Spatial Vibration Characteristics and Damage Identification of Toppling Dangerous Rock Mass by Chen ZHAO, Mowen XIE, Yan DU, Zhengjun HUANG, Zheng HE, Guang LU

“…This study aims to develop a high sensitivity index that can reflect the spatial three-dimensional damage evolution process of the dangerous rock mass. It investigates the spatial vibration characteristics of the damage evolution process, proposing a particle trajectory time-domain dynamics index with heightened sensitivity to the damage of the dangerous rock mass structural plane in various directions of damage evolution.Methods Dangerous rock mass is regarded as a three-dimensional entity. …”
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Rapid cochlear gene therapy in adult deaf mice: Vglut3 rescue via AAV8 achieves day-1 hearing restoration by Ting Zhang, Rongqun Zhai, Mengli Liu, Hongen Xu, Liang Wang, Wenxue Tang, Bei Chen, Xingle Zhao

“…This study provides critical insights into the dynamic processes underlying cochlear gene therapy and challenges the conventional paradigm that 1–2 weeks are required for functional recovery.…”
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CRISPR/Cas9-based iterative multi-copy integration for improved metabolite yields in Saccharomyces cerevisiae by Ximei Chen, Chenyang Li, Xin Qiu, Ming Chen, Yongping Xu, Shuying Li, Qian Li, Liang Wang

“…This system combines the mixture of Cas9-sgRNA expression vectors with a split-marker strategy for efficient donor DNA assembly in vivo and enables rapid, iterative screening through growth-related phenotypes. …”
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Development of nucleic acid-based vaccines against dengue and other mosquito-borne flaviviruses: the past, present, and future by Muhammad Bashir Bello, Ahlam Alsaadi, Asif Naeem, Sarah A. Almahboub, Mohammad Bosaeed, Mohammad Bosaeed, Safia S. Aljedani

“…The global prevalence of these viruses is largely driven by extensive international travels and ecological disruptions that create favorable conditions for the breeding of Aedes and Culex species, the mosquito vectors responsible for the spread of these pathogens. …”
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EVOLUTION OF THE PHENOMENON OF CITIZENSHIP IN THE CONTEXT OF HISTORICAL DEVELOPMENT OF THE WESTERN EUROPE by L. Y. Maximova

“…It is possible that the Modern period is the beginning of the third cycle, which will continue its development in accordance with the aforementioned vectors.…”
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Conceptual design and thermodynamic investigation of novel energy and fuel generation systems from municipal waste coupled with carbon capture and storage by Qurrotin Ayunina Maulida Okta Arifianti, Stavros Michailos, Maria Fernanda Rojas Michaga, Karim Rabea, Kevin J Hughes, Lin Ma, Derek Ingham, Mohamed Pourkashanian

“…Traditional waste-to-energy processes rely on incineration, but more efficient and sustainable solutions are needed. …”
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Advancing West Nile virus monitoring through whole genome sequencing: Insights from a One Health genomic surveillance study in Romagna (Italy) by Martina Brandolini, Alessandra Mistral De Pascali, Irene Zaghi, Giorgio Dirani, Silvia Zannoli, Ludovica Ingletto, Antonio Lavazza, Davide Lelli, Michele Dottori, Mattia Calzolari, Massimiliano Guerra, Carlo Biagetti, Francesco Cristini, Paolo Bassi, Rino Biguzzi, Monica Cricca, Alessandra Scagliarini, Vittorio Sambri

“…Whole genome sequencing (WGS) analyses confirmed the circulation of WNV lineage 2 showing high nucleotide and amino acid identity of 99.82 % and 99.92 % respectively among viral sequences from human patients, vectors and birds. All the sequences clustered with other Italian strains in the Central and Southern European clade with robust bootstrap support and BLASTn identity exceeding 99.7 %. …”
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Anaerobic Digestion of Cattle Manure Contaminated with an Antibiotic Mixture: A Nature-Based Solution for Environmental Management by Giulia Massini, Anna Barra Caracciolo, Jasmin Rauseo, Francesca Spataro, Giulia Scordo, Luisa Patrolecco, Gian Luigi Garbini, Andrea Visca, Paola Grenni, Ludovica Rolando, Valentina Mazzurco Miritana

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Quantitative Methods of Selecting a Tool for Project Management in the Financial Sector by D. A. Vlasov, P. A. Karasev, A. V. Sinchukov

“…Within the framework of this article, the features of the choice of a project management tool in the financial sector based on the use of quantitative methods that make the decision-making process significantly more meaningful and effective are disclosed.The aim of the study is to develop elements of a methodology for quantitative analysis of alternative tools, including recommendations on the choice of alternatives and criteria for their analysis, as well as the complex use of various methods to justify the final choice of an instrument.The research materials and methods reflected in the methodology of quantitative analysis of alternative project management tools in the financial sphere, and implemented in the course of the research, are based on supplementing the results obtained through the use of the classical basic level method – the method of geometric averages by methods of advanced level decision theory – the method of eigenvalues and vectors, as well as the ideal point method. …”
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Characterization of FosA13, a novel fosfomycin glutathione transferase identified in a Morganella morganii isolate from poultry by Runzhi Zhang, Runzhi Zhang, Yan Yu, Yan Yu, Lulu Huang, Susu Chen, Ruxi Hu, Xiuxiu Wang, Dawei Huang, Chunhan Song, Junwan Lu, Qiyu Bao, Qiyu Bao, Qiyu Bao, Qiyu Bao, Yunliang Hu, Pengfei Jiang, Wei Pan

