Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction by Jingrun Lin, Xiaoqiu Zhu, Xuan Li, Yu Hong, Yaohui Liang, Siqi Chen, Chenzhuo Feng, Lin Cao

“…Hippocampal mRNA expression was analyzed using Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) enrichment. …”
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Investigation of gut microbiota in pediatric patients with peanut allergy in outpatient settings by Shouming Li, Jingyi Huang, Yunyun Xie, Di Wang, Xin Tan, Yufan Wang

“…Fecal samples were collected and genomic DNA was extracted for 16S rRNA gene sequencing to assess gut microbiota composition. …”
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Peligro sísmico en la zona metropolitana de Tuxtla Gutiérrez: dos casos de estudio by Roberto Moreno Ceballo, Jorge Antonio Paz Tenorio, Carlos Narcía López, Raúl González Herrera, Josué Alexis Clemente Quezada

“… En la Zona Metropolitana de Tuxtla Gutiérrez-conformada por los municipios de Tuxtla Gutiérrez, Chiapa de Corzo, Berriozábal, San Fernando y Suchiapa-, la interacción de la actividad humana con las características naturales ha originado escenarios peligrosos en los que se presentan diferentes niveles de vulnerabilidad ante eventos sísmicos. Las consecuencias de los sismos ocurridos en esta región sureste de la República Mexicana han cobrado vidas y generado daños importantes que han trascendido en los grupos con mayor grado de marginación de la población. …”
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First report of serological, molecular detection, and characterization of human parvovirus B19 infections among sickle cell anaemia patients in Khartoum State, Sudan by Khalid Salman, Sittna Hayder El Nagar, Abdel Rahim M. El Hussein, Mohammed A. El Hussein, Hadi M. Yassine, Hebah A. Al Khatib, Mashael Ali Al- Badr, Ibrahim Farah, Khalid A. Enan

“…The virus targets specific integration sites in the human genome, disrupting cellular division. However, the molecular mechanisms of infection remain poorly understood. …”
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Shaoyao Gancao decoction alleviates paclitaxel-induced cognitive impairment by activating PTEN/PI3K/AKT pathway to inhibit NETs formation by Xu Ying, Su Yue, Hu Yuwen, Li Xiang, Zhou Ziyan, Yuan Ningning, Ji Xiaowei, Jiang Ruoyu, Wang Wenzhu, Zhang Yafeng, Zhai Guojie, Cheng Xiaolan

“…Finally, Mendelian randomization was performed using genome-wide association analysis data of PTEN and cognitive disorders in OpenGWAS database. …”
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NALCN expression is down-regulated and associated with immune infiltration in gastric cancer by Xuewei Li, Xuewei Li, Na Wu, Chen Wang, Beibei Pei, Xiaoyan Ma, Jun Xie, Jun Xie, Wenhui Yang

“…Data obtained from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases were utilized to investigate the correlation between NALCN expression and immune cell infiltration in GC. …”
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Acesso à medicamentos oncológicos versus desabastecimento: desafios para o SUS by Evandro Abreu de Carvalho

“…Resultados: Foram selecionados 164 medicamentos oncológicos com interrupção produtiva entre 2014 a 2017, sendo 28,6% de forma definitiva. A maior motivação para interrupção tanto do tipo definitiva quanto temporária foi devido a razões comerciais. …”
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CONSULTA DE SEGUIMENTO DO DISPOSITIVO INTRAUTERINO (DIU) DE COBRE INSERIDO NO PERÍODO PÓS-PARTO E PÓS-ABORTAMENTO IMEDIATO by Rafaela Quintana Domingues, Camila Giugliani, Victor Matheus Santos da Silva

“…Para a validação e análise do material, foi utilizado o Índice de Validade de Conteúdo (IVC), sendo considerado válido um IVC > 0,75. Foram avaliados, ainda, os conhecimentos dos profissionais sobre o tema estudado por meio de pré e pós-teste. …”
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Validação transcultural da versão moçambicana da escala de autoeficácia em Educação Física inclusiva by Leonor Picardo, Maria João Campos, José Pedro Ferreira

“…Participaram 149 estudantes estagiários de EF, sendo 109 de género masculino (M=24,46 ± DP=3,16) e 40 do género feminino (M=21,38±DP=5,18) recrutados em cursos de EF nas universidades das zonas Sul, Centro e Norte de Moçambique. …”
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Impacto de altas temperaturas sobre la textura y agregación de un suelo del bosque de caldén: implicancias para la erosión eólica by María Sofía Larroulet, Fernando Avecilla, Laura Andrea de Oro, Adriana Noemí Correa, Rocío Noelia Comas

“…Estos agregados estarían formados por la recristalización de los compuestos de Fe y Al (microagregados densos), debido a la combustión del COT y reducción de la fracción más fina y reactiva del suelo. …”
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A REPRESENTAÇÃO SOCIAL DO VOTO COMO EXERCÍCIO DA CIDADANIA E DA DEMOCRACIA by Cinthya Amaral Santos, Humberto César Machado, João Felipe Fleury

