Stigma toward mental illness: A comparative analysis among medical and nursing students in two centers in Telangana, India by Md. Adil Faizan, V. Murali Krishna, Tialam Gautham, Govindappagari Venkata Jithendra

“…Materials and Methods: A cross-sectional study was conducted with 827 students from private medical college (Khammam) and government medical college (Warangal). …”
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Mutations associated with resistance to rifampicin and isoniazid identified in strains of the Mycobacterium tuberculosis complex by GenoType MTBDRplus in Panama, 2015–2021 by Juan Domínguez González, Juan Castillo Mewa, Prudencio González, Pedro Del Cid, Jacinto Ariel Pérez Ruíz, Samantha Eunice Rosas Hermosilla

“…The resistance patterns detected by the GenoType MTBDRplus assay highlight the genetic variability of drug resistance in the country and emphasize the need to implement epidemiological surveillance methodologies. Integrating patient clinical data with genetic variation information is essential for improving disease control and understanding transmission dynamics and drug resistance acquisition. …”
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Effectiveness and safety of light therapy for treating primary dysmenorrhea: A systematic review and meta-analysis of randomized controlled trials by Lin Ang, Eunhye Song, Sunmi Choi, Jihye Kim

“…This systematic review aimed to assess the effectiveness and safety of light therapy in individuals with primary dysmenorrhea. Methods: For this systematic review and meta-analysis, we searched twelve electronic databases, including PubMed, Cochrane Library, Embase, Allied and Complementary Medicine Database (AMED), APA PsycINFO, CINAHL Complete, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Scientific Journals Database (VIP), WanFang Data, Research Information Sharing Service (RISS), and Oriental Medicine Advanced Searching Integrated System (OASIS) to identify randomized controlled trials (RCTs) evaluating the effectiveness of light therapy for primary dysmenorrhea. …”
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Spatial distribution of paediatric tuberculosis and factors associated with adverse treatment outcomes in Ashanti Region, Ghana: a retrospective analysis by Maxwell Afranie Appiah, Mawuli Gohoho, Ebenezer Enam Adzaklo, Geoffrey Delali Komla Gone, Joshua Kwabena Aniaku, Perfect Edinam Asamoah, John Owusu Gyapong, Emmanuel Kyeremateng, Emmanuel Tinkorang

“…Additionally, the NTP should train community health workers to conduct stigma-sensitive integrated home visits for TB/HIV co-infected children to mitigate potential adverse treatment outcomes.…”
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Computational Investigation of Long Free-Span Submarine Pipelines with Buoyancy Modules Using an Automated Python–Abaqus Framework by Ty Phuor, Pavel A. Trapper, Alon Urlainis, Avshalom Ganz

“…This paper introduces an efficient and automated computational framework integrating Python scripting with Abaqus finite element analysis (FEA) to investigate the structural behavior of long free-spanning submarine pipelines equipped with buoyancy modules. …”
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STAT1β modulates the tumor immune microenvironment to improve prognosis in ovarian cancer: a comprehensive study of transcriptional and protein expression differences by Ning Lan, Xintong Li, Yifan Qiao, Siyi Zhang, Min Chen, Xiaofeng Yang, Yuliang Zou, Juan Ren, Meili Pei

“…We systematically investigated the expression patterns and prognostic relevance of STAT1 isoform-specific transcripts across pan-cancer tissues, with a particular focus on ovarian cancer (OV), and elucidated their potential mechanisms in modulating the tumor immune microenvironment (TIME) to influence patient prognosis. Methods Integrated analysis of the GTEx and TCGA databases was conducted to systematically evaluate the transcript expression profiles of STAT1 isoforms across 32 cancer types and 29 normal tissues. …”
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Forecasting motion trajectories of elbow and knee joints during infant crawling based on long–short-term memory (LSTM) networks by Jieyi Mo, Qiliang Xiong, Ying Chen, Yuan Liu, Xiaoying Wu, Nong Xiao, Wensheng Hou

“…Therefore, this paper aims to explore the feasibility of using LSTM networks to predict crawling trajectories, thereby advancing our understanding of how to actively control crawling rehabilitation training robots. Methods We collected joint trajectory data from 20 healthy infants (11 males and 9 females, aged 8–15 months) as they crawled on hands and knees. …”
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CATHODOLUMINESCENCE AND RAMAN SPECTROSCOPY AS A BASIS FOR THE SELECTION OF REFERENCE SAMPLES FOR LA-ICP-MS ANALYSIS OF ZIRCON by S. L. Votyakov, M. V. Chervyakovskaya, Yu. V. Shchapova, E. A. Pankrushina, G. B. Mikhalevsky, V. S. Chervyakovsky

