan Bai, Zongbao K. Zhao, Jiaoqi Gao, Fan Yang, Yongjin J. Zhou

“…The non-oxidative branch of the pentose phosphate pathway, and the adaptive expression levels of xylose metabolic pathway genes XYL1, XYL2 and XYL3, were systematically optimized. In addition, the introduction of xylose transporter and global regulation of transcription factors achieved synchronous co-utilization of glucose and xylose. …”
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Evaluating the performance of personality-based profiling in predicting physical activity by Kentaro Katahira, Keisuke Takano, Takeyuki Oba, Kenta Kimura

“…Abstract Background Profiling or clustering individuals based on personality and other characteristics is a common statistical approach used in marketing, medicine, and social sciences. …”
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High-Performance Low-Bandgap Polymer Solar Cells With Optical Microcavity Employing Ultrathin Ag Film Electrode by Ning Li, Dazheng Chen, Chunfu Zhang, Jingjing Chang, Zhenhua Lin, Genquan Han, Jincheng Zhang, Lixin Guo, Yue Hao

“…Further, enhanced performance is obtained from an optimizing top-illuminated device. It is noted that a remarkably enhanced short-circuit current density of 19.50 mA/cm² is achieved for the microcavity device at optimized layer thicknesses, which is 11% higher than that of ITO-based devices. …”
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Comprehensive Review of Plant Protein Digestibility: Challenges, Assessment Methods, and Improvement Strategies by Mauricio Opazo-Navarrete, César Burgos-Díaz, Cristina Bravo-Reyes, Ivo Gajardo-Poblete, Manuel Chacón-Fuentes, Juan E. Reyes, Luis Mojica

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Dynamic evolution of multidimensional quality characteristics in Lactobacillus-fermented Polygonatum sibiricum Red. and Crataegus pinnatifida Bunge Jiaosu by Yan-Li Ma, Yin-Zhuang Wang, Hai-Yan Yang, Ding-Ding Duan, Yan-Ping Shi, Jun Wang

“…These findings provide a novel strategy for precision fermentation of dual-plant Jiaosu with optimized functional and sensory properties.…”
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Plant Growth-Promoting Rhizobacteria Enhance Sweet Cherry Root System Development Through the Production of Volatile Organic Compounds by Nan Zeng, Rutao Gai, Dandan Wang, Jiahe Pang, Dingcun Zhang, Junliang Ge, Xinyue Bi, Zhiyong Zhang, Ning Zhang, Bingxue Li

“…This study establishes the strain-concentration–effect relationship, providing a theoretical foundation to optimize soil microbial environments and promote cherry root development using PGPR.…”
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Evaluation of Advances in Battery Health Prediction for Electric Vehicles from Traditional Linear Filters to Latest Machine Learning Approaches by Adrienn Dineva

“…The review then evaluates recent advancements in Machine Learning (ML) and Artificial Intelligence (AI) techniques, emphasizing their contributions to improving SOH estimation. Through a rigorous screening process, the paper systematically assesses the evolution of these advanced methods, addressing specific research questions to evaluate their effectiveness and practical implications. …”
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Microstructures and Wear Behavior of Nickel - Coated Graphite/NiCrW Alloy Composite by DUAN Zhao - yu, LI Chang - sheng, KAI Shao - sen, LI Jian

“…When the content of nickel - plated graphite was 3%(mass fraction), the as - obtained NiCrW/graphite composites possessed the optimal tribological properties, which had 0.27 of friction coefficient and 3.2×10-5 mm3/(N·m) of wear rate.…”
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The subtle power of nonverbal communication in EFL classrooms: An observational study on teachers' gestures and students' comprehension by Mohammad Al-khresheh

“…The study employed a purposive sample of 12 university EFL teachers and their students. …”
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Immune Reconstitution after Haploidentical Hematopoietic Stem Cell Transplantation with Different Non‐T‐Cell Depletion Protocols by Xiao‐Di Ma, Zheng‐Li Xu, Xiao‐Jun Huang

“…Clinical studies and multiomic analyses have revealed that different protocols offer distinct mechanisms for IR patterns and further influence clinical outcomes. However, there is a lack of comprehensive reviews that systematically link the differences in IR between two protocols to their clinical outcomes, which leaves a critical gap in understanding the optimal strategies for IR in haplo‐HSCT. …”
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Variation in Nanocrystalline Phase Content on Mechanical Properties and Wear Resistance of FeCrMoWBRE Amorphous/Nanocrystalline Coating Deposited by High-Velocity Arc Spraying by Hao Du, Wei Xin, Bo Wang, Ji’an Feng, Xingchuan Xia, Yujiang Wang, Shicheng Wei

“…The coating with optimized nanocrystalline phase content of 21.4% exhibits the lowest wear rate of 1.39 × 10⁻⁷ mm³·N⁻¹·m⁻¹ under a 100 N load and oil lubrication. …”
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Impact of Input Image Resolution on Deep Learning Performance for Side-Scan Sonar Classification: An Accuracy–Efficiency Analysis by Xing Du, Yongfu Sun, Yupeng Song, Wanqing Chi, Lifeng Dong, Xiaolong Zhao

“…In conclusion, strategically reducing SSS image resolution based on application-specific accuracy requirements is a viable approach for optimizing computational resources. …”
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Unraveling the Impact of Copper Ions on Mineral Surfaces During Chalcopyrite–Molybdenite Flotation Separation Using Sodium Thioglycolate by Feng Jiang, Shuai He, Jiaxing Qi, Yuanjia Luo, Honghu Tang

“…However, the underlying impact mechanisms remain unclear. This study systematically investigated the influence of Cu²⁺ on the flotation separation of chalcopyrite and molybdenite, with sodium thioglycolate (STG) as a depressant. …”
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Correlation Method of Assistance Driving Function and Road Environment Factors in Investigation of Intelligent Vehicle Traffic Accident by Yanbin Hu, Wenhui Zhou

“…Through this rigorous process, 59 accident factors were refined and optimized, culminating in a method for assessing the degree of interference posed by road environment factors in traffic accidents involving assisted driving vehicles. …”
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Decoding RNA–Protein Interactions: Methodological Advances and Emerging Challenges by Wenkai Yi, Jian Yan

“…Over the past decade, significant advancements in methodologies have transformed the ability to study these interactions with unprecedented resolution and specificity. This review systematically compares RNA‐ and protein‐centric approaches, highlighting their strengths, limitations, and optimal applications. …”
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