The winding road to health: A systematic scoping review on the effect of geographical accessibility to health care on infectious diseases in low- and middle-income countries. by Fleur Hierink, Emelda A Okiro, Antoine Flahault, Nicolas Ray

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Increased Biological Effective Dose of Radiation Correlates with Prolonged Survival of Patients with Limited-Stage Small Cell Lung Cancer: A Systematic Review. by Lucheng Zhu, Shirong Zhang, Xiao Xu, Bing Wang, Kan Wu, Qinghua Deng, Bing Xia, Shenglin Ma

“…<h4>Materials and methods</h4>A quantitative analysis was performed through a systematic search of PubMed, Web of Science, and the Cochrane Library. …”
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Navigating the shots: Parental willingness to immunize their children with COVID-19 vaccines in Saudi Arabia explored through a systematic review and meta-analysis. by Moustafa Abdelaal Hegazi, Mohamed Hesham Sayed, Nadeem Shafique Butt, Turki Saad Alahmadi, Nadeem Alam Zubairi, Wesam Abdelaziz Elson

“…<h4>Conclusion</h4>This was the first SRMA from Saudi Arabia which emphasized the priority to focus on vaccine-related factors as main/key strategy of COVID-19 vaccines' drivers to convince parents in a logical way based on accurate cumulative and emerging scientific data about efficacy and safety of COVID-19 vaccines to optimize their uptake by children/adolescents. …”
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Comparing block characteristics of mixtures of short/intermediate- and long-acting local anesthetics for peripheral nerve block: a systematic review and meta-analysis by Cheng Lin, Ana Larissa Guerrero, Joshua Jesin, Rohin Tangri, Nasong Anthony Luginaah, Kamal Kumar, Christopher Hansebout

“…Introduction: Results from Randomized Controlled Trials (RCTs) on mixed Local Anesthetics (LA) are conflicting. We conducted a systematic review and meta-analysis on whether using mixed LA leads to faster onset of surgical block. …”
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Staged versus One-Time Complete Revascularization with Percutaneous Coronary Intervention in STEMI Patients with Multivessel Disease: A Systematic Review and Meta-Analysis. by Zhenwei Li, Yijiang Zhou, Qingqing Xu, Xiaomin Chen

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The regular effects of concurrent aerobic and resistance exercise on global cognition in healthy elderly populations: A systematic review with meta-analysis of randomized trials by Liang Ding, Lijie Lou, Mingyang Zhang, Xing Zhang

“…A comprehensive search was conducted across PubMed, Web of Science, EMBASE, Google Scholar, Cochrane Library, and CNKI up to July 2024. …”
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COVID-19 Vaccine Timing and Co-Administration with Influenza Vaccines in Canada: A Systematic Review with Comparative Insights from G7 Countries by Farah Al hashimi, Sherif Eneye Shuaib, Nicola Luigi Bragazzi, Shengyuan Chen, Jianhong Wu

“…Background/Objectives: Despite significant advancements in vaccine development and distribution, the optimal timing and integration of COVID-19 vaccination in Canada remain crucial to public health. …”
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Drug treatment options of high-risk biochemically recurrent prostate cancer based on efficacy and safety: a systematic review and Bayesian network analysis by Qian Wang, Qiyu Zhu, Haoyang Liu, Ke Huang, Xingming Zhang, Jinge Zhao, Hong Zeng, Jindong Dai, Yifu Shi, Hao Zeng, Pengfei Shen

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HIV susceptibility to second-generation integrase strand transfer inhibitors among people with multidrug resistance: a systematic review and meta-analysis protocol by Vincent Kamaël Mekel, Ezechiel Ngoufack Jagni Semengue, Aude Christelle Ka’e, Alex Durand Nka, Collins Ambe Chenwi, Hugues Germain Mimfe’e Mba, Naomi-Karell Etame, Aurelie Minelle Kengni Ngueko, Audrey Rachel Mundo Nayang, Bouba Yagai, Desiré Takou, Maria Mercedes Santoro, Nicaise Ndembi, Vittorio Colizzi, Carla Montesano, Carlo-Federico Perno, Francesca Ceccherini-Silberstein, Joseph Fokam

“…Objectives: The aim of this systematic review and meta-analysis will be to provide a summary of existing evidence on the HIV susceptibility to 2nd-Gen INSTI among people with multidrug resistance. …”
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Efficacy and safety of immune checkpoint inhibitors for brain metastases of non-small cell lung cancer: a systematic review and network meta-analysis by Bin Liu, Jie Chen, Mingqi Luo

“…BackgroundPrevious studies have demonstrated that immune checkpoint inhibitors (ICIs) significantly improve prognosis in lung cancer patients with brain metastases (BMs). This systematic review and network meta-analysis aims to evaluate the efficacy and safety of 10 ICIs recommended by the 2024 Chinese Society of Clinical Oncology guidelines for treating non-small cell lung cancer (NSCLC) without driver genes, focusing on NSCLC patients presenting with BMs.Materials and methodsA comprehensive literature search of PubMed, Embase, and the Cochrane Library was conducted through June 2024 to identify eligible controlled trials and head-to-head randomized controlled trials investigating 10 ICIs in NSCLC patients with BMs. …”
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Efficacy of daily versus alternate day oral iron supplementation for management of anaemia among general population: a systematic review and meta-analysis by Anupkumar D. Dhanvijay, Vipin Patidar, Jayvardhan Singh, Subodh Kumar, Shiv Kumar Mudgal, Seshadri Reddy Varikasuvu, Rajesh Kumar

