RETRACTED ARTICLE: NR3C2 affects the proliferation and invasiveness of colon cancer cells through the Wnt/β-Catenin signaling pathway by Ke Nie, Zhong-Jiang He, Ling-Jun Kong

“…Method mRNA (messenger RNA) data and clinical records pertaining to colon cancer were retrieved from The Cancer Genome Atlas (TCGA) database. The analysis of NR3C2 expression discrepancies between normal colon and tumor tissues was conducted using R software. …”
Get full text

Variabilidad climática y expresión de la fusariosis de la espiga de trigo en la región pampeana by R.C. MOSCHINI, M. I MARTINEZ

“…A partir de estos modelos se derivaron distribuciones de probabilidad de ocurrencia de períodos secos de al menos 7 días en lapsos de 15 días, para ambas fases. …”
Get full text

Identification of HOXA9 methylation as an epigenetic biomarker predicting prognosis and guiding treatment choice in acute myeloid leukemia by Fei Xie, Ting-juan Zhang, Xin-long Zhang, Zi-jun Xu, Liang Qiao, Yun Wang, Yang-jing Zhao, Jun Qian, Jing-dong Zhou

“…Methods We systematically first screened the prognostic value of HOXA cluster genes methylation in AML from The Cancer Genome Atlas (TCGA) datasets. Afterwards, the candidate prognosis-related gene HOXA9 were selected for clinical relevance analysis and were further validated in another independent cohort from our research center. …”
Get full text

Clinical efficacy of low‐dose Perampanel correlates with neurophysiological changes in familial adult myoclonus epilepsy 2 by Antonietta Coppola, Claudia Cuccurullo, Gianmaria Senerchia, Marica Rubino, Liana Veneziano, Francesco Brancati, Luigi Baratto, Valentina Virginia Iuzzolino, Leonilda Bilo, Pasquale Striano, Raffaele Dubbioso

Get full text

Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites by Yun Teng, Chao Luo, Xiaolan Qiu, Jingyao Mu, Mukesh K. Sriwastva, Qingbo Xu, Minmin Liu, Xin Hu, Fangyi Xu, Lifeng Zhang, Juw Won Park, Jae Yeon Hwang, Maiying Kong, Zhanxu Liu, Xiang Zhang, Raobo Xu, Jun Yan, Michael L. Merchant, Craig J. McClain, Huang-Ge Zhang

Get full text

Protocol of the Nurses’ Mental Health Study (NMHS): a nationwide hospital multicentre prospective cohort study by Jiaxin Yang, Chongmei Huang, Shuiyuan Xiao, Xuting Li, Meng Ning, Zengyu Chen, Yusheng Tian, Qiang Yu, Yamin Chen, Ya-Min Li

Get full text

Transcriptome Analysis of Effect of Cordyceps militaris Aqueous Extract in Human Gastric Cancer Cell BGC-823 on Different RCD Pathways by Mingqi CUI, Kaiwen YU, Yang SONG, Fangxu XU, Shenghou WANG, Ze WANG

“…Transcriptome analysis revealed significant differentially expressed genes (DEGs) and their Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment, resulting in the identification of 10 hub genes involved in the apoptosis, autophagy, necroptosis, and ferroptosis signaling pathways. …”
Get full text

Genetic trends and common BRCA1/2 pathogenic sequence variants in black African and Indian breast cancer patients presenting at Inkosi Albert Luthuli Central Hospital, KwaZulu-Nata... by M Makhetha, C Aldous, N Chabilal

“…We identified 30 pathogenic BRCA1/2 sequence variants, four large genomic rearrangements and 13 variants of unknown significance. …”
Get full text

Efecto de una intervención Act sobre la resistencia aeróbica y evitación experiencial en marchistas / Effect of an ACT Intervention on Aerobic Endurance and Experiential Avoidance... by María Clara Rodríguez-Salazar, Ángela Patricia Valero-Ballesteros

“…Los resultados señalan una mayor resistencia aeróbica en la prueba de los 3000 m en el postest del grupo experimental con respecto al grupo control, así como una mayor aceptación de los eventos internos negativos.   Abstract: The purpose of the present study was to identify the effect of an Acceptance and Commitment intervention Therapy (ACT) on aerobic endurance and experiential avoidance behavior of a group of walkers in Bogota. …”
Get full text

Examinando os fatores que afetam a preparação para o exame de certificação de engenharia industrial: um estudo rastreador by Aura Marie Novesteras, Niña Apusaga

“…Este estudo analisa as variáveis ​​que influenciam a preparação para o Exame de Certificação de Engenharia Industrial (CIE), incluindo a identificação das oportunidades e dificuldades que os candidatos enfrentam na preparação para o exame em termos de motivadores internos e externos e outros fatores. …”
Get full text

