Showing 7,021 - 7,040 results of 8,685 for search 'a systematic optimization', query time: 0.24s Refine Results
  1. 7021

    Flash‐Thermal Reduction of Graphene Oxide with Flexible Electronics Platform for Highly Sensitive Wearable Temperature Sensor by Yeong Jun Yun, Hyun Jin Kang, Chan Yun Bae, Gyu Heon Bae, Hyun Jin Lee, Ki Hoon Kim, Yeong Jun Jang, Tae Won Nam, Jung Woo Lee

    Published 2025-07-01
    “…The optimized flash‐thermal reduced graphene oxide based sensor exhibits exceptional flexibility, reversibility, high sensitivity (≈1.28% °C−1), excellent linearity (R2 ≈ 0.999), long‐term stability, and a rapid response time (≈0.6 s), outperforming conventional metal‐based temperature sensors in sensitivity. …”
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  2. 7022

    Yunnan Baiyao (YNBY): pharmacological mechanisms, therapeutic applications, and clinical evidence by Hongjing Qian, Hongjing Qian, Wanli Zhang, Wanli Zhang, Mingzhu Zhang, Mingzhu Zhang, Sijia Ma, Sijia Ma, Manhong Zhen, Manhong Zhen, Hongbing He, Hongbing He, Xiaobin Ren, Xiaobin Ren

    Published 2025-07-01
    “…However, existing studies have limitations such as inconsistent trial design and insufficient long-term safety data. This study provides a theoretical basis for optimizing the clinical application of YNBY, and points out future research directions, including the identification of active ingredients, the development of targeted delivery systems, and the development of large-scale randomized controlled trials.…”
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  3. 7023

    Air pollution’s toll on adverse birth outcomes: key research insights from Chinese epidemiological studies by Hui Chang, Hui Chang, Hui Chang, Wanting Sun, Yuanyuan Tian, Yuanyuan Tian, Jing Wu, Yanru Yue, Yanru Yue, Wenhua Li, Wenhua Li, Xin Zhao, Xin Zhao, Xiaoan Zhang, Jian Jin, Jian Jin

    Published 2025-07-01
    “…Despite extensive global evidence linking air pollution to adverse birth outcomes, a comprehensive synthesis of China-specific epidemiological insights—particularly across its regionally diverse pollution landscapes and susceptible populations—remains limited. …”
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  4. 7024

    Spatiotemporal Dynamics of Macrobenthic Communities and Environmental Factors in the Aquatic Vegetation Restoration Zone of Baimao Bay by Weiwei Wei, Ning Hu, Chunhua Li, Chun Ye, Kexin Miao, Yang Wang, Xian Xiao, Yuan Zhao, Youde Yang, Liangkui Lai

    Published 2025-05-01
    “…Lake Taihu, China’s third-largest freshwater lake, faces severe eutrophication challenges and therefore requires innovative ecological restoration strategies. This study systematically evaluates the ecological effects of aquatic vegetation restoration in Baimao Bay through comprehensive analysis of macrobenthic communities and environmental parameters, demonstrating significant water quality improvements including a 42.9% decrease in total phosphorus, a 69.4% decline in chl-a concentration, a 34.8% reduction in ammonium nitrogen, and a 81.2% increase in water transparency. …”
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  5. 7025

    Impact of SiO2 content on the hydrogen based direct reduction performance of high-grade hematite pellets by Bohua Li, Deqing Zhu, Zhengqi Guo, Jian Pan, Congcong Yang, Siwei Li

    Published 2025-07-01
    “…In this study, high-grade hematite oxidized fired pellets with a basicity (CaO/SiO2) of 0.3 were prepared, and the SiO2 content was systematically varied from 1.0 % to 4.0 %. …”
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  6. 7026

    Long-term stability strategies of deep brain flexible neural interface by Shiya Lv, Zhaojie Xu, Fan Mo, Yu Wang, Yiming Duan, Yaoyao Liu, Luyi Jing, Jin Shan, Qianli Jia, Mingchuan Wang, Siyu Zhang, Yu Liu, Juntao Liu, Jinping Luo, Yirong Wu, Mixia Wang, Yilin Song, Xinxia Cai