“…Abstract Background Iron deficiency anemia (IDA) remains a prevalent global health issue. While oral iron therapy is the first-line treatment, the optimal dosing strategy—daily versus alternate-day—remains debated, especially for general population use. …”
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Effects of protein supplementation on muscle mass, muscle strength, and physical performance in older adults with physical inactivity: a systematic review and meta-analysis by Liying Zhang, Gongxiang Liu, Xiaoli Huang, Fuqian He

“…In accordance with the PRISMA guidelines, the outcome data were synthesized using meta-analysis via RevMan5.4 software or a narrative method. Results Eight data groups from six randomized controlled trials(RCTs) were included in the analysis, stratifying participants into three physical activity(PA) trajectories: sustained low PA (n= 1), transition to structured training from low PA (n= 4), and a shift from moderate to low PA (n= 3). …”
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1990–2041 Global burden of Burkitt lymphoma with 20 years forecast: A systematic analysis using the global burden disease of study of 2021 by Chengyun Dou, Yidan Sang, Hongbo Zhu, Chuangjie Cao

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Impact of bonding protocols and physical-mechanical properties of composite on durability and failure rate of fixed orthodontic retainers: a systematic review of laboratory studies by Maciej Jedliński, Marta Mazur, Claudia Salerno, Katarzyna Grocholewicz, Joanna Janiszewska-Olszowska

“…There is no direct relationship between the power of the polymerization lamp and composite conversion rate. To optimize fixed retention outcomes, composites should have a minimum islet width of 4–4.5 mm and a thickness of at least 1 mm. …”
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The Association Between COPD, Acute Exacerbations of COPD, and Survival in COPD, with Fat-Free Body Mass Index: A Systematic Review and Meta-Analysis by Hu C, Song B, Liu X, Sun L, Li M, He X

“…This meta-analysis evaluates the clinical significance of fat-free mass index (FFMI) in COPD prognosis.Methods: A systematic search of PubMed, Embase, Web of Science, Scopus, Ovid, and Cochrane Library (up to December 7, 2024) identified studies comparing FFMI among non-smokers, smokers, COPD patients, and those with acute exacerbations (AE) or mortality. …”
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Treatment Strategies and Prognostic Outcomes in Acute Limb Ischemia: A Systematic Review and Meta-Analysis Comparing Thrombolytic Therapy and Open Surgical Interventions by Mircea Cătălin Coșarcă, Nicolae Alexandru Lazăr, Suzana Vasilica Șincaru, Bogdan Corneliu Bandici, Eduard Costin Argatu, Cosmin Carașca, Ráduly Gergő, Dorin Constantin Dorobanțu, Cristian Trâmbițaș, Adrian Vasile Mureșan

“…<i>Conclusions</i>: While thrombolysis and surgical revascularization are effective, optimizing patient selection remains a key challenge. …”
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Nitrate–Nitrite–Nitric Oxide Pathway, Oxidative Stress, and Fertility Outcomes in Morbidly Obese Women Following Bariatric Surgery: A Systematic Review by Charalampos Voros, Despoina Mavrogianni, Aspasia Minaoglou, Alexios Karakasis, Anthi-Maria Papahliou, Vasileios Topalis, Antonia Varthaliti, Raphail Mantzioros, Panagiota Kondili, Menelaos Darlas, Regina Sotiropoulou, Diamantis Athanasiou, Dimitrios Loutradis, Georgios Daskalakis

“…This review investigates the molecular mechanisms by which bariatric surgery affects eNOS activity, the NO₃-NO₂-NO pathway, and oxidative stress reduction, with an emphasis on intracellular activities including mitochondrial biogenesis and NO production. A systematic review employing PRISMA criteria included articles published between 2000 and 2024 from PubMed, Scopus, and Embase that investigated NO₃-NO₂ pathways, oxidative stress markers, hormonal alterations, and reproductive outcomes in morbidly obese women following bariatric surgery. …”
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What proportion of people have long-term pain after total hip or knee replacement? An update of a systematic review and meta-analysis by Rachael Gooberman-Hill, Michael R Whitehouse, Hung-Yuan Cheng, Andrew David Beswick, Vikki Wylde, Wendy Bertram, Mohammad Ammar Siddiqui

“…One reviewer conducted data extraction, checked by a second reviewer. The risk of bias assessment was performed using Hoy’s checklist. …”
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Poor glycemic control and its predictors among people living with diabetes in low- and middle-income countries: a systematic review and meta-analysis by Abere Woretaw Azagew, Chilot Kassa Mekonnen, Mark Lambie, Thomas Shepherd, Opeyemi O. Babatunde

“…Stata version 17 was used for analysis. A random effect model was computed. Heterogeneity was assessed by the Cochrane Q test and I-squared (I2). …”
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Resistance or power training to enhance lower limb muscle morphology in ambulatory children with cerebral palsy? A focused systematic review with meta-analysis by Bo Liu, Jizhi You, Yunxiang Fan, Yunping Xia, Xiang Zhang, Yang Zhang

“…Eligible studies were randomized controlled trials assessing muscle fascicle length or proxy indicators of muscle fiber diameter following resistance or power training in children with CP. A random-effects meta-analysis was performed to calculate Cohen's d comparing strength training with regular physiotherapy.FindingsEight studies met the inclusion criteria and were systematically reviewed, with five included in the meta-analysis. …”
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