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961
Refined photovoltaic parameters estimation via an improved Sinh Cosh Optimizer with trigonometric operators
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962
Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway
Published 2025-02-01“…By combining proteomic and transcriptomic datasets, we discovered PROS1 expression was significantly reduced in BLCA tissues and revealed the clinical relevance of PROS1 with BLCA. …”
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963
Filtration Performance and Fiber Shedding Behavior in Common Respirator and Face Mask Materials
Published 2023-01-01“…Thus, there is a need to evaluate the performance of the commonly used respirators and face masks. Two experimental systems were developed to investigate seven different mask materials, which have a fiber size range from 0.1 µm (100 nm) to 20 µm (20,000 nm). …”
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964
Causal role of plasma liposome in diabetic retinopathy: mendelian randomization (MR) study
Published 2025-02-01“…Methods Summary statistics for lipid levels and DR were obtained from the Genome-Wide Association Studies (GWAS) Catalog database and the FinnGen Consortium, respectively. We conducted a two-sample MR analysis, and statistical analysis were performed using the inverse variance weighted (IVW) with the addition of the MR-Egger, weighted median (WM), constrained maximum likelihood and model averaging (cML-MA) to test for causal associations between lipid levels and DR. …”
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965
Personalized treatment strategies for breast adenoid cystic carcinoma: A machine learning approach
Published 2025-02-01“…This study was designed to assess the efficacy of various treatment approaches for BACC and to create the first web-based tool to facilitate personalized treatment decisions. …”
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966
Addressing fabrication challenges in perovskite-silicon tandem solar cells with advanced simulation techniques
Published 2025-02-01“…Detailed process and device simulations reported in this work may pave the way in the fabrication of optimised perovskite/silicon tandem solar cell.…”
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967
CAV1 promotes epithelial-to-mesenchymal transition (EMT) and chronic renal allograft interstitial fibrosis by activating the ferroptosis pathway
Published 2025-02-01“…However, the mechanism by which ferroptosis contributes to the onset and progression of CAD remains unclear.MethodsThis study analyzed transcriptome data from renal transplant biopsy samples in the Gene Expression Omnibus (GEO), through clinical samples, animal models, and cell experiments, this study investigated the mechanism by which Caveolin-1 (CAV1) promotes CAD through the regulation of the ferroptosis pathway.ResultsThe elevated levels of CAV1 were found to positively correlate with CAD incidence. …”
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968
Geographical origin discrimination of Chenpi using machine learning and enhanced mid-level data fusion
Published 2025-02-01“…Four machine learning methods are employed to establish discrimination models based on GC and MIR data, with two mid-level data fusion strategies to combine the data. …”
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969
Immunogenic dying cells elicit potent anti-tumor T cell immunity against lung metastasis and tumorigenesis
Published 2025-01-01“…Methods ICD was induced by short exposure to lethal dose of chemotherapeutic drug doxorubicin (Dox), which initiated an irreversible ICD program in tumor cells. We immunized mice with ICD dying tumor cells in prevention, therapy in lung metastasis models, and Gprc5a-knockout (ko) model of lung tumorigenesis. …”
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970
Unmasking MRSA antibiotic resistance: the impact of environment, pollution, and healthcare quality—a nationwide exploration in China: a comprehensive analysis spanning 2014 to 2021...
Published 2025-02-01“…Environment and medical care data were obtained either from the National Bureau of Statistics (NBS) database or the National Ministry of Ecology and Environment (NMEE). …”
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971
Prevalence and risk factors of postpartum depression, general depressive symptoms, anxiety and stress (PODSAS) among mothers during their 4-week postnatal follow-up in five public...
Published 2020-06-01“…Participants will be mothers aged 18 years and above at 4 weeks postdelivery who are able to understand the English and Malay languages. …”
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972
Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts
Published 2025-02-01“…Moreover, treatment with S. deserti hydroethanolic extract relieved oxidative stress (reduction of MDA and H2O2) and the activity of antioxidant enzymes SOD, CAT and GPx. …”
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973
Dipropyl phthalate induces craniofacial chondrogenic defects in zebrafish embryos
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974
Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure
Published 2025-02-01“…Abstract Pluripotent stem cells provide a scalable approach to analyse molecular regulation of cell differentiation across developmental lineages. Here, we engineer barcoded induced pluripotent stem cells to generate an atlas of multilineage differentiation from pluripotency, encompassing an eight-day time course with modulation of WNT, BMP, and VEGF signalling pathways. …”
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975
Dose-volume parameter evaluation of a sub-fractionation workflow for adaptive radiotherapy of prostate cancer patients on a 1.5 T magnetic resonance imaging radiotherapy system
Published 2025-01-01“…Materials and methods:: The investigated workflow consisted of two sub-fractions where intrafraction drift correction steps were applied based on a daily reference plan. …”
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976
The impact of nationality status and place of residency on health-related social needs and quality of life among Palestinian Refugees in Jordan
Published 2025-02-01“…Introduction: Large number of Palestinian refugees reside in Jordan; most of whom enjoy Jordanian citizenship, and most of whom reside outside camps. …”
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977
Brivaracetam to Treat Partial Onset Seizures in Adults
Published 2023-01-01“…# Purpose of Review Seizures are a hyperexcitable, and hypersynchronous imbalance between excitatory and inhibitory factors (E/I imbalance) in neurotransmission, and epilepsy is the recurrent manifestation of seizures within a reasonable time frame and without being attributable to a reversible cause. Brivaracetam is a derivative of the antiepileptic agent, levetiracetam, that is used as adjuvant therapy for focal onset seizures. …”
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978
USP5 stabilizes YTHDF1 to control cancer immune surveillance through mTORC1-mediated phosphorylation
Published 2025-02-01“…A comprehensive understanding of the molecular mechanisms governing YTHDF1 protein stability is pivotal for enhancing clinical response rates and the effectiveness of immune checkpoint blockade in cancer patients. Here, we report that USP5 interacts with YTHDF1, stabilizing it by removing K11-linked polyubiquitination. …”
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979
CytoSorb hemoadsorption of apixaban during cardio-pulmonary bypass for heart transplantation
Published 2025-02-01“…Patients on the transplant waiting list often have multiple reasons for being anticoagulated. Intraoperative removal of apixaban using CytoSorb seems to be an interesting solution for patients on DOACs requiring an emergency CPB intervention. …”
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980
Factors determining primary or delayed surgery for unilateral, non-metastatic Wilms tumor: a multicentric Egyptian study
Published 2025-02-01“…A retrospective analysis was conducted on all patients with unilateral, non-metastatic WT treated at four major Egyptian institutions from January 2019 to January 2024. …”
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