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2541
Preference for HIV testing among community residents in Yunnan Province, China: results from a discrete choice experiment
Published 2025-02-01“…Methods A discrete-choice experiment (DCE) was conducted in the communities of Yunnan Province, China. …”
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2542
Assessing learning, behaviour, and stress level in goats while testing a virtual fencing training protocol
Published 2025-02-01“…Virtually fenced goats stood significantly more vigilant than physically fenced ones. However, free-moving kids could have had an influence. The VF treatment had no significant effect on the FCM concentrations, which decreased significantly over time. …”
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2543
Exploring proteomic immunoprofiles: common neurological and immunological pathways in multiple sclerosis and type 1 diabetes mellitus
Published 2025-02-01“…Methods We conducted a proteomic analysis of PBMCs from patients with T1DM and relapsing remitting Multiple Sclerosis (herein forth MS) patients (n = 9 per condition), using a label-free quantitative proteomics approach. The patients were diagnosed following the American Diabetes Association (ADA) criteria for T1DM and McDonald criteria for MS respectively, and were aged over 18 years and more than 2 years from the onset respectively. …”
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2544
Venetoclax added to CLAG regimen might improve the outcome of patients with relapsed/refractory acute myeloid leukemia
Published 2025-02-01“…The endpoints of this study were to evaluate the rate of composite complete remission (CRc), measurable residual disease (MRD), event-free survival (EFS), overall survival (OS), and relapse between CLAG and CLAG + Ven groups. …”
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2545
Agreement Between Provider-Completed and Patient-Completed Preoperative Frailty Screening Using the Clinical Risk Analysis Index: Cross-Sectional Questionnaire Study
Published 2025-02-01“…MethodsOrthopedic physicians and physician assistants completed the RAI-C assessment on veterans aged 65 years and older undergoing elective total joint arthroplasty (eg, total hip or knee arthroplasty) and documented scores into the electronic health record during their preoperative clinic evaluation. …”
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2546
Review of the Effectiveness of the Existing Municipal Solid Waste Management Systems in Uganda. Case Study of Kabale Municipal Council, Kabale Municipality, Kabale District.
Published 2023“…Therefore, there is need for KMC to include all the people in working for the clean and health threat-free environment. The study also suggest that KMC should try to effect the existing systems plus adopting the modern techniques for the collection, transportation and disposing of solid waste in Kabale Municipality.…”
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2547
Access to Primary Education By Children With Physical Disabilities in Bwambara Sub-County Rukungiri District.
Published 2024“…The recommendations that came out of the study were that schools should give admission to CWPD at a free cost, and Schools should put up a special desk for CWD so that when they come for admission they don't wait for long hours. …”
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2548
Impact of Weed Infestation on Growth and Yield of Carrot Plants.
Published 2024“…The above results generally indicated that marketable carrot root tubers were high compared to unmarketable ones simply because the blocks that were weeded experienced a weed-free environment which made carrot crops grow well and give high yields. …”
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2549
Investigating Escherichia Coli (E. Coli) Contamination of Street Foods in Manjari Kabale District.
Published 2025“…The bags were placed in a box with ice packs to keep the sample cool (around 4°C) during transport. …”
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2550
Size distribution of extracellular vesicles in pretreatment ascites and plasma is correlated with primary treatment outcome in advanced high-grade serous carcinoma
Published 2025-02-01“…The correlations of the EV concentration and size distribution in ascites and plasma with treatment outcome, progression-free survival (PFS) and overall survival (OS) were analysed. …”
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2551
Effectiveness and safety of PD-1/L1 inhibitors as first-line therapy for patients with advanced or metastatic urothelial carcinoma who are ineligible for platinum-based chemotherap...
