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Real-World Effectiveness of Triple Extrafine Fixed-Dose Combination with Beclomethasone/Formoterol/Glycopyrronium on Symptoms and Lung Function in COPD: A Systematic Review and Met...
Published 2025-05-01“…Although randomized controlled trials (RCTs) provide efficacy data, they may not fully represent real-world clinical practice, highlighting the value of real-world evidence (RWE).Methods: This study conducted a systematic review and meta-analysis of prospective observational multicenter studies to evaluate the real-world effectiveness of a triple extrafine FDC containing beclomethasone dipropionate (BDP), formoterol fumarate (FF), and glycopyrronium (G) in moderate-to-severe COPD patients. …”
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2342
Outcomes of dual mobility versus conventional total hip arthroplasty for patients with femoral neck fractures: a systematic review and meta-analysis including registry data
Published 2025-04-01“…Abstract Background This study compared the long-term efficacy and safety of dual mobility (DM) prostheses versus conventional total hip arthroplasty (c-THA) in femoral neck fracture (FNF) patients. FNFs have a high rate of post-surgical complications, with no consensus on the optimal prosthetic design. …”
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Discontinuation of immune checkpoint inhibitors for reasons other than disease progression and the impact on relapse and survival of advanced melanoma patients. A systematic review...
Published 2025-01-01“…BackgroundDespite durable responses achieved with Immune Checkpoint Inhibitors (ICIs), data about optimal duration of treatment, especially in the context of adverse events, remain scarce.ObjectiveTo systematically review the evidence concerning the impact of treatment discontinuation with ICIs for reasons other than progressive disease (PD) on relapse rates and survival of melanoma patients.MethodsA systematic literature search was conducted in three electronic databases until July 2024. …”
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Cervical cerclage for prevention of preterm birth and adverse perinatal outcome in twin pregnancies with short cervical length or cervical dilatation: A systematic review and meta-...
Published 2023-08-01“…<h4>Background</h4>The optimal approach to prevent preterm birth (PTB) in twins has not been fully established yet. …”
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Single Anastomosis Duodenoileostomy with Sleeve Gastrectomy Versus Sleeve Gastrectomy Alone: A Systematic Review and Meta-Analysis on Behalf of TROGSS—The Robotic Global Surgical S...
Published 2025-03-01“…<b>Objective:</b> This study aimed to assess and contrast the intraoperative and postoperative outcomes between patients who underwent SADI-S and those who underwent SG. <b>Methods:</b> A systematic review and meta-analysis were performed and registered under PROSPERO with the ID CRD42024532504. …”
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Treatment outcomes for patients with newly diagnosed or relapsed/refractory TP53-mutated mantle cell lymphoma: a systematic review and meta-analysisResearch in context
Published 2025-07-01“…Summary: Background: TP53 mutation is a critical predictor of early disease progression and poor prognosis in mantle cell lymphoma (MCL). …”
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Biochemical and biological evaluation of L-glutaminase from Aspergillus tamarii AUMC 10198 via solid-state fermentation
Published 2025-08-01“…Several fungal isolates were screened for extracellular L-glutaminase production, and the native isolated strain Aspergillus tamarii AUMC 10198 was identified as a potent high-yield producer. Process parameters influencing enzyme production were systematically optimized using a one-variable-at-a-time (OVAT) approach. …”
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The synergistic effects of circuit training and diet on weight loss, body fat percentage, and BMI in obese Indonesian females: a randomized controlled trial
Published 2025-04-01“…However, the effectiveness of smartwatch apps in improving cardiovascular performance still needs to be systematically evaluated. Objective: This study aims to assess the contribution of smartwatch apps in improving cardiovascular fitness training using a systematic review based on the PRISMA framework. …”
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Inverse freeform design in non-imaging optics: Hamilton’s theory of geometrical optics, optimal transport, and least-squares solvers
Published 2025-05-01“…We present a systematic derivation of three mathematical models of increasing complexity for optical design, based on Hamilton’s characteristic functions and conservation of luminous flux, and briefly explain the connection with the mathematical theory of optimal transport. …”
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Multi-Objective Optimization of Natural Lighting Design in Reading Areas of Higher Education Libraries
Published 2025-05-01“…Statistical analysis confirmed the significance of the improvements (<i>p</i> < 0.001). This study provides a systematic and reproducible method for optimizing natural lighting in educational spaces and offers practical guidance for energy-efficient and user-centered library design.…”
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Comparative Analysis and Systematic Review of Nanocomposite Resins in Restorative Dentistry: Durability and Antimicrobial Properties
Published 2025-04-01“…The risk biases of studies were assessed using the Cochrane Risk of Bias tool. Results: A total of 15 studies were included in the systematic review table out of an initial pool of 93 studies further filtered down via the screening process. …”
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Systematic Review of the Problematic Factors in the Evacuation of Cruise/Large Passenger Vessels and Existing Solutions
Published 2024-12-01“…<b>Methods:</b> Guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) approach, a comprehensive systematic literature search was conducted across academic databases, including Scopus, Science Direct, Google Scholar, and a limited number of academic journals that are heavily maritime-focused in their mission. …”
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Does Systematic Preliminar Colour Doppler Study Reduce Kidney Biopsy Complication Incidence?
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Systematic Review: Does Pre-Pubertal Spaying Reduce the Risk of Canine Mammary Tumours?
Published 2025-02-01“…However, a systematic review published more than 10 years ago questioned this. …”
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The impact of digital devices on the mental and physical health of primary school children: systematic review
Published 2024-11-01“…This study aims to evaluate the impact of digital devices on primary school children's mental and physical health through a systematic review. Using the PRISMA method, literature from PubMed, and Scopus was selected based on quality, relevance, and completeness of data. …”
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Systematic analysis of $$B_s \rightarrow SP$$ B s → S P decays in perturbative QCD approach
Published 2025-03-01“…Abstract Within the perturbative QCD (PQCD) framework, we present a systematic investigation of charmless $$B_s \rightarrow SP$$ B s → S P decays, where S and P denote scalar and pseudoscalar mesons, respectively. …”
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Systematic review of behavioural smoking cessation interventions for older smokers from deprived backgrounds
Published 2019-11-01“…There is currently limited evidence for how inequalities could be addressed through specific smoking cessation interventions (SCIs) for a lung cancer screening eligible population. This systematic review aims to identify the behavioural elements of SCIs used in older adults from low socioeconomic groups, and to examine their impact on smoking abstinence and psychosocial variables.Method Systematic searches of Medline, EMBASE, PsychInfo and CINAHL up to November 2018 were conducted. …”
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Effectiveness and impact of intravenous magnesium sulfate in spinal surgery systematic review and meta-analysis
Published 2025-06-01“…However, studies evaluating its effectiveness and safety in spinal surgery remain inconsistent, necessitating a comprehensive meta-analysis to assess its role.ObjectiveThis study aimed to perform a systematic meta-analysis to compare the safety and efficacy of magnesium sulfate against standard therapeutic options in spinal surgery.MethodsThe meta-analysis followed PRISMA guidelines. …”
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