Integration of single-cell RNA and bulk RNA sequencing revealed malignant ductal cell heterogeneity and prognosis signatures in pancreatic cancer by Haiyang Du, Haiyang Du, Gao Si, Jiqing Si, Xuejie Song, Xuejie Song, Fuchun Si, Fuchun Si

“…Large-scale chromosomal copy-number variation (CNV) analysis distinguished malignant from non-malignant ductal cells. …”
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MESM: integrating multi-source data for high-accuracy protein-protein interactions prediction through multimodal language models by Feng Wang, Jinming Chu, Liyan Shen, Shan Chang

“…MESM consists of three key modules, as follows: First, MESM extracts multimodal representations from protein sequence information, protein structure information, and point cloud features through Sequence Variational Autoencoder (SVAE), Variational Graph Autoencoder (VGAE), and PointNet Autoencoder (PAE). …”
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Nanoparticles in Plant Cryopreservation: Effects on Genetic Stability, Metabolic Profiles, and Structural Integrity in Bleeding Heart (Papaveraceae) Cultivars by Kulus D, Tymoszuk A, Kulpińska A, Dębska B, Michalska A, Nowakowska J, Wichrowska D, Wojnarowicz J, Szałaj U

“…This research investigated the effects of gold (AuNPs), silver (AgNPs), and zinc oxide (ZnONPs) nanoparticles on the structural integrity, genetic stability, and metabolic activity of cryopreserved plant materials with medicinal properties.Methods: Shoot tips from two bleeding heart (Lamprocapnos spectabilis (L). …”
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Integrating life cycle assessment into green infrastructure: a systematic review and meta-analysis of urban sustainability strategies by Negin Bani Khalifi, Dafni Despoina Avgoustaki, Thomas Bartzanas

“…However, the inconsistent use of life cycle assessment (LCA) methods—including variations in impact categories, data collection methods, system boundaries, and functional units—hinders effective policymaking and comparison among projects. …”
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Remote Sensing Image Segmentation Network That Integrates Global–Local Multi-Scale Information with Deep and Shallow Features by Nan Chen, Ruiqi Yang, Yili Zhao, Qinling Dai, Leiguang Wang

“…Extensive ablation and comparative experiments conducted on two public remote sensing datasets, ISPRS Vaihingen and Potsdam, demonstrate that our proposed GLDSFNet outperforms state-of-the-art methods.…”
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CHARACTERIZATION OF SUBSURFACE LITHOLOGICAL UNITS AND AQUIFEROUS FORMATIONS USING INTEGRATED VLF AND VES TECHNIQUES IN OWO, ONDO STATE by Nosayaba Avenbuan, , Olalekan Ayodeji Omolegan, Diemeta Ikperikpe

“…This study applies integrated Very Low Frequency (VLF) electromagnetic profiling and Vertical Electrical Sounding (VES) to delineate groundwater potential zones in Owo, Ondo State, Nigeria. …”
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AI-powered smart hydrological measurement using deep vision integrated with BeiDou high precision positioning by Zhiqiang He, Dongxiang Zhang, Qian Wang

“…As per the early investigations, most modern methods struggle with significant limitations regarding precise monitoring and tracking ability. …”
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An Integrated Deep Learning Model with EfficientNet and ResNet for Accurate Multi-Class Skin Disease Classification by Madallah Alruwaili, Mahmood Mohamed

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Research on control strategies for low-pressure components in integrated thermal management systems based on optimal coefficient of performance by Rongjiang Tang, Lei Guan, Cheng Xu, Yanhong Wei, Xianming Meng, Bin Jia, Shuhan Wen

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Integrated distribution modeling resolves asynchrony between bat population impacts and occupancy trends through latent abundance by Bradley J. Udell, Christian Stratton, Kathryn M. Irvine, Bethany Rose Straw, Jonathan D. Reichard, Sarah Gaulke, Jeremy. T. H. Coleman, Frank C. Tousley, Andrea N. Schuhmann, Richard D. Inman, Melinda Turner, Sarah Nystrom, Brian E. Reichert

“…The asynchrony between occupancy trends and population impacts was explained as an emergent pattern of spatiotemporal variation in abundance in the integrated distribution model. …”
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Phenotypic Diversity Analysis and Integrative Evaluation of <i>Camellia oleifera</i> Germplasm Resources in Ya’an, Sichuan Province by Shiheng Zheng, Qingbo Kong, Hanrui Yan, Junjie Liu, Renke Tang, Lijun Zhou, Hongyu Yang, Xiaoyu Jiang, Shiling Feng, Chunbang Ding, Tao Chen

