Direct and Indirect Methods for Studying Human Gut Microbiota by V. T. Ivashkin, O. S. Medvedev, E. A. Poluektova, A. V. Kudryavtseva, I. R. Bakhtogarimov, A. E. Karchevskaya

“…Integration of the data obtained by gut microbiota studies at the genome, transcriptome and metabolome levels would allow a comprehensive analysis of microbial community function and its interaction with the human organism. …”
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Improving drug repositioning with negative data labeling using large language models by Milan Picard, Mickael Leclercq, Antoine Bodein, Marie Pier Scott-Boyer, Olivier Perin, Arnaud Droit

“…A detailed review of the top 30 revealed 9 promising drugs targeting various mechanisms such as genomic instability, p53 regulation, or TMPRSS2-ERG fusion. …”
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An initial exploration of core collection construction and DNA fingerprinting in Elymus sibiricus L. using SNP markers by Xinrui Li, Xinrui Li, Xinrui Li, Daping Song, Mingfeng Li, Daxu Li, Minghong You, Yan Peng, Jiajun Yan, Shiqie Bai

“…Additionally, we identified 290 SNP loci from among the high-quality SNP loci generated by whole-genome sequencing of the 90 E. sibiricus samples as candidate markers. …”
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Mulheres nas ciências, engenharia e tecnologia: o que as publicações científicas apontam? by Marina Gomes Murta Moreno, Cíntia Maria Gomes Murta

“…Os resultados mostram que o período mais produtivo é recente, sendo, os Estados Unidos, o país com o maior quantitativo de publicações e Women and science careers: leaky pipeline or gender filter?…”
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Memórias sobreviventes à “Solução Final”: reflexões inspiradas em “A mulher de pés descalços” de Scholastique Mukasonga by Anita Maria Pequeno Soares

“… Compreender tragédias, como a que aconteceu em Ruanda em 1994, requer um olhar atento ao que o Ocidente fez com a África em termos práticos como também teóricos. Nesse ano, quase um milhão de ruandeses foram brutalmente assassinados nas lutas fratricidas entre os tutsis e os hutus. …”
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Dicoumarol sensitizes hepatocellular carcinoma cells to ferroptosis induced by imidazole ketone erastin by Ziwei Yang, Ziwei Yang, Tixin Han, Ruibin Yang, Ruibin Yang, Yinuo Zhang, Yinuo Zhang, Yifei Qin, Yifei Qin, Yifei Qin, Jialu Hou, Jialu Hou, Fei Huo, Fei Huo, Zhuan Feng, Zhuan Feng, Yaxin Ding, Yaxin Ding, Jiali Yang, Jiali Yang, Gang Zhou, Gang Zhou, Shijie Wang, Shijie Wang, Xiaohang Xie, Xiaohang Xie, Peng Lin, Peng Lin, Zhi-Nan Chen, Zhi-Nan Chen, Jiao Wu, Jiao Wu

“…The intrinsic factors determining sensitivity to IKE-induced ferroptosis remain to be explored to improve its efficacy.MethodsBulk RNA-sequencing data from hepatocellular carcinoma (HCC) and normal liver tissues were collected from The Cancer Genome Atlas (TCGA) and the Genotype-Tissue Expression (GTEx) databases. …”
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RETRACTED ARTICLE: Single-cell omics and machine learning integration to develop a polyamine metabolism-based risk score model in breast cancer patients by Xiliang Zhang, Hanjie Guo, Xiaolong Li, Wei Tao, Xiaoqing Ma, Yuxing Zhang, Weidong Xiao

“…Data from The Cancer Genome Atlas, Gene Expression Omnibus, and Genotype-Tissue Expression identified 286 differentially expressed genes linked to polyamine pathways in breast cancer. …”
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Standardization and validation of a novel reverse transcriptase polymerase chain reaction method for detecting virulent strains of the infectious bursal disease virus by Vladimir Longa-Bobadilla, Phillip Ormeño-Vásquez, Manuel Criollo-Orozco, Luis Tataje-Lavanda, Katherine Huamán-Gutierrez, Ángela Montalván, Mirko Zimic, Manolo Fernández-Sanchez, Manolo Fernández-Díaz

“…For many years, the development of molecular techniques for either diagnostic purposes or surveillance of the appearance of new pathogenic strains has mainly focused on targeting the VP2 genomic region. However, due to the constant necessity for the discrimination between already prevalent vaccine strains and new pathogenic strains of this virus, it becomes imperative to have an immediate molecular method targeting a consensus sequence to achieve this task using field samples to reduce costs. …”
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Uma sistematização da formação de monitores de ensino fundamentada na educação médica baseada em competências by Livia Souza Pugliese, Adriana Pedrosa Moura

“…OBJETIVOS: Relatar a experiência de planejamento e elaboração de uma sistematização de formação de monitores acadêmicos tendo como referencial os princípios da educação médica baseada em competências. …”
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Overcoming the Silencing of Doxycycline-Inducible Promoters in hiPSC-derived Cardiomyocytes [version 1; peer review: 1 approved, 2 approved with reservations] by Michelle Guichardaz, Elisa Balmas, Alessandro Bertero, Sveva Bottini

