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Integration of Single Cell and Bulk RNA-Sequencing Reveals Key Genes and Immune Cell Infiltration to Construct a Predictive Model and Identify Drug Targets in Endometriosis
Published 2025-02-01“…This study aims to explore immune mechanisms and molecular differences in the proliferative eutopic endometrium of endometriosis by integrating bulk RNA-seq and single-cell RNA sequencing (scRNA-seq) data, and to develop diagnostic and predictive models for the disease.Methods: Gene expression profiles from the proliferative endometrium of endometriosis patients and healthy controls were obtained from the Gene Expression Omnibus. …”
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Identification of sepsis biomarkers through glutamine metabolism-mediated immune regulation: a comprehensive analysis employing mendelian randomization, multi-omics integration, an...
Published 2025-08-01“…This study aimed to identify biomarkers of sepsis through an integrated multi-method approach.MethodsMendelian randomization (MR) analysis was performed using data on 1400 plasma metabolites, 731 immune cell phenotypes, and sepsis genome-wide association studies. …”
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943
The Calculation and Analysis of the Total Electron Content Over Different Latitudes and Seasons Using the Numerical Trapezoidal and Simpson Methods
Published 2019-12-01“…In this study, TEC calculation was performed over Baghdad city, Iraq, using a combination of two numerical methods called composite Simpson and composite Trapezoidal methods. …”
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Exploring PID and FOPID Control Methods for Thrust Vectoring in Aerospace Systems-A Beginner’s Guide
Published 2025-01-01“…The performance of two control schemes—Proportional-Integral-Derivative (PID) control and Fractional-Order PID (FOPID) control—is assessed and compared using a systematic manner. …”
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Women's experiences and outcomes of abortion care in sub-Saharan countries: A mixed methods systematic review protocol.
Published 2025-01-01“…These challenges may lead to variations in women's experiences and care outcomes, potentially resulting in adverse physical, psychological, and emotional outcomes for individuals seeking abortions. …”
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Algorithm of video file recognition for digitization of analog indicator oscillations on the example of GNU-KV quartz gravimeter
Published 2024-05-01“…This study explores the use of video technology to enhance the digitization and analysis of gravity field variations using the GNU-KV quartz gravimeter.Materials and methods. …”
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Global and single-nucleotide resolution detection of 7-methylguanosine in RNA
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Real-Time Hand Gesture Recognition in Clinical Settings: A Low-Power FMCW Radar Integrated Sensor System with Multiple Feature Fusion
Published 2025-07-01“…The proposed system integrates velocity profiles, angular variations, and spatial-temporal features through a dual-stage processing architecture: an adaptive energy thresholding detector segments gestures, followed by an attention-enhanced neural classifier. …”
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951
Indirect Measurement Method of Compression Cycle Parameters of Liquid-driven Reciprocating Hydrogen Compressor Based on Vibration Analysis
Published 2024-11-01“…It develops and validates a novel non-direct measurement method that enhances the reliability and efficiency of parameter extraction in liquid-driven reciprocating hydrogen compressors, which are crucial for operational efficiency and diagnostic accuracy in hydrogen fuel systems.Methods The proposed method integrates Variational Time-Domain Decomposition (VTDD), Hilbert transform, and autocorrelation functions to enhance signal analysis and parameter extraction in noisy environments. …”
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Adaptive Control Strategy for Power Flow Controller With Disturbance Mitigation Using Discrete Wavelet Transform in Renewable Energy Source Integrated Railway Systems
Published 2025-01-01“…The growing direct integration of renewable energy sources (RES) into railway power networks has increased their vulnerability to power quality (PQ) disturbances and dynamic variations. …”
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Integrating convolutional neural networks for microscopic image analysis in acute lymphoblastic leukemia classification: A deep learning approach for enhanced diagnostic precision
Published 2024-12-01“…Our fine-tuned ResNet-50 model integrates several additional customized fully connected layers, including dense and dropout layers. …”
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Assessing Impacts of Hydropower Development on Downstream Inundation Using a Hybrid Modeling Framework Integrating Satellite Data‐Driven and Process‐Based Models
Published 2025-03-01“…This study proposes a novel hybrid framework integrating satellite data‐driven Forecasting Inundation Extents using REOF (Rotated Empirical Orthogonal Function) analysis (FIER), and the process‐based Hydrological Predictions for the Environment (HYPE) model incorporating the Integrated Reservoir Operation Scheme (IROS). …”
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Conversational AI agent for precision oncology: AI-HOPE-WNT integrates clinical and genomic data to investigate WNT pathway dysregulation in colorectal cancer
Published 2025-08-01“…To address this gap, we developed AI-HOPE-WNT, the first conversational artificial intelligence (AI) agent purpose-built to investigate WNT signaling in CRC using natural language–driven, integrative bioinformatics.MethodsAI-HOPE-WNT employs a modular architecture combining large language models (LLMs), a natural language-to-code engine, and a backend statistical workflow interfaced with harmonized data from cBioPortal. …”
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