A multiplex method for rapidly identifying viral protease inhibitors by Seo Jung Hong, Samuel J Resnick, Sho Iketani, Ji Won Cha, Benjamin Alexander Albert, Christopher T Fazekas, Ching-Wen Chang, Hengrui Liu, Shlomi Dagan, Michael R Abagyan, Pavla Fajtová, Bruce Culbertson, Brooklyn Brace, Eswar R Reddem, Farhad Forouhar, J Fraser Glickman, James M Balkovec, Brent R Stockwell, Lawrence Shapiro, Anthony J O’Donoghue, Yosef Sabo, Joel S Freundlich, David D Ho, Alejandro Chavez

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Ultramodern natural and synthetic polymer hydrogel scaffolds for articular cartilage repair and regeneration by Chun-Sheng Li, Yan Xu, Juan Li, Shu-Hao Qin, Shao-Wen Huang, Xue-Mei Chen, Yi Luo, Cheng-Tao Gao, Jian-Hui Xiao

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Gut microbiota derived DCA enhances FOLFOX efficacy via Ugt1a6b mediated enterohepatic circulation in colon cancer by Qian Fang, Xiaoying Hou, Limei Fan, Yufei Deng, Xiaoxuan Li, Hongyun Zhang, Haiping Wang, Zhengqi Fu, Binlian Sun, Xiji Shu, Hongzhi Du, Yuchen Liu

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Characterization of mammary glands and milk fat globule transcripts in lactating buffalo and goats by Hancai Jiang, Xiaoxian Xu, Shuwan Wang, Xinhui Song, Ling Li, Qingyou Liu, Kuiqing Cui, Deshun Shi, Jian Wang, Hui Li, Jieping Huang, Zhipeng Li

“…Among 6086 lncRNAs and 7010 miRNAs identified, 35 % and 50 % were differentially expressed, respectively. Of 11,631 circRNAs, only 618 showed significant differences. …”
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Learning experience on sentinel cases of COVID-19 at a public healthcare institution: sharing on operating room processes by Frederick H Koh, Keen-Chong Chau, Siok-Peng Ng, Li-Ming Teo, Sharon GK Ong, Wai-Keong Wong, Biauw-Chi Ong, Min-Hoe Chew

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Operative Time Learning Curve for an Image-Free Robotic Arm Assisted Total Knee Arthroplasty: A Cumulative Sum Analysis by Cale A. Pagan, MD, Theofilos Karasavvidis, MD, Breana Siljander, MD, Eytan M. Debbi, MD, PhD, Charles A. DeCook, MD, Jonathan Vigdorchik, MD

“…Mean surgical time for RA-TKA was 42.4 ± 8.7 minutes, compared to 35.3 ± 7.0 minutes for M-TKA (P < .001). Early RA-TKA cases (1-20) had significantly longer times than late RA-TKA cases (61-80) and M-TKA cases (P < .05). …”
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Reinforcing cancer immunotherapy with engineered porous hollow mycobacterium tuberculosis loaded with tumor neoantigens by Jie Jiang, Feng-Ying Huang, Shu-Zhen Dai, Guang-Hong Tan, Ming-Hui Chen, Hengyu Chen, Wu-Ping Zheng, Ri-Hong Wu, Weijing Xie

“…The efficacy of phMTb vaccine formulations in combination with anti-programmed cell death protein 1 (PD-1) antibody therapy was assessed using the MC38 mouse tumor models. …”
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β-synuclein in cerebrospinal fluid as a potential biomarker for distinguishing human prion diseases from Alzheimer’s and Parkinson’s disease by Bing Xu, Kang Xiao, Xiaoxi Jia, Rundong Cao, Donglin Liang, Ruhan A, Weiwei Zhang, Chunjie Li, Liping Gao, Cao Chen, Qi Shi, Xiaoping Dong

“…The diagnostic groups of the 223 patients with PrDs included sporadic Creutzfeldt-Jacob disease (sCJD), genetic CJD (gCJD), fatal familial insomnia (FFI) and Gerstmann-Straussler-Scheinker (GSS). 91 patients with non-PrDs comprised Alzheimer’s disease (AD), Parkinson's disease (PD), viral encephalitis (VE) or autoimmune encephalitis (AE) were enrolled in the control groups. …”
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Advancing Alzheimer’s disease risk prediction: development and validation of a machine learning-based preclinical screening model in a cross-sectional study by Yanfei Chen, Bing Wang, Yankai Shi, Wenhao Qi, Shihua Cao, Bingsheng Wang, Ruihan Xie, Jiani Yao, Xiajing Lou, Chaoqun Dong, Xiaohong Zhu, Danni He

“…An oversampling method was applied to balance the data set.Interventions This study has no interventions.Participants The study included 2379 participants, of whom 507 were diagnosed with AD.Primary and secondary outcome measures Including accuracy, precision, recall, F1 score, etc.Results 11 variables were critical in the training phase, including educational level, depression, insomnia, age, Body Mass Index (BMI), medication count, gender, stenting, systolic blood pressure (sbp), neurosis and rapid eye movement. …”
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A Pragmatic Clinical Trial to Compare the Real-World Effectiveness of V-Go versus Standard Delivery of Insulin in Patients with Advanced Type 2 Diabetes by Mark J. Cziraky, Scott Abbott, Matt Nguyen, Kay Larholt, Elizabeth Apgar, Thomas Wasser, Poul Strange, Leon Shi, H. Courtenay Harrison, Beverly Everitt, Lynn Nowak

