Focal Therapy for Prostate Cancer: Recent Advances and Insights by Francesco Lasorsa, Arianna Biasatti, Angelo Orsini, Gabriele Bignante, Gabriana M. Farah, Savio Domenico Pandolfo, Luca Lambertini, Deepika Reddy, Rocco Damiano, Pasquale Ditonno, Giuseppe Lucarelli, Riccardo Autorino, Srinivas Vourganti

“…The aim of this non-systematic review is to offer a comprehensive analysis of recently available evidence on focal therapy for PCa.…”
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The Strategies to use the Abandoned Agricultural Lands around Sanandaj by Reza Movahedi, Sina Javanmardi

“…Sample size is determined using Cochran formula (n = 357) and a systematic random method is used for sampling process. …”
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Comprehensive review of vibration-assisted welding processes: Mechanisms, applications, and future directions by Rajeev Ranjan, Robert Cep, Ashwini Kumar, Mayank Srivastava, Faisal Altarazi, Namrata Dogra, Ajay Kumar, Subhash Chand, S. P. Samal

“…The objective of this review paper is to provide a comprehensive and systematic analysis of the various aspects of vibration-assisted welding (VAW), focusing on its applications, limitations, future potential, and critical evaluations. …”
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Selection, Identification, and Application of Aptamers against Agaricus bisporus Lectin to Establish an Aptamer-AuNPs Colorimetric Method for Detection of ABL by Hao Gao, Yiling Tian, Min Zhang, Jianhui Liu, Yaowu Yuan, Jianxin Tan, Aijin Ma

“…One aptamer (seq-41) against ABL with a high affinity and specificity was isolated and demonstrated to be the optimal aptamer whose dissociation constant reaches the nanomolar level, Kd = 31.17 ± 0.1070 nM. …”
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CAR-T cell therapy clinical trials: global progress, challenges, and future directions from ClinicalTrials.gov insights by Li-Ya Cao, Yue Zhao, Yang Chen, Pan Ma, Jiang-Chuan Xie, Xin-Mei Pan, Xin Zhang, Yong-Chuan Chen, Qian Wang, Lin-Li Xie

“…Chimeric antigen receptor T (CAR-T) cell therapy has undergone vigorous development in recent years, yet it still faces significant challenges and difficulties in its clinical application and further development. A systematic synthesis of global trends in CAR-T clinical trials is essential to identify knowledge gaps, optimize treatment strategies, and guide future research directions. …”
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Specific Aspects of SELEX Protocol: Different Approaches for ssDNA Generation by Alexandr Garanin, Andrey Shalaev, Lidia Zabegina, Ekaterina Kadantseva, Tatiana Sharonova, Anastasia Malek

“…Systematic evolution of ligands by exponential enrichment (SELEX) is a technology for selecting functional aptamers that was first reported three decades ago and has been actively developed since. …”
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Design, synthesis, and biological evaluation of novel histone deacetylase 6 selective inhibitors by Tianyi Zhang, Xiaoyan Zhao, Xiangpei Sun, Wei Tian, Chongqing Wang, Mingping Wang, Yi Zhang, Xin Chen, Canhui Zheng

“…In this paper, on the basis of a Bcl-2/HDAC6 dual target inhibitor 7g reported by us previously, a novel type of HDAC6 inhibitors was obtained by removing the binding capability to Bcl-2 protein and the subsequent systematical optimization. …”
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Study on the Dynamic Characteristics of DM-DFBL Self-Delayed Feedback with an Optoelectronic Oscillation Loop by Nian Xie, Guangfu Bai, Yuanfen Li, Gang Kuang, Shu Xu, Daokai Huang, Xiaonan Wei, Qingzhe Wu, Weichao Huang

“…However, fiber-based optoelectronic feedback or pure optical feedback systems exhibit long delays, and the coupling mechanisms between these two loops differ significantly from those in short-delay systems. A systematic investigation of feedback coupling mechanisms under long-delay conditions is of great significance for optimizing such systems. …”
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Integrated vibration packing-sintering process for ITO rotary targets via slurry rheology and discrete element method simulations by Xiaokai Liu, Wenyu Zhang, Hetao Zhao, Benshuang Sun, Xina Liang, Bo Wei, Jiancun Ying, Huiyu Zhang, Yongge Zhao, Yongchun Shu, Yang Liu, Jilin He

“…Sintering experiments confirmed that the initial packing density influences the final sintering density. Through optimization of vibration frequency and sintering process, a large-size rotating ITO target with a density of 99.90 %, resistivity of 0.12 mΩ cm, average grain size of 5.33 μm, outer diameter of 156 mm, thickness of 13 mm, and height of 655 mm was successfully fabricated.…”
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Magnetization switching driven by magnonic spin dissipation by Won-Young Choi, Jae-Hyun Ha, Min-Seung Jung, Seong Been Kim, Hyun Cheol Koo, OukJae Lee, Byoung-Chul Min, Hyejin Jang, Aga Shahee, Ji-Wan Kim, Mathias Kläui, Jung-Il Hong, Kyoung-Whan Kim, Dong-Soo Han

