Spatial and Temporal Evolution Assessment of Landscape Ecological Resilience Based on Adaptive Cycling in Changsha–Zhuzhou–Xiangtan Urban Agglomeration, China by Huaizhen Peng, Huachao Lou, Yifan Liu, Qingying He, Maomao Zhang, Ying Yang

“…This framework applies exploratory spatial data analysis methods to examine the spatiotemporal evolution and associated patterns of resilience and the Geodetector model to measure the driving factors of spatial variation. …”
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Calculation of COVID-19 disease burden using Monte Carlo simulation with dynamic disability weights and analysis of transmission characteristics by Wenxiu Chen, Wei An, Qun Gao, Ji Bai, Hua Li, Song Tang, Wenhui Gao, Zhe Tian, Yu Zhang, Min Yang

“…These distributions were integrated into Monte Carlo simulations to model real-time disease burden, offering robust data to support evidence-based policy decisions and optimize resource allocation. …”
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Utilization of Ultrasonic-Assisted Extraction for Bioactive Compounds from Floral Sources by Sepidar Seyyedi-Mansour, Pauline Donn, Maria Carpena, Franklin Chamorro, Paula Barciela, Ana Perez-Vazquez, Ana Olivia S. Jorge, Miguel A. Prieto

“…The findings also highlight the importance of parameter optimization, as variations in solvent concentration and ultrasonic intensity can affect the structural integrity of extracted compounds. …”
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Persistent monitoring of insect-pests on sticky traps through hierarchical transfer learning and slicing-aided hyper inference by Fateme Fotouhi, Fateme Fotouhi, Kevin Menke, Aaron Prestholt, Ashish Gupta, Matthew E. Carroll, Hsin-Jung Yang, Edwin J. Skidmore, Matthew O’Neal, Nirav Merchant, Sajal K. Das, Peter Kyveryga, Baskar Ganapathysubramanian, Baskar Ganapathysubramanian, Asheesh K. Singh, Arti Singh, Soumik Sarkar, Soumik Sarkar

“…However, this task is fraught with complexities, encompassing challenges such as, laborious dataset annotation, recognizing small insect-pests in low-resolution or distant images, and the intricate variations across insect-pests life stages and species classes.MethodsTo tackle these obstacles, this work investigates combining two solutions, Hierarchical Transfer Learning (HTL) and Slicing-Aided Hyper Inference (SAHI), along with applying a detection model. …”
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Evaluating the association of transient receptor potential cation channel subfamily A member 1 gene polymorphisms with pain sensitivity: results from an adaptive recall by genotype... by Aidan P. Nickerson, Laura J. Corbin, Nicholas J. Timpson, Megan Nott, Oliver Blanshard, Katie Foy, Fang Fang Quek, Christopher Geddie, Keith Phillips, Frances M.K. Williams, Anthony E. Pickering, James P. Dunham

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Characteristics of serum bile acid profiles among individuals with metabolic dysfunction-associated steatotic liver disease by Sheng Lyu, Jiani Yang, Xin Xin, Qinmei Sun, Beiyu Cai, Xin Wang, Ziming An, Jian Sun, Yiyang Hu, Lei Shi, Qin Feng, Xiaojun Gou

“…In this multicenter clinical study, we aimed to characterize serum BA profiles in patients with MASLD and identify specific alterations compared to healthy controls. Methods All MASLD cases were sourced from the gastroenterology outpatient departments of Shanghai Baoshan Hospital of Integrated Chinese and Western Medicine, Shanghai Baoshan District Songnan Community Health Service Center, and Lianyungang Oriental Hospital between June 2015 and December 2019. …”
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Re‐Striking the Indications in the Improvement of Avoidable Caesarian Section: A Cluster Randomized Control Trial by Fatema Ashraf, Jobaida Sultana, MSA Mansur Ahmed, Khadija Mannan, Moomtahina Fatima, Mintu Chowdhury, Jinnat Ara Islam, Khandaker Shehneela Tasmin, Adneen Moureen, Md. Abdullah Yusuf, Redoy Ranjan, Md. Nazmul Karim