Targeted detection of endogenous LINE-1 proteins and ORF2p interactions by Mathias I. Nielsen, Justina C. Wolters, Omar G. Rosas Bringas, Hua Jiang, Luciano H. Di Stefano, Mehrnoosh Oghbaie, Samira Hozeifi, Mats J. Nitert, Alienke van Pijkeren, Marieke Smit, Lars ter Morsche, Apostolos Mourtzinos, Vikram Deshpande, Martin S. Taylor, Brian T. Chait, John LaCava

“…Instead, assays for ORF2p have been limited to ectopic L1 ORF over-expression contexts and to indirect detection of endogenous ORF2p enzymatic activity, such as by the sequencing of de novo genomic insertions. Immunoassays for endogenous ORF2p have been problematic, producing apparent false positives due to cross-reactivities, and shotgun MS has not yielded reliable evidence of ORF2p peptides in biological samples. …”
Get full text

Huerto urbano Adelfas (Madrid, 24 de enero de 2021) by Claudia Antón Biezma

“…Además, se fomentan las relaciones personales entre los que participan allí, los colegios pueden visitarlos y se sorprenden de lo que ven allí. Se cambia la geografía de las ciudades con su instalación y aprovechamiento de zonas sin utilizar, además de ser pequeños pulmones verdes que nos ayudan con la contaminación que tenemos. …”
Get full text

Streptococcus agalactiae: HASTA AHORA EL ÚNICO Streptococcus PATÓGENO DE TILAPIAS CULTIVADAS EN COLOMBIA by AP Jiménez, AL Rey, LG Penagos, MF Ariza, J Figueroa, CA Iregui

“…Los resultados del presente estudio demostraron que hasta la fecha en el país únicamente se ha identiÀcado la especie S. agalactiae causando infección o enfermedad en tilapias. No tenemos evidencia de que otros Streptococcus reportados internacionalmente como S. iniae y otros Gram positivos causen estreptococosis en Colombia.La tilapia parece ser el principal reservorio del S. agalactiae en el país, y el riesgo zoonótico, aunque existe, es mínimo si se toman las medidas apropia-das de bioseguridad.…”
Get full text

Huerto urbano Adelfas (Madrid, 24 de enero de 2021) by Claudia Antón Biezma

“…Además, se fomentan las relaciones personales entre los que participan allí, los colegios pueden visitarlos y se sorprenden de lo que ven allí. Se cambia la geografía de las ciudades con su instalación y aprovechamiento de zonas sin utilizar, además de ser pequeños pulmones verdes que nos ayudan con la contaminación que tenemos. …”
Get full text

LITERACIA CIENTÍFICA: UM OLHAR SOBRE AS SUAS DIFERENTES INTERPRETAÇÕES by MARCELO COPPI, ISABEL FIALHO, MARÍLIA CID

“…RESUMO: O estudo teve por objetivo realizar uma abordagem crítica e histórica a respeito do conceito de literacia científica, da definição das palavras que compõem o termo, das suas traduções e da existência de instrumentos desenvolvidos para avaliá-la, mediante uma revisão narrativa da literatura. …”
Get full text

Biology-Informed inverse problems for insect pests detection using pheromone sensors by Malou, Thibault, Parisey, Nicolas, Adamczyk-Chauvat, Katarzyna, Vergu, Elisabeta, Laroche, Béatrice, Calatayud, Paul-André, Lucas, Philippe, Labarthe, Simon

Get full text

The dual anti-inflammatory and anticoagulant effects of Jianpi Huashi Tongluo prescription on Rheumatoid Arthritis through inhibiting the activation of the PI3K/AKT signaling pathw... by Fanfan Wang, Fanfan Wang, Jian Liu

“…Furthermore, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) results suggested that the pharmacodynamic mechanism of XFC may be closely related to the regulation of the PI3K/AKT signaling pathway. …”
Get full text

Awake brain MRSI reveals anesthetic sensitivity and regional aging effects on [13C]bicarbonate metabolism in mice by Maiko Ono, Rena Kono, Kosei Hirata, Kosei Hirata, Keita Saito, Motonao Nakao, Yoichi Takakusagi, Rikita Araki, Akira Sumiyoshi, Yuhei Takado

Get full text

Different lysine-to-methionine ratios in a low-protein diet affect the microbiome and metabolome, influencing the jejunal barrier function in Tibetan sheep by Fengshuo Zhang, Zhenling Wu, Yu Zhang, Quyangangmao Su, Kaina Zhu, Xuan Chen, Shengzhen Hou, Linsheng Gui

“…The functional analysis based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) annotations indicated that these metabolites were mainly involved in pantothenate and CoA biosynthesis, ferroptosis, and the tricarboxylic acid cycle. …”
Get full text

Targeting HVEM-GPT2 axis: a novel approach to T cell activation and metabolic reprogramming in non-small cell lung cancer therapy by Yuanshan Yao, Chunji Chen, Bin Li, Wen Gao

“…Methods The lung cancer datasets for this study were directly downloaded from The Cancer Genome Atlas (TCGA). Single-cell data were sourced from the Tumor Immune Single-cell Hub (TISCH). …”
Get full text