“…Foi realizado um estudo bibliográfico sobre os conceitos de democracia, cidadania e a teoria da Representação Social, na primeira parte do estudo, sendo depois realizada a análise dos resultados gráficos, através do programa Iramuteq. …”
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Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure by Sophie Shen, Tessa Werner, Samuel W. Lukowski, Stacey Andersen, Yuliangzi Sun, Woo Jun Shim, Dalia Mizikovsky, Sakurako Kobayashi, Jennifer Outhwaite, Han Sheng Chiu, Xiaoli Chen, Gavin Chapman, Ella M. M. A. Martin, Di Xia, Duy Pham, Zezhuo Su, Daniel Kim, Pengyi Yang, Men Chee Tan, Enakshi Sinniah, Qiongyi Zhao, Sumedha Negi, Meredith A. Redd, Joseph E. Powell, Sally L. Dunwoodie, Patrick P. L. Tam, Mikael Bodén, Joshua W. K. Ho, Quan Nguyen, Nathan J. Palpant

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Lactate Dehydrogenase-A-Forming LDH5 Promotes Breast Cancer Progression by Fang T, Hu L, Chen T, Li F, Yang L, Liang B, Wang W, Zeng F

“…We aimed to explore the roles of LDHA and LDH5 isoenzyme activity in BC, which provides a new insight into LDHA for the treatment of BC.Methods: The expression of LDHA in BC and its relationship with clinicopathological features were obtained from various databases including The Cancer Genome Atlas (TCGA), Human Protein Atlas (HPA), Breast Cancer-Gene Expression Miner (bc-GenExMiner), TNMplot, UALCAN. …”
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A green forage diet enhances microbial diversity in buffalo rumen by Angela Salzano, Giovanna Bifulco, Alfio Calanni Macchio, Valentina Longobardi, Francesca Aragona, Giovan Maria Pacelli, Giuseppe Campanile

“…Rumen fluid samples were immediately collected at the slaughterhouse, and bacterial genomic DNA was extracted to perform metagenomic analyses. …”
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Potential pathogenic and protective genotypes and phenotypes of vitamin D binding protein in multiple sclerosis by Suhail Al-Shammri, Suhail Al-Shammri, Arpita Chattopadhyay, Abu Salim Mustafa

“…This study investigated frequencies of GC genotypes and phenotypes in Kuwaiti multiple sclerosis (MS) patients and healthy controls, and their associations with serum levels of 25 hydroxyvitamin D [25(OH)vitamin D] and VDBP.MethodsThe genomic DNA was isolated from blood samples of drug-naïve MS patients (N = 151) and controls (N = 127). …”
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Molecular characterization of ST15 carbapenem-resistant Klebsiella pneumoniae isolated in a single patient by Yongjin Hu, Rong Tang, Shanshan Jin, Jiahao Guan, Xiaoxiao Meng, Zengpeijie Dan, Ruilan Wang, Hong-Yu Ou, Jian Lu

“…Pulsed-field gel electrophoresis (PFGE) was used to investigate the homology relationship between the strains. The whole genome sequencing and phylogenetic analysis of 9 representative isolates was also performed. …”
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Development of a set of monosomic alien addition lines from Gossypium raimondii in Gossypium hirsutum toward breeding applications in cotton by Zhenzhen Xu, Xiaoxi Lu, Wenjie Ding, Wei Ji, Wuzhimu Ali, Heyang Wang, Shan Meng, Qi Guo, Peng Xu, Xianglong Chen, Liang Zhao, Huan Yu, Xinlian Shen

“…These MAALs will provide important genetic bridge materials for gene transfer from G. raimondii as well as for the study of Gossypium species genomes and their evolution. Conclusions A set of Gossypium hirsutum - Gossypium raimondii MAALs were developed and they showed abundant variation in morphological, agronomic, yield, and fiber quality traits, as well as in drought and salt resistance at seedling stage.…”
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Tumor mutational burden and survival on immune checkpoint inhibition in >8000 patients across 24 cancer types by Vivek Subbiah, Samuel J Klempner, Neeraj Agarwal, David P Carbone, Amit Mahipal, Shilpa Gupta, David Fabrizio, Jeffrey S Ross, Gerald Li, David R Gandara, Miles C Andrews, Jonathan W Riess, Ramez N Eskander, Ryon P Graf, Geoffrey R Oxnard, Sarah Sammons, Jeremy Snider, Lilia Bouzit, Cheryl Cho-Phan, Megan Price, Julia C F Quintanilha, Richard Sheng Poe Huang

“…Deidentified data from electronic health records from approximately 280 cancer treatment facilities were captured into a clinico-genomic database. This study used the TMB algorithm from the FDA-approved test supporting solid tumor CDx and composite mortality variable validated against the national death index: real-world overall survival (rwOS). …”
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PneumoniaCheck, a novel aerosol collection device, permits capture of airborne Mycobacterium tuberculosis and characterisation of the cough aeromicrobiome in people with tuberculos... by Tinaye L. Chiyaka, Georgina R. Nyawo, Charissa C. Naidoo, Suventha Moodley, Jose C. Clemente, Stephanus T. Malherbe, Robin M. Warren, David N. Ku, Leopoldo N. Segal, Grant Theron

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Direct engulfment of synapses by overactivated microglia due to cadmium exposure and the protective role of Nrf2 by Siyao Li, Mingdan You, Chengjie Chen, Jingqi Fu, Yuanyuan Xu, Jingbo Pi, Yi Wang

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