“…HbA1c decreased from baseline to EOS in both V-Go (-1.0%, p<.001) and STO (-0.5%, p<.001); V-Go had significantly larger decrease (p=.002). …”
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Regulation of Yield and Eating and Cooking Quality in Rice Through Seed Albumin OsRAL5 by Zhao Chunfang, He Lei, Guan Ju, Luo Lei, Zhao Ling, Zhou Lihui, Yao Shu, Chen Tao, Zhu Zhen, Zhao Qingyong, Wang Cailin, Zhang Yadong

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A rare case of vision loss caused by leptomeningeal metastasis of lung adenocarcinoma: a case report and literature review by Zhihua Li, Jian Chu, Wennan Shen, Junnan Chen, Yuemei Dong, Manze Zhang, Nan Zhao, Wei Zhao, Haoran Zha, Ning Wang, Yalin Han, Zhaoxia Li

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Breaking linear scaling relationships in oxygen evolution via dynamic structural regulation of active sites by Zheye Zhang, Hongyan Zhao, Shibo Xi, Xiaoxu Zhao, Xiao Chi, Hong Bin Yang, Zhongxin Chen, Xiaojiang Yu, Yang-Gang Wang, Bin Liu, Peng Chen

“…We construct a model Ni-Fe2 molecular catalyst via in situ electrochemical activation, which is able to deliver a notable intrinsic oxygen evolution reaction activity. …”
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Schizophrenia recognition based on three-dimensional adaptive graph convolutional neural network by Guimei Yin, Jie Yuan, Yanjun Chen, Guangxing Guo, Dongli Shi, Lin Wang, Zilong Zhao, Yanli Zhao, Manjie Zhang, Yuan Dong, Bin Wang, Shuping Tan

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Newer Generation of Scooters: Polychlorinated Dibenzo-p-dioxin and Dibenzofuran and Polychlorinated Biphenyl Reductions by Hung-Hong Chen, Yun-Hwei Shen, Hsi-Hsien Yang, Jau-Huai Lu, Lin-Chi Wang, Yen-Kung Hsieh, Chia-Fon Lee, Sheng-Lun Lin

“…Tier 5 and 6 scooters emitted 1.86–2.91 and 0.133–0.298 pg WHO-TEQ Nm−3 of PCDD/Fs and PCBs, respectively. …”
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Hamstring Activity Before and After Break-Point Angle Calculated By Smartphone Application During the Nordic Hamstring Exercise by Toshiaki Soga, Shota Yamaguchi, Takayuki Inami, Hiromi Saito, Nadaka Hakariya, Naoto Nakaichi, Sho Shinohara, Koki Sasabe, Hayato Nakamura, Teerapat Laddawong, Kei Akiyama, Norikazu Hirose

“…The peak value of the BF EMG activity during the prone leg curl was used to convert BF EMG activity during NHE to %MVIC. BPA during NHE was calculated using the Nordic Angle app by analyzing a movie recorded with an iPhone camera. …”
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Oxidative impact on lipoprotein structure: Insights from dynamic light scattering by Nickolette Kong, Natalia Penaloza, Gustavo Agreda, Angela B. Nguyen, Joseph Gutheinz, Alison Tran, Nhi Nguyen, Tuong Vi Ho, Ana Marin, Birgit Mellis, Richa Chandra

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Striking a balance between aesthetics and safety: a comparative study on the maternal and neonatal outcomes of mini-incision cesarean section by ChunLan Yuan, ShiMei He, WenQian Jian, MeiRong He, HuiFang Huang, JianChun Huang, MeiPing He, KaiSun Zhao

“…Methods A total of 99 pregnant women with full-term singleton pregnancies, who delivered at the Second Nanning People's Hospital from January 2024 to September 2024, were enrolled in this study. …”
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Enhanced brightness and photostability of dye-sensitized Nd-doped rare earth nanocomposite for in vivo NIR-IIb vascular and orthotopic tumor imaging by Syue-Liang Lin, Shih-Po Su, Yuan-Zhen Yang, Cheng-Yu Chiang, Hsin-Yu Chi, Cheng Allen Chang, Tse-Ying Liu, Huihua Kenny Chiang

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Rapid aging of influenza epidemics in China from 2005/06 to 2016/17: A population-based study by Weibo Tang, Hao Lei, Nan Zhang, Yaojing Wang, Shimeng Cai, Shuyi Ji, Lei Yang, Mengya Yang, Can Chen, Shigui Yang, Dayan Wang, Yuelong Shu

“…The aging of patients infected with influenza B/Yamagata was the most rapid, with a mean age increase of 0.73 years per year, followed by those infected with influenza A (H1N1) and influenza A (H3N2). Conversely, there was no significant increase in the mean age of patients infected with influenza B/Victoria. …”
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