“…The FosA13 protein encoded by the novel resistance gene fosA13 was expressed with the vector pCold I, and its enzyme kinetics parameters were characterized. …”
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The future of critical care: AI-powered mortality prediction for acute variceal gastrointestinal bleeding and acute non-variceal gastrointestinal bleeding patients by Zhou Liu, Guijun Jiang, Liang Zhang, Palpasa Shrestha, Yugang Hu, Yi Zhu, Guang Li, Yuanguo Xiong, Liying Zhan

“…Meanwhile, SHAP waterfall outputs the model prediction process with true positive and negative patients. …”
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Optimal 2D Placement of Virtual Objects in Physical Space for Augmented Reality Applications by M. V. Alpatova, Yu. V. Rudyak

“…The first axis was horizontal, the second was directed forward from the user (this is the depth vector, or frontal measurement). The 1D-placement algorithm for the generated row provided optimal positioning the objects along X-axis based on the calculated comfort coefficient К. …”
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The HRAS-binding C2 domain of PLCη2 suppresses tumor‐like synoviocytes and experimental arthritis in rheumatoid arthritis by Hyun Min Jeon, Hae Sook Noh, Min-Gyu Jeon, Jin-Ho Park, Young-Sun Lee, Gyunghwa Seo, Yun-Hong Cheon, Mingyo Kim, Myung-Kwan Han, Jae-Yong Park, Sang-Il Lee

“…Here we performed functional C2 domainomics with 144 C2 domain-containing viral vectors and identified the C2 domain of PLCη2 as a key regulator of RA FLSs. …”
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Inhibition of HPV18 E6/E7 Protein-Expressing HeLa Cell Proliferation Using Optimized De Novo CRISPR/Cas9 Constructs Delivered by the LL-37 Peptide by Niloofar Khairkhah1, Azam Bolhassani2, 3*, Reza Najafipour1, 4, Ali Namvar3, Alireza Milani2, Elnaz Agi3, Ali Anvar3, Mohammad Sadeqh Khosravy5

“…The sgRNA sequences were cloned into CRISPR/Cas9 expression vectors. HPV18-positive HeLa cells, were transfected in vitro with the recombinant vectors to assess gene editing efficiency. …”
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Hybrids versus parental species: insights from wing phenotype similarities and differences in triatomine insects by Álvaro Lara, María Laura Hernández, María Laura Hernández, César A. Yumiseva, Mario J. Grijalva, Mario J. Grijalva, Anita G. Villacís

“…IntroductionThe genus Panstrongylus is one of the most important within the subfamily Triatominae, which includes vectors of Trypanosoma cruzi, the etiological agent of Chagas disease (CD). …”
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CONCEPTUAL FEATURES OF OCCLUSAL BALANCE IN THE DEVELOPMENT AND PATHOLOGY OF LOCALIZED AND GENERALIZED DISEASES OF PARODONTAL TISSUES IN PATIENTS WITH PARTIAL TOOTH LOSS DURING ORTH... by Yu.O. Kinash, L.V. Kinash

“…Therefore, the force vectors on the tooth axis continuously change in the articulation cycle, which helps to change the force of the occlusal interaction of the dentitions and the direction on the periodontium itself and the bone tissue of the jaws. …”
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Generation and characterization of induced pluripotent stem cells of small apes by Yusuke Hamazaki, Hiroto Akuta, Hikaru Suzuki, Hideyuki Tanabe, Kenji Ichiyanagi, Takuya Imamura, Masanori Imamura, Masanori Imamura, Masanori Imamura

“…Using Sendai virus-based stealth RNA vectors, we generated 31 reprogrammed cell lines, five of which were developed into transgene-free induced pluripotent stem cells. …”
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A new yeast strain for valorisation of vinasse, a rum distillery waste product by Brigita Simonaviciene, Ayokunle Araoyinbo, Juwayria Ali, Jamie McGowan, David A. Fitzpatrick, Gary Jones, Celia Ferreira, Andrew R. Pitt, Corinne M. Spickett, Vincent Postis, Carine de Marcos Lousa

“…Abstract Background Waste valorisation refers to processes of reusing or recycling waste materials to create valuable products. …”
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Construction of a sugar and acid content estimation model for Miliang-1 kiwifruit during storage by LIU Li, YANG Tianyi, DONG Congying, SHI Caiyun, SI Peng, WEI Zhifeng, GAO Dengtao

“…This technology not only simplifies the assessment process but also reduces costs and preserves the integrity of the fruit samples. …”
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Content and boundaries of the primary real estate market as an object of statistical research by Dmitry V. Dianov, Pavel A. Smelov

“…However, issues of managing business processes on the primary market of real estate, including a balance of opportunities for sellers and customer needs, pricing, adequate information support to all management levels, still are a problem and remain open.Purpose. …”
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