    Published 2025-05-01
    “…However, chronic inflammatory responses caused by long-term implantation and the resulting electrode failure seriously hinder the clinical development of this technology. This review systematically explores the long-term stability issues of flexible deep brain neural interfaces, with a focus on analyzing the synergistic optimization of electrode geometric morphology and implantation strategies in regulating inflammatory responses. …”
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  7. 7027

    MicroRNAs in anthracycline cardiotoxicity: biomarkers, mechanisms, and therapeutic advances by Hongyun Mao, Hongyun Mao, Jing Hu, Chenshuo Yu, Sicong Xie, Cheng Chang, Juanjuan Peng, Yang Zhang

    Published 2025-08-01
    “…MicroRNAs (miRNAs), as key post-transcriptional regulators of gene expression, play a pivotal role in the pathophysiology of cardiovascular disease, but their specific functions in anthracycline-induced cardiotoxicity (AIC) require systematic elucidation.PurposeThis review aims to systematically summarize current research on the key miRNAs, their molecular targets, and associated signaling pathways that regulate AIC, while also exploring their potential as biomarkers for early diagnosis and as therapeutic targets for intervention.MethodsA comprehensive literature search was conducted in PubMed, Web of Science, and Scopus databases for relevant studies published up to April 2025. …”
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  8. 7028

    Recent progress in calcium carbonate nanoparticles for cancer therapy: design strategies and clinical prospects by Xi Deng, Mohammad Yusuf Zanna, Hamidu Ahmed, Norsharina Ismail, Kim Wei Chan, Norhaizan Mohd Esa, Ahmad Faizal Abdull Razis, Md Zuki Abu Bakar, Zhongming Yang

    Published 2025-01-01
    “…By addressing these challenges, CaCO _3 NPs could become a valuable tool for targeted cancer therapy, offering enhanced treatment efficacy with reduced side effects.…”
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  9. 7029

    Hybrid causal inference framework for long-chain drought propagation networks: Combining convergent cross-mapping and generalized random forest by Jiayou Wang, Zhi Li, Yaning Chen, Shiru Han, Lingxin Kong

    Published 2025-09-01
    “…The hydrological cycle in inland river basins of arid regions operates as a closed system with diverse recharge sources. …”
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  10. 7030

    Clinical efficiency of exogenous L-arginine in patients with essential hypertension against the background of chronic obstructive pulmonary disease by O. V. Kraidashenko, O. S. Tiahla

    Published 2019-12-01
    “…All patients of the main group took L-arginine aspartate in the form of a 4.2 % solution intravenously, 100 ml 1 time per day (course of 10–12 days) with the subsequent transfer to the solution for oral administration of 10 ml 5 times a day (course of 3 months ± 3 days). …”
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  11. 7031

    Bibliometric analysis and knowledge mapping of diabetes mellitus combined with tuberculosis research: trends from 1995 to 2023 by Yufeng Li, Yufeng Li, Yufeng Li, Ruizi Ni, Yajing An, Ling Yang, Zhaoyang Ye, Li Zhuang, Linsheng Li, Liang Wang, Liang Wang, Wenping Gong, Wenping Gong

    Published 2025-04-01
    “…Keyword evolution revealed three transformative phases: (1) Pathomechanistic exploration (1995-2016): Focused on hyperglycemia-immunity interplay and epidemiological surveillance; (2) Translational innovation (2017-2020): Shifted to preclinical models, pharmacokinetic optimization, and multidrug resistance; (3) Precision medicine era (2021-2023): Emerging hotspots in latent TB screening (burst strength=6.82), metformin-mediated immunomodulation, and AI-driven diagnostic biomarkers.ConclusionBeyond delineating historical trajectories, this study identifies critical knowledge gaps in inflammation-resolution mechanisms and insulin resistance pathways, proposing a roadmap for targeted biomarker discovery and global health policy formulation. …”
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  12. 7032

    Forward Predicting Chromatic-Optical Parameters of the Mixed Light of White-Red Light-Emitting Diode Configurations Based on Deep Learning Algorithms by Songsheng Lin, Huanting Chen, Yin Zheng, Quanji Xie, Xuehua Shen, Huichuan Lin, Shuo Lin, Yan Li

    Published 2025-01-01
    “…The heatsink temperature, white LED driving current, and red LED driving current were each varied systematically to generate a comprehensive set of 5,166 spectral power distribution (SPD) measurements. …”
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  13. 7033

