Ultra-broadband coherent open-path spectroscopy for multi-gas monitoring in wastewater treatment by Roderik Krebbers, Kees van Kempen, Yueyu Lin, Joris Meurs, Lisanne Hendriks, Ralf Aben, José R. Paranaiba, Christian Fritz, Annelies J. Veraart, Amir Khodabakhsh, Simona M. Cristescu

“…Wastewater treatment plants significantly contribute to greenhouse gas emissions, including nitrous oxide (N2O), carbon dioxide (CO2), and methane (CH4). Current methods to measure these emissions typically target specific molecular compounds, providing limited scope and potentially incomplete emissions profiles. …”
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Genomic characterization and antibiotic susceptibility of biofilm-forming Borrelia afzelii and Borrelia garinii from patients with erythema migrans by Giorgia Fabrizio, Giorgia Fabrizio, Ilaria Cavallo, Francesca Sivori, Mauro Truglio, Daniela Kovacs, Massimo Francalancia, Giovanna D’Agosto, Elisabetta Trento, Grazia Prignano, Arianna Mastrofrancesco, Eva Ruzič-Sabljič, Fulvia Pimpinelli, Enea Gino Di Domenico

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Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. by Rahul S Desikan, Chun Chieh Fan, Yunpeng Wang, Andrew J Schork, Howard J Cabral, L Adrienne Cupples, Wesley K Thompson, Lilah Besser, Walter A Kukull, Dominic Holland, Chi-Hua Chen, James B Brewer, David S Karow, Karolina Kauppi, Aree Witoelar, Celeste M Karch, Luke W Bonham, Jennifer S Yokoyama, Howard J Rosen, Bruce L Miller, William P Dillon, David M Wilson, Christopher P Hess, Margaret Pericak-Vance, Jonathan L Haines, Lindsay A Farrer, Richard Mayeux, John Hardy, Alison M Goate, Bradley T Hyman, Gerard D Schellenberg, Linda K McEvoy, Ole A Andreassen, Anders M Dale

“…Although genetic studies have identified AD-associated SNPs in APOE and other genes, genetic information has not been integrated into an epidemiological framework for risk prediction.…”
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Comprehensive Analysis of Congenital Aniridia and Differential Diagnoses: Genetic Insights and Clinical Manifestations by Jonathan Hall, Marta Corton, Fabian Norbert Fries, Jessica Obst, Clara Grünauer-Kloevekorn, Berthold Seitz, Maria della Volpe Waizel, Eszter Jávorszky, Kálmán Tory, Erika Maka, Maryam Amini, Shweta Suiwal, Tanja Stachon, Nóra Szentmáry

“…Pathogenic variants in the PAX6 gene are the primary genetic cause of CA, though variations in other genes, including FOXC1, PITX2, CYP1B1, FOXD3, PITX3, CPAMD8, ITPR1, TENM3, TRIM44, COL4A1, CRYAA, and PXDN may also be implicated. …”
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Beyond dietary therapy: addressing weight stigma awareness in medical students by Giuseppe Annunziata, Giordano Bruno Zonzini, Evelyn Frias-Toral, Raynier Zambrano-Villacres, Alexander Bertuccioli, Davide Sisti, Ludovica Verde, Daniele Di Pauli, Annamaria Colao, Giovanna Muscogiuri, Daniel Simancas-Racines, Alessandro Gennaro, Luigi Barrea

“…The analysis explored variations in stigma levels based on gender, BMI classification, nationality, Italian regional location, level of academic education, medical history, and lifestyle factors. …”
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Insights into high-altitude adaptation and meat quality regulation by gastrointestinal metabolites in Tibetan and black pigs by Xue Bai, Xue Bai, Zhiying Huang, Helin Tan, Yiren Gu, Xun Wang, Long Jin, Peng Shang, Keren Long, Diyan Li, Mingzhou Li

