Variants of the Coagulation and Inflammation Genes Are Replicably Associated with Myocardial Infarction and Epistatically Interact in Russians. by Rosa M Barsova, Dmitrijs Lvovs, Boris V Titov, Natalia A Matveeva, Roman M Shakhnovich, Tatiana S Sukhinina, Nino G Kukava, Mikhail Ya Ruda, Irina M Karamova, Timur R Nasibullin, Olga E Mustafina, German J Osmak, Ekaterina Yu Tsareva, Olga G Kulakova, Alexander V Favorov, Olga O Favorova

“…The procedure is applicable to any pair of logical variables, e.g. carriage of two sets of alleles. The composite model that included three single gene variants and the epistatic pair has AUC of 0.66 both in discovery and replication groups.…”
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AI driven prediction of early age compressive strength in ultra high performance fiber reinforced concrete by Mohamed Abdellatief, Wafa Hamla, Hassan Hamouda

“…Additionally, feature importance analysis was implemented to explore the influence of the input variables on the early-age CS. Results indicate that GPR and SVR models with high predictive accuracy (R2 > 0.90) outperformed ANN, RF, and GB models. …”
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A novel waste heat-driven methane reforming membrane reactor and parametric optimization study combining CFD simulation and response surface methodology by Jingyu Wang, Lei Wang, Leilei Shen, Yuqi Shen, Yuqi Wang

“…A multi-physics coupling model of the reactor was developed through computational fluid dynamics (CFD) simulations. …”
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Impact of short-term aircraft noise on cardiovascular disease risk in the area surrounding London Heathrow airport: the RISTANCO epidemiological study by Xiangpu Gong, Nicole Itzkowitz, Calvin Jephcote, Kathryn Adams, Glory O Atilola, John Gulliver, Marta Blangiardo, Anna Hansell

“…We explored relationships with three different area-level measures related to deprivation: the Carstairs index (a composite measure from UK Census variables relating to poverty), the avoidable death rate (health inequality) and fuel poverty (wealth inequality). …”
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Increasing Fire Weather Season Overlap Between North America and Australia Challenges Firefighting Cooperation by Doug Richardson, Andreia F. S. Ribeiro, Fulden Batibeniz, Yann Quilcaille, Andrea S. Taschetto, Andrew J. Pitman, Jakob Zscheischler

“…Composites of ERA5 and CMIP6 sea surface temperatures suggest a link between the interannual variability of overlap and the El Niño‐Southern Oscillation, despite this climate mode's opposing relationship with fire weather in the two regions. …”
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Chimpanzees (Pan troglodytes) Indicate Mammalian Abundance Across Broad Spatial Scales by Paul K. Kazaba, Lars Kulik, Ghislain B. Beukou Choumbou, Christelle B. Douhin Tiémoko, Funmilayo L. Oni, Serge A. Kamgang, Stefanie Heinicke, Inza Koné, Samedi Jean Pierre Mucyo, Tenekwetche Sop, Christophe Boesch, Colleen Stephens, Anthony Agbor, Samuel Angedakin, Emma Bailey, Mattia Bessone, Charlotte Coupland, Tobias Deschner, Paula Dieguez, Anne‐Céline Granjon, Briana Harder, Josephine Head, Thurston Cleveland Hicks, Sorrel Jones, Parag Kadam, Ammie K. Kalan, Kevin E. Langergraber, Juan Lapuente, Kevin C. Lee, Laura K. Lynn, Nuria Maldonado, Maureen S. McCarthy, Amelia C. Meier, Lucy Jayne Ormsby, Alex Piel, Martha M. Robbins, Lilah Sciaky, Volker Sommer, Fiona A. Stewart, Jane Widness, Roman M. Wittig, Erin G. Wessling, Mimi Arandjelovic, Hjalmar Kühl, Yntze van derHoek

