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The novel inhaled dual PDE3 and PDE4 inhibitor ensifentrine for the treatment of COPD: A systematic review and meta-analysis protocol on trough FEV1 and exacerbation according to P...
Published 2024-01-01“…Additionally, subgroup analyses may unveil factors influencing the efficacy of ensifentrine, guiding optimal therapeutic strategies. Overall, this protocol holds the potential to inform clinical practice and regulatory decisions, positioning ensifentrine as a valuable addition to COPD management.…”
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2823
Ultra-rapid lispro or fast-acting aspart compared to standard insulin lispro and aspart using closed-loop insulin therapy: a systematic review and meta-analysis of randomized contr...
Published 2025-06-01“…BackgroundUltra-rapid-acting insulin (URAI) improves glycemic control by reducing variability; however, optimal strategies for its use, especially within hybrid closed-loop (HCL) insulin delivery systems, remain unclear. …”
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2824
CD20×CD3 bispecific antibody achieved significant efficacy in patients with large B-cell lymphoma relapsing after or refractory to CAR-T therapy: a systematic review and meta-analy...
Published 2025-08-01“…To validate these findings and determine the optimal sequencing of BsAbs and CAR-T therapy for R/R LBCL patients, prolonged follow-up periods and further prospective clinical trials are warranted.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024621005.…”
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2825
The Impact of Condensate Oil Content on Reservoir Performance in Retrograde Condensation: A Numerical Simulation Study
Published 2024-11-01“…Unlike previous studies, this research introduces an orthogonal experiment to establish a methodology for studying the dynamic sensitivity factors across different types of gas reservoirs and various development stages, systematically evaluating their contributions to condensate oil. …”
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Systematic analysis of tensile properties of the TiVNbMoCr high entropy alloys in terms of the physical parameters
Published 2024-11-01“…Optimizing elemental proportions is a potential pathway to enhance strength-ductility synergy of non-equimolar high entropy alloys (HEAs). …”
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2828
Long-term outcomes after revascularization surgery for adult moyamoya disease: Protocol for systematic review and meta-analysis.
Published 2025-01-01“…Herein, we designed the protocol for a systematic review and meta-analysis comparing the three different revascularization surgeries in adult MMD patients for more than 5 years long-term outcomes.…”
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Effect of calcium supplementation in reducing adverse obstetric and perinatal outcomes: an umbrella review of systematic reviews and meta-analyses
Published 2025-12-01“…Therefore, this study aims to provide a comprehensive umbrella review of the effect of calcium supplementation on adverse obstetrics and perinatal outcomes.Methods A systematic search was conducted in electronic databases (MEDLINE, Web of Science, SCOPUS, and Cochrane Library) from the first publication up to January 2024. …”
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2832
Stimulation of motor skills through game models in early childhood and elementary school students: systematic review in Indonesia
Published 2024-01-01“…According to the findings of this review, in the first group, traditional play-based children's learning is capable of optimizing kindergarten children's basic motor development, with a track record of implementing the concept/theoretical basis, activity stages, social systems, reaction principles, support systems, and impact models, and increasing students' basic skills for high motor skills. …”
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2833
Manual acupuncture enhanced therapeutic efficacy in vascular dementia rat model: systematic review and network meta-analysis
Published 2025-04-01“…Abstract Objective This study aimed to systematically evaluate the efficacy of electroacupuncture and manual acupuncture for treating vascular dementia and to determine the optimal acupuncture point combination scheme for efficacy. …”
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2834
Participant Compliance With Ecological Momentary Assessment in Movement Behavior Research Among Adolescents and Emerging Adults: Systematic Review
Published 2025-02-01“… BackgroundAdolescence through emerging adulthood represents a critical period associated with changes in lifestyle behaviors. …”
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Evaluating the efficacy and safety of immune checkpoint inhibitors in first and second-line treatments for recurrent and metastatic head and neck squamous cell carcinoma: a systema...
Published 2025-02-01“…IntroductionThis study systematically reviewed and conducted a network meta-analysis to assess the efficacy and safety of first-line and second-line immunotherapy treatments for recurrent and metastatic head and neck squamous cell carcinoma (R/M HNSCC). …”
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Análisis de la comunicación instruccional del profesorado de educación física desde una perspectiva socioconstructivista: Una revisión sistemática (Analysis of the instructional co...
Published 2024-06-01“…A systematic literature review was conducted in the WOS, Scopus and Dialnet databases in February 2024, following PRISMA guidelines. …”
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Assessment of efficiency of use of technologies of the distributed register in the conditions of digital economy
Published 2019-05-01“…In this regard, the key objective of the study is to study and systematize scientific approaches to assessing the effectiveness of using distributed registry technologies in the context of the development of the economy as a number, and to use the possibility of using them to find ways to optimize cryptobusiness and to develop the economy as a whole. …”
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Architectural Exploration and Performance Enhancement of the CVA6 RISC-V Core Using the Gem5 Simulation Framework
Published 2025-01-01“…To further enhance the architecture, we integrated machine learning algorithms to optimize performance and resource efficiency. This approach resulted in two distinct optimized models: a resource-efficient variant that reduced resource consumption by 12% with only a 0.2% decrease in RMS micro-benchmark IPC, and a performance-optimized model that improved performance by 29.5% while increasing resource usage by just 4.20%. …”
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High-Quality Marine Economic Development: Theoretical Sources, Constituent Elements and Practical Approaches of Marine New Quality Productive Forces
Published 2024-10-01“…The new quality productive forces theory provides a solid theoretical support and action guide for the high-quality development in various fields. …”
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eXplainable Artificial Intelligence in Process Engineering: Promises, Facts, and Current Limitations
Published 2024-11-01“…According to our research, XAI is becoming more and more positioned as a tool for decision support, with a focus on robustness and dependability in process optimization, maintenance, and quality assurance. …”
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