“…Our goal was to correlate omic variations with meat quality traits and identify potential biomarkers predictive of superior meat quality, elucidate the regulatory effects of digestive tract microbial metabolites on Tibetan pig muscle characteristics, and reveal the genetic and nutritional mechanisms that promote adaptation to extreme environmental conditions.MethodsThis analysis encompassed metabolomic profiling of the entire digestive tract-including the stomach, jejunum, cecum, colon, and rectum-as well as histological, amino acid, fatty acid composition, and transcriptomic assessments of the longissimus dorsi muscle tissues to investigate how digestive tract microbial metabolites influence muscle adaptation to high altitudes.ResultsAnalyses revealed that Tibetan pig muscles contain smaller, more oxidative fibers enriched with flavor-enhancing amino acids. …”
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Evaluating the long-term impact of a distance learning course on attitudes, skills, practices, and knowledge in gender-affirming healthcare among healthcare professionals in Italy by Matteo Marconi, Ughetta Maria Favazzi, Pietro Carbone, Debora Guerrera, Angela Ruocco, Martina Manoli, Martina Manoli, Cristiana Barbati, Francesca Molinaro, Federica Maria Regini, Andrea Vittozzi, Alfonso Mazzaccara, Marina Pierdominici

“…The findings underscore the need for structural support and integrated reinforcement to embed gender-affirming care into routine practice.…”
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Association of <i>OPRM1</i> and <i>OPRD1</i> Polymorphisms with Pain and Opioid Adverse Reactions in Colorectal Cancer by Carolina Gutiérrez-Cáceres, Nikolas Ávila, Leslie C. Cerpa, Matías F. Martínez, Carlos E. Irarrazabal, Benjamín Torres, Olga Barajas, Nelson M. Varela, Luis A. Quiñones

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RAB5B: explore its carcinogenic potential and understand its role, prognostic value and biological significance in pan-cancer by Jing Zhu, Chun Yu, Xin Xu, Chu Zou, Jiaqi Li, Rui Wang, Xinchao Li, Aijun Sun, Shiyan Wang, Chao Jiang

“…In most malignancies, RAB5B expression correlated positively with Copy Number Variation (CNV) and methylation. It also correlated significantly with immunotherapy biomarkers and responses. …”
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Increasing COVID-19 Testing and Vaccination Uptake in the Take Care Texas Community-Based Randomized Trial: Adaptive Geospatial Analysis by Kehe Zhang, Jocelyn V Hunyadi, Marcia C de Oliveira Otto, Miryoung Lee, Zitong Zhang, Ryan Ramphul, Jose-Miguel Yamal, Ashraf Yaseen, Alanna C Morrison, Shreela Sharma, Mohammad Hossein Rahbar, Xu Zhang, Stephen Linder, Dritana Marko, Rachel White Roy, Deborah Banerjee, Esmeralda Guajardo, Michelle Crum, Belinda Reininger, Maria E Fernandez, Cici Bauer

“…COVID-19 burden presented substantial temporal changes and local variations across CBGs. COVID-19 burden and community disparity exhibited some common geographical patterns but also displayed distinct variations, particularly at different time points throughout this study. …”
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Hyperspectral imaging-driven deep learning approach: Asymptomatic stage detection and severity grading of tomato yellow leaf curl disease by Junzhi Chen, Wenshan Zhong, Xuejun Yue, Ziyu Ding, Mengdan Du, Xuantian Li, Biao Chen, Haifeng Li, ZiFu He, Xiaoman She, Yafei Tang

“…The findings establish that hyperspectral imaging integrated with SSDBRN enables non-destructive, early asymptomatic-stage detection and precise severity classification of TYLCD, providing an efficient diagnostic solution for the agricultural industry.…”
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Deciphering the role of heat shock protein HSPA1L: biomarker discovery and prognostic insights in Parkinson's disease and glioma by Hong Cheng, Jing Wang, Yingjie Zhao, Xiaoli Hou, Fang Ling, Yixia Wang, Yasen Cao

“…Gene Set Variation Analysis (GSVA) was performed to explore functional profiles, while LASSO regression was employed to screen potential PD biomarkers. …”
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Access to Primary Care Telemedicine and Visit Characterization in a Pediatric, Low-Income, Primarily Latino Population: Retrospective Study by Priya R Pathak, Melissa S Stockwell, Mariellen M Lane, Laura Robbins-Milne, Suzanne Friedman, Kalpana Pethe, Margaret C Krause, Karen Soren, Luz Adriana Matiz, Lauren B Solomon, Maria E Burke, Edith Bracho-Sanchez