“…We then fitted Bayesian Regression Models to assess potential relationships between ape detection rates (as proxy for ape abundance) and these metrics. …”
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CPFD Simulation of Operation Characteristics of a 10t/d Sludge and Biomass Co-incineration Fluidized Bed Reactor by REN Shaohui, YU Qiao, LIN Li, XIANG Jiatao, MA Lun, ZHANG Shihong

“…ObjectiveThis research aims to comprehensively investigate the operational dynamics of a 10t/d sludge and biomass co-incineration fluidized bed reactor through Computational Particle Fluid Dynamics (CPFD) modeling, addressing critical gaps in industrial-scale waste valorization. …”
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Impacts of Community Parks on Residents’ Health Benefits and Enhancement Strategies Thereof from the Perspective of Micro-Renewal: A Case Study of Nanjing by Tianyuan SHOU, Mingjuan ZHANG, Jiaxing WEI

“…The generalized ordered logit models is utilized to analyze the non-linear effects of community park characteristics on residents’ health benefits, with socio-demographic factors such as gender, age, education level, and family income as control variables.ResultsThis research reveals a hierarchical and non-linear association between community park characteristics and residents’ self-assessed health benefits. …”
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Multi-Objective Optimization Design of Dual-Spindle Component Based on Coupled Thermal–Mechanical–Vibration Collaborative Analysis by Xiaoliang Lin, Yiming Xie, Xiaolei Deng, Jing Tian, Yue Han, Peng Wang

“…The dual-spindle component of a CNC machine tool is taken as the parameterized model. According to the theories of thermal characteristics, statics, and dynamics, the solution of thermal-mechanical coupling deformation and the solution of vibration characteristics under prestress are repeatedly conducted, that are working collaboratively with each process of parameters sensitivity computing, selection of design variables, central composite design, and multi-objective joint optimization. …”
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Panoramic spatial enhanced resolution proteomics (PSERP) reveals tumor architecture and heterogeneity in gliomas by Ziyan Xu, Yunzhi Wang, Tao Xie, Rongkui Luo, Heng-Li Ni, Hang Xiang, Shaoshuai Tang, Subei Tan, Rundong Fang, Peng Ran, Qiao Zhang, Xiaomeng Xu, Sha Tian, Fuchu He, Wenjun Yang, Chen Ding

“…The PSERP approach facilitates rapid quantitative profiling of proteomic spatial variability in whole tissue sections at sub-millimeter resolution. …”
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Multi-objective optimization of laser spot welding parameters for enhancing mechanical properties of hard disk components using response surface methodology by K. Chimklin, S. Phuangkaew, J. Deeying

“…The parameters considered include outer diameter (OD), inner diameter (ID), penetration, and tip height. Through a central composite design matrix experiment and quadratic modeling, empirical mathematical models were established to predict the response variables. …”
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A nomogram to predict sarcopenia in middle-aged and older women: a nationally representative survey in China by Jiayi Yang, Zihao Chen, Xinxin Dai, Liyao Jiang, Liyan Dai, Yu Zhao

“…In addition, this study integrated these sarcopenia-related variables into a comprehensive index, and ROC analysis results showed that the AUC of the composite index was 0.738.ConclusionsThis study found that sarcopenia in Chinese women may be closely related to age, waist, education, marriage, area, stroke, physical pain, depression, and region. …”
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Assessment of quality of maternal and newborn care and its determinants: a national study of primary health care facilities in Nigeria by Toluwani Oluwatola, Saheed Dipo Isiaka, Oluomachukwu Omeje, Folake Oni, Olugbemisola W. Samuel, Sidney Sampson, Hilda Ebinim, Oluwadamilare Olatunji, Oluwafisayo Ayodeji, Dolapo Ajibola, Stallone Ngobua, Oluwafunmilayo Dehinbo, Helen Ukoh, Leyira Ken-Aminikpo, Segun Adenipekun, Hilary I. Okagbue