“…Conclusion Re‐striking the primary indications for cesarean sections is crucial for reducing avoidable deliveries; that is why it should be integrated into hospital policy to benefit patients and the healthcare system.…”
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AI-driven online adaptive radiotherapy in prostate cancer treatment: considerations on activity time and dosimetric benefits by Francesco Preziosi, Althea Boschetti, Francesco Catucci, Claudio Votta, Luca Vellini, Sebastiano Menna, Flaviovincenzo Quaranta, Elisa Pilloni, Andrea D’Aviero, Michele Aquilano, Carmela Di Dio, Martina Iezzi, Alessia Re, Antonio Piras, Marco Marras, Francesca Gruosso, Domenico Piro, Danila Piccari, Luca Tagliaferri, Maria Antonietta Gambacorta, Luca Indovina, Gian Carlo Mattiucci, Davide Cusumano

“…Abstract Aims Recent advances in Radiotherapy have led to the development of online adaptive RT (oART), a procedure addressing inter-fraction anatomical variations. Integrating artificial intelligence (AI) into the oART procedure speeds up the process and reduces user dependency. …”
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Defining Nephritic Factors as Diverse Drivers of Systemic Complement Dysregulation in C3 Glomerulopathy by Jill J. Hauer, Yuzhou Zhang, Renee Goodfellow, Amanda Taylor, Nicole C. Meyer, Sarah Roberts, Dingwu Shao, Lauren Fergus, Nicolo Ghiringhelli Borsa, Monica Hall, Carla M. Nester, Richard J.H. Smith

“…Rare and novel genetic variation in complement genes and autoantibodies to complement proteins are commonly identified in the C3G population and thought to drive the underlying complement dysregulation that results in renal damage. …”
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Cathepsin L in Lung Adenocarcinoma: Prognostic Significance and Immunotherapy Response Through a Multi Omics Perspective by Jianming Lu, Jiaqi Liang, Gang Xiao, Zitao He, Guifang Yu, Le Zhang, Chao Cai, Gao Yi, Jianjiang Xie

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Numerical and experimental evaluation of shear strength and consolidation properties of cohesive soils in high water table areas by Nauman Izhar, Muhammad Adeel Khan, Muhammad Salman Khan, Asad Khan, Mahmood Ahmad, Mahmood Ahmad, Mohanad Muayad Sabri Sabri, Muriuzs Necurzac, Abdullah Alzlfawi

“…The numerical results from PLAXIS offered a more accurate understanding of soil behavior compared to the traditional Meyerhof and Vesic methods, highlighting the necessity of integrating advanced numerical techniques with conventional approaches. …”
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Master protocol for a series of cohort-based randomized controlled trials to test tools to communicate research results to study participants and others with relevant lived experie... by Brett D. Thombs, Claire Adams, Elsa-Lynn Nassar, Marie-Eve Carrier, Meira Golberg, Kanika Bharthi, Amanda Wurz, Annabelle South, Linda Kwakkenbos, Sabrina Hoa, Danielle B. Rice, Geneviève Guillot, Amanda Lawrie-Jones, Maureen Sauvé, Susan J. Bartlett, Catherine Fortune, Amy Gietzen, Karen Gottesman, Marie Hudson, Laura K. Hummers, Vanessa L. Malcarne, Maureen D. Mayes, Michelle Richard, James Stempel, Robyn K. Wojeck, Kathleen Blagrave, Jill T. Boruff, Vanessa Cook, Nicole Culos-Reed, Ole Fröbert, Katie Gillies, Vera Granikov, Lars G. Hemkens, Elizabeth Yakes Jimenez, Agnes Kocher, Catarina Leite, Mathew A. W. T. Lim, Nancy Maltez, John Michalski, Tracy Mieszczak, Mwidimi Ndosi, Janet Pope, François Rannou, Ken Rozee, Sharon E. Straus, Matthew R. Sydes, Lehana Thabane, John Varga, Tami Yap, Merrick Zwarenstein, Luc Mouthon, Andrea Benedetti, SPIN Investigators