“…Telemedicine diagnoses were categorized, and subanalyses were conducted to explore variations by age and month. ResultsThere were 12,377 unique patients and 7127 telemedicine visits. …”
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Enhancing Food Safety: Adapting to Microbial Responses Under Diverse Environmental Stressors by Imran Mohammad, Mohammed Sarosh Khan, Mohammad Rizwan Ansari, Mohammad Azhar Kamal, Mohammad Nadeem Bari, Mohammad Anwar

“…At the same time, microbial adaptation is an integral part of ecosystem functioning, profoundly influencing processes such as nutrient cycling, decomposition, and soil fertility. …”
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Deep learning radiomics based on contrast enhanced MRI for preoperatively predicting early recurrence in hepatocellular carcinoma after curative resection by Ying Zhao, Sen Wang, Sen Wang, Yue Wang, Jun Li, Jinghong Liu, Yuhui Liu, Haitong Ji, Wenhan Su, Qinhe Zhang, Qingwei Song, Yu Yao, Yu Yao, Ailian Liu, Ailian Liu

“…PurposeTo explore the role of deep learning (DL) and radiomics-based integrated approach based on contrast enhanced magnetic resonance imaging (CEMRI) for predicting early recurrence (ER) in hepatocellular carcinoma (HCC) patients after curative resection.MethodsTotal 165 HCC patients (ER, n = 96 vs. non-early recurrence (NER), n = 69) were retrospectively collected and divided into a training cohort (n = 132) and a validation cohort (n = 33). …”
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Impact of nonsynonymous single nucleotide polymorphisms in PROCR gene on protein stability and thrombotic risk: a molecular dynamic approach by Hytham Ahmed Abuagla, Khalid Mohamed Adam, Mohamed E. Elangeeb, Elsadig Mohamed Ahmed, Elshazali W. Ali, Ali M. Edris, Abubakr Ali Elamin MohamedAhmed, Elmoiz Idris Eltieb, Tarig Babikir Algak Khalid, Bahaeldin K. Elamin, Hiba Mahgoub Ali Osman, Ebtehal Salih Idris

“…These mutations may disrupt EPCR stability and impair its anticoagulant function, thereby increasing the risk of thrombosis.MethodsWe employed a multi-layered computational approach to analyze 217 nsSNPs in the PROCR gene. …”
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Application of fourier transform infrared vibrational spectroscopy in identifying early biochemical changes in lipid profiles of individuals undergoing Roux-en-y gastric bypass by Amanda Motta de Bortoli, Márcia Helena Cassago Nascimento, Blanca Elena Guerrero Daboin, Beatriz Bobbio de Brito, Luiza Recla Pessotti, Paulo Roberto Filgueiras, Andressa Bolsoni Lopes, Valerio Garrone Barauna, Fabiano Kenji Haraguchi

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The impact of social and commercial determinants on the unequal increase of oral disorder disease burdens across global, regional, and national contexts by Yongqiang Lai, Ye Li, Xinwei Liu, Yuanxiang Shi, Fangqi Qu, Xiyu Zhang, Baoguo Shi, Xiaohe Wang, Tao Sun, Xianhong Huang, Dingyun You

“…Policy efforts should prioritize intersectoral actions to regulate harmful commercial practices, strengthen primary oral health care in underserved regions, and integrate oral health into universal health coverage frameworks. …”
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Investigation of a chest radiograph-based deep learning model to identify an imaging biomarker for malnutrition in older adults by Ryo Sasaki, Yasuhiko Nakao, Fumihiro Mawatari, Takahito Nishihara, Masafumi Haraguchi, Masanori Fukushima, Ryu Sasaki, Satoshi Miuma, Hisamitsu Miyaaki, Kazuhiko Nakao

“…It is anticipated that AI will be integrated into the NST workflow in the future.…”
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Dietary Variability Among Mountain Gorilla Groups Across Volcanoes National Park, Rwanda by H. Ihimbazwe, J. D. Tuyizere, L. Kayitete, D. Abavandimwe, A. K. Kamanzi Shimwa, M. L. Power, C. C. Grueter, M. Flint, J. D. Nsanzineza, A. Jonas, G. Kwibuka, D. Ishimwe, F. Ndagijimana, J. D. Hakizimana, P. Uwingeli, S. C. McFarlin, M. M. Robbins, T. S. Stoinski, W. Eckardt

“…Building on previous efforts, we describe dietary variability among VNP mountain gorilla groups by integrating data from groups ranging in the northeast VNP. …”
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