Advances in Mendelian Randomization Studies of Obesity Over the Past Decade: Uncovering Key Genetic Mechanisms by Lu X, Ji L, Chen D, Lian X, Yuan M

“…Future research that integrates multi-ancestry GWAS, functional validation, and multi-omics approaches may further enhance the utility of Mendelian randomization. …”
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Gain of bipolar disorder-related lncRNA AP1AR-DT in mice induces depressive and anxiety-like behaviors by reducing Negr1-mediated excitatory synaptic transmission by Shufen Li, Hongyu Ni, Yaping Wang, Xiaohui Wu, Jianqiang Bi, Haiyan Ou, Zhongwei Li, Junjiao Ping, Zhongju Wang, Renhao Chen, Qiong Yang, Meijun Jiang, Liping Cao, Tingyun Jiang, Siqiang Ren, Cunyou Zhao

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A universal application of the general integral transform: New technique for the analysis of nonlinear oscillator systems by Jing-Yan Niu

“…The Lagrange multiplier is formulated and the new iterative format for the correction functional of the variational iteration method is given by the general integral transformation. …”
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GNSS integrated displacement and attitude determination for structural health monitoring of long-span bridges by Xiangdong An, Xiaolin Meng, Liangliang Hu, Yilin Xie, Fan Zhang, Shuguo Pan

“…This paper presents an integrated displacement and attitude determination approach for bridge health monitoring, leveraging Global Navigation Satellite System (GNSS) technology to simultaneously capture displacement and attitude variations, such as pitch and heading angles. …”
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Optimized decomposition and identification method for multiple power quality disturbances by Wang Zhaoqing, Chang Yanzhao, Chen Jianlei, Bao Weiyu

“…Initially, an improved variational mode decomposition (IVMD) method is presented, leveraging an energy ratio criterion for precise decomposition of concurrent PQDs. …”
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Multiscale Dissection of Spatial Heterogeneity by Integrating Multi‐Slice Spatial and Single‐Cell Transcriptomics by Yuqi Chen, Caiwei Zhen, Yuanyuan Mo, Juan Liu, Lihua Zhang

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Dynamic pricing strategy of low-carbon integrated energy system considering multiple uncertainties by BIAN Xinyi, FAN Hong, ZENG Bo

“…The improved differential evolution method of double variation is used in combination with YEMIP and CPLEX tools for simulation in MATLAB, and the results verify that the model can not only better balance the interests of comprehensive energy operators and load aggregators, but also effectively reduce carbon emissions and improve the ability of the system to deal with uncertain risks.…”
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An Improved Whale Optimization Algorithm for the Integrated Scheduling of Automated Guided Vehicles and Yard Cranes by Shuaishuai Gong, Ping Lou, Jianmin Hu, Yuhang Zeng, Chuannian Fan

“…This validates the superiority of the proposed method.…”
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Centroid Jamming Strategy for Reconnaissance and Strike Integrated UAV Based on Chaff Cartridge Protection by Qing Chaojin, He Linsi, Wei Maogang, Wang Zilong

“…The simulation results demonstrate that under the given initial distance and escape time conditions, the closest distance between the missile and the RSUAV increases to more than 127 times of the missile explosion range, and prolongs the survival time of the RSUAV by about 62.5%. The proposed method can help to improve the survival probability of RSUAV, and it presents the effectiveness and robustness with the parameters variations of missile, chaff cartridge, and environmental conditions.…”
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ED-Swin Transformer: A Cassava Disease Classification Model Integrated with UAV Images by Jing Zhang, Hao Zhou, Kunyu Liu, Yuguang Xu

“…Traditional manual monitoring methods are limited by efficiency bottlenecks and insufficient spatial coverage. …”
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Integrated DNA Barcoding and Morphometric Characterization of Palm Weevils (Rhynchophorus spp.) in North Sulawesi by Endrile Golmen Balansa, Christina Leta Salaki, Dantje Tarore, Juliet Merry Eva Mamahit, Beivy Jonathan Kolondam, Trina Ekawati Tallei

“…This study concludes that integrating morphometric and genetic analyses reveals geographic structuring within R. vulneratus, highlighting the effectiveness of combined methods for accurate identification and population differentiation. …”
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An integrated approach to the study of Achimov deposits within the South Tambey field (Western Siberia) by A. V. Chernov, A. G. Koshcheev, E. A. Potapova, A. Y. Smirnov, A. A. Pashinskiy, A. A. Rasskazov