“…In order to develop express methods for the quantitative assessment of properties and the selection of reference samples close to investigated sample, to ensure similar conditions for the evaporation of substances and parameters of fractionation of trace elements in LA-ICP-MS, a comparative analysis of the U-Pb isotopic composition, Raman and cathodoluminescent spectra of zircon GJ-1, Plesovice, 91500, Temora-2, Mud Tank reference samples has been performed. …”
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Evaluation of Free-Living Motor Symptoms in Patients With Parkinson Disease Through Smartwatches: Protocol for Defining Digital Biomarkers by Carlos Polvorinos-Fernández, Luis Sigcha, María Centeno-Cerrato, Guillermo de Arcas, Miriam Grande, Mayca Marín, Isabel Pareés, Juan Carlos Martínez-Castrillo, Ignacio Pavón

“… BackgroundMonitoring motor symptoms in patients with Parkinson disease (PD) presents significant challenges due to the complex nature of symptom progression, variations in medication responses, and the fluctuations that can occur throughout the day. …”
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Precision computerised cognitive behavioural therapy (cCBT) intervention for adolescents with depression (SPARX-UK): protocol for the process evaluation of a pilot randomised contr... by Charlotte Lucy Hall, Chris Hollis, Kareem Khan, Peter Fonagy, Kirsty Sprange, Cathy Creswell, Yi Yang, Vibhore Prasad, Kapil Sayal, Nitish Jawahar, Ellen Townsend, Dorothee Auer, Praveetha Patalay, Aja Murray, Yvonne Kelly, Boliang Guo, Christopher R Tench, Paul Stallard, Louise Arseneault, Sieun Lee, Sally Merry, Charlotte Hall, Jo Gregory, Rory O’Connor, Emma Nielsen, Edmund Sonuga-Barke, Hannah Wright, Petr Slovak, Emily Lloyd, Josimar De Alcantara Mendes, Carolyn Ten Holter, Marina Jirotka, Aaron Kandola, Sonia Livingstone, Kasia Kostryka-Allchorne, Jake Bourgaize, Mariya Stoilova, Marianne Etherson, Chris Greenhalgh, Jim Warren, Vajisha Wanniarachchi, Kevin Glover, Mathijs Lucassen, Karolina Stasiak, Camilla Babbage, Adam Parker, Joanna Lockwood, Elvira Perez Vallejos, Rebecca Woodcock, Sarah Doherty, Lucy-Paige Willingham, Camilla May Babbage, Matthew Jeffery, Peiyao Tang, Holly Griffiths, Lily Roberts, A. Jess Williams, Lucy Hitcham

“…This protocol paper describes the rationale, aims and methodology of the SPARX-UK trial process evaluation.Methods and analysis The process evaluation will use a mixed-methods design following the UK Medical Research Council’s 2015 guidelines, comprising quantitative and qualitative data collection. …”
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Monitoring the Ecological Security of Esfahan with an Ecosystem Service Approach by Mostafa Keshtkar, Romina Sayahnia

“…This study aimed to investigate the variations of carrying capacity and ecological security with the approach of ecosystem services in the arid and semi-arid ecosystems of Esfahan city during 2000 – 2019. 2-Materials and Methods In order to estimate the effects of man-made pressures on natural resources in Esfahan city, consumption footprint pressure index (CFPI) and production footprint pressure index (PFPI) were used based on the concept of ecological footprint. …”
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Bifidobacterium, Spirulina, and Yeast extracts in low-energy diets for rabbits: effects on performance, hematology, lipid metabolism, hepatorenal function, immunity and hormones by Mohamed S. Shaheen, Ahmed A. Allam, Usama M. Abdel Monem, Sabry M. Bassiony, Bakry A. Khalil, Ayman S. Salah, Abdullah S. Alawam, Hassan A. Rudayni, Ahmed A. Elolimy, Kasim Sakran Abass

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Mapping the Global distribution, risk factors, and temporal trends of COPD incidence and mortality (1990–2021): ecological analysis by Shafaq Naeem, Fang Wang, Rabia Mubarak, Hui Shen, Xuechun Li, Irene Mommers, Syeda Rija Hussain, Saima Shakil Malik, Chuanhua Yu, Eelko Hak, Xiaolin Xu, Muhammad Fawad, Sumaira Mubarik

