Integrated morphophysiological, transcriptomic, and metabolomic data uncover the molecular mechanism of environmental adaptation of Zanthoxylum armatum with different latitudinal g... by Yuan Guo, Xueqian Fu, Chong Sun, Chong Sun, Yifei Deng, Han Liu, Long Tong, Mi Kuang, Ning Tang, Wenying Yang, Xia Liu, Zexiong Chen

“…However, adaptive differences under diverse environmental conditions and their molecular mechanisms have not been systematically studied.MethodsPlant materials of Z. armatum from three regions (Shandong, Chongqing, and Yunnan) representing different latitudinal backgrounds were cultivated under uniform conditions. …”
Get full text

The Least Limiting Water Range to Estimate Soil Water Content Using Random Forest Integrated with GIS and Geostatistical Approaches by Orhan Dengiz, Pelin Alaboz

Get full text

Impact of Health and Health-Related Domains on Professionals’ Perceptions of Care Complexity, Their Preferences for Integrated Care Planning and Interprofessional Collaboration by Lisa-Maria van Klaveren, Vincent G. M. Geukers, Rien de Vos

“…Methods: Ninety-eight medical doctors and nursing professionals assessed care complexity, integrated care planning needs, and interprofessional collaboration using thirteen paper cases based on five domains from the International Classification for Functioning (ICF). …”
Get full text

Integrative Bioinformatic Analysis of Cellular Senescence Genes in Ovarian Cancer: Molecular Subtyping, Prognostic Risk Stratification, and Chemoresistance Prediction by Ailian Li, Dianbo Xu

“…Cellular senescence-related genes (CSGs) are emerging as pivotal regulators of tumorigenesis and immune modulation, yet their prognostic and therapeutic implications in OC remain underexplored. <b>Methods</b>: We integrated RNA-sequencing data from TCGA-OV (n = 376), GTEx (n = 88), and GSE26712 (n = 185) to identify differentially expressed CSGs (DE-CSGs). …”
Get full text

Detecting cell-type-specific allelic expression imbalance by integrative analysis of bulk and single-cell RNA sequencing data. by Jiaxin Fan, Xuran Wang, Rui Xiao, Mingyao Li

“…Allelic expression imbalance (AEI), quantified by the relative expression of two alleles of a gene in a diploid organism, can help explain phenotypic variations among individuals. Traditional methods detect AEI using bulk RNA sequencing (RNA-seq) data, a data type that averages out cell-to-cell heterogeneity in gene expression across cell types. …”
Get full text

Exercise-changed gut mycobiome as a potential contributor to metabolic benefits in diabetes prevention: an integrative multi-omics study by Yao Wang, Jiarui Chen, Yueqiong Ni, Yan Liu, Xiang Gao, Michael Andrew Tse, Gianni Panagiotou, Aimin Xu

“…With our established randomized controlled trial of exercise intervention in Chinese males with prediabetes (n = 39, ClinicalTrials.gov:NCT03240978), we investigated the dynamics of human gut mycobiome and further interrogated their associations with exercise-elicited outcomes using multi-omics approaches.Methods Clinical variations and biological samples were collected before and after training. …”
Get full text

Higher blood pressure variability during hospitalisation is associated with lower cerebral white matter integrity in COVID-19 patients by Theresa J. van Lith, Esther Janssen, Jan-Willem van Dalen, Hao Li, Mats Koeneman, Wouter M. Sluis, Naomi T. Wijers, Marieke J. H. Wermer, Menno V. Huisman, H. Bart van der Worp, Frederick J. A. Meijer, Anil M. Tuladhar, Sebastian J. H. Bredie, Frank-Erik de Leeuw

“…We examined whether BPV, measured in-hospital using continuous monitoring, is associated with WM microstructural integrity in COVID-19 patients.Methods We included hospitalised COVID-19 patients from the CORONavirus and Ischemic Stroke (CORONIS) study who underwent continuous vital signs monitoring using a wearable device during hospital admission and had an MRI shortly after discharge. …”
Get full text

Ecological Momentary Assessment of Self-Harm Thoughts and Behaviors: Systematic Review of Constructs From the Integrated Motivational-Volitional Model by Lizzy Winstone, Jon Heron, Ann John, Olivia J Kirtley, Paul Moran, Jennifer Muehlenkamp, Rory C O'Connor, Becky Mars

“… BackgroundThe integrated motivational-volitional model (IMV) is one of the leading theoretical models of suicidal thoughts and behavior. …”
Get full text

Integrative molecular subtyping and diagnostic model construction for Moyamoya disease based on diverse programmed cell death gene patterns by Qikai Tang, Chenfeng Ma, Hu Li, Jiaheng Xie, Weiqi Bian, Qingyu Lu, Zeyu Wan, Wei Wu