Published 2025-02-01“…Meta-analyses were performed to evaluate the frequencies of progression-free survival (PFS), overall survival (OS), complete response (CR), partial response (PR), stable disease (SD), progressive disease (PD), objective response rate (ORR), disease control rate (DCR), and grade ≥ 3 treatment-related adverse events (trAEs).ResultsTotally six studies were included for meta-analysis. …”
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2552
Photobiomodulation preconditioning for oral mucositis prevention and quality of life improvement in chemotherapy patients: a randomized clinical trial
Published 2025-02-01“…After two weeks of follow-up, 80% of patients in Group 2 and 86.7% in Group 3 remained free of oral mucositis. The remaining patients in both groups experienced only mild erythema. …”
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2553
Prognostic value of body adipose tissue parameters in cancer patients treated with immune checkpoint inhibitors
Published 2025-02-01“…The primary outcomes analyzed were hazard ratios (HRs) for overall survival (OS) and progression-free survival (PFS), as well as odds ratios (ORs) for disease control rate (DCR). …”
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2554
Physiological impact of Trichoderma viride agents on the quality and production of melon that is grown on soils continuously cropped to melon
Published 2025-02-01“…Trichoderma is a probiotic that can enhance the physiological traits of crops, encourage their growth, and raise their yield and quality. It is yet unknown, though, how Trichoderma influences the growth, physiological traits, and yield of melon grown on soils continuously cropped to melon. …”
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2555
Bergapten alleviates senescence of chondrocytes in osteoarthritis
Published 2025-02-01“…Immunofluorescence assay, RT-qPCR and Western blotting indicated that bergapten treatment induced significant increases in the expression of cell proliferation markers such as PCNA, CCND1 and CCNE1 (P<0.05), while decreases in the expression of apoptosis markers Caspase3 and BAX (P<0.05). …”
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2556
Anti-LAG-3 antibody LBL-007 plus anti-PD-1 antibody toripalimab in advanced nasopharyngeal carcinoma and other solid tumors: an open-label, multicenter, phase Ib/II trial
Published 2025-02-01“…In immunotherapy-naive NPC patients (n = 12), ORR was 33.3%, disease control rate (DCR) was 75%, and median progression-free survival (PFS) was 10.8 months (95% CI, 1.3 to not estimated). …”
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2557
Network Pharmacology and Experimental Validation of the Therapeutic Effect of Baji Capsule on LPS-Induced Osteoporosis
Published 2025-02-01“…The therapeutic effect of Baji capsule was evaluated by high-resolution micro-computed tomography (Micro-CT) and tissue section staining, serum inflammatory factor levels were assessed by ELISA, serum oxidative stress-related marker levels were determined by kits, and finally the mechanism was explored by network pharmacology and then verified by immunohistochemistry.Results: Micro-CT results showed that Baji capsule attenuated LPS-induced inflammatory bone loss.Baji capsule also reduced serum inflammatory factor levels and oxygen free radical production. Target screening by network pharmacology yielded a total of 236 active ingredients of Baji capsule, as well as 278 common targets after taking the intersection of Baji capsule active ingredient targets and osteoporosis disease-related targets.Conclusion: Baji capsule can treat osteoporosis by reducing inflammation and oxidative stress. …”
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2558
Barriers and facilitators to maternal healthcare in East Africa: a systematic review and qualitative synthesis of perspectives from women, their families, healthcare providers, and...
Published 2025-02-01“…Key facilitators identified included improved healthcare understanding and women's self-efficacy at the individual level, family support and positive social influences at the interpersonal level, high-quality services, reliable transportation, compassionate care, and health education at the health facility level, community initiatives, gender equality, and maternity waiting homes at the community level, as well as free maternity services and health extension programs at the policy level. …”
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2559
Community disaster exposure and first onset of depression: A panel analysis of nationally representative South African data, 2008-2017.
Published 2022-04-01“…We used panel data from the South African National Income Dynamics Study (SA-NIDS) from 2008-2017, consisting of 17,255 adult study participants who were depression free at baseline. Risk of first depression onset between individuals exposed and unexposed to community disaster was measured, accounting for multiple disaster exposure over time by fitting generalized estimating equation (GEE) regression models. …”
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2560
Enhanced antitumor activity of combined hepatic arterial infusion chemotherapy with Lenvatinib and PD-1 inhibitors in unresectable hepatocellular carcinoma: a meta-analysis
Published 2025-02-01“…Extract data on outcome measures such as overall survival (OS), progression-free survival (PFS), objective response rate (ORR), disease control rate (DCR), and adverse events (AEs). …”
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