“…Methods Utilizing data from the Global Burden of Disease (GBD) study, this research conducted a comprehensive ecological analysis of COPD epidemiology from 1990 to 2021. …”
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Effect of liver biopsy size on MASLD fibrosis assessment by second-harmonic generation/two-photon excitation fluorescence microscopy by Daniel T. Field, Yayun Ren, Kutbuddin Akbary, Elaine Chng, Dean Tai, Nikolai V. Naoumov, David E. Kleiner, Jonathan A. Fallowfield, Timothy J. Kendall, Arun J. Sanyal

“…Second-harmonic generation/two-photon excitation fluorescence (SHG/TPEF) microscopy images unstained tissue sections and, when integrated with artificial intelligence models, generates a continuous fibrosis value (qFibrosis) and ordinal qFibrosis stage. …”
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Identification and validation of reference genes for qPCR of Pseudomonas aeruginosa L10 under varying n-hexadecane concentrations by Huan Wang, Xiaobing Wang, Juntao Chen, Yumiao Zhang, Junhua Liu, Fangliang Xia, Jian Li, Tao Wu, Longxiang Liu

“…RefFinder provides a comprehensive assessment of reference gene stability by integrating four methods. The results indicated that among the reference genes of P. aeruginosa L10 cultured under various concentrations of n-hexadecane stress, anr had the highest Ct value and expression abundance, while tipA had the lowest. …”
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Diagnostic Predictors of Recovery Outcomes Following Open Reduction and Internal Fixation for Tibial Plateau Fractures: A Retrospective Study Based on the Schatzker Classification by Carlo Biz, Carla Stecco, Samuele Perissinotto, Xiaoxiao Zhao, Raffaele Ierardi, Luca Puce, Filippo Migliorini, Nicola Luigi Bragazzi, Pietro Ruggieri

“…<b>Conclusions</b>: Integrating diagnostic tools like PROMs, AROM, and neuromuscular performance tests provides valuable insights into recovery after ORIF for TPFs. …”
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The alteration of IL-17 signaling pathway in bipolar disorder: a preliminary study with transcriptomic perspective by Xiaobo Wang, Xiaobo Wang, Su Yu, Zhen Gao, Fangming Xu, Yumei Wang, Yumei Wang, Yumei Wang, Tianle Zhang, Tingting Xie, Xihua Jia

“…This study aims to explore global mRNA expression in Peripheral blood white cells (PBMC) of BD patients.MethodsWe analyzed whole-genome gene expression profiles from PBMC of 12 BD states-manic (BD-M), 12 BD states-depressive (BD-D), and 12 matched healthy controls (HC) using microarrays. …”
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Genotype–phenotype analysis and functional study of three novel LRP6 variants in non-syndromic oligodontia by Yunyun Yuan, Ya Zhao, Lingqiang Meng, Shuyun Zheng, Hui Li, Jiabao Ren, Beibei Li, Chenyun Dou, Yan Hou, Wenjing Chen, Jing Zhang, Jing Zhang, Yulin Ding, Yulin Ding, Wenjing Shen

“…Herein we aimed to identify novel LRP6 variants in patients with non-syndromic oligodontia (NSO) and perform functional analyses of these variants.Methods:Whole-exome sequencing (WES) was conducted on probands and their first-degree relatives to identify potential pathogenic variants. …”
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Harmonization trial on ESR1 testing strategies in ER+/HER2- breast cancer patients: an Italian experience by Francesco Pepe, Gianluca Russo, Konstantinos Venetis, Claudia Scimone, Lucia Palumbo, Mariantonia Nacchio, Domenica di Giovanni, Claudia Sarracino, Ilaria Tomaiuolo, Elisabetta Zulato, Matteo Fassan, Daniela Righi, Giuseppe Perrone, Dario de Biase, Gabriele Casati, Fabio Pagni, Lucia Gullotti, Antonio Rizzo, Alessandro Perez, Antonio Russo, Katia Zavaglia, Gianluca Gragnano, Domenico Cozzolino, Sabrina Alfano, Cristian Scatena, Sara D’andrea, Monica Schiappacassi, Giuseppina Roscigno, Alessia Paganotti, Renzo Boldorini, Francesco Esposito, Pierlorenzo Pallante, Daniela Furlan, Marta Sbaraglia, Angelo Paolo Dei Tos, Giancarlo Troncone, Nicola Fusco, Umberto Malapelle

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Multi-Stage Evaluation of Demolition and Reclamation Carbon Storage from "System Design-Construction-Quality Effect" Perspectives by Deng Pingping, Ye Changdong, Ke Chunpeng, Hu Yueming, Fu Xiaoping, Zhou Long

“…High-performing counties typically had clear task assignments, defined project timelines, integrated project management, and strong inter-program coordination. …”
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