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Robust Image Population Based Stain Color Normalization: How Many Reference Slides Are Enough? by Jose L. Agraz, Caleb M. Grenko, Andrew A. Chen, Angela N. Viaene, MacLean D. Nasrallah, Sarthak Pati, Tahsin Kurc, Joel Saltz, Michael D. Feldman, Hamed Akbari, Parth Sharma, Russell T. Shinohara, Spyridon Bakas

“…Aggregate-based stain normalization may contribute in increasing computational pathology robustness, reproducibility, and integrity.…”
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MentalAId: an improved DenseNet model to assist scalable psychosis assessment by Muxi Li, Farong Liu, Fei Du, Guolin Hong, Qing Hu, Zhi-Liang Ji, Pan You

“…By requiring standard blood tests solely, it can be easily integrated into existing healthcare workflow. This empowers long-term and population-wide monitoring of disease progression and prognosis, particularly during public health crises like COVID-19.…”
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Dental biofilm serves as an ecological reservoir of acidogenic pathobionts in head and neck cancer patients with radiotherapy-related caries by Julia S. Bruno, Vitor Heidrich, Felipe C. F. Restini, Tatiana M. M. T. Alves, Wanessa Miranda-Silva, Franciele H. Knebel, Elisangela M. Cóser, Lilian T. Inoue, Paula F. Asprino, Anamaria A. Camargo, Eduardo R. Fregnani

“…Leveraging shotgun metagenomics, we characterize the unique microbial variations in in vivo irradiated dental biofilms, unveiling novel insights into the microbial ecology of radiotherapy-treated patients. …”
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Characterising developmental dynamics of adult epigenetic clock sitesResearch in context by Rosa H. Mulder, Alexander Neumann, Janine F. Felix, Matthew Suderman, Charlotte A.M. Cecil

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Single-cell transcriptomic profiling reveals the heterogeneity of epithelial cells in lung adenocarcinoma lymph node metastasis and develops a prognostic signature by Qiuqiao Mu, Qiuqiao Mu, Qiuqiao Mu, Han Zhang, Ying Shi, Mengli Xue, Jingxian Wang, Yun Ding, Lin Tan, Hui Yuan, Xin Li, Xin Li, Daqiang Sun, Daqiang Sun, Daqiang Sun

“…Malignant epithelial cells were identified via inferred copy number variation (CNV) profiles. Key malignant subpopulations were further characterized through trajectory inference, cell–cell communication mapping, gene set variation analysis (GSVA), and reconstruction of transcription factor regulatory networks. …”
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Approach to signal loss in intraoperative nerve monitoring in thyroid surgery questionnaire: a Turkish surgical perspective by Yalin Iscan, Irem Karatas, Nurcihan Aygun, Ahmet Cem Dural, Serkan Teksoz, Ozer Makay, Ali Uğur Emre, Fatih Tunca, Mehmet Uludag, Gökhan İçöz, Yasemin Giles Senyürek, Adnan Işgör, Mehmet Haciyanli

“…Further studies are needed to determine the medical-legal implications and effects of these variations.…”
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Assessment of water ecological health in shallow lakes: A new framework based on water resource-environment-ecology by Yanru Tao, Qiujin Xu, Mingke Luo, Wenjing Dong, Yan Pang

“…In lake ecosystems, human disturbances can severely damage ecological integrity, particularly in shallow lakes. Existing research on water ecological health (WEH) assessment has often overlooked critical aspects such as water resources, water environment, and water ecology, which makes the previous research methods less effective. …”
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Sensitivity analysis of the INRA 2018 feeding system for ruminants by hybrid local and global approaches: Comparing the contribution of dietary input variables to multiple response... by Seoyoung Jeon, Tristan Senga Kiessé, Sophie Lemosquet, Pierre Nozière

“…Hence, hybridizing the SA methods can help to interpret the system and facilitate a more precise evaluation thereof, especially GSA, which is amenable to nonmonotonic models such as those characterizing complex feeding systems integrating multiple nutritional and animal factors.…”
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