“…The doxycycline (dox)-inducible OPTi-OX system, which integrates the Tet-On 3G transactivator and dox-responsive transgene at the hROSA26 and AAVS1 genomic safe harbors (GSHs), respectively, offers a promising solution. …”
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Revealing the core suppression effects of various Di (2-ethylhexyl) phthalate exposure on early meiosis progression in postnatal male mice via single-cell RNA sequencing by Baoquan Han, Lei Hua, Shuai Yu, Wei Ge, Cong Huang, Yu Tian, Chunxiao Li, Jiamao Yan, Tian Qiao, Jiachen Guo, Dongliang Lu, Bin Wang, Diya Cai, Yunqi Zhang, Shaolin Liang, Jianjuan Zhao, Qi Hou, Wei Shen, Zhongyi Sun

“…The transcriptomic changes in testicular cells of postnatal male rodents following DEHP exposure were meticulously analyzed using 10X Genomics single-cell RNA sequencing in this study. …”
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O impacto da expansão da política federal de educação na adequação da formação docente no Brasil by Roberta dos Reis Neuhold, Márcio Rogério Olivato Pozzer

“…À época, diagnosticava-se o agravamento da escassez de professores, tanto em termos quantitativos (traduzido na falta de professores) quanto qualitativos (com muitos profissionais em sala de aula que não possuíam a graduação específica no componente curricular que lecionavam). …”
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Conhecimento de profissionais de saúde sobre síndrome da apneia obstrutiva do sono em hospital particular do Recife by Jorge Luís Cassiano Alves Veras, Frederico Lins e Silva Pires Neto, Patrícia Gomes de Matos Bezerra, Suélem Barros de Lorena

“…RESULTADOS: Um total de 82 profissionais participaram do estudo, sendo 22 enfermeiros, 31 fisioterapeutas, 5 fonoaudiólogos e 24 médicos. …”
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Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach by Genbao Zhu, Genbao Zhu, Genbao Zhu, Zhiming Jiang, Niuping Zhu, Niuping Zhu, Donghui Wang, Donghui Wang, Tianpeng Guo, Tianpeng Guo, Yiqing Meng, Yiqing Meng, Yi Zhu, Yi Zhu, Kemeng Tan, Mengxue Hu, Heng Tang, Xuannian Wang, Xuannian Wang

“…Next, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed to elucidate associated biological functions and signaling pathways. …”
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Produção científica dos discentes do curso de medicina de uma instituição privada: um estudo transversal by Samantha Almeida Máximo, Alice Santos Bastos, Alexandry Libiny Souza Nunes, Regiane Patrícia Oliveira Miranda, Cristina Aires Brasil, Amanda Queiroz Lemos

“…Todos participaram de eventos e/ou congressos, 27 apresentaram trabalhos científicos no último ano e 26 relataram participar de grupos de pesquisa vinculados ao CNPq. …”
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Taxonomic refinement of Bacillus thuringiensis by Nagham Shiekh Suliman, Reza Talaei-Hassanloui, Hamid Abachi, Sadegh Zarei, Ebrahim Osdaghi

“…By October 2023, whole genome sequences (WGS) of 885 bacterial strains were labeled as B. thuringiensis in the NCBI GenBank database. …”
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Transcriptomic reprogramming and epigenetic regulation underlying pollination-dependent and auxin-induced fruit set in tomato by Xiaohan Li, Xiaohan Li, Xiaohan Li, Bing He, Anis Djari, Pierre Frasse, Elie Maza, Farid Regad, Julien Pirrello, Guojian Hu, Guojian Hu, Guojian Hu, Guojian Hu, Mondher Bouzayen

“…Notably, this developmental process can also proceed in the absence of flower fertilization, although it remains unclear whether pollination-dependent and pollination-independent fruit sets undergo similar transcriptomic reprogramming. Genome-wide transcriptomic profiling of the flower-to-fruit transition, either pollination-induced or triggered by auxin treatment, shows that both types of triggers modulate the expression of a common large set of genes primarily expressed in maternal tissues. …”
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Práticas colaborativas e a atuação dos bibliotecários multiplicadores da competência em informação by Ana Maria Miranda, Adriana Rosecler Alcará

“…Método: Pesquisa de campo, descritiva e com abordagem qualitativa, tendo como técnica de coleta de dados o grupo de foco, que foi realizado com um grupo de bibliotecárias de diferentes tipos de bibliotecas. …”
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Activin levels correlate with lymphocytic infiltration in epithelial ovarian cancer by Elizabeth T. Evans, Emily F. Page, Alex Seok Choi, Zainab Shonibare, Andrea G. Kahn, Rebecca C. Arend, Karthikeyan Mythreye

“…Immune gene expression profile was further explored within the TCGA‐OV cohort derived from The Cancer Genome Atlas (TCGA). Immunohistochemical analysis was performed to evaluate activin A and T‐cell markers CD8 and FoxP3 at the protein level. …”
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Representations and imaginaries of cities in the opening sequences of three U.S. TV series: The Sopranos, Weeds and House of Cards by Marta Gallardo, David García-Reyes

“…Las tres secuencias de apertura conforman y representan los estereotipos del imaginario colectivo que tenemos del paisaje urbano de la costa este y oeste del país.   …”
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