Treatment Interruption and Regimen Change in Firstgeneration versus Second-generation Tyrosine Kinase Inhibitors used as First-line Therapy for Chronic Myeloid Leukemia by Melea A. Ward, Gang Fang, Kristy L. Richards, Christine M. Walko, Stephanie R. Earnshaw, Laura E. Happe, Susan J. Blalock

“…**Background:** Research has shown that treatment interruptions are associated with worse failure-free survival in chronic myeloid leukemia (CML); however they are commonly used in clinical trials to manage adverse events. …”
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Factors determining primary or delayed surgery for unilateral, non-metastatic Wilms tumor: a multicentric Egyptian study by Ahmed Elgendy, Amr Abdelhamid AbouZeid, Mohamed El-Debeiky, Shaimaa Abdelsattar Mohammad, Marwa Romeih, Ahmed Ebeed, Mohamed Abouheba, Mohammed Hamada Takrouney, Mahmoud Mostafa, Ahmed Khairi, Osama El-Naggar, Sameh Shehata

“…The 3-year overall and event-free survival for all patients were 91% and 89%, respectively. …”
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Estimation of antioxidant and hypolipidemic activities of extracts of Citrus x aurantium leaves in vitro by Loulia Al Hawat, Loai Alallan

“…The antioxidant activity of various concentrations of extracts was estimated by measurement of the ability of each extract to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical. Hypolipidemic activity of various concentrations of extracts was estimated by measurement of the bile acid binding capacity. …”
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Differentiated approach at the choice of chronic hepatitis C antiviral therapy mode (real clinical practice experience) by I. Yu. Pirogova, N. B. Kovaleva, E. P. Patlusov, E. S. Radchenko

“…As administration of interferon-free treatment modes for most of patients is limited due to financial considerations, application of IFN-based modes of treatment in clinical practice is still actual. …”
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Prevalence and correlates of facemask usage during the second wave of COVID-19 pandemic in Uganda. by Nelson Onira Alema, Christopher Okot, Emmanuel Olal, Eric Nzirakaindi Ikoona, Freddy Wathum Drinkwater Oyat, Steven Baguma, Denish Omoya Ochula, Patrick Odong Olwedo, Johnson Nyeko Oloya, Francis Pebalo Pebolo, Pamela Okot Atim, Godfrey Smart Okot, Ritah Nantale, Judith Aloyo, David Lagoro Kitara

“…We conducted a cross-sectional study on 587 adults across nine districts in northern Uganda, across 24 high-volume health facilities offering free COVID-9 vaccines. Respondents were selected from the health facilities using a single-stage systematic sampling method. …”
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Anti-constitutional activities and cover organisations of national-socialist movement in Klaipėda region in 1935-1937 by Mindaugas Valiukevičius

“…Around 1000 block and cell leaders remained free and carried on with their activities. Members of the forbidden SVG party and their supporters were restoring the national-socialist movement. …”
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Oncological outcomes following extreme oncoplastic breast conserving surgery (eOPBCS) for locally advanced breast cancer (LABC): A systematic review and meta-analysis by Megan Chua Wern Ee, Ashley Lee Shi Hui, Wong Hung Chew, Emmeline Elaine Cua-Delos Santos, Sean Li Siwei, Sng Ming Xian, Qin Xiang Ng, Serene Goh Si Ning

“…The primary outcomes were overall survival (OS), disease-free survival (DFS), and local recurrence rates (LRR). …”
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Long-term results of surgical treatment of a locally advanced rectal cancer using extrafascial principle of dissection by P. V. Tsarkov, I. A. Tulina, D. N. Fedorov, A. Yu. Kravchenko, O. Yu. Samofalova

“…The two-year cumulative relapse-free survival rate in group of standard operations (97,6%) appeared significantly higher, than in group of extrafascial resections: 92,4 and 88,2% respectively (р=0,02). …”
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Characteristics, clinical manifestations and management of leprosy in KwaZulu-Natal, South Africa: A 20-year retrospective study by J S Sons, Z N Mkhize, N C Dlova, C Aldous, P R Bhat, A V Chateau

“…These findings emphasise the urgent need for enhanced patient and healthcare worker education, particularly in primary healthcare settings, to improve adherence to treatment, advocate for prophylactic measures and prevent new cases. Achieving leprosy-free status in SA requires the collaboration of many role-players to address these challenges and improve healthcare practices. …”
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TAp63γ is the primary isoform of TP63 for tumor suppression but not development by Xinbin Chen, Wenqiang Sun, Xiangmudong Kong, Xin Ming, Yanhong Zhang, Wensheng Yan, Shakur Mohibi, Mingyi Chen, Keith Mitchell, Jin Zhang

“…Additionally, loss of p63γ shortens the lifespan of tumor-free mice potentially via increased cellular senescence. …”
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Shear bond strength of three different fixed retainers: Stainless steel wires versus fiber reinforced composite (An in Vitro study) by Anees Mahmood Mudhir