“…Quantitative traits were classified morphologically, and correlation analysis integrated them into 13 key indicators classified using LSD and range methods. …”
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Machine learning integrates region-specific microbial signatures to distinguish geographically adjacent populations within a province by Li Luo, Li Luo, Bangwei Chen, Bangwei Chen, Shengyin Zeng, Shengyin Zeng, Yaxin Li, Yaxin Li, Xiaolin Chen, Xiaolin Chen, Jianguo Zhang, Xiangjie Guo, Shujin Li, Lei Ruan, Shida Zhu, Cairong Gao, Cuntai Zhang, Tao Li

“…However, the gut microbiota variations among people residing in different regions within a province remain enigmatic.MethodsShotgun metagenomics sequencing was performed to analyze the gut microbiota of 381 unrelated Chinese Han individuals living in two cities (Wuhan and Shiyan) of Hubei Province. …”
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The protocol for developing health and disease prevention services: An exercise-based prediction model integrating genomic test results. by Yunsuk Choi, Hyunseok Jee

“…This protocol outlines a study aimed at integrating genomic analysis and personalized exercise interventions to improve health outcomes and reduce cancer-related risk factors. …”
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Semicontinuous Blending of Pharmaceutical Ingredients and the Impact of Process Parameters on the Blending Performance of an Integrated Feeder Blender Operating Semicontinuously by Sumit Kumar, Yan-Shu Huang, Zoltan Nagy, Gintaras V. Reklaitis, Marcial Gonzalez, Paul Mort

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CISMN: A Chaos-Integrated Synaptic-Memory Network with Multi-Compartment Chaotic Dynamics for Robust Nonlinear Regression by Yaser Shahbazi, Mohsen Mokhtari Kashavar, Abbas Ghaffari, Mohammad Fotouhi, Siamak Pedrammehr

“…CISMN sustains gradient norms (~2300) versus LSTM collapse (<3), and fixed-seed protocols ensure <1.2% MAE variation. Interpretability remains challenging (feature-attribution entropy ≈ 2.58 bits), motivating future hybrid explanation methods. …”
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Integrating electrical resistivity tomography and x-ray fluorescence for characterizing limestone in the Wapulaka Formation, Central Buton, Indonesia by Erfan Syamsuddin, Adi Maulana, Alimuddin Hamzah Assegaf, Ulva Ria Irfan

“…This study illustrates the efficacy of integrating geophysical and geochemical methods to delineate intricate carbonate systems, providing insights into subsurface heterogeneity, diagenetic processes, and resource availability.…”
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Integrated omics profiling reveals systemic dysregulation and potential biomarkers in the blood of patients with neuromyelitis optica spectrum disorders by Zuoquan Xie, Qinming Zhou, Jin Hu, Lu He, Huangyu Meng, Xiaoni Liu, Guangqiang Sun, Zhiyu Luo, Yuan Feng, Liang Li, Xingkun Chu, Chen Du, Dabing Yang, Xinying Yang, Jing Zhang, Changrong Ge, Xiang Zhang, Sheng Chen, Meiyu Geng

“…Additionally, we unveiled the variations in peripheral features among different clinical subgroups within NMOSD. …”
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Integrating clinical data and genetic susceptibility to elucidate the relationship between systemic lupus erythematosus and human cytomegalovirus infection by Xin Luo, Liuliu Quan, Qingting Lin, Huiteng Rong, Yue Liu, Jiaqi Meng, Xin You

“…Methods Using various statistical methods, we conducted a retrospective analysis of the spectrum of SLE autoantibodies and HCMV infections among patients hospitalized at our center over the past 10 years. …”
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CCL26 as a prognostic biomarker in hepatocellular carcinoma: integrating bioinformatics analysis, clinical validation, and radiomics score by Junjun Yan, Qiangming Liao, Yong Xie, Sihai Chen

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Integrated Multi-Omics Profiling Reveals That Highly Pyroptotic MDMs Contribute to Psoriasis Progression Through CXCL16 by Liping Jin, Xiaowen Xie, Mi Zhang, Wu Zhu, Guanxiong Zhang, Wangqing Chen

“…<b>Objective:</b> To investigate cell-type-specific pyroptosis patterns in psoriasis and their immunoregulatory mechanisms. <b>Methods:</b> We integrated 21 transcriptomic datasets (from 2007 to 2020) obtained from the GEO database and two single-cell RNA sequencing datasets to quantify pyroptotic activity using Gene Set Variation Analysis and AUCell algorithms. …”
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