    Comparative Analysis of Habitat Expansion Mechanisms for Four Invasive <i>Amaranthaceae</i> Plants Under Current and Future Climates Using MaxEnt by Mao Lin, Xingzhuang Ye, Zixin Zhao, Shipin Chen, Bao Liu

    Published 2025-08-01
    “…By coupling multi-species comparative analysis with a parameter-optimized Maximum Entropy (MaxEnt) model integrating climate, soil, and topographical variables in China under Shared Socioeconomic Pathways (SSP) 126/245/585 scenarios, we reveal divergent expansion mechanisms (e.g., 247 km faster northward shift in <i>A. palmeri</i> than <i>D. ambrosioides</i>) that redefine invasion corridors in the North China Plain. …”
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  14. 7034

    Hyperspectral Imaging for Detecting Plastic Debris on Shoreline Sands to Support Recycling by Roberta Palmieri, Riccardo Gasbarrone, Giuseppe Bonifazi, Giorgia Piccinini, Silvia Serranti

    Published 2024-12-01
    “…The study focused on three distinct beaches (i.e., Foce Verde, Capo Portiere, and Sabaudia), each characterized by a different type of sand. For each location, the adopted approach allowed for the systematic classification of the various types of plastic waste found. …”
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  15. 7035

    Tissue Distribution and Pharmacokinetic Characteristics of Aztreonam Based on Multi-Species PBPK Model by Xiao Ye, Xiaolong Sun, Jianing Zhang, Min Yu, Nie Wen, Xingchao Geng, Ying Liu

    Published 2025-06-01
    “…This study aimed to systematically characterize the plasma and tissue concentration-time profiles of aztreonam in rats, mice, dogs, monkeys, and humans by developing a multi-species, physiologically based pharmacokinetic (PBPK) model. …”
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  16. 7036

    Enhancing Methylene Blue Adsorption Performance of Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub>@Sodium Alginate Foam Through Pore Structure Regulation by Yi Hu, Hongwei Wang, Xianliang Ren, Fang Wu, Gaobin Liu, Shufang Zhang, Haijun Luo, Liang Fang

    Published 2024-11-01
    “…Their methylene blue (MB) adsorption performances were then systematically compared. The results revealed that the honeycomb-like porous-structured spherical foams have a significantly higher adsorption capacity than their lamellar counterparts. …”
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  17. 7037

    Comparative study of flow rate- and material-dependent human plasma protein adsorption on oxygenator membranes and heat exchanger materials by Katharina Große-Berkenbusch, Meltem Avci-Adali, Patrick Cahalan, Linda Cahalan, Ana Velic, Boris Maček, Christian Schlensak, Hans Peter Wendel, Sandra Stoppelkamp

    Published 2025-06-01
    “…Notably, at a low flow rate, PMP HFM exhibited a significant increase in binding of complement and inflammation inhibitors, suggesting a potential benefit of lowering the flow rate apart from the general reduction in protein adsorption.…”
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  18. 7038

    Challenges and Opportunities in Business Process Elicitation by Jorge Hochstetter-Diez, Marlene Negrier-Seguel, Claudio Navarro-Cruces, Mauricio Dieguez-Rebolledo, Marco Caceres-Senn, Yolanda Valdes-Rodriguez, Jeferson Arango-Lopez

    Published 2025-01-01
    “…Objectives: The primary goal is to identify and classify approaches and techniques used in process elicitation, categorizing them into key areas and assessing their impact on continuous improvement in organizations. Methodology: A systematic mapping was conducted to review existing literature, classifying selected studies into methodologies, modeling tools, and automation frameworks. …”
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  19. 7039

    Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines by Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang

    Published 2025-08-01
    “…First, the development, application potential, particularities, and limitations of CHMs are reviewed. Subsequently, a systematic and comprehensive analysis of the two nano‐strategies for optimizing CHMs are presented, highlighting the distinct characteristics of the carrier‐free and carrier‐based approaches. …”
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  20. 7040

    Use of Remote Assessment Tools to Substitute Routine Outpatient Care: Scoping Review by Jayne Barclay, Clair Sullivan, Michael Beckmann, Graeme Mattison, Rebecca Runciman, Elizabeth Martin

    Published 2025-03-01
    “…The objectives include assessing the extent of use, types, and effectiveness of these tools in substituting conventional outpatient care. MethodsA comprehensive scoping review was conducted, adhering to the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) checklist. …”
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