“…There were significant variations in the mean PHC facility QoC across states, with Katsina and Ondo states having the lowest (1.35) and highest (2.98) QoC, respectively. The regression model showed that the contextual variables analyzed accounted for 31.5% of the variation in QoC, with varying statistically significant relationships with the QoC. …”
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Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients by Yanping Guan, Bilian Li, Yiyu Zhang, Hao Luo, Xueding Wang, Xue Bai, Zhuoling Zheng, Yaying Huang, Wei Wei, Min Huang, Xingrong Song, Guoping Zhong

“…A validated population pharmacokinetic model was used to estimate pharmacokinetic parameters. …”
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Removal of chromium from synthetic wastewater by electrocoagulation and using natural coagulant (blend of hen eggshell powder with lime): optimization of response surface methodolo... by Werkne Sorsa Muleta, Firomsa Bidira Abdi, Endrias Adane Bekele

“…In this work, the removal of Cr from synthetic wastewater by electrocoagulation supported by natural coagulant (eggshell powder) with aluminum electrodes was investigated. The central composite design of the response surface methodology was employed to estimate and optimize process variables, such as initial Cr concentration (225–475 mg/L), solution pH (5–9), and current density (0.35–045 A/m2), and treatment time (30–40 min) with an electrode distance (ED) of 0.5 and 1 cm, respectively. 99.90% and 99.74% of removal efficiencies were observed at initial Cr concentration of 456.11 mg/L, a solution pH of 5.45, with current density of 0.47 A/m2, and treatment time of 36.84 min. …”
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Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort. by Chris Lauber, Mathias J Gerl, Christian Klose, Filip Ottosson, Olle Melander, Kai Simons

“…Risk stratification was further improved by adding standard clinical variables to the model, resulting in a case rate of 51.0% and 53.3% in the highest risk group for T2D and CVD, respectively. …”
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Predicting incident type 2 diabetes in a Japanese cohort: an 8-year analysis of the NAGALA database by Yangchun Wang, Fei Liu, Ruixiang Tong, Zhonghua He, Qin Fang, Jie Feng, Hongliang An, Junjun Liu

“…The ability of individual components and a composite risk score to discriminate was assessed using Receiver Operating Characteristic (ROC) curves.ResultsOver an average follow-up duration of 2207.82 ± 1379.73 days, 262 patients (1.7%) had the onset of T2DM. …”
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Rapid Discrimination for Traditional Complex Herbal Medicines from Different Parts, Collection Time, and Origins Using High-Performance Liquid Chromatography and Near-Infrared Spec... by Haiyan Fu, Yao Fan, Xu Zhang, Hanyue Lan, Tianming Yang, Mei Shao, Sihan Li

“…By comparing component analysis (PCA), linear discriminant analysis (LDA), and particularly partial least squares discriminant analysis (PLSDA) with different fingerprint preprocessing of NIR spectra variables, PLSDA model showed perfect functions on the analysis of samples as well as chromatograms. …”
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Topical Steroids and Antibiotics for Adult Blepharokeratoconjunctivitis (BKC): A Meta-Analysis of Randomized Clinical Trials by Lu Zhao, Ya-jie Sun, Zhi-qiang Pan

“…The pooled effect sizes were analyzed using 95% confidence intervals (CIs) in a fixed-effect model. Heterogeneity was evaluated using the Q-test and I2 statistic. …”
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Dispersive micro-solid phase extraction coupled with spectrophotometric using (MgFe CLDH)/GO magnetically separable sorbent for pre-concentration of anionic food dyes in water samp... by Zarin Mohammadi, Mohammad Mehdi Sabzehmeidani, Mehrorang Ghaedi, Kheibar Dashtian, Hamid Abbasi-Asl

“…Then, the extracted SY and TZ dyes were analyzed by UV–vis spectrophotometer. Main variables related to the extraction process including pH, nano composite mass, sonication and vortex time and eluent volume were optimized by central composite design (CCD). …”
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