“…Our systematic experiments and comprehensive analysis confirm that our findings are a result of magnonic spin dissipation, rather than external spin sources. …”
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Elaborately engineered Au(I)‐based AIEgens: Robust and broad‐spectrum elimination abilities toward drug‐resistant bacteria by Shuangling Deng, Zhen Peng, Fang Zhou, Guanqing Zhong, Zhen Cai, Xiaodong Tang, Changhuo Xu, Lei Zheng, Ben Zhong Tang, Jing Zhang

“…Through systematic screening, we identified an optimal AIEgen, called complex 5, which can rapidly discriminate between gram‐positive (G+) and gram‐negative bacteria (G−) bacteria, and exert robust and broad‐spectrum antimicrobial potency against diverse drug‐resistant bacterial strains, including those intractable to treat in clinic. …”
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Cassava (Manihot esculenta Crantz): its nutritional composition insights for future research and development in Ethiopia by Abraham Woru Borku

“…Consequently, it is essential to carry out a thorough evaluation of cassava’s production, processing, and utilization within the community to optimize and fully harness this plant as a viable food source in Ethiopia.…”
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Integrating Immunotherapy With Targeted Therapy: Evaluating Efficacy in NSCLC Treatment Through Computational Analysis of Gene Regulatory Networks by Pranabesh Bhattacharjee, Aditya Lahiri, Tanmay Sindhwani, Norman Peter Reeves, Aniruddha Datta

“…The most effective four-drug combination identified (Durvalumab + Lumakras + Ribociclib + Capivasertib) targets immune evasion, KRAS signaling, cell cycle regulation, and AKT activation, reducing tumor-promoting signals by 89.2% compared to the untreated state. This study provides a theoretical and mechanistic basis for combining immune checkpoint blockade with targeted therapies in NSCLC and demonstrates the utility of BN modeling in optimizing personalized, mutation-specific treatment strategies.…”
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Design and Evaluation of AgileBPM SDLC–An Agile SDLC for Business Process Management Systems by Roberto Davila-Campos, Manuel Mora, Paola Yuritzy Reyes Delgado, Sergio Galvan-Cruz, Gabriela Citlalli Lopez Torres

“…Business Process Management Systems (BPMS) are critical for enabling organizations to automate, monitor, and optimize their core processes. While agile software development approaches have transformed traditional systems engineering, their systematic application to BPMS development remains limited and underexplored. …”
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Effect of Cotton Stalk Biochar Content on the Properties of Cotton Stalk and Residual Film Composites by Zhipeng Song, Xiaoyun Lian, Junhui Ran, Xuan Zheng, Xufeng Wang, Xiaoqing Lian

“…A systematic investigation was conducted on the effect of biochar content on material properties. …”
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Evolutionary dynamics and antigenic diversity of porcine epidemic diarrhea virus (PEDV) in China: phylogenetic and recombination analyses based on large-scale S gene sequences by Yongjie Fu, Yingchun Wang, Liuliu Dai, Bimei Cheng, Shuqi Xiao, Yupeng Yin

“…In this study, we conducted a systematic analysis of the molecular characteristics and evolutionary dynamics of 1109 PEDV strains circulating in China, focusing on their S gene sequences. …”
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Characterization of Driver Dynamic Visual Perception Under Different Road Linearity Conditions by Zhenxiang Hao, Jianping Hu, Jin Ran, Xiaohui Sun, Yuhang Zheng, Chengzhang Li

“…Drivers’ visual characteristics have an important impact on traffic safety, but existing studies are mostly limited to single-scene analyses and lack a systematic study on the dynamic changes in drivers’ eye tracking characteristics on different road sections. …”
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The Effects of Global Climate Warming on the Developmental Parameters of <i>Helicoverpa armigera</i> (Hübner, 1808) (Lepidoptera: Noctuidae) by Zhiqian Liu, Biyu Liu, Huan Yu, Honghua Zhang, Zhipeng He, Zhihang Zhuo

“…In recent years, the severity of its damage has increased markedly, and its population dynamics and biological characteristics may be profoundly affected by global climate change. This study conducted a systematic meta-analysis to evaluate the life history traits of <i>H. armigera</i> under conditions of rising global temperatures, different photoperiods, and humidity levels. …”
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Application of PTFE composite catalytic filter material in synergistic purification of multiple pollutants in waste incineration flue gas by Chen Songxuan, Wang Hao, Yao Liang, Sun Zhi, Cao Hongbin

“…A systematic investigation of its performance and reaction mechanisms reveals that the coating process optimizes the pore structure of the filtration material. …”
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The Essence and Content of Product Distribution as an Economic Category by Viktoriia Bozhkova, Mykhailo Bilukha

“…Therefore, the proposed definition of the concept of “distribution” combines the key aspects of the definitions presented in the literature, conceptually reflects its essence and content with an emphasis on a systematic approach and covers marketing, logistics and commercial contexts.…”
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