“…Abstract Background The role of cell death in the pathogenesis of Moyamoya disease (MMD) remains unclear. Methods Gene expression data from two publicly available MMD datasets (GSE157628 and GSE189993) were integrated. …”
Get full text

Integrated transcriptomic and immune profiling reveals crucial molecular pathways and hub genes associated with postoperative delirium in elderly patients by Zi-han Gou, Nan Su, Xiao-chuan Li, Da-peng Ren, Shan-shan Ren, Lin Wang, Yao Wang

Get full text

Sperm protein profiles and their correlation with DNA integrity and protamine deficiency in Donggala bulls (Bos indicus): Implications for fertility assessment by Abdullah Baharun, Hikmayani Iskandar, Tulus Maulana, Annisa Rahmi, Ristika Handarini, Ikhsan Qodri Pramartaa, Fitra Aji Pamungkas, Daud Samsudewa, Ekayanti Mulyawati Kaiin, Paskah Partogi Agung, Muhammad Gunawan, Yulius Duma, Raden Iis Arifiantini, Syahruddin Said

“…This study aimed to characterize the sperm protein profiles of Donggala bulls and examine their correlation with sperm DNA integrity and protamine deficiency. Materials and Methods: Frozen semen samples were collected from six Donggala bulls (aged 5–7 years). …”
Get full text

Integrative analysis of bulk and single-cell RNA sequencing data reveals increased arachidonic acid metabolism in osteoarthritic chondrocytes by Kan Wu, Zhaoqian Zhong, Li Chen, Haihua Luo, Aolin Jiang, Linlin Tao, Yong Jiang

Get full text

Accurate GRACE terrestrial water storage estimations via a new fusion method by Min Dai, Hao Zhou, Wenjing Ma, Shuyun Zheng, Mingyang Xia, Yaozong Li, Zhicai Luo

“…We employ the generalized three-cornered hat (GTCH) method to quantify uncertainties of different GRACE products and integrate it with the Bayesian model averaging (BMA) method to construct a new fusion algorithm, GTCH+BMA, which generates integrated TWS products. …”
Get full text

Improved Hourly Cooling and Heating Load Analysis Using Residential Load Factor Method by Fazli Yazdan, Usman Ur Rehman, Fakhre Alam Khan, Naveed Ahmad, Afzal Khan, Zahid Ullah

“…The proposed method integrates with the well-established residential load factor framework, capturing the dynamic influence of temperature variations on energy use. …”
Get full text

A New Customized Measurement System for a Non-Contact, Enhanced Thermometric Method by Luca Evangelisti, Edoardo De Cristo, Salvatore Monteleone, Claudia Guattari, Paola Gori, Ivan Pini, Tullio de Rubeis, Dario Ambrosini

“…This study introduces a novel, low-cost, non-contact measurement system for heat flux estimation based on an enhanced thermometric method. The customized system was designed and assembled to implement a non-contact, indirect approach for heat flux assessment. …”
Get full text

Remaining Useful Life Prediction Method for Stochastic Degrading Devices Considering Predictive Maintenance by Qing Dong, Hong Pei, Changhua Hu, Jianfei Zheng, Dangbo Du

“…Secondly, a method is proposed for model parameter identification and updating that incorporates the individual variation among devices, integrating maximum likelihood estimation and Bayesian inference. …”
Get full text

An Improved Man-Made Structure Detection Method for Multi-aspect Polarimetric SAR Data by Fabin Dong, Qiang Yin, Wen Hong

“…Therefore, this article proposes an improved man-made structure detection method that integrates scattering power characteristics and anisotropic features. …”
Get full text

A Method for Identifying Thin Interbedded Lithological Interfaces Based on the Combination of Wavelet and Deconvolution by LI Zhipeng, HUANG Lisha, YAN Jianping, YANG Minglin, WU Hongcui, WANG Min

“…To accurately identify the layering interfaces of thin interbedded lithology, we propose a method that integrates wavelet analysis with deconvolution, approaching it from the perspectives of logging information acquisition resolution and signal analysis. …”
Get full text

A Dehazing Method for UAV Remote Sensing Based on Global and Local Feature Collaboration by Chenyang Li, Suiping Zhou, Ting Wu, Jiaqi Shi, Feng Guo

“…A Transformer-based Multi-layer Global Information Capturing (MGIC) module is introduced to progressively capture and integrate global contextual features across multiple layers, enabling the model to perceive and adapt to spatial variations in haze distribution. …”
Get full text

Screening cotton cultivars for low-phosphorus tolerance: a comparison of hydroponic and field methods by Miao Sun, Helin Dong, Huimin Han, Weina Feng, Jingjing Shao, Feichao Huo, Pengcheng Li, Cangsong Zheng

Get full text