“…In order to clarify the structure of promising oil and gas objects in the South Tambey field (Western Siberia), an integrated approach to the study of Achimov deposits has been developed. …”
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Integrated multi-omics insight into the molecular networks of oxidative stress in triggering multiple sclerosis by Yudi Xu, Xiaowei Zhang, Yuyuan Zhang, Hongxuan Ma, Zhaokai Zhou, Hongzhuo Qin, Huimin Liu, Xinwei Han

“…To identify potential causal targets of 1216 OS-related genes for MS, a summary-data-based Mendelian randomization (SMR) method was applied. Given that genes can exert their biological functions through different omics levels, the multi-omics SMR integrating expression, methylation, and protein quantitative trait loci (eQTL, mQTL, and pQTL) of OS-related genes from blood and brain tissues was utilized. …”
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DetectEV: A functional enzymatic assay to assess integrity and bioactivity of extracellular vesicles by Giorgia Adamo, Sabrina Picciotto, Paola Gargano, Angela Paterna, Samuele Raccosta, Estella Rao, Daniele Paolo Romancino, Giulio Ghersi, Mauro Manno, Monica Salamone, Antonella Bongiovanni

“…Utilizing microalgae‐derived EVs, known as nanoalgosomes, as model systems, we optimised the assay parameters and validated its sensitivity and specificity in quantifying the enzymatic activity of esterases within the EV lumen while also evaluating EV membrane integrity. Compared to conventional methods that assess physicochemical features of EVs, our single‐step analysis efficiently detects batch‐to‐batch variations by evaluating changes in luminal cargo bioactivity and integrity across various EV samples, including differences under distinct storage conditions and following diverse isolation and exogenous loading methods, all using small sample sizes. …”
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Enhancing Secure Medical Data Communication Through Integration of LSB and DCT for Robust Analysis in Image Steganography by Ramyashree, P. S. Venugopala, S. Raghavendra, Vijay S. Kubihal

“…This method integrate audio data into medical images, specifically DICOM-standard images without compromising their visual integrity. …”
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Integrated neural network framework for multi-object detection and recognition using UAV imagery by Mohammed Alshehri, Tingting Xue, Tingting Xue, Ghulam Mujtaba, Yahya AlQahtani, Nouf Abdullah Almujally, Ahmad Jalal, Ahmad Jalal, Hui Liu, Hui Liu, Hui Liu

“…These results surpass previous benchmarks, demonstrating the system’s robust performance across diverse aerial traffic scenarios. The integration of advanced models, YOLOv11 for detection, HRNet for segmentation, Deep SORT for tracking, CSRNet for counting, LSTM for trajectory prediction, and Vision Transformers for classification enables the framework to maintain high accuracy even under challenging conditions like occlusion, variable lighting, and scale variations.DiscussionThe outcomes show that the chosen deep learning system is powerful enough to deal with the challenges of aerial vehicle analysis and gives reliable and precise results in all the aforementioned tasks. …”
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Near-field terahertz time-domain spectroscopy for in-line electrical metrology of semiconductor integration processes for memory by Sunhong Jun, Inkeun Baek, Suhwan Park, Eun Hyuk Choi, Jongmin Yoon, Iksun Jeon, Yoonkyung Jang, Martin Priwisch, Wontae Kim, Suncheul Kim, Taejoong Kim, Taeyong Jo, Myungjun Lee, Sungyoon Ryu, Namil Koo, Yusin Yang

“…The TDS signal correction method effectively suppressed signal variations in unwanted layers. …”
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Artificial Intelligence Assistive Tool for Radiotherapy Plan Evaluation Based on Analysis of Integral Dose by Shriram Rajurkar, Teerthraj Verma, MLB Bhatt, S P Mishra, P Deshmukh, D Sargar

“…Results: In this study, variation of ID between nine-beam and seven-beam plans was calculated. …”
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Grating Coupler Design for Low-Cost Fabrication in Amorphous Silicon Photonic Integrated Circuits by Daniel Almeida, Paulo Lourenço, Alessandro Fantoni, João Costa, Manuela Vieira

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A Design Approach for SoC Integration With Voltage Restoration Capability for Redundancy-Based DC Microgrids by Thales Augusto Fagundes, Raphael Sauer de Castro, Marcio Von Rondow Campos, Bruno Meneghel Zilli, Lucas Jonys Ribeiro Silva, Josep M. Guerrero, Ricardo Quadros Machado

“…Stability analysis is conducted using Lyapunov’s indirect method, and the proposed approach is supported by experimental results obtained through SpeedGoat and dSPACE platform interactions.…”
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