“…Methods: One‐hundred twenty extracted human upper premolar teeth (60 pairs) were divided into three groups(40 for each group) bonded with three different types of retainer wires (db Straight‐8strand flattened nickel free braided wire 0.028 x 0.008 inches UK, 3M 0.0175; multi‐stranded wire and Speed korean orthodontic fiber reinforced splint (2 mm x 200 mm ‐ FS‐2) which were bonded to the lingual surface of the teeth as fixed retainers by specific adhesives (Transbond LR, 3M). …”
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Validación psicométrica de la Escala de Premisas Histórico SocioCulturales de la Monogamia (EPHSCM) by Giovanna Escobar-Mota, Rozzana Sánchez-Aragón

“…La escala resulta ser una aportación metodológica en el área de la investigación, porque lo que la muestra mexicana cree, piensa y siente sobre la monogamia contribuye al entendimiento de cómo ciertas variables psicológicas influyen en parejas dentro de un contexto psico-socio-cultural particular como en esta muestra mexicana.…”
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How can Blood Flow Restriction Exercise be Utilised for the Management of Persistent Pain Following Complex Injuries in Military Personnel? A Narrative Review by Luke Gray, Peter Ladlow, Russell J Coppack, Robyn P Cassidy, Lynn Kelly, Sarah Lewis, Nick Caplan, Robert Barker-Davies, Alexander N Bennett, Luke Hughes

“…Conclusion Future research needs to examine the differences in pain modulation between persistent pain and pain-free populations with BFR application, supporting the investigation of mechanisms for BFR-induced hypoalgesia, the dose-response relationship between BFR-exercise and pain modulation, and the efficacy and effectiveness of BFR application in complex musculoskeletal and persistent pain populations.…”
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Design and Fabrication of a Car Sports Rims. by Nsimbe Laban

“…In this study, all the stresses that act on the car rim and other requirements that must be met by the car rim were determined using design equations and free body diagrams. The rim components capable of withstanding these stresses were sized and drafted using solid works 2020. …”
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Combined alverine citrate and simeticonein preparation in the treatment of irritable bowel syndrome by Ye. A. Poluektova, S. Yu. Kuchumova, V. T. Ivashkin

“…In IBS-D group of the patients, after 4-week course of meteospasmyl treatment stool frequency significantly decreased, consistency of feces became less loose. Intensity of abdominal pain by VAS data significantly decreased at the end of 4-week treatment course. …”
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Serum Zinc Levels in Women with Polycystic Ovarian Syndrome are Lower as Compared to Those without Polycystic Ovarian Syndrome: A Cohort Study by Swati Dhar, Reena Yadav, Akash Tomar

“…Background: Zinc is an essential micronutrient, a vital stabiliser and a cofactor in many enzymes such as superoxide dismutase and phospholipase C and also acts as an antioxidant by protecting the sulfhydryl groups of different proteins and enzymes against free radicals. It is unclear if serum zinc levels are correlated with polycystic ovary syndrome (PCOS) and its pathophysiology, although relation between diabetes and insulin resistance has been established. …”
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La costumbre al envenenamiento: El caso de los contaminantes atmosféricos de la ciudad de Guadalajara, México by Salvador Peniche-Camps, Mauro Cortez-Huerta

“…[Metodología]: Se delimitó el área de estudio, donde el Comité Estatal de Vigilancia Epidemiológica (CEVE) del estado de Jalisco, registró el mayor caso de incidencia de Infecciones Respiratorias Agudas (IRAs) en las primeras 26 semanas del 2018, las cuales perjudicaron principalmente, a niños y adultos mayores; se analizaron por medio del  modelo de regresión múltiple, mediante datos obtenidos del Sistema de Monitoreo Atmosférico de Jalisco (SIMAJ), los cuales cuentan con las concentraciones de los contaminantes, criterios que regula la Normatividad Mexicana (NOM). …”
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Predictive value of the perivascular fat attenuation index for MACE in young people suspected of CAD by Yani Yu, Dongkai Shan, Xi Wang, Zinuan Liu, Guanhua Dou, Junjie Yang, Yuqi Liu, Yundai Chen

“…K‒M survival analysis was conducted to assess the prognostic value of the perivascular FAI and improvement over traditional risk factor prediction methods. Results The event-free survival of patients in the high FAI group (FAI≥-75.2 HU) was significantly lower than that of patients in the low FAI group (FAI<-75.2 HU) at a median follow-up of 72.7 months (93.9% vs. 99.7%, P < 0.001). …”
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Growth, Yield and Quality of Maize under Ozone and Carbon Dioxide Interaction in North West India by Achchhelal Yadav, Arti Bhatia, Sudesh Yadav, Archana Singh, Ritu Tomer, Ramesh Harit, Vinod Kumar, Bhupinder Singh

“…To understand how the growth and nutritional quality of maize will be affected under elevated carbon dioxide (CO2) and tropospheric ozone (O3) interaction, a field experiment was conducted under free air O3 and CO2 enrichment rings (FAOCE) growing HQPM-1 and PMH-1 maize cultivars at New Delhi, India. …”
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Serum Carboxy-terminal Cross-linking Telopeptide Fragments of Type-2 Collagen Level in the General Population: A Pilot Study by Rajat Khanna, Divyam Jindal, Sudhir Singh

“…The sCTX-II estimation can be used to differentiate the cases of knee osteoarthritis from the normal population as it is independent of age, gender, and BMI. …”
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